TW585870B - A composition of A2A adenosine receptor agent for diagnosing coronary artery stenosis - Google Patents
A composition of A2A adenosine receptor agent for diagnosing coronary artery stenosis Download PDFInfo
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- TW585870B TW585870B TW089111546A TW89111546A TW585870B TW 585870 B TW585870 B TW 585870B TW 089111546 A TW089111546 A TW 089111546A TW 89111546 A TW89111546 A TW 89111546A TW 585870 B TW585870 B TW 585870B
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
Landscapes
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- Chemical & Material Sciences (AREA)
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- Optics & Photonics (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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| TW089111546A TW585870B (en) | 1999-06-18 | 2000-06-14 | A composition of A2A adenosine receptor agent for diagnosing coronary artery stenosis |
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| US7427606B2 (en) * | 1999-02-01 | 2008-09-23 | University Of Virginia Patent Foundation | Method to reduce inflammatory response in transplanted tissue |
| USRE47351E1 (en) | 1999-06-22 | 2019-04-16 | Gilead Sciences, Inc. | 2-(N-pyrazolo)adenosines with application as adenosine A2A receptor agonists |
| US6214807B1 (en) * | 1999-06-22 | 2001-04-10 | Cv Therapeutics, Inc. | C-pyrazole 2A A receptor agonists |
| US6403567B1 (en) * | 1999-06-22 | 2002-06-11 | Cv Therapeutics, Inc. | N-pyrazole A2A adenosine receptor agonists |
| AU2001238665A1 (en) * | 2000-02-23 | 2001-09-03 | Cv Therapeutics, Inc. | Method of identifying partial agonists of the a2a receptor |
| US6716444B1 (en) | 2000-09-28 | 2004-04-06 | Advanced Cardiovascular Systems, Inc. | Barriers for polymer-coated implantable medical devices and methods for making the same |
| US6953560B1 (en) | 2000-09-28 | 2005-10-11 | Advanced Cardiovascular Systems, Inc. | Barriers for polymer-coated implantable medical devices and methods for making the same |
| US6663662B2 (en) | 2000-12-28 | 2003-12-16 | Advanced Cardiovascular Systems, Inc. | Diffusion barrier layer for implantable devices |
| US6753071B1 (en) | 2001-09-27 | 2004-06-22 | Advanced Cardiovascular Systems, Inc. | Rate-reducing membrane for release of an agent |
| EP1434782A2 (en) * | 2001-10-01 | 2004-07-07 | University of Virginia Patent Foundation | 2-propynyl adenosine analogs having a2a agonist activity and compositions thereof |
| EP1465634B1 (en) | 2001-12-12 | 2014-10-22 | The Government of the United States of America, as represented by the Secretary Department of Health and Human Services | Methods for using adenosine receptor inhibitors to enhance immune response and inflammation |
| AUPR977701A0 (en) * | 2001-12-28 | 2002-01-24 | Austral Ships Pty Ltd | Seagoing vessels |
| US20030224455A1 (en) * | 2002-05-28 | 2003-12-04 | Mariapia Abbracchio | Method for the diagnosis of heart diseases |
| US20050020915A1 (en) * | 2002-07-29 | 2005-01-27 | Cv Therapeutics, Inc. | Myocardial perfusion imaging methods and compositions |
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| US20040243010A1 (en) * | 2003-03-19 | 2004-12-02 | Zoghbi William A. | Use of BNP during stress testing for the detection and risk stratification of individuals with suspected coronary artery disease |
| TW200519106A (en) | 2003-05-02 | 2005-06-16 | Novartis Ag | Organic compounds |
| US20050033044A1 (en) * | 2003-05-19 | 2005-02-10 | Bristol-Myers Squibb Pharma Company | Methods for preparing 2-alkynyladenosine derivatives |
| GB0401334D0 (en) | 2004-01-21 | 2004-02-25 | Novartis Ag | Organic compounds |
| US20070166227A1 (en) * | 2004-02-10 | 2007-07-19 | Shuang Liu | Crowned dithiocarbamate metal complexes and methods for their use |
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| AU2005267706B2 (en) * | 2004-08-02 | 2011-12-08 | University Of Virginia Patent Foundation | 2-propynyl adenosine analogs with modified 5'-ribose groups having A2A agonist activity |
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- 2000-06-12 DK DK00941335T patent/DK1194440T3/da active
- 2000-06-12 PT PT00941335T patent/PT1194440E/pt unknown
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| MXPA01013213A (es) | 2002-06-04 |
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| NZ516169A (en) | 2004-12-24 |
| JP2003502433A (ja) | 2003-01-21 |
| HUP0202094A3 (en) | 2005-02-28 |
| PT1194440E (pt) | 2005-05-31 |
| DE60018185D1 (de) | 2005-03-24 |
| BR0011725A (pt) | 2002-03-26 |
| KR100683607B1 (ko) | 2007-02-20 |
| ATE289317T1 (de) | 2005-03-15 |
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| CA2375374C (en) | 2010-03-23 |
| KR20020033640A (ko) | 2002-05-07 |
| EP1194440A2 (en) | 2002-04-10 |
| IL146939A (en) | 2006-08-20 |
| US6322771B1 (en) | 2001-11-27 |
| MY126794A (en) | 2006-10-31 |
| AR030151A1 (es) | 2003-08-13 |
| AU5605100A (en) | 2001-01-09 |
| JP4890705B2 (ja) | 2012-03-07 |
| NO322229B1 (no) | 2006-08-28 |
| NO20015974L (no) | 2002-02-14 |
| EP1194440B1 (en) | 2005-02-16 |
| WO2000078774A2 (en) | 2000-12-28 |
| ES2233401T3 (es) | 2005-06-16 |
| HU229005B1 (en) | 2013-07-29 |
| DE60018185T2 (de) | 2005-06-30 |
| ZA200200342B (en) | 2003-04-30 |
| IL146939A0 (en) | 2002-08-14 |
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