WO2008103431A3 - Dnai - liposomes - Google Patents
Dnai - liposomes Download PDFInfo
- Publication number
- WO2008103431A3 WO2008103431A3 PCT/US2008/002332 US2008002332W WO2008103431A3 WO 2008103431 A3 WO2008103431 A3 WO 2008103431A3 US 2008002332 W US2008002332 W US 2008002332W WO 2008103431 A3 WO2008103431 A3 WO 2008103431A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- dnai
- liposomes
- cancer
- treatment
- methods
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Abstract
The invention provides oligonucleotide compositions and methods for the treatment of cancer.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US90297307P | 2007-02-23 | 2007-02-23 | |
US60/902,973 | 2007-02-23 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2008103431A2 WO2008103431A2 (en) | 2008-08-28 |
WO2008103431A3 true WO2008103431A3 (en) | 2009-06-25 |
Family
ID=39631112
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2008/002332 WO2008103431A2 (en) | 2007-02-23 | 2008-02-21 | Dnai - liposomes |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2008103431A2 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8815599B2 (en) | 2004-06-01 | 2014-08-26 | Pronai Therapeutics, Inc. | Methods and compositions for the inhibition of gene expression |
ES2419106T3 (en) | 2005-12-01 | 2013-08-19 | Pronai Therapeutics, Inc. | Amphoteric liposome formulation |
WO2009051712A1 (en) * | 2007-10-15 | 2009-04-23 | Pronai Therapeutics, Inc. | Dnai amphoteric liposome formulation |
US10100331B2 (en) | 2012-10-29 | 2018-10-16 | Agency For Science, Technology And Research | Reagent for gene-drug therapeutics |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998014172A1 (en) * | 1996-10-04 | 1998-04-09 | Board Of Regents, The University Of Texas System | Inhibition of bcl-2 protein expression by liposomal antisense oligodeoxynucleotides |
WO2003073826A2 (en) * | 2002-03-01 | 2003-09-12 | Sagres Discovery, Inc | Novel compositions and methods for cancer |
US20050181037A1 (en) * | 2002-05-24 | 2005-08-18 | Neopharm, Inc. | Cardiolipin compositions their methods of preparation and use |
WO2007014150A2 (en) * | 2005-07-22 | 2007-02-01 | Neopharm, Inc. | Method of administering liposomes containing oligonucleotides |
WO2007031333A2 (en) * | 2005-09-15 | 2007-03-22 | Novosom Ag | Improvements in or relating to amphoteric liposomes |
WO2007149269A2 (en) * | 2006-06-12 | 2007-12-27 | Oncomethylome Sciences S.A. | Methylation markers for early detection and prognosis of colon cancers |
-
2008
- 2008-02-21 WO PCT/US2008/002332 patent/WO2008103431A2/en active Application Filing
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998014172A1 (en) * | 1996-10-04 | 1998-04-09 | Board Of Regents, The University Of Texas System | Inhibition of bcl-2 protein expression by liposomal antisense oligodeoxynucleotides |
WO2003073826A2 (en) * | 2002-03-01 | 2003-09-12 | Sagres Discovery, Inc | Novel compositions and methods for cancer |
US20050181037A1 (en) * | 2002-05-24 | 2005-08-18 | Neopharm, Inc. | Cardiolipin compositions their methods of preparation and use |
WO2007014150A2 (en) * | 2005-07-22 | 2007-02-01 | Neopharm, Inc. | Method of administering liposomes containing oligonucleotides |
WO2007031333A2 (en) * | 2005-09-15 | 2007-03-22 | Novosom Ag | Improvements in or relating to amphoteric liposomes |
WO2007149269A2 (en) * | 2006-06-12 | 2007-12-27 | Oncomethylome Sciences S.A. | Methylation markers for early detection and prognosis of colon cancers |
Non-Patent Citations (2)
Title |
---|
CHOI W-J ET AL: "Low toxicity of cationic lipid-based emulsion for gene transfer", BIOMATERIALS, ELSEVIER SCIENCE PUBLISHERS BV., BARKING, GB, vol. 25, no. 27, 1 December 2004 (2004-12-01), pages 5893 - 5903, XP004511128, ISSN: 0142-9612 * |
LASIC D D: "Recent developments in medical applications of liposomes: sterically stabilized liposomes in cancer therapy and gene delivery in vivo", JOURNAL OF CONTROLLED RELEASE, ELSEVIER, AMSTERDAM, NL, vol. 48, no. 2-3, 13 October 1997 (1997-10-13), pages 203 - 222, XP004125857, ISSN: 0168-3659 * |
Also Published As
Publication number | Publication date |
---|---|
WO2008103431A2 (en) | 2008-08-28 |
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