GEP20063777B - Crystals Including Malic Acid Salt of N-[2-(Diethylamino) Ethyl]-5-[(5-Fluoro-2-Oxo-3h-Indole-3-Ylidene) Methyl]-2, 4-Dimethyl-1h-Pyrrole-3-Carboxamide, Processes for Its Preparation and Compositions Thereof - Google Patents

Crystals Including Malic Acid Salt of N-[2-(Diethylamino) Ethyl]-5-[(5-Fluoro-2-Oxo-3h-Indole-3-Ylidene) Methyl]-2, 4-Dimethyl-1h-Pyrrole-3-Carboxamide, Processes for Its Preparation and Compositions Thereof

Info

Publication number
GEP20063777B
GEP20063777B GE5446A GEAP2002005446A GEP20063777B GE P20063777 B GEP20063777 B GE P20063777B GE 5446 A GE5446 A GE 5446A GE AP2002005446 A GEAP2002005446 A GE AP2002005446A GE P20063777 B GEP20063777 B GE P20063777B
Authority
GE
Georgia
Prior art keywords
ylidene
carboxamide
diethylamino
pyrrole
oxo
Prior art date
Application number
GE5446A
Other languages
English (en)
Inventor
Michael Hawley
Thomas J Fleck
Stephen P Prescot
Mark T Maloney
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23211067&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GEP20063777(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of GEP20063777B publication Critical patent/GEP20063777B/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
GE5446A 2001-08-15 2002-08-13 Crystals Including Malic Acid Salt of N-[2-(Diethylamino) Ethyl]-5-[(5-Fluoro-2-Oxo-3h-Indole-3-Ylidene) Methyl]-2, 4-Dimethyl-1h-Pyrrole-3-Carboxamide, Processes for Its Preparation and Compositions Thereof GEP20063777B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31235301P 2001-08-15 2001-08-15

Publications (1)

Publication Number Publication Date
GEP20063777B true GEP20063777B (en) 2006-03-27

Family

ID=23211067

Family Applications (1)

Application Number Title Priority Date Filing Date
GE5446A GEP20063777B (en) 2001-08-15 2002-08-13 Crystals Including Malic Acid Salt of N-[2-(Diethylamino) Ethyl]-5-[(5-Fluoro-2-Oxo-3h-Indole-3-Ylidene) Methyl]-2, 4-Dimethyl-1h-Pyrrole-3-Carboxamide, Processes for Its Preparation and Compositions Thereof

Country Status (42)

Country Link
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EC (1) ECSP044975A (enExample)
ES (3) ES2623094T3 (enExample)
GE (1) GEP20063777B (enExample)
HR (1) HRP20040112B1 (enExample)
HU (1) HU229206B1 (enExample)
IL (1) IL160097A0 (enExample)
IS (1) IS7147A (enExample)
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UA (1) UA76483C2 (enExample)
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Publication number Publication date
NO326508B1 (no) 2008-12-15
NO20041054L (no) 2004-03-12
HUP0700036A2 (en) 2008-10-28
US20070191458A1 (en) 2007-08-16
BR0211612A (pt) 2004-08-24
ES2453164T3 (es) 2014-04-04
EA006445B1 (ru) 2005-12-29
SK902004A3 (sk) 2005-03-04
EP3168218B1 (en) 2018-11-14
CN1543462A (zh) 2004-11-03
EP2332934B1 (en) 2017-03-01
TNSN04028A1 (fr) 2006-06-01
TWI269796B (en) 2007-01-01
ES2623094T3 (es) 2017-07-10
US7435832B2 (en) 2008-10-14
WO2003016305A1 (en) 2003-02-27
CN100364991C (zh) 2008-01-30
PL216524B1 (pl) 2014-04-30
OA12650A (en) 2006-06-19
PT3168218T (pt) 2019-01-11
CO5550431A2 (es) 2005-08-31
EP2332934A1 (en) 2011-06-15
SI3168218T1 (sl) 2019-05-31
HRP20040112B1 (en) 2012-03-31
EA006445B9 (ru) 2017-02-28
EA200400183A1 (ru) 2004-08-26
IS7147A (is) 2004-02-10
PL368317A1 (en) 2005-03-21
SI1419151T1 (sl) 2014-04-30
MXPA04001452A (es) 2004-05-20
US20030069298A1 (en) 2003-04-10
KR100639281B1 (ko) 2006-10-31
EP1419151A1 (en) 2004-05-19
HK1088008A1 (zh) 2006-10-27
JP4159988B2 (ja) 2008-10-01
EP1419151B1 (en) 2014-02-26
CN1789264A (zh) 2006-06-21
CZ2004196A3 (cs) 2005-01-12
EP3168218A1 (en) 2017-05-17
RS53251B (sr) 2014-08-29
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