TWI430805B - 使用ｆｇｆ２３融合多肽之方法及組合物 - Google Patents

使用ｆｇｆ２３融合多肽之方法及組合物 Download PDF

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TWI430805B
TWI430805B TW100103508A TW100103508A TWI430805B TW I430805 B TWI430805 B TW I430805B TW 100103508 A TW100103508 A TW 100103508A TW 100103508 A TW100103508 A TW 100103508A TW I430805 B TWI430805 B TW I430805B
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polypeptide
seq
klotho
fusion polypeptide
fusion
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TW100103508A
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TW201129373A (en
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大衛 葛萊斯
秀 義 胡
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諾華公司
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TW100103508A 2010-01-29 2011-01-28 使用ｆｇｆ２３融合多肽之方法及組合物 TWI430805B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12/696,693 US8420088B2 (en) 2008-01-28 2010-01-29 Methods and compositions using FGF23 fusion polypeptides

Publications (2)

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TW201129373A TW201129373A (en) 2011-09-01
TWI430805B true TWI430805B (zh) 2014-03-21

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TW103100421A TWI569805B (zh) 2010-01-29 2011-01-28 使用ｆｇｆ２３融合多肽之方法及組合物

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US (3) US8420088B2 (https=)
EP (2) EP2529016B1 (https=)
JP (2) JP5964243B2 (https=)
KR (1) KR20130032296A (https=)
CN (3) CN103204941B (https=)
AR (1) AR080043A1 (https=)
AU (1) AU2011209380B2 (https=)
CA (1) CA2787285A1 (https=)
EA (1) EA201201047A1 (https=)
ES (1) ES2605302T3 (https=)
MX (1) MX336391B (https=)
PL (1) PL2529016T3 (https=)
PT (1) PT2529016T (https=)
TW (2) TWI430805B (https=)
UY (1) UY33204A (https=)
WO (1) WO2011092234A1 (https=)

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TW200936156A (en) 2008-01-28 2009-09-01 Novartis Ag Methods and compositions using Klotho-FGF fusion polypeptides
CN105601748B (zh) 2011-07-01 2021-08-27 恩格姆生物制药公司 用于代谢病症和疾病治疗的组合物、应用和方法
HK1214832A1 (zh) 2012-11-28 2016-08-05 恩格姆生物制药公司 用於代謝病症和疾病治療的組合物和方法
US9290557B2 (en) 2012-11-28 2016-03-22 Ngm Biopharmaceuticals, Inc. Compositions comprising variants and fusions of FGF19 polypeptides
CN102961739A (zh) * 2012-12-12 2013-03-13 黄曙 Klotho蛋白的用途
ES2915851T3 (es) 2012-12-27 2022-06-27 Ngm Biopharmaceuticals Inc Péptidos quiméricos de FGF19 para usar en el tratamiento de trastornos de ácidos biliares
US9273107B2 (en) 2012-12-27 2016-03-01 Ngm Biopharmaceuticals, Inc. Uses and methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases
US20160120959A1 (en) * 2013-03-14 2016-05-05 The Board Of Regents Of The University Of Oklahoma Use of Klotho Nucleic Acids or Proteins for Treatment of Diabetes and Diabetes-Related Conditions
KR101492710B1 (ko) * 2013-04-03 2015-02-13 중앙대학교 산학협력단 Fgf23 유전자를 이용한 전립선암 진단용 마커 및 이를 이용한 전립선암 예측 및 진단 방법
ES2714127T3 (es) * 2013-10-24 2019-05-27 Tokyo Metropolitan Geriatric Hospital And Inst Of Gerontology Células madre musculares o mioblastos, procedimiento de cribado de sustancias que participan en la conversión metabólica usando las mismas, y composición farmacéutica que comprende la sustancia obtenida de dicho procedimiento del cribado
CA2927592C (en) 2013-10-28 2020-08-18 Ngm Biopharmaceuticals, Inc. Fgf-19 variants for treating a fgf-19 dependent cancer or tumor
AU2014348657A1 (en) 2013-11-13 2016-05-19 Novartis Ag mTOR inhibitors for enhancing the immune response
PE20170256A1 (es) 2014-01-24 2017-04-22 Ngm Biopharmaceuticals Inc Proteinas de union y sus metodos de uso
JP6370577B2 (ja) * 2014-03-26 2018-08-08 国立大学法人京都工芸繊維大学 抗老化物質のスクリーニング方法
WO2015183890A2 (en) 2014-05-28 2015-12-03 Ngm Biopharmaceuticals, Inc. Methods and compositions for the treatment of metabolic disorders and diseases
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