UA103468C2 - Соединения циклоалкилокси- и гетероциклоалкилоксипиридина как модуляторы гистаминового рецептора н3 - Google Patents
Соединения циклоалкилокси- и гетероциклоалкилоксипиридина как модуляторы гистаминового рецептора н3Info
- Publication number
- UA103468C2 UA103468C2 UAA201007603A UAA201007603A UA103468C2 UA 103468 C2 UA103468 C2 UA 103468C2 UA A201007603 A UAA201007603 A UA A201007603A UA A201007603 A UAA201007603 A UA A201007603A UA 103468 C2 UA103468 C2 UA 103468C2
- Authority
- UA
- Ukraine
- Prior art keywords
- histamine
- cycloalkyloxy
- modulators
- receptor
- heterocycloalkyloxypyridine
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Abstract
Некоторые соединения циклоалкилокси- и гетероциклоалкилоксипиридина являются модуляторами гистаминового рецептора Н, применимыми при лечении заболеваний, опосредованных гистаминовым рецептором Н.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US98924607P | 2007-11-20 | 2007-11-20 | |
PCT/US2008/083764 WO2009067401A1 (en) | 2007-11-20 | 2008-11-17 | Cycloalkyloxy-and hetξrocycloalky- loxypyridine compounds as modulators of the histamine h3 receptor |
Publications (1)
Publication Number | Publication Date |
---|---|
UA103468C2 true UA103468C2 (ru) | 2013-10-25 |
Family
ID=40297867
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA201007603A UA103468C2 (ru) | 2007-11-20 | 2008-11-17 | Соединения циклоалкилокси- и гетероциклоалкилоксипиридина как модуляторы гистаминового рецептора н3 |
Country Status (23)
Country | Link |
---|---|
US (1) | US8883776B2 (ru) |
EP (1) | EP2222664B1 (ru) |
JP (1) | JP5498390B2 (ru) |
KR (1) | KR101546712B1 (ru) |
CN (2) | CN105712977B (ru) |
AR (2) | AR069387A1 (ru) |
AU (1) | AU2008326561B2 (ru) |
BR (1) | BRPI0820481A2 (ru) |
CA (1) | CA2706328C (ru) |
CL (1) | CL2008003465A1 (ru) |
CO (1) | CO6210700A2 (ru) |
CR (1) | CR11529A (ru) |
EA (1) | EA018582B1 (ru) |
EC (1) | ECSP10010190A (ru) |
HK (1) | HK1147994A1 (ru) |
MX (1) | MX2010005488A (ru) |
MY (1) | MY158253A (ru) |
NI (1) | NI201000086A (ru) |
NZ (1) | NZ584998A (ru) |
TW (1) | TWI491604B (ru) |
UA (1) | UA103468C2 (ru) |
WO (1) | WO2009067401A1 (ru) |
ZA (1) | ZA201004334B (ru) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
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GB0324159D0 (en) | 2003-10-15 | 2003-11-19 | Glaxo Group Ltd | Novel compounds |
US20090170869A1 (en) * | 2007-09-06 | 2009-07-02 | Desmond John Best | Piperazine derivative having affinity for the histamine h3 receptor |
US20090318380A1 (en) | 2007-11-20 | 2009-12-24 | Pharmasset, Inc. | 2',4'-substituted nucleosides as antiviral agents |
CN102015636B (zh) * | 2008-05-08 | 2014-08-13 | 埃沃特克股份有限公司 | 作为组胺h3受体拮抗剂的氮杂环丁烷类和环丁烷类化合物 |
ES2714852T3 (es) * | 2009-03-18 | 2019-05-30 | Janssen Pharmaceutica Nv | Procedimiento para la preparación de moduladores de receptores H3 de histamina |
CA2774981A1 (en) * | 2009-09-21 | 2011-03-24 | Vanderbilt University | O-benzyl nicotinamide analogs as mglur5 positive allosteric modulators |
BR112014000290B1 (pt) | 2011-07-07 | 2022-05-10 | Gilead Sciences, Inc. | Forma de dosagem oral de combinação de darunavir, processo para preparação de uma forma de dosagem oral e uso de granulado de darunavir |
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GB0324159D0 (en) * | 2003-10-15 | 2003-11-19 | Glaxo Group Ltd | Novel compounds |
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GB0514812D0 (en) | 2005-07-19 | 2005-08-24 | Glaxo Group Ltd | Compounds |
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2008
- 2008-11-17 US US12/272,268 patent/US8883776B2/en not_active Expired - Fee Related
- 2008-11-17 MX MX2010005488A patent/MX2010005488A/es active IP Right Grant
- 2008-11-17 WO PCT/US2008/083764 patent/WO2009067401A1/en active Application Filing
- 2008-11-17 JP JP2010535014A patent/JP5498390B2/ja not_active Expired - Fee Related
- 2008-11-17 AU AU2008326561A patent/AU2008326561B2/en not_active Ceased
- 2008-11-17 NZ NZ584998A patent/NZ584998A/xx not_active IP Right Cessation
- 2008-11-17 UA UAA201007603A patent/UA103468C2/ru unknown
- 2008-11-17 BR BRPI0820481-0A patent/BRPI0820481A2/pt not_active IP Right Cessation
- 2008-11-17 EP EP08852442.6A patent/EP2222664B1/en not_active Not-in-force
- 2008-11-17 CN CN201610094782.9A patent/CN105712977B/zh not_active Expired - Fee Related
- 2008-11-17 MY MYPI2010002288A patent/MY158253A/en unknown
- 2008-11-17 CA CA2706328A patent/CA2706328C/en active Active
- 2008-11-17 KR KR1020107013252A patent/KR101546712B1/ko active IP Right Grant
- 2008-11-17 EA EA201070637A patent/EA018582B1/ru unknown
- 2008-11-17 CN CN200880117055A patent/CN101868454A/zh active Pending
- 2008-11-19 TW TW097144606A patent/TWI491604B/zh not_active IP Right Cessation
- 2008-11-20 CL CL2008003465A patent/CL2008003465A1/es unknown
- 2008-11-20 AR ARP080105055A patent/AR069387A1/es not_active Application Discontinuation
-
2010
- 2010-05-18 NI NI201000086A patent/NI201000086A/es unknown
- 2010-05-19 EC EC2010010190A patent/ECSP10010190A/es unknown
- 2010-05-20 CO CO10060285A patent/CO6210700A2/es active IP Right Grant
- 2010-06-18 ZA ZA2010/04334A patent/ZA201004334B/en unknown
- 2010-06-21 CR CR11529A patent/CR11529A/es not_active Application Discontinuation
-
2011
- 2011-02-28 HK HK11101993.2A patent/HK1147994A1/xx not_active IP Right Cessation
-
2018
- 2018-02-14 AR ARP180100346A patent/AR110977A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
AR069387A1 (es) | 2010-01-20 |
CR11529A (es) | 2012-10-25 |
KR20100098636A (ko) | 2010-09-08 |
WO2009067401A1 (en) | 2009-05-28 |
TWI491604B (zh) | 2015-07-11 |
AR110977A2 (es) | 2019-05-22 |
US20090131415A1 (en) | 2009-05-21 |
CN105712977B (zh) | 2021-06-29 |
CO6210700A2 (es) | 2010-10-20 |
EA201070637A1 (ru) | 2010-12-30 |
CN101868454A (zh) | 2010-10-20 |
EP2222664B1 (en) | 2014-10-29 |
CA2706328C (en) | 2016-04-19 |
KR101546712B1 (ko) | 2015-08-24 |
CL2008003465A1 (es) | 2009-03-06 |
TW200936579A (en) | 2009-09-01 |
BRPI0820481A2 (pt) | 2015-06-16 |
EA018582B1 (ru) | 2013-09-30 |
EP2222664A1 (en) | 2010-09-01 |
ZA201004334B (en) | 2011-10-26 |
ECSP10010190A (es) | 2010-06-29 |
MY158253A (en) | 2016-09-30 |
JP5498390B2 (ja) | 2014-05-21 |
MX2010005488A (es) | 2010-06-01 |
AU2008326561B2 (en) | 2013-12-05 |
US8883776B2 (en) | 2014-11-11 |
CA2706328A1 (en) | 2009-05-28 |
JP2011503233A (ja) | 2011-01-27 |
NZ584998A (en) | 2012-08-31 |
AU2008326561A1 (en) | 2009-05-28 |
CN105712977A (zh) | 2016-06-29 |
HK1147994A1 (en) | 2011-08-26 |
NI201000086A (es) | 2011-03-17 |
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