ATE196134T1 - Substituierte chinolinderivate, und ihre verwendung als inhibitoren der magensekretion - Google Patents

Substituierte chinolinderivate, und ihre verwendung als inhibitoren der magensekretion

Info

Publication number
ATE196134T1
ATE196134T1 AT94919046T AT94919046T ATE196134T1 AT E196134 T1 ATE196134 T1 AT E196134T1 AT 94919046 T AT94919046 T AT 94919046T AT 94919046 T AT94919046 T AT 94919046T AT E196134 T1 ATE196134 T1 AT E196134T1
Authority
AT
Austria
Prior art keywords
pct
quinoline derivatives
gastric secretion
substituted quinoline
secretion inhibitors
Prior art date
Application number
AT94919046T
Other languages
English (en)
Inventor
Carl Ingemar Starke
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9302005A external-priority patent/SE9302005D0/xx
Priority claimed from SE9303970A external-priority patent/SE9303970D0/xx
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE196134T1 publication Critical patent/ATE196134T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
AT94919046T 1993-06-11 1994-06-08 Substituierte chinolinderivate, und ihre verwendung als inhibitoren der magensekretion ATE196134T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9302005A SE9302005D0 (sv) 1993-06-11 1993-06-11 New active compounds
SE9303970A SE9303970D0 (sv) 1993-11-30 1993-11-30 New active compounds
PCT/SE1994/000552 WO1994029274A1 (en) 1993-06-11 1994-06-08 New active compounds

Publications (1)

Publication Number Publication Date
ATE196134T1 true ATE196134T1 (de) 2000-09-15

Family

ID=26661770

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94919046T ATE196134T1 (de) 1993-06-11 1994-06-08 Substituierte chinolinderivate, und ihre verwendung als inhibitoren der magensekretion

Country Status (25)

Country Link
US (1) US5889021A (de)
EP (1) EP0702672B1 (de)
JP (1) JP3623794B2 (de)
CN (1) CN1045955C (de)
AT (1) ATE196134T1 (de)
AU (1) AU680516B2 (de)
BR (1) BR9406772A (de)
CA (1) CA2164875A1 (de)
CZ (1) CZ326095A3 (de)
DE (1) DE69425823T2 (de)
EE (1) EE03123B1 (de)
EG (1) EG20435A (de)
ES (1) ES2150494T3 (de)
FI (1) FI955896A0 (de)
HU (1) HUT75122A (de)
IL (1) IL109685A (de)
IS (1) IS4164A (de)
NO (1) NO305799B1 (de)
NZ (1) NZ267740A (de)
PL (1) PL177766B1 (de)
RU (1) RU2142454C1 (de)
SG (1) SG47820A1 (de)
SK (1) SK154995A3 (de)
TW (1) TW261613B (de)
WO (1) WO1994029274A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5556863A (en) * 1993-06-11 1996-09-17 Astra Aktiebolag Compound for gastric acid secretion inhibition
US6077850A (en) * 1997-04-21 2000-06-20 G.D. Searle & Co. Substituted benzopyran analogs for the treatment of inflammation
AU2002950217A0 (en) 2002-07-16 2002-09-12 Prana Biotechnology Limited 8- Hydroxy Quinoline Derivatives
ES2877799T3 (es) * 2015-12-31 2021-11-17 Shanghai Pharmaceuticals Holding Co Ltd Sal de derivado de quinolina, formas polimórficas de la misma, métodos de preparación de la misma, composición y aplicaciones

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US509804A (en) * 1893-11-28 Hoof-weight
US3470186A (en) * 1967-06-02 1969-09-30 American Cyanamid Co Substituted 4-anilino-3-quinolinecarboxylic acids and esters
US4042702A (en) * 1973-08-16 1977-08-16 Byk Gulden Lomberg Chemische Fabrik Gmbh Halogen pyrazole derivatives, a method for producing these halogen pyrazole derivatives, medicaments containing and methods of using them
LU69428A1 (de) * 1974-02-20 1975-12-09
US4120972A (en) * 1975-02-03 1978-10-17 Smith Kline & French Laboratories Limited Imidazolylmethylthio-ethyl isothiourea compounds
NO760996L (de) * 1975-03-25 1976-09-28 Byk Gulden Lomberg Chem Fab
GB1584378A (en) * 1976-10-14 1981-02-11 Byk Gulden Lomberg Chem Fab (pyrazol-1-yl)-phenylacetic acids processes for their preparation and medicaments containing them
LU78804A1 (de) * 1977-12-30 1979-07-20 Byk Gulden Lomberg Chem Fab N-substituierte w-aminoalkanoyl-w-aminoalkansaeuren,ihre verwendung und verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
US4243678A (en) * 1977-12-30 1981-01-06 Byk Gulden Lomberg Chemische Fabrik Gmbh Acylhydrocarbylaminoalkanoic acids, compositions and uses
YU118379A (en) * 1978-05-24 1983-02-28 Byk Gulden Lomberg Chemischefa Process for preparing phenylaminothiophene acetic acid
US4343804A (en) * 1979-03-26 1982-08-10 A. H. Robins Company, Inc. 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds
NO802326L (no) * 1979-08-03 1981-02-04 Byk Gulden Lomberg Chem Fab Fremgangsmaate ved fremstilling av substituerte tetraazatricyklen
EP0024638A1 (de) * 1979-08-30 1981-03-11 Byk Gulden Lomberg Chemische Fabrik GmbH Substituierte Chinolinonalkancarbonsäuren, ihre Herstellung und sie enthaltende Arzneimittel
EP0025192B1 (de) * 1979-09-07 1983-05-11 Byk Gulden Lomberg Chemische Fabrik GmbH Substituierte Oxirancarbonsäuren, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende Arzneimittel
ES8202780A1 (es) * 1979-10-31 1982-03-01 Byk Gulden Lomberg Chem Fab Procedimiento para la preparacion de acidos oxocarboxilicos sustituidos
US4381301A (en) * 1980-05-07 1983-04-26 Byk Gulden Lomberg Chemische Fabrik Gmbh Substituted tricyclic thieno compounds, their synthesis, their use, their compositions and their medicaments
US4337267A (en) * 1980-08-25 1982-06-29 Byk Gulden Lomberg Chemische Fabrik Gmbh Phenalkoxyalkyl- and phenoxyalkyl-substituted oxiranecarboxylic acids, their use and medicaments containing them
EP0046961B1 (de) * 1980-08-29 1985-02-13 Byk Gulden Lomberg Chemische Fabrik GmbH Epoxi-cycloalkylalkancarbonsäuren, Verfahren zu ihrer Herstellung, ihre Verwendung sowie sie enthaltende Arzneimittel
DE3262922D1 (en) * 1981-02-02 1985-05-15 Byk Gulden Lomberg Chem Fab Tricyclic pyrrols, process for their preparation, their use and compositions containing them
FI80022C (fi) * 1982-07-05 1990-04-10 Otsuka Pharma Co Ltd Foerfarande foer framstaellning av ett nytt, terapeutiskt anvaendbart karbostyrilderivat.
DE3579436D1 (de) * 1984-12-18 1990-10-04 Otsuka Pharma Co Ltd Tetrahydrochinolin- derivate, verfahren zu deren herstellung und diese enthaltende antimagengeschwuerzusammensetzungen.
US5250527A (en) * 1985-10-24 1993-10-05 Smithkline & French Laboratories Limited Pyridyl containing benzimidazoles, compositions and use
GB8621425D0 (en) * 1986-09-05 1986-10-15 Smith Kline French Lab Compounds
GB8717644D0 (en) * 1987-07-24 1987-09-03 Smithkline Beckman Intercredit Compounds
GB8804448D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804447D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804445D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
US5049567A (en) * 1988-02-25 1991-09-17 Smithkline Beckman Intercredit B.V. Substituted 4-aminoquinazoline derivatives and method of use
GB8804446D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804443D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804444D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
CA2011086A1 (en) * 1989-03-17 1990-09-17 Karl-Heinz Geiss 2-alkyl-4-arylmethylaminoquinolines, the use thereof and drugs prepared therefrom
GB8908229D0 (en) * 1989-04-12 1989-05-24 Smithkline Beckman Intercredit Compounds
GB8910722D0 (en) * 1989-05-10 1989-06-28 Smithkline Beckman Intercredit Compounds
DE3917233A1 (de) * 1989-05-26 1990-11-29 Basf Ag 8-substituierte 4-(heterocyclylmethylamino)-chinoline, ihre verwendung und daraus hergestellte arzneimittel
GB8918265D0 (en) * 1989-08-10 1989-09-20 Smithkline Beckman Intercredit Compounds
WO1991014677A1 (fr) * 1990-03-28 1991-10-03 Otsuka Pharmaceutical Co., Ltd. Derive de quinoline, medicament anti-ulcereux contenant ce derive et production de ce derive
WO1992012969A1 (en) * 1991-01-29 1992-08-06 Smithkline Beecham Intercredit B.V. Salts of a 4-amino-3-acyl quinoline derivative and their use as inhibitors of gastric acid secretion
GB9126438D0 (en) * 1991-12-12 1992-02-12 Smithkline Beecham Intercredit New quinoline derivatives

Also Published As

Publication number Publication date
IL109685A (en) 1999-03-12
JP3623794B2 (ja) 2005-02-23
EP0702672B1 (de) 2000-09-06
ES2150494T3 (es) 2000-12-01
FI955896A (fi) 1995-12-08
HUT75122A (en) 1997-04-28
CN1125438A (zh) 1996-06-26
BR9406772A (pt) 1996-02-21
PL311957A1 (en) 1996-03-18
NO954928L (no) 1995-12-05
HU9503529D0 (en) 1996-02-28
RU2142454C1 (ru) 1999-12-10
WO1994029274A1 (en) 1994-12-22
SG47820A1 (en) 1998-04-17
AU7012194A (en) 1995-01-03
EG20435A (en) 1999-04-29
JPH09510951A (ja) 1997-11-04
NO305799B1 (no) 1999-07-26
FI955896A0 (fi) 1995-12-08
IL109685A0 (en) 1994-11-28
EP0702672A1 (de) 1996-03-27
AU680516B2 (en) 1997-07-31
TW261613B (de) 1995-11-01
CN1045955C (zh) 1999-10-27
IS4164A (is) 1994-12-12
NZ267740A (en) 1997-05-26
US5889021A (en) 1999-03-30
SK154995A3 (en) 1996-09-04
CA2164875A1 (en) 1994-12-22
DE69425823T2 (de) 2001-01-18
PL177766B1 (pl) 2000-01-31
NO954928D0 (no) 1995-12-05
EE03123B1 (et) 1998-10-15
CZ326095A3 (en) 1996-05-15
DE69425823D1 (de) 2000-10-12

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties