TWI491604B - 作為組織胺ｈ3受體調節劑之環烷基氧基－及雜環烷基氧基吡啶化合物 - Google Patents
作為組織胺ｈ3受體調節劑之環烷基氧基－及雜環烷基氧基吡啶化合物 Download PDFInfo
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- TWI491604B TWI491604B TW097144606A TW97144606A TWI491604B TW I491604 B TWI491604 B TW I491604B TW 097144606 A TW097144606 A TW 097144606A TW 97144606 A TW97144606 A TW 97144606A TW I491604 B TWI491604 B TW I491604B
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- Prior art keywords
- yloxy
- pyridin
- tetrahydro
- methanone
- cyclobutyl
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Classifications
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- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
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| Application Number | Priority Date | Filing Date | Title |
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| US98924607P | 2007-11-20 | 2007-11-20 |
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| TW200936579A TW200936579A (en) | 2009-09-01 |
| TWI491604B true TWI491604B (zh) | 2015-07-11 |
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| TW097144606A TWI491604B (zh) | 2007-11-20 | 2008-11-19 | 作為組織胺ｈ3受體調節劑之環烷基氧基－及雜環烷基氧基吡啶化合物 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0324159D0 (en) | 2003-10-15 | 2003-11-19 | Glaxo Group Ltd | Novel compounds |
| US8288389B2 (en) * | 2007-09-06 | 2012-10-16 | Glaxo Group Limited | Piperazine derivative having affinity for the histamine H3 receptor |
| US20090318380A1 (en) | 2007-11-20 | 2009-12-24 | Pharmasset, Inc. | 2',4'-substituted nucleosides as antiviral agents |
| BRPI0913057A2 (pt) * | 2008-05-08 | 2015-10-13 | Evotec Ag | azetidinas e ciclobutanos como antagonistas de receptor de histamina h3 |
| PL3216784T3 (pl) * | 2009-03-18 | 2019-07-31 | Janssen Pharmaceutica Nv | Sposób wytwarzania modulatorów receptorów histaminowych H3 |
| CN102638979A (zh) * | 2009-09-21 | 2012-08-15 | 范德比尔特大学 | 作为mGluR5 正变构调节剂的邻苄基烟酰胺 |
| US20140142070A1 (en) | 2011-07-07 | 2014-05-22 | Janssen R&D Ireland | Darunavir combination formulations |
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| JP2002322163A (ja) * | 2001-04-20 | 2002-11-08 | Sumitomo Pharmaceut Co Ltd | ピペラジン誘導体 |
| WO2005040144A1 (en) * | 2003-10-15 | 2005-05-06 | Glaxo Group Limited | Novel compounds |
| US20070167435A1 (en) * | 2005-12-21 | 2007-07-19 | Schering Corporation | Phenoxypiperidines and analogs thereof useful as histamine H3 antagonists |
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2008
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002322163A (ja) * | 2001-04-20 | 2002-11-08 | Sumitomo Pharmaceut Co Ltd | ピペラジン誘導体 |
| WO2005040144A1 (en) * | 2003-10-15 | 2005-05-06 | Glaxo Group Limited | Novel compounds |
| US20070167435A1 (en) * | 2005-12-21 | 2007-07-19 | Schering Corporation | Phenoxypiperidines and analogs thereof useful as histamine H3 antagonists |
Also Published As
| Publication number | Publication date |
|---|---|
| EA201070637A1 (ru) | 2010-12-30 |
| WO2009067401A1 (en) | 2009-05-28 |
| AR110977A2 (es) | 2019-05-22 |
| NI201000086A (es) | 2011-03-17 |
| AU2008326561B2 (en) | 2013-12-05 |
| EP2222664A1 (en) | 2010-09-01 |
| KR101546712B1 (ko) | 2015-08-24 |
| EP2222664B1 (en) | 2014-10-29 |
| CA2706328C (en) | 2016-04-19 |
| JP5498390B2 (ja) | 2014-05-21 |
| CN105712977A (zh) | 2016-06-29 |
| CN101868454A (zh) | 2010-10-20 |
| UA103468C2 (ru) | 2013-10-25 |
| MX2010005488A (es) | 2010-06-01 |
| JP2011503233A (ja) | 2011-01-27 |
| MY158253A (en) | 2016-09-30 |
| CO6210700A2 (es) | 2010-10-20 |
| CL2008003465A1 (es) | 2009-03-06 |
| CR11529A (es) | 2012-10-25 |
| HK1147994A1 (en) | 2011-08-26 |
| ECSP10010190A (es) | 2010-06-29 |
| NZ584998A (en) | 2012-08-31 |
| US8883776B2 (en) | 2014-11-11 |
| TW200936579A (en) | 2009-09-01 |
| ZA201004334B (en) | 2011-10-26 |
| KR20100098636A (ko) | 2010-09-08 |
| US20090131415A1 (en) | 2009-05-21 |
| AU2008326561A1 (en) | 2009-05-28 |
| BRPI0820481A2 (pt) | 2015-06-16 |
| CA2706328A1 (en) | 2009-05-28 |
| EA018582B1 (ru) | 2013-09-30 |
| AR069387A1 (es) | 2010-01-20 |
| CN105712977B (zh) | 2021-06-29 |
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