HK1017894A1 - Polymorphic forms of a growth hormone secretagogue - Google Patents

Polymorphic forms of a growth hormone secretagogue

Info

Publication number
HK1017894A1
HK1017894A1 HK99102961A HK99102961A HK1017894A1 HK 1017894 A1 HK1017894 A1 HK 1017894A1 HK 99102961 A HK99102961 A HK 99102961A HK 99102961 A HK99102961 A HK 99102961A HK 1017894 A1 HK1017894 A1 HK 1017894A1
Authority
HK
Hong Kong
Prior art keywords
growth hormone
polymorphic forms
hormone secretagogue
secretagogue
polymorphic
Prior art date
Application number
HK99102961A
Other languages
English (en)
Inventor
Jerome P Draper
David C Dubost
Michael J Kaufman
James A Mccauley
Jennifer L Vandrilla
Richard J Varsolona
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9603361.8A external-priority patent/GB9603361D0/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of HK1017894A1 publication Critical patent/HK1017894A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Fodder In General (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Hydrogenated Pyridines (AREA)
HK99102961A 1995-10-27 1999-07-12 Polymorphic forms of a growth hormone secretagogue HK1017894A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US590095P 1995-10-27 1995-10-27
GBGB9603361.8A GB9603361D0 (en) 1996-02-16 1996-02-16 Polymorphic forms of a growth hormone secretagogue
PCT/US1996/016955 WO1997015574A1 (en) 1995-10-27 1996-10-23 Polymorphic forms of a growth hormone secretagogue

Publications (1)

Publication Number Publication Date
HK1017894A1 true HK1017894A1 (en) 1999-12-03

Family

ID=26308741

Family Applications (1)

Application Number Title Priority Date Filing Date
HK99102961A HK1017894A1 (en) 1995-10-27 1999-07-12 Polymorphic forms of a growth hormone secretagogue

Country Status (22)

Country Link
EP (1) EP1019402A1 (xx)
JP (1) JP3204266B2 (xx)
KR (1) KR19990067098A (xx)
CN (1) CN1067687C (xx)
AU (1) AU707946B2 (xx)
BG (1) BG102476A (xx)
BR (1) BR9611229A (xx)
CA (1) CA2235371A1 (xx)
CO (1) CO4770956A1 (xx)
CZ (1) CZ128098A3 (xx)
EA (1) EA000528B1 (xx)
EE (1) EE9800147A (xx)
HK (1) HK1017894A1 (xx)
HU (1) HUP9902208A3 (xx)
IS (1) IS4721A (xx)
NO (1) NO310556B1 (xx)
NZ (1) NZ321370A (xx)
PL (1) PL327511A1 (xx)
SK (1) SK51398A3 (xx)
TR (1) TR199800726T2 (xx)
WO (1) WO1997015574A1 (xx)
YU (1) YU56696A (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6046333A (en) * 1996-10-25 2000-04-04 Merck & Co., Inc. Convergent process for the preparation of a growth hormone secretagogue
US9119832B2 (en) 2014-02-05 2015-09-01 The Regents Of The University Of California Methods of treating mild brain injury
WO2017075535A1 (en) 2015-10-28 2017-05-04 Oxeia Biopharmaceuticals, Inc. Methods of treating neurodegenerative conditions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ151495A3 (en) * 1992-12-11 1995-12-13 Merck & Co Inc Spiropiperidine derivatives, process of their preparation and a pharmaceutical composition containing thereof

Also Published As

Publication number Publication date
CZ128098A3 (cs) 1998-09-16
EA000528B1 (ru) 1999-10-28
JP3204266B2 (ja) 2001-09-04
SK51398A3 (en) 1998-12-02
JPH10512295A (ja) 1998-11-24
CO4770956A1 (es) 1999-04-30
EP1019402A1 (en) 2000-07-19
YU56696A (sh) 1999-09-27
CN1205703A (zh) 1999-01-20
NO981867D0 (no) 1998-04-24
NO310556B1 (no) 2001-07-23
MX9803351A (es) 1998-09-30
AU7468696A (en) 1997-05-15
CN1067687C (zh) 2001-06-27
WO1997015574A1 (en) 1997-05-01
EE9800147A (et) 1998-12-15
KR19990067098A (ko) 1999-08-16
NZ321370A (en) 1999-11-29
CA2235371A1 (en) 1997-05-01
EA199800335A1 (ru) 1998-12-24
BG102476A (en) 1999-04-30
BR9611229A (pt) 1999-05-25
HUP9902208A3 (en) 2001-05-28
NO981867L (no) 1998-06-29
AU707946B2 (en) 1999-07-22
PL327511A1 (en) 1998-12-21
TR199800726T2 (xx) 1998-08-21
HUP9902208A2 (hu) 1999-10-28
IS4721A (is) 1998-04-21

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Legal Events

Date Code Title Description
PF Patent in force