MX2009012228A - Compuesto de triazolil aminopirimidina. - Google Patents

Compuesto de triazolil aminopirimidina.

Info

Publication number
MX2009012228A
MX2009012228A MX2009012228A MX2009012228A MX2009012228A MX 2009012228 A MX2009012228 A MX 2009012228A MX 2009012228 A MX2009012228 A MX 2009012228A MX 2009012228 A MX2009012228 A MX 2009012228A MX 2009012228 A MX2009012228 A MX 2009012228A
Authority
MX
Mexico
Prior art keywords
aminopyrimidine compounds
triazolyl
triazolyl aminopyrimidine
compounds
cancer
Prior art date
Application number
MX2009012228A
Other languages
English (en)
Inventor
Jason Scott Sawyer
James Robert Henry
Delu Jiang
Hong-Yu Li
Harold Burns Brooks
Joyce Z Crich
Melissa Kate Slater
Hong Hu
William Thomas Mcmillen
Yan Wang
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MX2009012228A publication Critical patent/MX2009012228A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

La presente invención proporciona compuestos de triazolil aminopirimidina útiles en el tratamiento de cáncer.
MX2009012228A 2007-05-16 2008-05-07 Compuesto de triazolil aminopirimidina. MX2009012228A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93834707P 2007-05-16 2007-05-16
PCT/US2008/062808 WO2008144223A2 (en) 2007-05-16 2008-05-07 Triazolyl aminopyrimidine compounds

Publications (1)

Publication Number Publication Date
MX2009012228A true MX2009012228A (es) 2009-12-01

Family

ID=39951591

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009012228A MX2009012228A (es) 2007-05-16 2008-05-07 Compuesto de triazolil aminopirimidina.

Country Status (15)

Country Link
US (1) US8063035B2 (es)
EP (1) EP2155734A2 (es)
JP (1) JP5248600B2 (es)
KR (1) KR101131261B1 (es)
CN (1) CN101679395B (es)
AR (1) AR066473A1 (es)
AU (1) AU2008254319B2 (es)
BR (1) BRPI0811433A2 (es)
CA (1) CA2691997A1 (es)
CL (1) CL2008001323A1 (es)
EA (1) EA016781B1 (es)
MX (1) MX2009012228A (es)
PE (1) PE20090216A1 (es)
TW (1) TW200908981A (es)
WO (1) WO2008144223A2 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7964729B2 (en) 2006-08-28 2011-06-21 Massachusetts Institute Of Technology Sox-based kinase sensor
EP2125793B1 (en) 2006-12-21 2010-09-01 Eli Lilly & Company Imidazolidinonyl aminopyrimidine compounds for the treatment of cancer
BRPI0720607A2 (pt) 2006-12-21 2014-04-08 Lilly Co Eli Compostos de imidazolidinonil aminopirimidina
US8440835B2 (en) 2007-02-26 2013-05-14 Massachusetts Institute Of Technology Environmentally sensitive fluorophores
AR066472A1 (es) 2007-05-16 2009-08-19 Lilly Co Eli Compuesto de triazolil aminopirimidina, composicion farmaceutica que lo comprende y su uso para preparar un medicamento
CA2691997A1 (en) 2007-05-16 2008-11-27 Eli Lilly And Company Triazolyl aminopyrimidine compounds
KR101123178B1 (ko) * 2009-04-09 2012-06-13 (주)에스메디 2-아릴벤조싸이오펜 유도체 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는 퇴행성 뇌질환의 진단 또는 치료용 약학적 조성물
JP2013502901A (ja) * 2009-08-25 2013-01-31 オンコセラピー・サイエンス株式会社 がんの治療および診断の標的遺伝子としてのercc6l
US8409820B2 (en) 2009-08-31 2013-04-02 Massachusetts Institute Of Technology Kinase sensors
UA119247C2 (uk) 2013-09-06 2019-05-27 РОЙВЕНТ САЙЕНСИЗ ҐмбГ Спіроциклічні сполуки як інгібітори триптофангідроксилази
US9611201B2 (en) * 2015-03-05 2017-04-04 Karos Pharmaceuticals, Inc. Processes for preparing (R)-1-(5-chloro-[1,1′-biphenyl]-2-yl)-2,2,2-trifluoroethanol and 1-(5-chloro-[1,1′-biphenyl]-2-yl)-2,2,2-trifluoroethanone
JP7090037B2 (ja) * 2016-06-23 2022-06-23 エフ.ホフマン-ラ ロシュ アーゲー 新規な[1,2,3]トリアゾロ[4,5-d]ピリミジン誘導体
WO2020068600A1 (en) * 2018-09-24 2020-04-02 Rapt Therapeutics, Inc. Ubiquitin-specific-processing protease 7 (usp7) modulators and uses thereof
WO2021042169A1 (en) * 2019-09-05 2021-03-11 The University Of Melbourne Nitrification inhibitors
CN112341428A (zh) * 2020-11-04 2021-02-09 菏泽鸿特药业有限公司 一种噻吩-2-乙胺的生产方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4929726A (en) * 1988-02-09 1990-05-29 Georgia State University Foundation, Inc. Novel diazines and their method of preparation
WO2004063192A1 (en) 2003-01-10 2004-07-29 Pharmacopeia Drug Discovery, Inc. Imidazolyl pyrimidine derivatives useful as il-8 receptor modulators
GB0308466D0 (en) 2003-04-11 2003-05-21 Novartis Ag Organic compounds
US7329764B2 (en) * 2003-07-31 2008-02-12 Boehringer Ingelheim Pharmaceuticals, Inc. Substitute benzothiophene compounds
JP4932735B2 (ja) * 2004-12-17 2012-05-16 アムジエン・インコーポレーテツド アミノピリミジン化合物および使用方法
TW200800201A (en) 2005-11-18 2008-01-01 Lilly Co Eli Pyrimidinyl benzothiophene compounds
EP2001480A4 (en) 2006-03-31 2011-06-15 Abbott Lab Indazole CONNECTIONS
BRPI0720607A2 (pt) * 2006-12-21 2014-04-08 Lilly Co Eli Compostos de imidazolidinonil aminopirimidina
EP2125793B1 (en) 2006-12-21 2010-09-01 Eli Lilly & Company Imidazolidinonyl aminopyrimidine compounds for the treatment of cancer
CA2691997A1 (en) 2007-05-16 2008-11-27 Eli Lilly And Company Triazolyl aminopyrimidine compounds
AR066472A1 (es) * 2007-05-16 2009-08-19 Lilly Co Eli Compuesto de triazolil aminopirimidina, composicion farmaceutica que lo comprende y su uso para preparar un medicamento

Also Published As

Publication number Publication date
AR066473A1 (es) 2009-08-19
JP5248600B2 (ja) 2013-07-31
KR20090130242A (ko) 2009-12-21
US20100087431A1 (en) 2010-04-08
EA200971068A1 (ru) 2010-04-30
WO2008144223A3 (en) 2009-02-05
TW200908981A (en) 2009-03-01
KR101131261B1 (ko) 2012-04-24
EP2155734A2 (en) 2010-02-24
EA016781B1 (ru) 2012-07-30
JP2010527365A (ja) 2010-08-12
US8063035B2 (en) 2011-11-22
AU2008254319A1 (en) 2008-11-27
PE20090216A1 (es) 2009-02-28
AU2008254319B2 (en) 2012-04-19
CL2008001323A1 (es) 2009-05-29
CN101679395A (zh) 2010-03-24
WO2008144223A2 (en) 2008-11-27
CN101679395B (zh) 2012-06-13
BRPI0811433A2 (pt) 2016-03-22
CA2691997A1 (en) 2008-11-27

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