TR199800726T2 - Bir geli�im hormonunun sekretagogunun poliformik �ekilleri. - Google Patents

Bir geli�im hormonunun sekretagogunun poliformik �ekilleri.

Info

Publication number
TR199800726T2
TR199800726T2 TR1998/00726T TR9800726T TR199800726T2 TR 199800726 T2 TR199800726 T2 TR 199800726T2 TR 1998/00726 T TR1998/00726 T TR 1998/00726T TR 9800726 T TR9800726 T TR 9800726T TR 199800726 T2 TR199800726 T2 TR 199800726T2
Authority
TR
Turkey
Prior art keywords
growth hormone
forms
secretagogue
polyformic
methanesulfonylspiro
Prior art date
Application number
TR1998/00726T
Other languages
English (en)
Turkish (tr)
Inventor
P.Draper Jerome
C.Dubost David
J. Kaufman Michael
A. Mccauley James
L.Vandrilla Jennifer
J.Varsolona Richard
Original Assignee
Merck & Co., Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9603361.8A external-priority patent/GB9603361D0/en
Application filed by Merck & Co., Inc. filed Critical Merck & Co., Inc.
Publication of TR199800726T2 publication Critical patent/TR199800726T2/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
TR1998/00726T 1995-10-27 1996-10-23 Bir geli�im hormonunun sekretagogunun poliformik �ekilleri. TR199800726T2 (xx)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US590095P 1995-10-27 1995-10-27
GBGB9603361.8A GB9603361D0 (en) 1996-02-16 1996-02-16 Polymorphic forms of a growth hormone secretagogue

Publications (1)

Publication Number Publication Date
TR199800726T2 true TR199800726T2 (xx) 1998-08-21

Family

ID=26308741

Family Applications (1)

Application Number Title Priority Date Filing Date
TR1998/00726T TR199800726T2 (xx) 1995-10-27 1996-10-23 Bir geli�im hormonunun sekretagogunun poliformik �ekilleri.

Country Status (22)

Country Link
EP (1) EP1019402A1 (xx)
JP (1) JP3204266B2 (xx)
KR (1) KR19990067098A (xx)
CN (1) CN1067687C (xx)
AU (1) AU707946B2 (xx)
BG (1) BG102476A (xx)
BR (1) BR9611229A (xx)
CA (1) CA2235371A1 (xx)
CO (1) CO4770956A1 (xx)
CZ (1) CZ128098A3 (xx)
EA (1) EA000528B1 (xx)
EE (1) EE9800147A (xx)
HK (1) HK1017894A1 (xx)
HU (1) HUP9902208A3 (xx)
IS (1) IS4721A (xx)
NO (1) NO310556B1 (xx)
NZ (1) NZ321370A (xx)
PL (1) PL327511A1 (xx)
SK (1) SK51398A3 (xx)
TR (1) TR199800726T2 (xx)
WO (1) WO1997015574A1 (xx)
YU (1) YU56696A (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6046333A (en) * 1996-10-25 2000-04-04 Merck & Co., Inc. Convergent process for the preparation of a growth hormone secretagogue
US9119832B2 (en) 2014-02-05 2015-09-01 The Regents Of The University Of California Methods of treating mild brain injury
WO2017075535A1 (en) 2015-10-28 2017-05-04 Oxeia Biopharmaceuticals, Inc. Methods of treating neurodegenerative conditions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK282166B6 (sk) * 1992-12-11 2001-11-06 Merck & Co., Inc. Spiropiperidínové deriváty, spôsob ich výroby a farmaceutický prostriedok s ich obsahom

Also Published As

Publication number Publication date
CO4770956A1 (es) 1999-04-30
AU7468696A (en) 1997-05-15
KR19990067098A (ko) 1999-08-16
HUP9902208A2 (hu) 1999-10-28
EA000528B1 (ru) 1999-10-28
CN1067687C (zh) 2001-06-27
NO981867L (no) 1998-06-29
YU56696A (sh) 1999-09-27
BG102476A (en) 1999-04-30
WO1997015574A1 (en) 1997-05-01
HK1017894A1 (en) 1999-12-03
EA199800335A1 (ru) 1998-12-24
CA2235371A1 (en) 1997-05-01
JP3204266B2 (ja) 2001-09-04
BR9611229A (pt) 1999-05-25
HUP9902208A3 (en) 2001-05-28
NZ321370A (en) 1999-11-29
SK51398A3 (en) 1998-12-02
NO310556B1 (no) 2001-07-23
AU707946B2 (en) 1999-07-22
JPH10512295A (ja) 1998-11-24
IS4721A (is) 1998-04-21
PL327511A1 (en) 1998-12-21
EE9800147A (et) 1998-12-15
MX9803351A (es) 1998-09-30
NO981867D0 (no) 1998-04-24
CN1205703A (zh) 1999-01-20
CZ128098A3 (cs) 1998-09-16
EP1019402A1 (en) 2000-07-19

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