TNSN04028A1 - Cristaux comprenant un sel d'acide malique de n-[2-(diethylamino)ethyl]-5-[(5-fluoro-1,2-dihydro-2-oxo-3h-indole-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide, procedes pour leur preparation et compositions les contenant. - Google Patents

Cristaux comprenant un sel d'acide malique de n-[2-(diethylamino)ethyl]-5-[(5-fluoro-1,2-dihydro-2-oxo-3h-indole-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide, procedes pour leur preparation et compositions les contenant.

Info

Publication number
TNSN04028A1
TNSN04028A1 TNP2004000028A TNSN04028A TNSN04028A1 TN SN04028 A1 TNSN04028 A1 TN SN04028A1 TN P2004000028 A TNP2004000028 A TN P2004000028A TN SN04028 A TNSN04028 A TN SN04028A TN SN04028 A1 TNSN04028 A1 TN SN04028A1
Authority
TN
Tunisia
Prior art keywords
crystals
ylidene
carboxamide
diethylamino
indole
Prior art date
Application number
TNP2004000028A
Other languages
English (en)
French (fr)
Inventor
Michael Hawley
Thomas J Fleck
Stephen P Prescott
Mark T Maloney
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23211067&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TNSN04028(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of TNSN04028A1 publication Critical patent/TNSN04028A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
TNP2004000028A 2001-08-15 2004-02-12 Cristaux comprenant un sel d'acide malique de n-[2-(diethylamino)ethyl]-5-[(5-fluoro-1,2-dihydro-2-oxo-3h-indole-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide, procedes pour leur preparation et compositions les contenant. TNSN04028A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31235301P 2001-08-15 2001-08-15
PCT/US2002/025649 WO2003016305A1 (en) 2001-08-15 2002-08-13 Crystals including a malic acid salt of n-[2-(diethylamino) ethyl]-5-[(5-fluoro-2-oxo-3h-indole-3-ylidene) methyl]-2, 4-dimethyl-1h-pyrrole-3-carboxamide, processes for its preparation and compositions thereof

Publications (1)

Publication Number Publication Date
TNSN04028A1 true TNSN04028A1 (fr) 2006-06-01

Family

ID=23211067

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP2004000028A TNSN04028A1 (fr) 2001-08-15 2004-02-12 Cristaux comprenant un sel d'acide malique de n-[2-(diethylamino)ethyl]-5-[(5-fluoro-1,2-dihydro-2-oxo-3h-indole-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide, procedes pour leur preparation et compositions les contenant.

Country Status (42)

Country Link
US (2) US20030069298A1 (enExample)
EP (3) EP3168218B1 (enExample)
JP (1) JP4159988B2 (enExample)
KR (1) KR100639281B1 (enExample)
CN (2) CN100364991C (enExample)
AP (1) AP1660A (enExample)
AR (1) AR036261A1 (enExample)
AU (1) AU2002324684B2 (enExample)
BG (1) BG108553A (enExample)
BR (1) BR0211612A (enExample)
CA (1) CA2455050C (enExample)
CO (1) CO5550431A2 (enExample)
CU (1) CU23713B7 (enExample)
CY (1) CY1121552T1 (enExample)
CZ (1) CZ2004196A3 (enExample)
DK (2) DK1419151T3 (enExample)
EA (1) EA006445B9 (enExample)
EC (1) ECSP044975A (enExample)
ES (3) ES2453164T3 (enExample)
GE (1) GEP20063777B (enExample)
HR (1) HRP20040112B1 (enExample)
HU (1) HU229206B1 (enExample)
IL (1) IL160097A0 (enExample)
IS (1) IS7147A (enExample)
MA (1) MA27058A1 (enExample)
ME (1) ME00414B (enExample)
MX (1) MXPA04001452A (enExample)
MY (1) MY139383A (enExample)
NO (1) NO326508B1 (enExample)
NZ (1) NZ531232A (enExample)
OA (1) OA12650A (enExample)
PL (1) PL216524B1 (enExample)
PT (2) PT1419151E (enExample)
RS (1) RS53251B (enExample)
SI (2) SI1419151T1 (enExample)
SK (1) SK902004A3 (enExample)
TN (1) TNSN04028A1 (enExample)
TR (1) TR201900509T4 (enExample)
TW (1) TWI269796B (enExample)
UA (1) UA76483C2 (enExample)
WO (1) WO2003016305A1 (enExample)
ZA (1) ZA200400706B (enExample)

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Also Published As

Publication number Publication date
ZA200400706B (en) 2005-05-25
BG108553A (bg) 2005-04-30
RS53251B (sr) 2014-08-29
NO326508B1 (no) 2008-12-15
OA12650A (en) 2006-06-19
EP3168218B1 (en) 2018-11-14
HU229206B1 (en) 2013-09-30
UA76483C2 (en) 2006-08-15
KR100639281B1 (ko) 2006-10-31
TR201900509T4 (tr) 2019-02-21
EP1419151B1 (en) 2014-02-26
PT3168218T (pt) 2019-01-11
MY139383A (en) 2009-09-30
US7435832B2 (en) 2008-10-14
AP1660A (en) 2006-09-09
JP4159988B2 (ja) 2008-10-01
ECSP044975A (es) 2004-03-23
HUP0700036A2 (en) 2008-10-28
PT1419151E (pt) 2014-03-27
AR036261A1 (es) 2004-08-25
IL160097A0 (en) 2004-06-20
CN100364991C (zh) 2008-01-30
CY1121552T1 (el) 2020-05-29
SI3168218T1 (sl) 2019-05-31
EA006445B1 (ru) 2005-12-29
ES2705063T3 (es) 2019-03-21
EP3168218A1 (en) 2017-05-17
PL216524B1 (pl) 2014-04-30
EP2332934B1 (en) 2017-03-01
SI1419151T1 (sl) 2014-04-30
DK1419151T3 (da) 2014-03-31
SK902004A3 (sk) 2005-03-04
HK1088008A1 (zh) 2006-10-27
CN100439360C (zh) 2008-12-03
RS10304A (sr) 2007-02-05
CU20040029A7 (es) 2008-03-14
IS7147A (is) 2004-02-10
CO5550431A2 (es) 2005-08-31
ES2623094T3 (es) 2017-07-10
GEP20063777B (en) 2006-03-27
WO2003016305A1 (en) 2003-02-27
ME00414B (me) 2011-10-10
HK1066542A1 (en) 2005-03-24
MXPA04001452A (es) 2004-05-20
AU2002324684B2 (en) 2006-10-05
EP2332934A1 (en) 2011-06-15
HRP20040112B1 (en) 2012-03-31
PL368317A1 (en) 2005-03-21
KR20040030074A (ko) 2004-04-08
CN1543462A (zh) 2004-11-03
MA27058A1 (fr) 2004-12-20
NZ531232A (en) 2004-11-26
CN1789264A (zh) 2006-06-21
CA2455050C (en) 2007-02-20
JP2005503386A (ja) 2005-02-03
EA006445B9 (ru) 2017-02-28
CZ2004196A3 (cs) 2005-01-12
ES2453164T3 (es) 2014-04-04
EP1419151A1 (en) 2004-05-19
EA200400183A1 (ru) 2004-08-26
TWI269796B (en) 2007-01-01
CA2455050A1 (en) 2003-02-27
US20030069298A1 (en) 2003-04-10
DK3168218T3 (en) 2019-01-14
AP2004002976A0 (en) 2004-03-31
HRP20040112A2 (en) 2004-06-30
US20070191458A1 (en) 2007-08-16
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BR0211612A (pt) 2004-08-24
CU23713B7 (es) 2011-10-05

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