SG11201507382QA - Substituted 2-aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of cathepsin c - Google Patents

Substituted 2-aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of cathepsin c

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Publication number
SG11201507382QA
SG11201507382QA SG11201507382QA SG11201507382QA SG11201507382QA SG 11201507382Q A SG11201507382Q A SG 11201507382QA SG 11201507382Q A SG11201507382Q A SG 11201507382QA SG 11201507382Q A SG11201507382Q A SG 11201507382QA SG 11201507382Q A SG11201507382Q A SG 11201507382QA
Authority
SG
Singapore
Prior art keywords
cathepsin
aza
bicyclo
heptane
cyano
Prior art date
Application number
SG11201507382QA
Inventor
Ralf Anderskewitz
Matthias Grauert
Marc Grundl
Peter Wilhelm Haebel
Thorsten Oost
Alexander Pautsch
Stefan Peters
Florian Binder
Viktor Vintonyak
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of SG11201507382QA publication Critical patent/SG11201507382QA/en

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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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    • C07D498/04—Ortho-condensed systems
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