HUE053431T2 - Szubsztituált 2-aza-biciklo[2.2.1]heptán-3-karbonsav-(benzil-ciano-metil)-amidok, mint a katepszin-C inhibitorai - Google Patents

Szubsztituált 2-aza-biciklo[2.2.1]heptán-3-karbonsav-(benzil-ciano-metil)-amidok, mint a katepszin-C inhibitorai

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Publication number
HUE053431T2
HUE053431T2 HUE14709652A HUE14709652A HUE053431T2 HU E053431 T2 HUE053431 T2 HU E053431T2 HU E14709652 A HUE14709652 A HU E14709652A HU E14709652 A HUE14709652 A HU E14709652A HU E053431 T2 HUE053431 T2 HU E053431T2
Authority
HU
Hungary
Prior art keywords
cathepsin
aza
bicyclo
heptane
cyano
Prior art date
Application number
HUE14709652A
Other languages
English (en)
Hungarian (hu)
Inventor
Ralf Anderskewitz
Matthias Grauert
Marc Grundl
Peter Haebel
Thorsten Oost
Alexander Pautsch
Stefan Peters
Florian Binder
Viktor Vintonyak
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of HUE053431T2 publication Critical patent/HUE053431T2/hu

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    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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