TWI329111B - Azepinoindole and pyridoindole derivatives as pharmaceutical agents - Google Patents
Azepinoindole and pyridoindole derivatives as pharmaceutical agents Download PDFInfo
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- TWI329111B TWI329111B TW092114049A TW92114049A TWI329111B TW I329111 B TWI329111 B TW I329111B TW 092114049 A TW092114049 A TW 092114049A TW 92114049 A TW92114049 A TW 92114049A TW I329111 B TWI329111 B TW I329111B
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- optionally substituted
- alkyl
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- aryl
- hydrogen
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- IVCGJOSPVGENCT-UHFFFAOYSA-N 1h-pyrrolo[2,3-f]quinoline Chemical class N1=CC=CC2=C(NC=C3)C3=CC=C21 IVCGJOSPVGENCT-UHFFFAOYSA-N 0.000 title 1
- 239000008177 pharmaceutical agent Substances 0.000 title 1
- ISZIQZCZKOFSBT-UHFFFAOYSA-N pyrrolo[2,3-g][1]benzazepine Chemical compound N1=CC=CC=C2C3=NC=CC3=CC=C21 ISZIQZCZKOFSBT-UHFFFAOYSA-N 0.000 title 1
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- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 39
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Classifications
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- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
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Landscapes
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| US38357402P | 2002-05-24 | 2002-05-24 |
Publications (2)
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| TW092114049A TWI329111B (en) | 2002-05-24 | 2003-05-23 | Azepinoindole and pyridoindole derivatives as pharmaceutical agents |
Country Status (8)
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| JP (2) | JP4646293B2 (enExample) |
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| AU (1) | AU2003243328C1 (enExample) |
| CA (1) | CA2485909C (enExample) |
| TW (1) | TWI329111B (enExample) |
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| DE10252667A1 (de) | 2002-11-11 | 2004-05-27 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
| FR2848452B1 (fr) * | 2002-12-12 | 2007-04-06 | Aventis Pharma Sa | Application des inhibiteurs de recapture intestinale des acides biliaires pour la prevention et le traitement de la maladie d'alzheimer |
| AU2004234405A1 (en) * | 2003-04-29 | 2004-11-11 | Arqule, Inc. | Antibiotic tetrahydro-beta-carboline derivatives |
| US7872133B2 (en) | 2003-06-23 | 2011-01-18 | Ono Pharmaceutical Co., Ltd. | Tricyclic heterocycle compound |
| KR20060052867A (ko) * | 2003-07-23 | 2006-05-19 | 엑셀리시스, 인코포레이티드 | 약제로서의 아제핀 유도체 |
| EA201200555A1 (ru) * | 2004-03-15 | 2013-01-30 | ПиТиСи ТЕРАПЬЮТИКС, ИНК. | Производные карболина, полезные в ингибировании ангиогенеза |
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| WO2008036021A1 (en) * | 2006-09-20 | 2008-03-27 | Astrazeneca Ab | Tetrahydro-lh-pyrido [3,4 -b] indole derivatives as cbl receptor ligands |
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-
2003
- 2003-05-23 TW TW092114049A patent/TWI329111B/zh not_active IP Right Cessation
- 2003-05-27 WO PCT/US2003/016767 patent/WO2003099821A1/en not_active Ceased
- 2003-05-27 AU AU2003243328A patent/AU2003243328C1/en not_active Expired
- 2003-05-27 US US10/447,302 patent/US7485634B2/en not_active Expired - Lifetime
- 2003-05-27 CA CA2485909A patent/CA2485909C/en not_active Expired - Lifetime
- 2003-05-27 EP EP03755523A patent/EP1532153B8/en not_active Expired - Lifetime
- 2003-05-27 JP JP2004507478A patent/JP4646293B2/ja not_active Expired - Fee Related
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2009
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| JP2005531585A (ja) | 2005-10-20 |
| EP1532153B1 (en) | 2012-02-29 |
| JP4646293B2 (ja) | 2011-03-09 |
| AU2003243328B2 (en) | 2010-05-20 |
| EP1532153A1 (en) | 2005-05-25 |
| AU2003243328A1 (en) | 2003-12-12 |
| AU2003243328C1 (en) | 2010-10-21 |
| US20040023947A1 (en) | 2004-02-05 |
| CA2485909C (en) | 2011-02-22 |
| ATE547420T1 (de) | 2012-03-15 |
| US8133992B2 (en) | 2012-03-13 |
| TW200307684A (en) | 2003-12-16 |
| WO2003099821A1 (en) | 2003-12-04 |
| US20090326218A1 (en) | 2009-12-31 |
| EP1532153B8 (en) | 2012-04-11 |
| CA2485909A1 (en) | 2003-12-04 |
| US7485634B2 (en) | 2009-02-03 |
| JP2010229148A (ja) | 2010-10-14 |
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