NI201000086A - Compuestos de cicloalquiloxi y heterocicloalquiloxipiridina como moduladores del receptor h3 de histamina. - Google Patents
Compuestos de cicloalquiloxi y heterocicloalquiloxipiridina como moduladores del receptor h3 de histamina.Info
- Publication number
- NI201000086A NI201000086A NI201000086A NI201000086A NI201000086A NI 201000086 A NI201000086 A NI 201000086A NI 201000086 A NI201000086 A NI 201000086A NI 201000086 A NI201000086 A NI 201000086A NI 201000086 A NI201000086 A NI 201000086A
- Authority
- NI
- Nicaragua
- Prior art keywords
- histamine
- receptor
- cycloalkyloxy
- compounds
- heterocloalkyloxypyridine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Addiction (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Anesthesiology (AREA)
- Ophthalmology & Optometry (AREA)
- Nutrition Science (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Ciertos compuestos de cicloalquiloxi y heterocicloalquiloxipiridina son moduladores del receptor H3 de Histamina útiles en el tratamiento de las enfermedades mediadas por el receptor H3 de histamina.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US98924607P | 2007-11-20 | 2007-11-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
NI201000086A true NI201000086A (es) | 2011-03-17 |
Family
ID=40297867
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NI201000086A NI201000086A (es) | 2007-11-20 | 2010-05-18 | Compuestos de cicloalquiloxi y heterocicloalquiloxipiridina como moduladores del receptor h3 de histamina. |
Country Status (23)
Country | Link |
---|---|
US (1) | US8883776B2 (es) |
EP (1) | EP2222664B1 (es) |
JP (1) | JP5498390B2 (es) |
KR (1) | KR101546712B1 (es) |
CN (2) | CN105712977B (es) |
AR (2) | AR069387A1 (es) |
AU (1) | AU2008326561B2 (es) |
BR (1) | BRPI0820481A2 (es) |
CA (1) | CA2706328C (es) |
CL (1) | CL2008003465A1 (es) |
CO (1) | CO6210700A2 (es) |
CR (1) | CR11529A (es) |
EA (1) | EA018582B1 (es) |
EC (1) | ECSP10010190A (es) |
HK (1) | HK1147994A1 (es) |
MX (1) | MX2010005488A (es) |
MY (1) | MY158253A (es) |
NI (1) | NI201000086A (es) |
NZ (1) | NZ584998A (es) |
TW (1) | TWI491604B (es) |
UA (1) | UA103468C2 (es) |
WO (1) | WO2009067401A1 (es) |
ZA (1) | ZA201004334B (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0324159D0 (en) | 2003-10-15 | 2003-11-19 | Glaxo Group Ltd | Novel compounds |
US8288389B2 (en) * | 2007-09-06 | 2012-10-16 | Glaxo Group Limited | Piperazine derivative having affinity for the histamine H3 receptor |
US20090318380A1 (en) | 2007-11-20 | 2009-12-24 | Pharmasset, Inc. | 2',4'-substituted nucleosides as antiviral agents |
CA2721303C (en) * | 2008-05-08 | 2016-06-28 | Evotec Ag | Azetidines and cyclobutanes as histamine h3 receptor antagonists |
EP3216784B1 (en) | 2009-03-18 | 2018-12-26 | Janssen Pharmaceutica NV | Process for the preparation of histamine h3 receptor modulators |
BR112012006330A2 (pt) * | 2009-09-21 | 2017-07-04 | Janssen Cilag S A | análogos de o-benzil nicotinamida como moduladores alostéricos positivos de mglur5 |
DK2729130T3 (en) | 2011-07-07 | 2017-12-11 | Janssen Sciences Ireland Uc | Darunavir-COMBINATION FORMULATIONS |
Family Cites Families (55)
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DE817911C (de) | 1947-12-16 | 1951-10-22 | Chem Fab Tempelhof Preuss & Te | Verfahren zur Darstellung von in 6-Stellung basisch substituierten Pyridin-3-carbonsaeureamiden |
JPS4420347Y1 (es) | 1966-05-31 | 1969-09-01 | ||
JPS4637595Y1 (es) | 1967-02-18 | 1971-12-25 | ||
BE726551A (es) | 1968-01-22 | 1969-06-16 | ||
ES436109A1 (es) | 1974-04-04 | 1977-01-01 | Christiaens Sa A | Procedimiento para la preparacion de nuevos derivados de pi-ridina. |
EP0089765A3 (en) | 1982-03-17 | 1984-05-23 | Smith Kline & French Laboratories Limited | Pyridine derivatives |
GB8311443D0 (en) | 1983-04-27 | 1983-06-02 | Smith Kline French Lab | Chemical compounds |
GB8320505D0 (en) | 1983-07-29 | 1983-09-01 | Smith Kline French Lab | Chemical compounds |
GB8332091D0 (en) | 1983-12-01 | 1984-01-11 | Smith Kline French Lab | Chemical compounds |
JPS61149119A (ja) | 1984-12-22 | 1986-07-07 | 旭光学工業株式会社 | 検眼用試験枠 |
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CZ20013000A3 (cs) | 1999-02-26 | 2002-02-13 | Merck & Co., Inc. | Nové sulfonamidové sloučeniny a jejich pouľití |
KR100722090B1 (ko) | 1999-05-21 | 2007-05-25 | 바이오비트럼 에이비 | 신규 화합물, 이의 용도 및 이의 제조 방법 |
US6399607B1 (en) | 1999-07-02 | 2002-06-04 | Research Foundation-State University Of New York | Aminomethylene amide analogs of pyrazinamide with intracellular antimycobacterial activity against pyrazinamide-resistant mycobacteria combined with a rifamycin |
DE10023492A1 (de) | 2000-05-09 | 2001-11-22 | Schering Ag | Aza- und Polyazanthranylamide und deren Verwendung als Arzneimittel |
US6645990B2 (en) | 2000-08-15 | 2003-11-11 | Amgen Inc. | Thiazolyl urea compounds and methods of uses |
US6995162B2 (en) | 2001-01-12 | 2006-02-07 | Amgen Inc. | Substituted alkylamine derivatives and methods of use |
JP2002322163A (ja) | 2001-04-20 | 2002-11-08 | Sumitomo Pharmaceut Co Ltd | ピペラジン誘導体 |
US7067507B2 (en) * | 2001-06-12 | 2006-06-27 | Pharmacia & Upjohn Company | Macrocycles useful in the treatment of Alzheimer's disease |
RU2285002C2 (ru) | 2001-06-15 | 2006-10-10 | Астеллас Фарма Инк. | Производное пиридина и фармацевтическая композиция на его основе |
US7208497B2 (en) | 2001-07-02 | 2007-04-24 | Novo Nordisk A/S | Substituted piperazines and diazepanes |
JP2005502623A (ja) | 2001-07-02 | 2005-01-27 | ノボ ノルディスク アクティーゼルスカブ | 置換ピペラジンおよびジアゼパン |
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WO2005023247A1 (en) | 2003-09-03 | 2005-03-17 | Smithkline Beecham Corporation | Compounds and methods |
GB0324159D0 (en) * | 2003-10-15 | 2003-11-19 | Glaxo Group Ltd | Novel compounds |
DE602005025222D1 (de) | 2004-03-31 | 2011-01-20 | Janssen Pharmaceutica Nv | Heterocyclische nichtimidazolverbindungen als modulatoren des histamin-h3-rezeptors |
MXPA06011414A (es) * | 2004-03-31 | 2007-04-20 | Johnson & Johnson | Compuestos heterociclicos sin imidazol como ligandos del receptor de h3 histamina. |
GB0514812D0 (en) | 2005-07-19 | 2005-08-24 | Glaxo Group Ltd | Compounds |
AU2006292598B2 (en) | 2005-09-16 | 2012-06-21 | Janssen Pharmaceutica N.V. | Cyclopropyl amines as modulators of the histamine H3 receptor |
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CA2634847A1 (en) * | 2005-12-21 | 2007-07-05 | Schering Corporation | Substituted aniline derivatives useful as histamine h3 antagonists |
BRPI0709612A2 (pt) | 2006-03-15 | 2011-07-19 | Wyeth Corp | composto de fórmula i; método para o tratamento de um distúrbio no sistema nervoso central relacionado ou afetado pelo receptor histamina-3 em um paciente que necessita deste tratamento; método para a inibição do receptor h3; composição farmacêutica; e processo para a preparação de um composto de fórmula i |
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CN101511807A (zh) * | 2006-06-29 | 2009-08-19 | 詹森药业有限公司 | 组胺h3受体的取代的苯甲酰胺调节剂 |
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-
2008
- 2008-11-17 UA UAA201007603A patent/UA103468C2/ru unknown
- 2008-11-17 BR BRPI0820481-0A patent/BRPI0820481A2/pt not_active IP Right Cessation
- 2008-11-17 CA CA2706328A patent/CA2706328C/en active Active
- 2008-11-17 MY MYPI2010002288A patent/MY158253A/en unknown
- 2008-11-17 JP JP2010535014A patent/JP5498390B2/ja not_active Expired - Fee Related
- 2008-11-17 CN CN201610094782.9A patent/CN105712977B/zh not_active Expired - Fee Related
- 2008-11-17 KR KR1020107013252A patent/KR101546712B1/ko active IP Right Grant
- 2008-11-17 AU AU2008326561A patent/AU2008326561B2/en not_active Ceased
- 2008-11-17 WO PCT/US2008/083764 patent/WO2009067401A1/en active Application Filing
- 2008-11-17 US US12/272,268 patent/US8883776B2/en not_active Expired - Fee Related
- 2008-11-17 EP EP08852442.6A patent/EP2222664B1/en not_active Not-in-force
- 2008-11-17 NZ NZ584998A patent/NZ584998A/xx not_active IP Right Cessation
- 2008-11-17 EA EA201070637A patent/EA018582B1/ru unknown
- 2008-11-17 CN CN200880117055A patent/CN101868454A/zh active Pending
- 2008-11-17 MX MX2010005488A patent/MX2010005488A/es active IP Right Grant
- 2008-11-19 TW TW097144606A patent/TWI491604B/zh not_active IP Right Cessation
- 2008-11-20 CL CL2008003465A patent/CL2008003465A1/es unknown
- 2008-11-20 AR ARP080105055A patent/AR069387A1/es not_active Application Discontinuation
-
2010
- 2010-05-18 NI NI201000086A patent/NI201000086A/es unknown
- 2010-05-19 EC EC2010010190A patent/ECSP10010190A/es unknown
- 2010-05-20 CO CO10060285A patent/CO6210700A2/es active IP Right Grant
- 2010-06-18 ZA ZA2010/04334A patent/ZA201004334B/en unknown
- 2010-06-21 CR CR11529A patent/CR11529A/es not_active Application Discontinuation
-
2011
- 2011-02-28 HK HK11101993.2A patent/HK1147994A1/xx not_active IP Right Cessation
-
2018
- 2018-02-14 AR ARP180100346A patent/AR110977A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
CA2706328A1 (en) | 2009-05-28 |
MX2010005488A (es) | 2010-06-01 |
EA018582B1 (ru) | 2013-09-30 |
US8883776B2 (en) | 2014-11-11 |
CR11529A (es) | 2012-10-25 |
BRPI0820481A2 (pt) | 2015-06-16 |
AU2008326561A1 (en) | 2009-05-28 |
AU2008326561B2 (en) | 2013-12-05 |
EA201070637A1 (ru) | 2010-12-30 |
EP2222664A1 (en) | 2010-09-01 |
TWI491604B (zh) | 2015-07-11 |
EP2222664B1 (en) | 2014-10-29 |
KR20100098636A (ko) | 2010-09-08 |
ECSP10010190A (es) | 2010-06-29 |
KR101546712B1 (ko) | 2015-08-24 |
US20090131415A1 (en) | 2009-05-21 |
CN101868454A (zh) | 2010-10-20 |
CN105712977A (zh) | 2016-06-29 |
JP2011503233A (ja) | 2011-01-27 |
HK1147994A1 (en) | 2011-08-26 |
NZ584998A (en) | 2012-08-31 |
CA2706328C (en) | 2016-04-19 |
JP5498390B2 (ja) | 2014-05-21 |
AR110977A2 (es) | 2019-05-22 |
TW200936579A (en) | 2009-09-01 |
AR069387A1 (es) | 2010-01-20 |
MY158253A (en) | 2016-09-30 |
CN105712977B (zh) | 2021-06-29 |
ZA201004334B (en) | 2011-10-26 |
CL2008003465A1 (es) | 2009-03-06 |
CO6210700A2 (es) | 2010-10-20 |
UA103468C2 (ru) | 2013-10-25 |
WO2009067401A1 (en) | 2009-05-28 |
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