YU38103A - Nova jedinjenja askorbinske kiseline, postupci sinteze i način njihove primene - Google Patents

Nova jedinjenja askorbinske kiseline, postupci sinteze i način njihove primene

Info

Publication number
YU38103A
YU38103A YU38103A YUP38103A YU38103A YU 38103 A YU38103 A YU 38103A YU 38103 A YU38103 A YU 38103A YU P38103 A YUP38103 A YU P38103A YU 38103 A YU38103 A YU 38103A
Authority
YU
Yugoslavia
Prior art keywords
ascorbic acid
acid compounds
synthesis
application use
derivatives
Prior art date
Application number
YU38103A
Other languages
English (en)
Inventor
Matthias Rath
Aleksandra Niedzwiecki
Vadim Ivanov
Shrirang Netke
Waheed Roomi
Original Assignee
Matthias Rath
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Matthias Rath filed Critical Matthias Rath
Publication of YU38103A publication Critical patent/YU38103A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/62—Three oxygen atoms, e.g. ascorbic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)

Abstract

Pronalazak se odnosi na nova sintetska jedinjenja askorbinske kiseline sa lizinom i njegovim derivatima i/ili prolinom i njegovim derivatima. Ovaj pronalazak obezbedjuje farmaceutski delotvornu kompoziciju koja sadrži derivate aksorbinske kiseline sa lizinom i prolinom. Ovaj pronalazak takodje obuhvata postupke za upotrebu u istražviačke svrhe u okviru, ali se ne ograničavajući samo na primenu u, medicini, dijetetici, fiziologiji i farmakologiji.[The invention relates to the novel synthesis of ascorbic acid compounds with lysine and its derivatives and/or proline and its derivatives. The present invention provides pharmaceutically effective composition which comprises the ascorbic acid derivatives with lysine and proline. The present invention also includes methods of use in research fields including, but not limited to, medicine, nutrition, physiology, and pharmacology applications.
YU38103A 2001-08-24 2002-08-23 Nova jedinjenja askorbinske kiseline, postupci sinteze i način njihove primene YU38103A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31485701P 2001-08-24 2001-08-24

Publications (1)

Publication Number Publication Date
YU38103A true YU38103A (sh) 2006-05-25

Family

ID=23221754

Family Applications (1)

Application Number Title Priority Date Filing Date
YU38103A YU38103A (sh) 2001-08-24 2002-08-23 Nova jedinjenja askorbinske kiseline, postupci sinteze i način njihove primene

Country Status (19)

Country Link
US (2) US6864284B2 (sh)
EP (3) EP1423375A2 (sh)
JP (1) JP4162593B2 (sh)
KR (1) KR20040044472A (sh)
CN (3) CN100361987C (sh)
BR (1) BR0205944A (sh)
CA (1) CA2458344A1 (sh)
HR (1) HRP20040207A2 (sh)
HU (1) HUP0600084A2 (sh)
IL (4) IL155578A0 (sh)
MX (1) MXPA04001655A (sh)
NO (1) NO20031844L (sh)
NZ (3) NZ542240A (sh)
PL (1) PL373522A1 (sh)
RU (1) RU2309152C2 (sh)
UA (1) UA78223C2 (sh)
WO (2) WO2003018000A1 (sh)
YU (1) YU38103A (sh)
ZA (1) ZA200304712B (sh)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040067890A1 (en) * 2002-10-04 2004-04-08 Gupta Shyam K. Ascorbic acid salts of organic bases with enhanced bioavailability for synergictic anti-aging and skin protective cosmetic compositions
CN1805948A (zh) * 2003-04-21 2006-07-19 塔格拉生物科技有限公司 抗坏血酸的稳定衍生物
CN100346782C (zh) * 2004-05-21 2007-11-07 北京京卫信康医药科技发展有限公司 一种含氨基酸的维生素c组合物
KR100544159B1 (ko) * 2004-07-14 2006-01-24 센양 뉴라이프 인더스트리알 코 엘티디 아스코르빌 테트라이소팔미테이트와 디팔미토일하이드록시프롤린을 함유한 나노 에멀젼 및 이를함유하는 화장료 조성물
US20070002866A1 (en) * 2005-06-29 2007-01-04 Denso Corporation Receive power priority flooding in mobile ad hoc networks
UA100841C2 (en) 2006-02-21 2013-02-11 Мэри Кей, Инк. Normal;heading 1;heading 2;heading 3;STABLE VITAMIN C COMPOSITIONS
US20080188553A1 (en) * 2007-02-06 2008-08-07 Waheed M Roomi Novel ascorbic acid compounds, methods of synthesis and application use thereof
FR2913686B1 (fr) * 2007-03-14 2009-05-01 Oreal Nouveaux composes carbamates de vitamine c, compositions les comprenant, et utilisations
US8828960B2 (en) * 2007-07-17 2014-09-09 Idexx Laboratories, Inc. Amino acid vitamin ester compositions for controlled delivery of pharmaceutically active compounds
EP3478259A4 (en) * 2016-06-29 2020-02-26 Orasis Medical, Inc. ASCORBIC ACID-AMINO ACID CONJUGATES AND THEIR USE IN REGULATING THE LIQUID OUTLET
CN117777239A (zh) * 2017-09-15 2024-03-29 凯恩塞恩斯株式会社 作为自身免疫疾病及骨病治疗剂的肽的用途

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1273989A (fr) * 1960-09-09 1961-10-20 Marbou Procédé de préparation de l'ascorbate de lysine
US4424232A (en) * 1982-05-19 1984-01-03 Parkinson Richard W Treatment of herpes simplex
US4518614A (en) * 1982-11-04 1985-05-21 Redken Laboratories, Inc. Cosmetic preparation
JPS63190882A (ja) 1987-02-03 1988-08-08 Nippon Haipotsukusu:Kk アスコルビン酸誘導体及びそれを含有する皮膚脱色剤並びにその製造法
FR2650180B1 (fr) * 1989-07-31 1995-03-03 Chisso Corp Procede de production d'une feuille facilement soluble dans l'eau a base d'acide hyaluronique ou de hyaluronate et feuille ainsi obtenue
AU8416391A (en) * 1990-06-04 1992-01-07 Therapy 2000 Reduction of cardiovascular vessel occlusions with ascorbate and lipoprotein (a) binding inhibitors
JPH04247011A (ja) 1991-02-04 1992-09-03 Q P Corp リン脂質系アスコルビン酸誘導体及び該誘導体を含む皮膚外用剤
US5977073A (en) * 1991-06-06 1999-11-02 Life Sciences' Technologies, Inc. Nutrient composition for treatment of immune disorders
JPH0666958A (ja) * 1991-08-29 1994-03-11 Masaki Yoshigaki 目覚し時計の目覚し設定並びに目覚し音停止機構
JPH0678560A (ja) 1992-08-26 1994-03-18 Matsushita Electric Works Ltd インバータ装置
FR2715156B1 (fr) 1994-01-20 1996-03-01 Oreal Mono-esters d'acide cinnamique ou de ses dérivés et de vitamine C, leur procédé de préparation et leur utilisation comme anti-oxydants dans des compositions cosmétiques, pharmaceutiques ou alimentaires.
US5626883A (en) * 1994-04-15 1997-05-06 Metagenics, Inc. Ascorbic acid compositions providing enhanced human immune system activity
US5951990A (en) 1995-05-15 1999-09-14 Avon Products, Inc. Ascorbyl-phosphoryl-cholesterol
US5607968A (en) 1995-06-07 1997-03-04 Avon Products, Inc. Topical alkyl-2-O-L-ascorbyl-phosphates
FR2737971B1 (fr) 1995-08-25 1997-11-14 Lvmh Rech Utilisation de la vitamine c ou de ses derives ou analogues pour stimuler la synthese de l'elastine cutanee
US6162419A (en) 1996-11-26 2000-12-19 Nicholas V. Perricone Stabilized ascorbyl compositions
US5962517A (en) * 1997-01-31 1999-10-05 Murad; Howard Pharmaceutical compositions and methods for treating acne
EP0891771A1 (en) * 1997-07-08 1999-01-20 Health Now, Inc. Compositions comprising lysine and ascorbate compounds for the treatment and prevention of cardiovascular diseases

Also Published As

Publication number Publication date
WO2003018000A1 (en) 2003-03-06
BR0205944A (pt) 2004-12-28
NZ542240A (en) 2006-09-29
US20030119753A1 (en) 2003-06-26
EP2241559A3 (en) 2014-07-09
HRP20040207A2 (en) 2005-02-28
WO2003018568A2 (en) 2003-03-06
ZA200304712B (en) 2004-07-12
EP2241560A2 (en) 2010-10-20
NZ542241A (en) 2006-09-29
EP1423375A2 (en) 2004-06-02
PL373522A1 (en) 2005-09-05
CN1763027A (zh) 2006-04-26
CN100378087C (zh) 2008-04-02
NO20031844D0 (no) 2003-04-24
RU2309152C2 (ru) 2007-10-27
JP4162593B2 (ja) 2008-10-08
EP2241559A2 (en) 2010-10-20
CN100361987C (zh) 2008-01-16
US7230124B2 (en) 2007-06-12
IL155578A0 (en) 2003-11-23
WO2003018568A3 (en) 2003-12-04
IL155578A (en) 2006-12-10
RU2004108687A (ru) 2005-09-20
US20040167077A1 (en) 2004-08-26
US6864284B2 (en) 2005-03-08
NO20031844L (no) 2003-06-12
EP2241560A3 (en) 2014-07-09
HUP0600084A2 (en) 2006-06-28
NZ531430A (en) 2006-05-26
JP2005501867A (ja) 2005-01-20
IL176523A0 (en) 2006-10-05
MXPA04001655A (es) 2004-05-31
UA78223C2 (uk) 2007-03-15
CN1518545A (zh) 2004-08-04
CA2458344A1 (en) 2003-03-06
IL176524A0 (en) 2006-10-05
KR20040044472A (ko) 2004-05-28
CN1763028A (zh) 2006-04-26
CN100360514C (zh) 2008-01-09

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