AP1660A - Crystals including a malic acid salt of N - [2 -(diethylamino) ethyl] - 5 - [ (5 - fluoro -2-oxo - 3H -indole -3 - ylidene) methyl] - 2,4 - dimethyl - 1H- pyrrole -3 -carboxamide, processes for its preparation and compositions thereof. - Google Patents

Crystals including a malic acid salt of N - [2 -(diethylamino) ethyl] - 5 - [ (5 - fluoro -2-oxo - 3H -indole -3 - ylidene) methyl] - 2,4 - dimethyl - 1H- pyrrole -3 -carboxamide, processes for its preparation and compositions thereof.

Info

Publication number
AP1660A
AP1660A APAP/P/2004/002976A AP2004002976A AP1660A AP 1660 A AP1660 A AP 1660A AP 2004002976 A AP2004002976 A AP 2004002976A AP 1660 A AP1660 A AP 1660A
Authority
AP
ARIPO
Prior art keywords
ylidene
carboxamide
pyrrole
oxo
dimethyl
Prior art date
Application number
APAP/P/2004/002976A
Other languages
English (en)
Other versions
AP2004002976A0 (en
Inventor
Michael Hawley
Thomas J Fleck
Stephen P Prescott
Mark T Maloney
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23211067&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP1660(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of AP2004002976A0 publication Critical patent/AP2004002976A0/xx
Application granted granted Critical
Publication of AP1660A publication Critical patent/AP1660A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
APAP/P/2004/002976A 2001-08-15 2002-08-13 Crystals including a malic acid salt of N - [2 -(diethylamino) ethyl] - 5 - [ (5 - fluoro -2-oxo - 3H -indole -3 - ylidene) methyl] - 2,4 - dimethyl - 1H- pyrrole -3 -carboxamide, processes for its preparation and compositions thereof. AP1660A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31235301P 2001-08-15 2001-08-15
PCT/US2002/025649 WO2003016305A1 (en) 2001-08-15 2002-08-13 Crystals including a malic acid salt of n-[2-(diethylamino) ethyl]-5-[(5-fluoro-2-oxo-3h-indole-3-ylidene) methyl]-2, 4-dimethyl-1h-pyrrole-3-carboxamide, processes for its preparation and compositions thereof

Publications (2)

Publication Number Publication Date
AP2004002976A0 AP2004002976A0 (en) 2004-03-31
AP1660A true AP1660A (en) 2006-09-09

Family

ID=23211067

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/2004/002976A AP1660A (en) 2001-08-15 2002-08-13 Crystals including a malic acid salt of N - [2 -(diethylamino) ethyl] - 5 - [ (5 - fluoro -2-oxo - 3H -indole -3 - ylidene) methyl] - 2,4 - dimethyl - 1H- pyrrole -3 -carboxamide, processes for its preparation and compositions thereof.

Country Status (42)

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US (2) US20030069298A1 (enExample)
EP (3) EP3168218B1 (enExample)
JP (1) JP4159988B2 (enExample)
KR (1) KR100639281B1 (enExample)
CN (2) CN100364991C (enExample)
AP (1) AP1660A (enExample)
AR (1) AR036261A1 (enExample)
AU (1) AU2002324684B2 (enExample)
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TW (1) TWI269796B (enExample)
UA (1) UA76483C2 (enExample)
WO (1) WO2003016305A1 (enExample)
ZA (1) ZA200400706B (enExample)

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KR100639281B1 (ko) 2006-10-31
US20030069298A1 (en) 2003-04-10
PT3168218T (pt) 2019-01-11
DK1419151T3 (da) 2014-03-31
CY1121552T1 (el) 2020-05-29
EP2332934A1 (en) 2011-06-15
TNSN04028A1 (fr) 2006-06-01
KR20040030074A (ko) 2004-04-08
CN1789264A (zh) 2006-06-21
AU2002324684B2 (en) 2006-10-05
EA006445B9 (ru) 2017-02-28
NO20041054L (no) 2004-03-12
HUP0700036A2 (en) 2008-10-28
ES2705063T3 (es) 2019-03-21
JP2005503386A (ja) 2005-02-03
AP2004002976A0 (en) 2004-03-31
IS7147A (is) 2004-02-10
OA12650A (en) 2006-06-19
ZA200400706B (en) 2005-05-25
ECSP044975A (es) 2004-03-23
CZ2004196A3 (cs) 2005-01-12
CU20040029A7 (es) 2008-03-14
EP1419151A1 (en) 2004-05-19
EP2332934B1 (en) 2017-03-01
IL160097A0 (en) 2004-06-20
MA27058A1 (fr) 2004-12-20
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