TR200001530T2 - Gastrik asit salgılamasının önlenmesi için heterosiklik bileşimler - Google Patents

Gastrik asit salgılamasının önlenmesi için heterosiklik bileşimler

Info

Publication number
TR200001530T2
TR200001530T2 TR2000/01530T TR200001530T TR200001530T2 TR 200001530 T2 TR200001530 T2 TR 200001530T2 TR 2000/01530 T TR2000/01530 T TR 2000/01530T TR 200001530 T TR200001530 T TR 200001530T TR 200001530 T2 TR200001530 T2 TR 200001530T2
Authority
TR
Turkey
Prior art keywords
gastric acid
acid secretion
prevent gastric
heterocyclic compositions
heterocyclic
Prior art date
Application number
TR2000/01530T
Other languages
English (en)
Turkish (tr)
Inventor
Amin Kostrat
Dahlstr�m Mikael
Nordberg Peter
Starke Ingemar
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of TR200001530T2 publication Critical patent/TR200001530T2/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
TR2000/01530T 1997-11-28 1998-11-18 Gastrik asit salgılamasının önlenmesi için heterosiklik bileşimler TR200001530T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9704404A SE9704404D0 (sv) 1997-11-28 1997-11-28 New compounds

Publications (1)

Publication Number Publication Date
TR200001530T2 true TR200001530T2 (tr) 2000-11-21

Family

ID=20409181

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/01530T TR200001530T2 (tr) 1997-11-28 1998-11-18 Gastrik asit salgılamasının önlenmesi için heterosiklik bileşimler

Country Status (32)

Country Link
US (1) US6518270B1 (enExample)
EP (1) EP1042324B1 (enExample)
JP (1) JP2001525322A (enExample)
KR (1) KR20010032559A (enExample)
CN (1) CN1142933C (enExample)
AR (1) AR016972A1 (enExample)
AT (1) ATE233263T1 (enExample)
AU (1) AU752187C (enExample)
BR (1) BR9814755A (enExample)
CA (1) CA2311798A1 (enExample)
CZ (1) CZ292349B6 (enExample)
DE (1) DE69811735T2 (enExample)
DK (1) DK1042324T3 (enExample)
EE (1) EE04060B1 (enExample)
ES (1) ES2191356T3 (enExample)
HU (1) HUP0100601A3 (enExample)
ID (1) ID24730A (enExample)
IL (1) IL136145A0 (enExample)
IS (1) IS5486A (enExample)
MY (1) MY121032A (enExample)
NO (1) NO315704B1 (enExample)
NZ (1) NZ504355A (enExample)
PL (1) PL340920A1 (enExample)
PT (1) PT1042324E (enExample)
RU (1) RU2241000C2 (enExample)
SE (1) SE9704404D0 (enExample)
SK (1) SK283904B6 (enExample)
TR (1) TR200001530T2 (enExample)
TW (1) TW515798B (enExample)
UA (1) UA70932C2 (enExample)
WO (1) WO1999028322A1 (enExample)
ZA (1) ZA9810468B (enExample)

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IL164703A0 (en) 2002-04-19 2005-12-18 Cellular Genomics Inc ImidazoÄ1,2-AÜpyrazin-8-ylamines method of making and method of use thereof
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WO2004029057A1 (ja) * 2002-09-25 2004-04-08 Sankyo Company, Limited 内臓痛の治療または予防のための医薬組成物
WO2004029058A1 (ja) * 2002-09-25 2004-04-08 Sankyo Company, Limited 血中ガストリン濃度上昇の抑制のための医薬組成物
SI1575951T1 (sl) 2002-12-06 2014-10-30 Debiopharm International Sa Forum "Apres-Demain" Heterociklične spojine, postopki za njihovo izdelavo in njihova uporaba v terapiji
US7160885B2 (en) 2003-02-10 2007-01-09 Cgi Pharmaceuticals, Inc. Certain 6, 8-(heteroaryl or aryl) disubstituted imidazo[1,2-a]pyrazines as modulators of Hsp90 complex activity
AR043002A1 (es) * 2003-02-18 2005-07-13 Altana Pharma Ag Imidazopirazinas 6-substituidos
ATE409485T1 (de) * 2003-03-17 2008-10-15 Affinium Pharm Inc Pharmazeutische zusammensetzungen inhibitoren von fab i und weitere antibiotika enthaltend
WO2005014599A1 (en) 2003-06-04 2005-02-17 Cellular Genomics, Inc. Imidazo[1,2-a]pyrazin-8-ylamines and method of inhibition of bruton’s tyrosine kinase by such compounds
US7393848B2 (en) 2003-06-30 2008-07-01 Cgi Pharmaceuticals, Inc. Certain heterocyclic substituted imidazo[1,2-A]pyrazin-8-ylamines and methods of inhibition of Bruton's tyrosine kinase by such compounds
US7259164B2 (en) 2003-08-11 2007-08-21 Cgi Pharmaceuticals, Inc. Certain substituted imidazo[1,2-a]pyrazines, as modulators of kinase activity
CA2544325A1 (en) 2003-11-03 2005-05-12 Astrazeneca Ab Imidazo [1,2-a] pyridine derivatives for the treatment of silent gastro-esophageal reflux
US8450307B2 (en) * 2004-06-04 2013-05-28 Affinium Pharmaceuticals, Inc. Therapeutic agents, and methods of making and using the same
ATE527258T1 (de) * 2004-07-28 2011-10-15 Takeda Pharmaceutical Pyrroloä2,3-cüpyridinverbindung, verfahren zu deren herstellung und anwendung
EP1776361A1 (en) * 2004-08-02 2007-04-25 Altana Pharma AG 5-substituted 1h-pyrroloý3,2-b¨pyridines
EP1784402B1 (en) * 2004-09-03 2011-08-03 Yuhan Corporation PYRROLO[3,2-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF
JP4989477B2 (ja) * 2004-09-03 2012-08-01 ユーハン・コーポレイション ピロロ［３，２−ｃ］ピリジン誘導体及びその製造方法
MX2007002219A (es) * 2004-09-03 2007-05-04 Yuhan Corp Derivados de pirrolo [3,2-b ] piridina y procesos para su preparacion.
KR100958829B1 (ko) * 2004-09-03 2010-05-25 주식회사유한양행 피롤로[2,3-ｃ]피리딘 유도체 및 그의 제조방법
WO2007024294A2 (en) 2005-05-03 2007-03-01 Cgi Pharmaceuticals, Inc. Certain substituted ureas, as modulators of kinase activity
JP2009507032A (ja) 2005-09-02 2009-02-19 アボット・ラボラトリーズ 新規なイミダゾ系複素環
JP2009518399A (ja) * 2005-12-05 2009-05-07 アフィニウム ファーマシューティカルズ， インク． Ｆａｂｉ阻害剤および抗菌剤としてのヘテロ環アクリルアミド化合物
AR061229A1 (es) 2006-06-06 2008-08-13 Schering Corp Imidazopirazinas como inhibidores de la proteina quinasa
JP5468899B2 (ja) 2006-07-20 2014-04-09 アフィニウム ファーマシューティカルズ， インク． Ｆａｂｉインヒビターとしてのアクリルアミド誘導体
EP3255045A1 (en) * 2007-02-16 2017-12-13 Debiopharm International SA Salts, prodrugs and polymorphs of fab i inhibitors
US20090221612A1 (en) 2008-02-13 2009-09-03 Mitchell Scott A Certain substituted amides, method of making, and method of use thereof
KR101745732B1 (ko) 2008-12-08 2017-06-12 질레드 코네티컷 인코포레이티드 이미다조피라진 ｓｙｋ 억제제
US8450321B2 (en) 2008-12-08 2013-05-28 Gilead Connecticut, Inc. 6-(1H-indazol-6-yl)-N-[4-(morpholin-4-yl)phenyl]imidazo-[1,2-A]pyrazin-8-amine, or a pharmaceutically acceptable salt thereof, as a SYK inhibitor
MX2011006094A (es) 2008-12-08 2011-11-29 Gilead Connecticut Inc Inhibidores de imidazopirazina syk.
BR112012022943A2 (pt) 2010-03-11 2018-06-05 Gilead Connecticut Inc inibidores de syk de imidazopiridnas
MY170437A (en) 2012-06-19 2019-07-31 Debiopharm Int Sa Prodrug derivatives of (e)-n-methyl-n-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide
MX2016001304A (es) 2013-07-30 2016-04-07 Gilead Connecticut Inc Polimorfo de inhibidores de syk.
PT3027171T (pt) 2013-07-30 2020-06-18 Gilead Connecticut Inc Formulação de inibidores da syk
SG11201603050TA (en) 2013-12-04 2016-05-30 Gilead Sciences Inc Methods for treating cancers
GB201321738D0 (en) * 2013-12-09 2014-01-22 Ucb Pharma Sa Therapeutic Agents
TWI735853B (zh) 2013-12-23 2021-08-11 美商克洛諾斯生技有限公司 脾酪胺酸激酶抑制劑
US9290505B2 (en) 2013-12-23 2016-03-22 Gilead Sciences, Inc. Substituted imidazo[1,2-a]pyrazines as Syk inhibitors
MX2017000610A (es) 2014-07-14 2017-04-27 Gilead Sciences Inc Metodos combinados para tratar canceres.
PL3419628T3 (pl) 2016-02-26 2021-05-31 Debiopharm International Sa Lek do leczenia zakażeń stopy cukrzycowej
CN115028640A (zh) 2017-08-25 2022-09-09 吉利德科学公司 Syk抑制剂的多晶型物
HRP20230437T1 (hr) 2019-02-14 2023-07-07 Debiopharm International S.A. Formulacija afabicina, postupak izrade iste
KR20210131372A (ko) 2019-02-22 2021-11-02 크로노스 바이오, 인코포레이티드 Syk 억제제로서의 축합된 피라진의 고체 형태
CN113939306B (zh) 2019-06-14 2024-07-19 德彪药业国际股份公司 用于治疗涉及生物膜的细菌感染的药物及其用途

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US4507294A (en) 1982-03-08 1985-03-26 Schering Corp. Imidazo[1,2-a]pyrazines
DE3269604D1 (en) * 1981-06-26 1986-04-10 Schering Corp Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them
US4725601A (en) 1985-06-04 1988-02-16 Fujisawa Pharmaceutical Co., Ltd. Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers
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US5041442A (en) * 1990-07-31 1991-08-20 Syntex (U.S.A.) Inc. Pyrrolo(1,2-a)pyrazines as inhibitors of gastric acid secretion
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SE9602286D0 (sv) 1996-06-10 1996-06-10 Astra Ab New compounds
SE9700661D0 (sv) 1997-02-25 1997-02-25 Astra Ab New compounds
SE9704404D0 (sv) 1997-11-28 1997-11-28 Astra Ab New compounds

Also Published As

Publication number Publication date
JP2001525322A (ja) 2001-12-11
EE04060B1 (et) 2003-06-16
DE69811735T2 (de) 2003-12-18
BR9814755A (pt) 2000-10-03
AU752187C (en) 2003-09-18
KR20010032559A (ko) 2001-04-25
NO315704B1 (no) 2003-10-13
ZA9810468B (en) 1999-05-21
MY121032A (en) 2005-12-30
NO20002721L (no) 2000-07-28
NZ504355A (en) 2001-12-21
AU1356599A (en) 1999-06-16
HUP0100601A3 (en) 2002-10-28
DE69811735D1 (de) 2003-04-03
IS5486A (is) 2000-05-10
AR016972A1 (es) 2001-08-01
HK1030216A1 (en) 2001-04-27
SK283904B6 (sk) 2004-04-06
AU752187B2 (en) 2002-09-12
SE9704404D0 (sv) 1997-11-28
UA70932C2 (uk) 2004-11-15
ID24730A (id) 2000-08-03
NO20002721D0 (no) 2000-05-26
SK6742000A3 (en) 2001-03-12
IL136145A0 (en) 2001-05-20
CZ292349B6 (cs) 2003-09-17
RU2241000C2 (ru) 2004-11-27
EE200000315A (et) 2001-10-15
CN1284078A (zh) 2001-02-14
EP1042324B1 (en) 2003-02-26
DK1042324T3 (da) 2003-05-05
TW515798B (en) 2003-01-01
PT1042324E (pt) 2003-06-30
CZ20001947A3 (cs) 2000-11-15
WO1999028322A1 (en) 1999-06-10
ATE233263T1 (de) 2003-03-15
EP1042324A1 (en) 2000-10-11
US6518270B1 (en) 2003-02-11
CN1142933C (zh) 2004-03-24
ES2191356T3 (es) 2003-09-01
CA2311798A1 (en) 1999-06-10
PL340920A1 (en) 2001-03-12
HUP0100601A2 (hu) 2001-09-28

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