TN2009000450A1 - Derives de pyridine - Google Patents
Derives de pyridineInfo
- Publication number
- TN2009000450A1 TN2009000450A1 TNP2009000450A TN2009000450A TN2009000450A1 TN 2009000450 A1 TN2009000450 A1 TN 2009000450A1 TN P2009000450 A TNP2009000450 A TN P2009000450A TN 2009000450 A TN2009000450 A TN 2009000450A TN 2009000450 A1 TN2009000450 A1 TN 2009000450A1
- Authority
- TN
- Tunisia
- Prior art keywords
- pyridine derivatives
- compounds
- preparation
- solvates
- pain
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Abstract
La présente invention concerne des composés de formule (I) : (I) et leurs sels et produits de solvation pharmaceutiquement acceptables, des procédés pour la préparation des intermédiaires utilisés dans la préparation de et des compositions contenant ces composés et les utilisations de ces composés pour le traitement de la douleur.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US91574507P | 2007-05-03 | 2007-05-03 | |
US95753607P | 2007-08-23 | 2007-08-23 | |
PCT/IB2008/001050 WO2008135826A2 (fr) | 2007-05-03 | 2008-04-21 | Dérivés de la pyridine |
Publications (1)
Publication Number | Publication Date |
---|---|
TN2009000450A1 true TN2009000450A1 (fr) | 2011-03-31 |
Family
ID=39855225
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TNP2009000450A TN2009000450A1 (fr) | 2007-05-03 | 2009-10-29 | Derives de pyridine |
Country Status (33)
Country | Link |
---|---|
US (1) | US8134007B2 (fr) |
EP (1) | EP2183241B1 (fr) |
JP (1) | JP4657384B2 (fr) |
KR (1) | KR20100007956A (fr) |
CN (1) | CN101675040A (fr) |
AP (1) | AP2516A (fr) |
AR (1) | AR070636A1 (fr) |
AU (1) | AU2008247102B2 (fr) |
BR (1) | BRPI0810202A2 (fr) |
CA (1) | CA2684105C (fr) |
CL (1) | CL2008001268A1 (fr) |
CO (1) | CO6251367A2 (fr) |
CR (1) | CR11061A (fr) |
CU (1) | CU23846B1 (fr) |
DO (1) | DOP2009000254A (fr) |
EA (1) | EA015952B1 (fr) |
EC (1) | ECSP099710A (fr) |
ES (1) | ES2398606T3 (fr) |
GE (1) | GEP20125379B (fr) |
GT (1) | GT200900280A (fr) |
IL (1) | IL201569A0 (fr) |
MA (1) | MA31419B1 (fr) |
MX (1) | MX2009011816A (fr) |
NI (1) | NI200900192A (fr) |
NZ (1) | NZ581614A (fr) |
PA (1) | PA8779201A1 (fr) |
PE (1) | PE20090730A1 (fr) |
SV (1) | SV2009003400A (fr) |
TN (1) | TN2009000450A1 (fr) |
TW (1) | TWI375675B (fr) |
UY (1) | UY31063A1 (fr) |
WO (1) | WO2008135826A2 (fr) |
ZA (1) | ZA200907609B (fr) |
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AR044688A1 (es) | 2003-06-12 | 2005-09-21 | Euro Celtique Sa | Agentes terapeuticos utiles para el tratamiento del dolor |
ATE412646T1 (de) | 2003-09-22 | 2008-11-15 | Euro Celtique Sa | Zur behandlung von schmerzen geeignete therapeutische mittel |
CN1950332A (zh) | 2004-03-02 | 2007-04-18 | 神经能质公司 | 经杂烷基取代的联苯-4-羧酸芳基醯胺类似物 |
JP4056081B1 (ja) * | 2004-07-23 | 2008-03-05 | ファイザー・インク | ピリジン誘導体 |
CA2585490A1 (fr) | 2004-11-12 | 2006-05-18 | Galapagos Nv | Composes heteroaromatiques de l'azote qui se lient au site actif d'enzymes de type proteines kinases |
US20060106011A1 (en) * | 2004-11-12 | 2006-05-18 | Bock Mark G | 2-(Bicyclo)alkylamino-derivatives as mediators of chronic pain and inflammation |
CN101253152A (zh) | 2005-09-02 | 2008-08-27 | 安斯泰来制药株式会社 | 作为rock抑制剂的酰胺衍生物 |
AU2006289281B2 (en) | 2005-09-09 | 2012-05-17 | KaNDy Therapeutics Ltd. | Pyridine derivatives and their use in the treatment of psychotic disorders |
EP1764095A1 (fr) | 2005-09-20 | 2007-03-21 | Revotar Biopharmaceuticals AG | Nouveaux derivés de nitrocatéchol ayant activité de ligande de selectine |
EP1764093A1 (fr) | 2005-09-20 | 2007-03-21 | Revotar Biopharmaceuticals AG | Nouveaux composés aromatiques et leur application médical |
ES2274712B1 (es) | 2005-10-06 | 2008-03-01 | Laboratorios Almirall S.A. | Nuevos derivados imidazopiridina. |
TWI385169B (zh) * | 2005-10-31 | 2013-02-11 | Eisai R&D Man Co Ltd | 經雜環取代之吡啶衍生物及含有彼之抗真菌劑 |
TW200732320A (en) | 2005-10-31 | 2007-09-01 | Biolipox Ab | Pyrazoles useful in the treatment of inflammation |
BRPI0618079A2 (pt) | 2005-10-31 | 2011-08-16 | Biolipox Ab | composto ou um sal farmaceuticamente aceitável do mesmo, formulação farmacêutica, uso de um composto ou um sal farmaceuticamente aceitável do mesmo, método de tratamento de uma doença, produto de combinação, e, processos para a preparação de um composto, de uma formulação farmacêutica, e de um produto de combinação |
NL2000284C2 (nl) | 2005-11-04 | 2007-09-28 | Pfizer Ltd | Pyrazine-derivaten. |
HUE032640T2 (en) | 2005-11-08 | 2017-10-30 | Vertex Pharma | Heterocyclic modulator of ATP-binding cassette transcripts |
WO2007058990A2 (fr) | 2005-11-14 | 2007-05-24 | Kemia, Inc. | Therapie a base d’inhibiteurs de cytokine |
US8106190B2 (en) | 2005-11-30 | 2012-01-31 | Astellas Pharma Inc. | 2-aminobenzamide derivatives |
CA2633329A1 (fr) | 2006-01-23 | 2007-07-26 | Pfizer Limited | Derives de pyridine en tant que modulateurs du canal sodium |
EP1998612A4 (fr) | 2006-01-25 | 2010-11-24 | Synta Pharmaceuticals Corp | Composés biaryle substitués destinés à des utilisations contre des inflammations et des troubles immunitaires |
AU2007211276B2 (en) | 2006-01-31 | 2013-06-06 | Synta Pharmaceuticals Corp. | Pyridylphenyl compounds for inflammation and immune-related uses |
CA2640672A1 (fr) | 2006-02-17 | 2007-08-23 | Pfizer Limited | Derives de 3-deazapurine en tant que modulateurs de tlr7 |
SI2402317T1 (sl) | 2006-03-31 | 2013-10-30 | Novartis Ag | DGAT inhibitor |
PE20080906A1 (es) | 2006-08-17 | 2008-07-05 | Kemia Inc | Derivados heteroarilo como inhibidores de citocina |
EP2125778A1 (fr) | 2006-12-22 | 2009-12-02 | Millennium Pharmaceuticals, Inc. | Certains dérivés de pyrazoline avec une activité inhibitrice de kinase |
US7759344B2 (en) | 2007-01-09 | 2010-07-20 | Amgen Inc. | Bis-aryl amide derivatives and methods of use |
BRPI0808523A2 (pt) | 2007-03-01 | 2014-08-19 | Novartis Vaccines & Diagnostic | Inibidores de pim cinase e métodos de seu uso |
US20100227872A1 (en) | 2007-05-03 | 2010-09-09 | Mark Ian Kemp | Pyrazine derivatives |
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2008
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- 2008-04-21 AU AU2008247102A patent/AU2008247102B2/en not_active Ceased
- 2008-04-21 CN CN200880014589A patent/CN101675040A/zh active Pending
- 2008-04-21 ES ES08737559T patent/ES2398606T3/es active Active
- 2008-04-21 CA CA2684105A patent/CA2684105C/fr not_active Expired - Fee Related
- 2008-04-21 JP JP2010504893A patent/JP4657384B2/ja not_active Expired - Fee Related
- 2008-04-21 GE GEAP200811541A patent/GEP20125379B/en unknown
- 2008-04-21 MX MX2009011816A patent/MX2009011816A/es active IP Right Grant
- 2008-04-21 KR KR1020097025183A patent/KR20100007956A/ko active IP Right Grant
- 2008-04-21 AP AP2009005009A patent/AP2516A/xx active
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- 2008-04-21 EP EP08737559A patent/EP2183241B1/fr active Active
- 2008-04-21 WO PCT/IB2008/001050 patent/WO2008135826A2/fr active Application Filing
- 2008-04-30 UY UY31063A patent/UY31063A1/es not_active Application Discontinuation
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