TNSN98002A1 - Forme posologique pharmaceutique a liberation rapide, et gout masque, et procede pour sa preparation. - Google Patents

Forme posologique pharmaceutique a liberation rapide, et gout masque, et procede pour sa preparation.

Info

Publication number
TNSN98002A1
TNSN98002A1 TNTNSN98002A TNSN98002A TNSN98002A1 TN SN98002 A1 TNSN98002 A1 TN SN98002A1 TN TNSN98002 A TNTNSN98002 A TN TNSN98002A TN SN98002 A TNSN98002 A TN SN98002A TN SN98002 A1 TNSN98002 A1 TN SN98002A1
Authority
TN
Tunisia
Prior art keywords
dosage form
pharmaceutical dosage
preparing
same
release pharmaceutical
Prior art date
Application number
TNTNSN98002A
Other languages
English (en)
Inventor
Itoh Akinori
Niwa Toshiyuki
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of TNSN98002A1 publication Critical patent/TNSN98002A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

UNE INVENTION CONCERNE UNE FORME POSOLOGIQUE PHARMACEUTIQUE A LIBERATION RAPIDE ET GOUT MASQUEE. ELLE COMPREND UN NOYAU CONTENANT UN INGREDIENT PHARMACEUTIQUEMENT ACTIF, DE L’HYDROXYPROPYLECELLULOSE A BAS TAUX DE SUBSTITUTION ET DE LA CELLULOSE MICROCRISTALLINE, UNE COUCHE INTERIEURE D’ENROBAGE CONTENANT UN POLYMERE HYDRO SOLUBLE ET UNE COUCHE EXTERIEURE D’ENROBAGE CONTENANT UN POLYMERE INSOLUBLE DANS LA SALIVE. UN PROCEDE POUR SA PREPARATION EST DECRIT. APPLICATION : UTILISATION PAR ADMINISTRATION ORALE POUR MASQUER UN GOUT AMER, AVEC UNE LIBERATION AMELIOREE DU MEDICAMENT DANS LE TRACTUS GASTRO-INTESTINAL
TNTNSN98002A 1997-01-06 1998-01-05 Forme posologique pharmaceutique a liberation rapide, et gout masque, et procede pour sa preparation. TNSN98002A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IB9700003 1997-01-06

Publications (1)

Publication Number Publication Date
TNSN98002A1 true TNSN98002A1 (fr) 2005-03-15

Family

ID=11004515

Family Applications (1)

Application Number Title Priority Date Filing Date
TNTNSN98002A TNSN98002A1 (fr) 1997-01-06 1998-01-05 Forme posologique pharmaceutique a liberation rapide, et gout masque, et procede pour sa preparation.

Country Status (36)

Country Link
EP (1) EP0941075B1 (fr)
JP (1) JP3350059B2 (fr)
KR (1) KR20000069899A (fr)
CN (1) CN1244119A (fr)
AP (1) AP802A (fr)
AR (1) AR008553A1 (fr)
AT (1) ATE238776T1 (fr)
AU (1) AU715867B2 (fr)
BG (1) BG103541A (fr)
BR (1) BR9714253A (fr)
CA (1) CA2277017C (fr)
CO (1) CO4650099A1 (fr)
DE (1) DE69721559T2 (fr)
DK (1) DK0941075T3 (fr)
EA (1) EA199900521A1 (fr)
ES (1) ES2192265T3 (fr)
HN (1) HN1997000151A (fr)
HR (1) HRP980005A2 (fr)
HU (1) HUP0002744A3 (fr)
ID (1) ID21806A (fr)
IL (1) IL130582A0 (fr)
IS (1) IS5095A (fr)
MA (1) MA26464A1 (fr)
NO (1) NO993315D0 (fr)
NZ (1) NZ336251A (fr)
OA (1) OA11072A (fr)
PA (1) PA8443301A1 (fr)
PE (1) PE27999A1 (fr)
PL (1) PL334439A1 (fr)
SK (1) SK89599A3 (fr)
TN (1) TNSN98002A1 (fr)
TR (1) TR199901564T2 (fr)
UY (1) UY24835A1 (fr)
WO (1) WO1998030209A1 (fr)
YU (1) YU31599A (fr)
ZA (1) ZA9829B (fr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6200591B1 (en) * 1998-06-25 2001-03-13 Anwar A. Hussain Method of administration of sildenafil to produce instantaneous response for the treatment of erectile dysfunction
DE19834506A1 (de) * 1998-07-31 2000-02-03 Hexal Ag Transmucosales therapeutisches System zur Anwendung von Sildenafil
DE19834507A1 (de) * 1998-07-31 2000-02-03 Hexal Ag Pharmazeutische, wasserlösliche Tablettenformulierung zur Anwendung von Sildenafil
UA67802C2 (uk) 1998-10-23 2004-07-15 Пфайзер Рісьоч Енд Дівелепмент Компані, Н.В./С.А. Фармацевтична композиція з контрольованим вивільненням інгібітора цгмф фде-5 (варіанти), спосіб її одержання та спосіб лікування еректильної дисфункції
WO2000030617A1 (fr) * 1998-11-25 2000-06-02 Cima Labs Inc. Systeme d'enrobage a liberation rapide masquant le gout
FR2795962B1 (fr) * 1999-07-08 2003-05-09 Prographarm Laboratoires Procede de fabrication de granules enrobes a gout masque et liberation immediate du principe actif
KR100610131B1 (ko) 2000-09-06 2006-08-09 다나베 세이야꾸 가부시키가이샤 경구 투여용 제제
GB0102342D0 (en) * 2001-01-30 2001-03-14 Smithkline Beecham Plc Pharmaceutical formulation
AR034813A1 (es) * 2001-07-20 2004-03-17 Novartis Ag Composiciones farmaceuticas y uso de las mismas
SE0202365D0 (sv) * 2002-08-05 2002-08-05 Pharmacia Ab New formulation and use thereof
CA2561167C (fr) 2004-03-25 2012-09-11 Astellas Pharma Inc. Composition pour la preparation pharmaceutique solide de solifenacine ou des sels de cette derniere
BG66010B1 (bg) * 2004-12-08 2010-10-29 "Софарма" Ад Лекарствена форма на силденафил
CA2593016C (fr) * 2005-01-06 2012-05-15 Cima Labs Inc. Systeme de masquage de gout pour des medicaments non plastifiants
CA2616012A1 (fr) * 2005-07-20 2007-01-25 Astellas Pharma Inc. Particule fine enrobee contenant un medicament pour une preparation se desagregeant dans la bouche et procede de production de celle-ci
US7815939B2 (en) 2005-07-20 2010-10-19 Astellas Pharma Inc. Coated fine particles containing drug for intrabuccally fast disintegrating dosage forms
JP2007031407A (ja) 2005-07-29 2007-02-08 Shin Etsu Chem Co Ltd 低置換度セルロースエーテル含有コーティング用組成物及び不快な味が隠蔽されたフィルムコーティング製剤
US20070098746A1 (en) * 2005-11-02 2007-05-03 Nichols William M Multi-layered coating technology for taste masking
JP4602949B2 (ja) * 2006-08-02 2010-12-22 和光堂株式会社 被覆粒子含有組成物及びその製造方法
KR20090086433A (ko) * 2006-11-14 2009-08-12 선스타 가부시키가이샤 수용성 물질로 표면-처리된 미세결정 셀룰로오즈를 함유하는 구강 위생용 조성물
JP5777273B2 (ja) * 2008-07-10 2015-09-09 大正製薬株式会社 不快な呈味を有する薬物を含有する製剤粒子
WO2010038691A1 (fr) * 2008-09-30 2010-04-08 アステラス製薬株式会社 Composition pharmaceutique particulaire destinée à être administrée oralement
US20110244050A1 (en) 2008-12-12 2011-10-06 Siegfried Rhein S.A. De C.V. Pulsed-release sildenafil composition and method for preparing said composition
DE102009016584A1 (de) 2009-04-06 2010-10-07 Ratiopharm Gmbh Schmelztablette, enthaltend ein Sildenafil-Salz
WO2011081199A1 (fr) * 2009-12-28 2011-07-07 ニプロ株式会社 Préparation à usage oral améliorée en qualité
JP5226732B2 (ja) * 2010-05-20 2013-07-03 エスエス製薬株式会社 催眠用圧縮成型製剤
TWI462739B (zh) * 2010-11-02 2014-12-01 Univ Kaohsiung Medical Ｓｉｌｄｅｎａｆｉｌ－同族物四級銨哌嗪鹽類之製備及醫療用途
GB201119985D0 (en) * 2011-11-19 2012-01-04 Diurnal Ltd Treatment of adrenal insufficiency
CN103271940B (zh) * 2013-05-03 2014-03-12 湖北新济药业有限公司 复方金属离子补充剂及其制备方法
WO2017146052A1 (fr) * 2016-02-23 2017-08-31 ニプロ株式会社 Particules de composition pharmaceutique, préparation se délitant par voie orale comprenant celles-ci, et procédé de production desdites particules de composition pharmaceutique
US20210196635A1 (en) * 2018-08-28 2021-07-01 Towa Pharmaceutical Co., Ltd. Drug-containing particle
CN113559070B (zh) * 2021-08-18 2022-12-06 广州中冠动物药业有限公司 一种适用于宠物咳嗽的药物制备方法
CN116139088B (zh) * 2023-01-31 2024-04-16 南京海纳医药科技股份有限公司 一种含有枸橼酸西地那非的干混悬剂及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63258809A (ja) * 1987-04-16 1988-10-26 Towa Yakuhin Kk 医薬活性成分の放出性にすぐれ、かつ苦味を隠蔽した細粒剤
EP0458751A1 (fr) * 1990-05-25 1991-11-27 Warner-Lambert Company Système à libération d'amino-acides cycliques avec gôut, texture et compressibilité améliorés
JP2576927B2 (ja) * 1992-05-15 1997-01-29 ファイザー製薬株式会社 細粒核
EP1078628B1 (fr) * 1994-07-08 2008-11-19 AstraZeneca AB Forme posologique sous forme de comprimé composite

Also Published As

Publication number Publication date
HN1997000151A (es) 1997-12-20
HUP0002744A3 (en) 2001-01-29
ATE238776T1 (de) 2003-05-15
KR20000069899A (ko) 2000-11-25
PE27999A1 (es) 1999-03-12
AP9801173A0 (en) 1998-01-31
PA8443301A1 (es) 2000-05-24
BG103541A (en) 2000-03-31
NO993315L (no) 1999-07-05
JP3350059B2 (ja) 2002-11-25
AP802A (en) 2000-01-21
HRP980005A2 (en) 1998-10-31
EP0941075A1 (fr) 1999-09-15
NO993315D0 (no) 1999-07-05
ZA9829B (en) 1999-07-05
DK0941075T3 (da) 2003-07-14
AU4880897A (en) 1998-08-03
DE69721559T2 (de) 2003-11-27
IL130582A0 (en) 2000-06-01
OA11072A (en) 2002-02-27
DE69721559D1 (de) 2003-06-05
CN1244119A (zh) 2000-02-09
BR9714253A (pt) 2000-04-18
WO1998030209A1 (fr) 1998-07-16
CA2277017A1 (fr) 1998-07-16
JP2000514830A (ja) 2000-11-07
IS5095A (is) 1999-06-25
CO4650099A1 (es) 1998-09-03
HUP0002744A2 (hu) 2000-12-28
TR199901564T2 (xx) 1999-09-21
UY24835A1 (es) 2000-09-29
EA199900521A1 (ru) 1999-12-29
AU715867B2 (en) 2000-02-10
ID21806A (id) 1999-07-29
NZ336251A (en) 2001-01-26
EP0941075B1 (fr) 2003-05-02
PL334439A1 (en) 2000-02-28
AR008553A1 (es) 2000-01-19
ES2192265T3 (es) 2003-10-01
MA26464A1 (fr) 2004-12-20
CA2277017C (fr) 2002-11-26
YU31599A (sh) 2000-03-21
SK89599A3 (en) 2000-12-11

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