PL2975028T3 - Związek pirazoloamidowy i jego zastosowania medyczne - Google Patents

Związek pirazoloamidowy i jego zastosowania medyczne

Info

Publication number
PL2975028T3
PL2975028T3 PL14763385T PL14763385T PL2975028T3 PL 2975028 T3 PL2975028 T3 PL 2975028T3 PL 14763385 T PL14763385 T PL 14763385T PL 14763385 T PL14763385 T PL 14763385T PL 2975028 T3 PL2975028 T3 PL 2975028T3
Authority
PL
Poland
Prior art keywords
pyrazole
amide compound
uses therefor
medicinal uses
medicinal
Prior art date
Application number
PL14763385T
Other languages
English (en)
Inventor
Takahisa Motomura
Gakujun SHOMI
Original Assignee
Japan Tobacco, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51536938&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2975028(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Japan Tobacco, Inc. filed Critical Japan Tobacco, Inc.
Publication of PL2975028T3 publication Critical patent/PL2975028T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/23Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/12Ophthalmic agents for cataracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/78Benzoic acid esters

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL14763385T 2013-03-15 2014-03-14 Związek pirazoloamidowy i jego zastosowania medyczne PL2975028T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361791164P 2013-03-15 2013-03-15
JP2013053195 2013-03-15
JP2013127318 2013-06-18
EP14763385.3A EP2975028B1 (en) 2013-03-15 2014-03-14 Pyrazole-amide compound and medicinal uses therefor
PCT/JP2014/056825 WO2014142290A1 (ja) 2013-03-15 2014-03-14 ピラゾール-アミド化合物およびその医薬用途

Publications (1)

Publication Number Publication Date
PL2975028T3 true PL2975028T3 (pl) 2018-10-31

Family

ID=51536938

Family Applications (1)

Application Number Title Priority Date Filing Date
PL14763385T PL2975028T3 (pl) 2013-03-15 2014-03-14 Związek pirazoloamidowy i jego zastosowania medyczne

Country Status (31)

Country Link
US (4) US9040717B2 (pl)
EP (3) EP3805205A1 (pl)
JP (6) JP6208603B2 (pl)
KR (1) KR102226096B1 (pl)
CN (1) CN105051015B (pl)
AU (1) AU2014230569B2 (pl)
BR (1) BR112015022077A2 (pl)
CA (1) CA2904985C (pl)
CL (1) CL2015002608A1 (pl)
CY (1) CY1120173T1 (pl)
DK (1) DK2975028T3 (pl)
ES (1) ES2663789T3 (pl)
HK (1) HK1215808A1 (pl)
HR (1) HRP20180635T1 (pl)
HU (1) HUE036672T2 (pl)
IL (1) IL241355B (pl)
LT (1) LT2975028T (pl)
ME (1) ME03090B (pl)
MX (1) MX2015012743A (pl)
MY (1) MY182884A (pl)
NO (1) NO2975028T3 (pl)
PE (1) PE20151595A1 (pl)
PH (1) PH12015501993B1 (pl)
PL (1) PL2975028T3 (pl)
PT (1) PT2975028T (pl)
RS (1) RS57188B1 (pl)
RU (1) RU2664532C2 (pl)
SG (1) SG11201507327TA (pl)
SI (1) SI2975028T1 (pl)
TW (1) TWI633885B (pl)
WO (1) WO2014142290A1 (pl)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6437452B2 (ja) 2013-01-14 2018-12-12 インサイト・ホールディングス・コーポレイションIncyte Holdings Corporation Pimキナーゼ阻害剤として有用な二環式芳香族カルボキサミド化合物
HUE050215T2 (hu) 2013-01-15 2020-11-30 Incyte Holdings Corp Pim kináz inhibitorokként hasznos tiazolkarboxamid és piridinkarboxamid vegyületek
BR112015022077A2 (pt) * 2013-03-15 2017-07-18 Japan Tobacco Inc composto de pirazol-amida e usos medicinais do mesmo
JP2016528298A (ja) 2013-08-23 2016-09-15 インサイト・コーポレイションIncyte Corporation Pimキナーゼ阻害剤として有用なフロピリジン及びチエノピリジンカルボキシアミド化合物
US9580418B2 (en) 2014-07-14 2017-02-28 Incyte Corporation Bicyclic aromatic carboxamide compounds useful as Pim kinase inhibitors
US9822124B2 (en) 2014-07-14 2017-11-21 Incyte Corporation Bicyclic heteroaromatic carboxamide compounds useful as Pim kinase inhibitors
WO2016196244A1 (en) 2015-05-29 2016-12-08 Incyte Corporation Pyridineamine compounds useful as pim kinase inhibitors
AR105967A1 (es) 2015-09-09 2017-11-29 Incyte Corp Sales de un inhibidor de pim quinasa
TW201718546A (zh) 2015-10-02 2017-06-01 英塞特公司 適用作pim激酶抑制劑之雜環化合物
CA3031621A1 (en) * 2016-07-29 2018-02-01 Japan Tobacco Inc. Production method for pyrazole-amide compound
AR113922A1 (es) 2017-12-08 2020-07-01 Incyte Corp Terapia de combinación de dosis baja para el tratamiento de neoplasias mieloproliferativas
WO2019151274A1 (ja) * 2018-02-01 2019-08-08 日本たばこ産業株式会社 含窒素複素環アミド化合物及びその医薬用途
CN112638377A (zh) * 2018-09-11 2021-04-09 日本烟草产业株式会社 含有吡唑酰胺化合物的慢性肾脏病的治疗或预防剂
WO2020179770A1 (ja) 2019-03-04 2020-09-10 日本たばこ産業株式会社 ピラゾール-アミド化合物の非晶質固体分散体
CA3166747A1 (en) * 2020-03-04 2021-09-10 Japan Tobacco Inc. Fused tricyclic compound and medicinal use thereof
TW202319051A (zh) * 2021-09-01 2023-05-16 日商日本煙草產業股份有限公司 含氮三環性化合物及其醫藥用途
KR20240045387A (ko) * 2022-09-28 2024-04-08 (주)제이디바이오사이언스 신규한 플루오렌 유도체 및 이의 용도

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FR2827285B1 (fr) * 2001-07-10 2003-12-05 Rhodia Chimie Sa Reactif et procede pour la perfluoroalcoylation
TWI329111B (en) 2002-05-24 2010-08-21 X Ceptor Therapeutics Inc Azepinoindole and pyridoindole derivatives as pharmaceutical agents
TW200418825A (en) 2002-12-16 2004-10-01 Hoffmann La Roche Novel (R)-and (S) enantiomers of thiophene hydroxamic acid derivatives
SI1620118T1 (sl) 2003-04-08 2014-11-28 Yeda Research And Development Co., Ltd. Reverzibilna pegilirana zdravila
RU2006107371A (ru) 2004-02-20 2006-09-10 Астеллас Фарма Инк. (Jp) Флуореновые производные
FR2885904B1 (fr) 2005-05-19 2007-07-06 Aventis Pharma Sa Nouveaux derives du fluorene, compositions les contenant et utilisation
RU2007147844A (ru) * 2005-05-23 2009-06-27 Джапан Тобакко Инк. (Jp) Пиразольное соединение и содержащее его терапевтическое средство для лечения сахарного диабета
US7767685B2 (en) * 2006-06-29 2010-08-03 King Pharmaceuticals Research And Development, Inc. Adenosine A2B receptor antagonists
FR2936173B1 (fr) * 2008-09-22 2012-09-21 Snecma Procede pour la fabrication d'une piece en titane avec forgeage initial dans le domaine beta
AR074797A1 (es) 2008-10-10 2011-02-16 Japan Tobacco Inc Compuesto de fluoreno , composiciones farmaceuticas , inhibidores de pdhk y pdhk2 , metodos de tratamiento , usos de los mismos y kit comercial
RU2011147232A (ru) * 2009-04-22 2013-05-27 Астеллас Фарма Инк. Производное карбоновой кислоты
BR112015022077A2 (pt) * 2013-03-15 2017-07-18 Japan Tobacco Inc composto de pirazol-amida e usos medicinais do mesmo
AR095346A1 (es) * 2013-03-15 2015-10-07 Japan Tobacco Inc Compuesto de hidrato de fluoreno y sus cristales
US20150025120A1 (en) 2013-07-01 2015-01-22 Japan Tobacco Inc. Pyrazole-alcohol compounds and pharmaceutical use thereof
US20150018403A1 (en) 2013-07-01 2015-01-15 Japan Tobacco Inc. Fluorene-amide compounds and pharmaceutical use thereof

Also Published As

Publication number Publication date
SI2975028T1 (en) 2018-07-31
RS57188B1 (sr) 2018-07-31
ES2663789T3 (es) 2018-04-17
TWI633885B (zh) 2018-09-01
NO2975028T3 (pl) 2018-07-21
PH12015501993A1 (en) 2016-01-11
IL241355B (en) 2019-03-31
IL241355A0 (en) 2015-11-30
JP2019194197A (ja) 2019-11-07
WO2014142290A1 (ja) 2014-09-18
US20140296315A1 (en) 2014-10-02
DK2975028T3 (en) 2018-03-12
JP2020189855A (ja) 2020-11-26
HUE036672T2 (hu) 2018-07-30
EP2975028A1 (en) 2016-01-20
EP2975028B1 (en) 2018-02-21
CN105051015B (zh) 2018-09-25
PT2975028T (pt) 2018-03-29
SG11201507327TA (en) 2015-10-29
EP2975028A4 (en) 2016-08-17
JP2015024984A (ja) 2015-02-05
MY182884A (en) 2021-02-05
BR112015022077A2 (pt) 2017-07-18
CA2904985A1 (en) 2014-09-18
HRP20180635T1 (hr) 2018-06-01
RU2015144182A (ru) 2017-04-24
JP2022000453A (ja) 2022-01-04
ME03090B (me) 2019-01-20
MX2015012743A (es) 2016-02-19
TW201501711A (zh) 2015-01-16
PE20151595A1 (es) 2015-11-24
RU2015144182A3 (pl) 2018-03-06
HK1215808A1 (zh) 2016-09-15
KR20150131221A (ko) 2015-11-24
US9040717B2 (en) 2015-05-26
JP6208603B2 (ja) 2017-10-04
RU2664532C2 (ru) 2018-08-20
US20180256547A1 (en) 2018-09-13
CY1120173T1 (el) 2018-12-12
JP2018188449A (ja) 2018-11-29
PH12015501993B1 (en) 2016-01-11
EP3348545A1 (en) 2018-07-18
CA2904985C (en) 2021-07-20
US20200163937A1 (en) 2020-05-28
JP2018021061A (ja) 2018-02-08
US20160074364A1 (en) 2016-03-17
AU2014230569A1 (en) 2015-10-08
CN105051015A (zh) 2015-11-11
AU2014230569B2 (en) 2017-11-23
EP3805205A1 (en) 2021-04-14
CL2015002608A1 (es) 2016-03-04
KR102226096B1 (ko) 2021-03-09
LT2975028T (lt) 2018-04-10

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