TW537898B - Enteric formulations of proanthocyanidin polymer antidiarrheal compositions - Google Patents
Enteric formulations of proanthocyanidin polymer antidiarrheal compositions Download PDFInfo
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- TW537898B TW537898B TW086115262A TW86115262A TW537898B TW 537898 B TW537898 B TW 537898B TW 086115262 A TW086115262 A TW 086115262A TW 86115262 A TW86115262 A TW 86115262A TW 537898 B TW537898 B TW 537898B
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- Prior art keywords
- polymer composition
- proanthocyanidin polymer
- pharmaceutical composition
- diarrhea
- proanthocyanidin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
- C07D311/62—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2 with oxygen atoms directly attached in position 3, e.g. anthocyanidins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
- Pyrane Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73077296A | 1996-10-16 | 1996-10-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW537898B true TW537898B (en) | 2003-06-21 |
Family
ID=24936755
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW086115262A TW537898B (en) | 1996-10-16 | 1997-10-16 | Enteric formulations of proanthocyanidin polymer antidiarrheal compositions |
Country Status (14)
| Country | Link |
|---|---|
| US (5) | US7341744B1 (enExample) |
| EP (3) | EP0935417B1 (enExample) |
| JP (1) | JP4195728B2 (enExample) |
| KR (1) | KR100467532B1 (enExample) |
| AT (1) | ATE430477T1 (enExample) |
| AU (1) | AU4988197A (enExample) |
| CA (1) | CA2269078C (enExample) |
| DE (1) | DE69739394D1 (enExample) |
| DK (1) | DK0935417T3 (enExample) |
| ES (1) | ES2326933T3 (enExample) |
| NZ (1) | NZ335317A (enExample) |
| PT (1) | PT935417E (enExample) |
| TW (1) | TW537898B (enExample) |
| WO (1) | WO1998016111A1 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103536583A (zh) * | 2013-11-01 | 2014-01-29 | 张维芬 | 一种原花青素缓释纳米微球及制备方法和应用 |
| CN111526736A (zh) * | 2017-12-27 | 2020-08-11 | 三得利控股株式会社 | 肠道屏障功能改善用组合物 |
Families Citing this family (64)
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| DE69739394D1 (de) * | 1996-10-16 | 2009-06-18 | Napo Pharmaceuticals Inc | Enteral-formulierungen von proanthocyanidzusammensetzungen gegen diarrhöe |
| WO2000047062A2 (en) * | 1999-02-01 | 2000-08-17 | Shaman Pharmaceuticals, Inc. | Enteric formulations of proanthocyanidin polymer dietary supplements and methods for preparing same |
| CA2363454A1 (en) * | 1999-02-15 | 2000-08-17 | The Nikka Whisky Distilling Co., Ltd. | Use of proanthocyanidin |
| PT1178778E (pt) * | 1999-05-17 | 2006-06-30 | D B F | Granulos que contem uma substancia vegetal e o seu procedimento de preparacao |
| NZ528883A (en) * | 2001-03-28 | 2005-12-23 | Asahi Breweries Ltd | Proteotoxin neutralizer |
| CO5400144A1 (es) * | 2002-03-11 | 2004-05-31 | Novartis Ag | Compuestos organicos |
| GB0321996D0 (en) * | 2003-09-19 | 2003-10-22 | Novartis Nutrition Ag | Organic compounds |
| CA2541578C (en) | 2003-10-10 | 2014-03-25 | Ethypharm | Sustained-release microgranules containing gingko biloba extract and the process for manufacturing these |
| KR100720817B1 (ko) * | 2003-12-26 | 2007-05-21 | (주)아모레퍼시픽 | 식물 추출물을 함유하는 제제 및 그 제조방법 |
| JP2006232752A (ja) * | 2005-02-25 | 2006-09-07 | Tokyo Univ Of Marine Science & Technology | コレステロール及び中性脂肪吸収抑制剤及びこれを含む食品 |
| PT1698630E (pt) | 2005-03-03 | 2014-09-15 | Alfa Wassermann Spa | Novas formas polimorfas de rifaximina, processos para a sua produção e a sua utilização nas preparações medicinais |
| ITBO20050123A1 (it) | 2005-03-07 | 2005-06-06 | Alfa Wassermann Spa | Formulazioni farmaceutiche gastroresistenti contenenti rifaximina |
| US20090076132A1 (en) * | 2005-03-11 | 2009-03-19 | Gary Pekoe | Antiviral compositions and methods of treatment |
| JP5167461B2 (ja) * | 2005-09-16 | 2013-03-21 | 国立医薬品食品衛生研究所長 | 炎症性腸疾患予防剤 |
| US7351853B2 (en) * | 2006-01-23 | 2008-04-01 | Albion Advanced Nutrition | Method of manufacturing a granular mineral composition |
| US20070254050A1 (en) | 2006-05-01 | 2007-11-01 | Quart Barry D | Method for treatment of diarrhea-predominant irritable bowel syndrome |
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| FR2938430B1 (fr) * | 2008-11-14 | 2011-05-20 | Debregeas Et Associes Pharma | Granules a base de plantes |
| PL2403938T3 (pl) * | 2009-03-04 | 2020-09-21 | Liveleaf, Inc. | Sposób i materiał do miejscowo aktywowanego kompleksowania cząsteczek biologicznych |
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| EA023814B1 (ru) * | 2009-08-26 | 2016-07-29 | Гленмарк Фармасьютикалс Лтд. | Способ получения полимерных композиций на основе проантоцианидина для фармацевтических форм |
| US8652534B2 (en) | 2009-10-14 | 2014-02-18 | Berry Pharmaceuticals, LLC | Compositions and methods for treatment of mammalian skin |
| IT1398550B1 (it) | 2010-03-05 | 2013-03-01 | Alfa Wassermann Spa | Formulazioni comprendenti rifaximina utili per ottenere un effetto prolungato nel tempo |
| BR112013010774A2 (pt) * | 2010-10-31 | 2017-03-21 | Napo Pharmaceuticals Inc | "usos de crofelemer no tratamento de diarreia associada ao hiv" |
| WO2012101008A1 (en) | 2011-01-27 | 2012-08-02 | Glenmark Pharmaceuticals Limited | Process for the production of proanthocyanidin polymeric composition |
| US9895341B2 (en) | 2011-04-01 | 2018-02-20 | Ocean Spray Cranberries, Inc. | Inflammation and immunity treatments |
| US9192635B2 (en) | 2011-06-24 | 2015-11-24 | Liveleaf, Inc. | Method of treating damaged mucosal or gastrointestinal tissue by administering a composition comprising a mixture of pomegranate and green tea extracts and releasably bound hydrogen peroxide |
| US8722040B2 (en) | 2011-06-24 | 2014-05-13 | Liveleaf, Inc. | Site-activated binding systems that selectively increase the bioactivity of phenolic compounds at target sites |
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| CA2866260A1 (en) * | 2012-03-13 | 2013-09-19 | Piramal Enterprises Limited | Herbal composition for the treatment of metabolic disorders |
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| WO2016112312A1 (en) * | 2015-01-09 | 2016-07-14 | Jaguar Animal Health | Methods of treating diarrhea in companion animals |
| WO2016138125A1 (en) * | 2015-02-26 | 2016-09-01 | Jaguar Animal Health, Inc. | Methods of treating diarrhea and promoting intestinal health in non-human animals |
| US20180021297A1 (en) * | 2015-02-26 | 2018-01-25 | Jaguar Health, Inc. | Use Of Croton- Or Calophyllum-Derived Proanthocyanidin Polymers Or Botanical Extracts In Combination With Rifaximin For The Treatment Of Diarrhea In Non-Human Animals |
| WO2018022475A1 (en) * | 2016-07-25 | 2018-02-01 | Jaguar Health, Inc | Methods of treating porcine epidemic diarrheal virus in piglets |
| IT201600122310A1 (it) | 2016-12-01 | 2018-06-01 | Sofar Spa | Composizione per uso nella terapia di alterazioni dell'intestino |
| BR112018076609B1 (pt) | 2016-12-15 | 2023-02-14 | Société des Produits Nestlé S.A. | Composição alimentícia para animais de estimação, seus usos, e métodos não terapêutico para modular a quantidade e para medição de uma alteração na quantidade de pelo menos uma dentre bifidobacterium, lactobacillus ou clostridium perfringens |
| JOP20190275A1 (ar) * | 2017-05-31 | 2019-11-27 | Napo Pharmaceuticals Inc | طرق وتركيبات لعلاج اضطراب إسهال خِلقي |
| JOP20190276A1 (ar) | 2017-05-31 | 2019-11-27 | Napo Pharmaceuticals Inc | طرق وتركيبات لعلاج إسهال الحمض الصفراوي، والإسهال المرتبط باستئصال الأمعاء الدقيقة أو إزالة المرارة، ومتلازمة الأمعاء القصيرة |
| KR20200008826A (ko) | 2018-07-17 | 2020-01-29 | 성균관대학교산학협력단 | 대장균을 이용한 단백질가수분해효소 k의 생산 방법 |
| CN109464491B (zh) * | 2018-12-03 | 2022-02-01 | 四川省畜牧科学研究院 | 诃子组合物及其在制备预防和/或治疗腹泻和/或乳房炎的产品中的应用 |
| WO2022115481A1 (en) * | 2020-11-24 | 2022-06-02 | Napo Pharmaceuticals, Inc. | Methods and compositions for treating post-acute infection gastrointestinal disorders |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2377201A1 (fr) * | 1977-01-18 | 1978-08-11 | Fabre Sa Pierre | Composition pharmaceutique a activite anti-inflammatoire et vasculotrope |
| SE446940B (sv) * | 1983-02-16 | 1986-10-20 | Carl Axel Virdalm | Medel for bekempande av sjukdomstillstand i matsmeltningsapparaten innehallande skal eller ytterdelar av ber eller frukter |
| US4698360B1 (en) * | 1985-04-09 | 1997-11-04 | D Investigations Pharmacologiq | Plant extract with a proanthocyanidins content as therapeutic agent having radical scavenger effect and use thereof |
| EP0214317B1 (fr) * | 1985-08-30 | 1988-08-17 | Societe Des Produits Nestle S.A. | Produit diététique à activité dépurative et anti-diarrhéique et son procédé de préparation |
| US5141735A (en) * | 1990-06-18 | 1992-08-25 | Hoffman-La Roche, Inc. | Substituted amino-benzodiazepines having anitviral activity |
| US5211944A (en) * | 1990-10-12 | 1993-05-18 | Shaman Pharmaceuticals, Inc. | Proanthocyanidin polymers having antiviral activity and methods of obtaining same |
| SI9011933A (sl) | 1990-10-15 | 1998-06-30 | TANIN SEVNICA Kemična industrija p.o. | Kostanjev taninski ekstrakt, postopek za njegovo pridobivanje in njegova uporaba |
| US5234922A (en) | 1992-09-28 | 1993-08-10 | University Of Iowa Research Foundation | Use of sulfonylureas and other potassium channel regulators to treat secretory diarrhea |
| US5750496A (en) * | 1996-08-12 | 1998-05-12 | Utah State University | Method of controlling cryptosporidium infectons using protease inhibitors |
| DE69739394D1 (de) | 1996-10-16 | 2009-06-18 | Napo Pharmaceuticals Inc | Enteral-formulierungen von proanthocyanidzusammensetzungen gegen diarrhöe |
-
1997
- 1997-10-14 DE DE69739394T patent/DE69739394D1/de not_active Expired - Lifetime
- 1997-10-14 DK DK97912779T patent/DK0935417T3/da active
- 1997-10-14 CA CA2269078A patent/CA2269078C/en not_active Expired - Lifetime
- 1997-10-14 PT PT97912779T patent/PT935417E/pt unknown
- 1997-10-14 AU AU49881/97A patent/AU4988197A/en not_active Abandoned
- 1997-10-14 JP JP51863298A patent/JP4195728B2/ja not_active Expired - Fee Related
- 1997-10-14 AT AT97912779T patent/ATE430477T1/de active
- 1997-10-14 WO PCT/US1997/018845 patent/WO1998016111A1/en not_active Ceased
- 1997-10-14 ES ES97912779T patent/ES2326933T3/es not_active Expired - Lifetime
- 1997-10-14 EP EP97912779A patent/EP0935417B1/en not_active Expired - Lifetime
- 1997-10-14 NZ NZ335317A patent/NZ335317A/en not_active IP Right Cessation
- 1997-10-14 KR KR10-1999-7003305A patent/KR100467532B1/ko not_active Expired - Lifetime
- 1997-10-14 EP EP09003375A patent/EP2060183A3/en not_active Withdrawn
- 1997-10-14 EP EP10177942A patent/EP2255661A3/en not_active Withdrawn
- 1997-10-16 TW TW086115262A patent/TW537898B/zh not_active IP Right Cessation
-
2000
- 2000-11-14 US US09/712,033 patent/US7341744B1/en not_active Expired - Lifetime
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2004
- 2004-08-17 US US10/919,969 patent/US7323195B2/en not_active Expired - Fee Related
-
2008
- 2008-07-17 US US12/175,131 patent/US8574634B2/en not_active Expired - Fee Related
-
2013
- 2013-09-11 US US14/023,598 patent/US20140011869A1/en not_active Abandoned
-
2014
- 2014-05-13 US US14/276,231 patent/US20140329896A1/en not_active Abandoned
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103536583A (zh) * | 2013-11-01 | 2014-01-29 | 张维芬 | 一种原花青素缓释纳米微球及制备方法和应用 |
| CN103536583B (zh) * | 2013-11-01 | 2015-02-25 | 潍坊医学院 | 一种原花青素缓释纳米微球及制备方法和应用 |
| CN111526736A (zh) * | 2017-12-27 | 2020-08-11 | 三得利控股株式会社 | 肠道屏障功能改善用组合物 |
| CN111526736B (zh) * | 2017-12-27 | 2024-02-23 | 三得利控股株式会社 | 肠道屏障功能改善用组合物 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2255661A2 (en) | 2010-12-01 |
| EP2255661A3 (en) | 2010-12-22 |
| EP2060183A2 (en) | 2009-05-20 |
| EP2060183A3 (en) | 2009-06-03 |
| DK0935417T3 (da) | 2009-08-10 |
| US7341744B1 (en) | 2008-03-11 |
| US8574634B2 (en) | 2013-11-05 |
| CA2269078C (en) | 2012-01-24 |
| ES2326933T3 (es) | 2009-10-21 |
| DE69739394D1 (de) | 2009-06-18 |
| AU4988197A (en) | 1998-05-11 |
| US20050019389A1 (en) | 2005-01-27 |
| KR20000049206A (ko) | 2000-07-25 |
| EP0935417B1 (en) | 2009-05-06 |
| US7323195B2 (en) | 2008-01-29 |
| PT935417E (pt) | 2009-07-17 |
| US20140329896A1 (en) | 2014-11-06 |
| JP4195728B2 (ja) | 2008-12-10 |
| US20140011869A1 (en) | 2014-01-09 |
| EP0935417A4 (en) | 2006-08-30 |
| JP2001524938A (ja) | 2001-12-04 |
| NZ335317A (en) | 2001-02-23 |
| ATE430477T1 (de) | 2009-05-15 |
| EP0935417A1 (en) | 1999-08-18 |
| KR100467532B1 (ko) | 2005-01-24 |
| US20090148397A1 (en) | 2009-06-11 |
| CA2269078A1 (en) | 1998-04-23 |
| WO1998016111A1 (en) | 1998-04-23 |
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