KR100683607B1 - 아데노신 수용체 작동제에 의한 약리학적 스트레스의 유도 - Google Patents

아데노신 수용체 작동제에 의한 약리학적 스트레스의 유도 Download PDF

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KR100683607B1
KR100683607B1 KR1020017016107A KR20017016107A KR100683607B1 KR 100683607 B1 KR100683607 B1 KR 100683607B1 KR 1020017016107 A KR1020017016107 A KR 1020017016107A KR 20017016107 A KR20017016107 A KR 20017016107A KR 100683607 B1 KR100683607 B1 KR 100683607B1
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alkyl
amino
composition
imaging
coronary artery
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KR20020033640A (ko
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조엘 엠. 린덴
데이비드 케이. 글로버
조지 에이. 벨러
티모시 맥도날드
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유니버시티 오브 버지니아 페이턴트 파운데이션
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020017016107A 1999-06-18 2000-06-12 아데노신 수용체 작동제에 의한 약리학적 스트레스의 유도 Expired - Fee Related KR100683607B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/336,198 1999-06-18
US09/336,198 US6322771B1 (en) 1999-06-18 1999-06-18 Induction of pharmacological stress with adenosine receptor agonists

Publications (2)

Publication Number Publication Date
KR20020033640A KR20020033640A (ko) 2002-05-07
KR100683607B1 true KR100683607B1 (ko) 2007-02-20

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KR1020017016107A Expired - Fee Related KR100683607B1 (ko) 1999-06-18 2000-06-12 아데노신 수용체 작동제에 의한 약리학적 스트레스의 유도

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US (1) US6322771B1 (https=)
EP (1) EP1194440B1 (https=)
JP (1) JP4890705B2 (https=)
KR (1) KR100683607B1 (https=)
AR (1) AR030151A1 (https=)
AT (1) ATE289317T1 (https=)
AU (1) AU5605100A (https=)
BR (1) BR0011725A (https=)
CA (1) CA2375374C (https=)
DE (1) DE60018185T2 (https=)
DK (1) DK1194440T3 (https=)
ES (1) ES2233401T3 (https=)
HU (1) HU229005B1 (https=)
IL (2) IL146939A0 (https=)
MX (1) MXPA01013213A (https=)
MY (1) MY126794A (https=)
NO (1) NO322229B1 (https=)
NZ (1) NZ516169A (https=)
PT (1) PT1194440E (https=)
TW (1) TW585870B (https=)
WO (1) WO2000078774A2 (https=)
ZA (1) ZA200200342B (https=)

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