TN2015000381A1 - Substituted 2-aza-bicyclo [2.2.1] heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of cathepsin c - Google Patents

Substituted 2-aza-bicyclo [2.2.1] heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of cathepsin c

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Publication number
TN2015000381A1
TN2015000381A1 TN2015000381A TN2015000381A TN2015000381A1 TN 2015000381 A1 TN2015000381 A1 TN 2015000381A1 TN 2015000381 A TN2015000381 A TN 2015000381A TN 2015000381 A TN2015000381 A TN 2015000381A TN 2015000381 A1 TN2015000381 A1 TN 2015000381A1
Authority
TN
Tunisia
Prior art keywords
cathepsin
aza
bicyclo
heptane
cyano
Prior art date
Application number
TN2015000381A
Other languages
English (en)
Inventor
Ralf Anderskewitz
Thorsten Oost
Stefan Peters
Matthias Grauert
Marc Grundl
Peter Wilhelm Haebel
Alexander Pautsch
Florian Binder
Viktor Vintonyak
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of TN2015000381A1 publication Critical patent/TN2015000381A1/en

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    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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