SV2002000287A - Uso de inhibidor de la quinasa dependiente de la ciclina para preparar una composicion farmaceutica util para tratar enfermedades neurodegenerativas - Google Patents
Uso de inhibidor de la quinasa dependiente de la ciclina para preparar una composicion farmaceutica util para tratar enfermedades neurodegenerativasInfo
- Publication number
- SV2002000287A SV2002000287A SV2001000287A SV2001000287A SV2002000287A SV 2002000287 A SV2002000287 A SV 2002000287A SV 2001000287 A SV2001000287 A SV 2001000287A SV 2001000287 A SV2001000287 A SV 2001000287A SV 2002000287 A SV2002000287 A SV 2002000287A
- Authority
- SV
- El Salvador
- Prior art keywords
- neurodegenerative diseases
- dependent kinase
- prepare
- pharmaceutical composition
- kinase inhibitor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17840000P | 2000-01-27 | 2000-01-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
SV2002000287A true SV2002000287A (es) | 2002-01-08 |
Family
ID=22652409
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SV2001000287A SV2002000287A (es) | 2000-01-27 | 2001-01-22 | Uso de inhibidor de la quinasa dependiente de la ciclina para preparar una composicion farmaceutica util para tratar enfermedades neurodegenerativas |
Country Status (22)
Country | Link |
---|---|
US (1) | US20040224958A1 (hu) |
EP (1) | EP1255755A1 (hu) |
JP (1) | JP2003523358A (hu) |
KR (1) | KR20020070520A (hu) |
CN (1) | CN1433417A (hu) |
AR (1) | AR029437A1 (hu) |
AU (1) | AU1808601A (hu) |
BR (1) | BR0017075A (hu) |
CA (1) | CA2394525A1 (hu) |
CO (1) | CO5280216A1 (hu) |
CZ (1) | CZ20022521A3 (hu) |
GT (1) | GT200100005A (hu) |
HN (1) | HN2001000012A (hu) |
HU (1) | HUP0203803A3 (hu) |
IL (1) | IL150742A0 (hu) |
PA (1) | PA8510801A1 (hu) |
PE (1) | PE20011228A1 (hu) |
PL (1) | PL357634A1 (hu) |
SK (1) | SK10772002A3 (hu) |
SV (1) | SV2002000287A (hu) |
TN (1) | TNSN01018A1 (hu) |
WO (1) | WO2001055148A1 (hu) |
Families Citing this family (79)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7053070B2 (en) * | 2000-01-25 | 2006-05-30 | Warner-Lambert Company | Pyrido[2,3-d]pyrimidine-2,7-diamine kinase inhibitors |
US7235551B2 (en) * | 2000-03-02 | 2007-06-26 | Smithkline Beecham Corporation | 1,5-disubstituted-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one compounds and their use in treating csbp/p38 kinase mediated diseases |
EP1333833B1 (en) * | 2000-10-23 | 2011-08-24 | GlaxoSmithKline LLC | Novel trisubstituted-8H-pyrido[2,3-d]pyrimidin-7-one compound for the treatment of CSBP/p38 kinase mediated diseases |
AU2002233706C1 (en) * | 2001-02-26 | 2005-12-22 | Tanabe Seiyaku Co., Ltd. | Pyridopyrimidine or naphthyridine derivative |
JP4172541B2 (ja) | 2001-04-09 | 2008-10-29 | ノバルティス バクシンズ アンド ダイアグノスティックス, インコーポレーテッド | グアニジノ化合物 |
US7105667B2 (en) | 2001-05-01 | 2006-09-12 | Bristol-Myers Squibb Co. | Fused heterocyclic compounds and use thereof |
PE20030008A1 (es) | 2001-06-19 | 2003-01-22 | Bristol Myers Squibb Co | Inhibidores duales de pde 7 y pde 4 |
EP1397142A4 (en) | 2001-06-19 | 2004-11-03 | Bristol Myers Squibb Co | PYRIMIDINE PHOSPHODIESTERASE (PDE) INHIBITORS 7 |
ATE407678T1 (de) | 2001-10-17 | 2008-09-15 | Boehringer Ingelheim Pharma | Pyrimidinderivate, arzneimittel enthaltend diese verbindungen, deren verwendung und verfahren zu ihrer herstellung |
EP1453516A2 (de) | 2001-10-17 | 2004-09-08 | Boehringer Ingelheim Pharma GmbH & Co.KG | 5-substituierte 4-amino-2-phenylamino-pyrimdinderivate und ihre verwendung als beta-amyloid modulatoren |
GEP20063909B (en) | 2002-01-22 | 2006-08-25 | Warner Lambert Co | 2-(PYRIDIN-2-YLAMINO)-PYRIDO[2,3d] PYRIMIDIN-7-ONES |
ES2291630T3 (es) * | 2002-04-19 | 2008-03-01 | Smithkline Beecham Corporation | Nuevos compuestos. |
US7384937B2 (en) | 2002-11-06 | 2008-06-10 | Bristol-Myers Squibb Co. | Fused heterocyclic compounds and use thereof |
JP2006508997A (ja) * | 2002-11-28 | 2006-03-16 | シエーリング アクチエンゲゼルシャフト | Chk−、Pdk−およびAkt−阻害性ピリミジン、それらの製造および薬剤としての使用 |
US7157455B2 (en) * | 2003-02-10 | 2007-01-02 | Hoffmann-La Roche Inc. | 4-Aminopyrimidine-5-one derivatives |
CN100372851C (zh) | 2003-05-05 | 2008-03-05 | 弗·哈夫曼-拉罗切有限公司 | 具有crf活性的稠合的嘧啶衍生物 |
ATE356124T1 (de) | 2003-11-13 | 2007-03-15 | Hoffmann La Roche | Hydroxyalkylsubstituierte pyrido-7-pyrimidin-7- one |
PL1713806T3 (pl) * | 2004-02-14 | 2013-09-30 | Irm Llc | Związki i kompozycje jako inhibitory kinaz białkowych |
JP2007523151A (ja) * | 2004-02-18 | 2007-08-16 | ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー | 2−(ピリジン−3−イルアミノ)−ピリド[2,3−d]ピリミジン−7−オン |
EP1786817A1 (de) * | 2004-08-26 | 2007-05-23 | Boehringer Ingelheim International GmbH | Pteridinone als plk (polo like kinase) inhibitoren |
JP5111113B2 (ja) | 2004-12-13 | 2012-12-26 | サネシス ファーマシューティカルズ, インコーポレイテッド | Rafキナーゼ阻害剤として有用なピリドピリミジノン、ジヒドロピリミドピリミジノンおよびプテリジノン |
MY145281A (en) | 2005-03-25 | 2012-01-13 | Glaxo Group Ltd | Novel compounds |
PE20061193A1 (es) * | 2005-03-25 | 2006-12-02 | Glaxo Group Ltd | DERIVADOS DE 3,4-DIHIDROPIRIMIDO[4,5-d]PIRIMIDIN-2-[1H]-0NA COMO INHIBIDORES DE QUINASA p38 |
EP1865959A2 (en) * | 2005-03-25 | 2007-12-19 | Glaxo Group Limited | Process for preparing pyridoý2,3-d¨pyrimidin-7-one and 3,4-dihydropyrimidoý4,5-d¨pyrimidin-2(1h)-one derivatives |
EP1868612A4 (en) * | 2005-03-25 | 2010-03-24 | Glaxo Group Ltd | NOVEL CONNECTIONS |
EA201200669A1 (ru) | 2005-10-07 | 2012-11-30 | Экселиксис, Инк. | ПИРИДОПИРИМИДИНОНОВЫЕ ИНГИБИТОРЫ PI3Kα |
WO2007044813A1 (en) | 2005-10-07 | 2007-04-19 | Exelixis, Inc. | PYRIDOPYRIMIDINONE INHIBITORS OF PI3Kα |
RS51927B (en) | 2006-09-15 | 2012-02-29 | Pfizer Products Inc. | PIRIDO (2,3-D) PIRIMIDINONE COMPOUNDS AND THEIR USE AS INHIBITORS P13 |
JP5302389B2 (ja) * | 2008-04-29 | 2013-10-02 | エフ.ホフマン−ラ ロシュ アーゲー | Jnkのピリミジニルピリドンインヒビター |
JP2012504628A (ja) | 2008-09-30 | 2012-02-23 | エグゼリクシス, インコーポレイテッド | PI3KαおよびmTORのピリドピリミジノン阻害剤 |
WO2010046273A2 (en) | 2008-10-22 | 2010-04-29 | F. Hoffmann-La Roche Ag | Pyrimidinyl pyridone inhibitors of jnk |
EP2504011A4 (en) * | 2009-11-23 | 2013-07-31 | Afraxis Inc | METHOD FOR TREATING EASY COGNITIVE IMPAIRMENT |
US8889696B2 (en) | 2009-12-18 | 2014-11-18 | Temple University—Of the Commonwealth System of Higher Education | Substituted pyrido[2,3-d]pyrimidin-7(8H)-ones and therapeutic uses thereof |
US8901137B2 (en) | 2010-02-09 | 2014-12-02 | Exelixis, Inc. | Methods of treating cancer using pyridopyrimidinone inhibitors of PI3K and mTOR in combination with autophagy inhibitors |
WO2011156646A2 (en) * | 2010-06-09 | 2011-12-15 | Afraxis, Inc. | 6-(sulfonylaryl)pyrido[2,3-d]pyrimidin-7(8h)-ones for the treatment of cns disorders |
EP2580213A4 (en) * | 2010-06-09 | 2013-12-25 | Afraxis Holdings Inc | 8- (HETEROARYLMETHYL) PYRIDO [2,3-D] PYRIMIDIN-7 (8H) -ONES FOR THE TREATMENT OF CNS DISORDERS |
US20130338153A1 (en) * | 2010-06-10 | 2013-12-19 | Afraxis, Inc. | 8-(2'-heterocycyl)pyrido[2.3-d]pyrimidin-7(8h)-ones for the treatment of cns disorders |
WO2011156786A2 (en) * | 2010-06-10 | 2011-12-15 | Afraxis, Inc. | 6-(ethynyl)pyrido[2,3-d]pyrimidin-7(8h)-ones for the treatment of cns disorders |
EP2580216A4 (en) * | 2010-06-10 | 2014-07-23 | Afraxis Holdings Inc | 8- (SULFONYLBENZYL) PYRIDO- [2,3-D-] PYRIMIDIN-7- (8H) -ONE FOR THE TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM |
PT2600719E (pt) * | 2010-08-05 | 2014-12-22 | Univ Temple | 8 ¿ alquilo -2 - substituído 7 ¿ oxo ¿ 7,8 ¿ diidropirido [2,3 ¿ d] pirimidina ¿ 6 ¿ carbonitrilos e seus usos |
US8754114B2 (en) | 2010-12-22 | 2014-06-17 | Incyte Corporation | Substituted imidazopyridazines and benzimidazoles as inhibitors of FGFR3 |
AU2013235344B2 (en) * | 2012-03-22 | 2017-03-16 | Oscotec Inc. | Substituted pyridopyrimidine compounds and their use as FLT3 inhibitors |
WO2013170671A1 (zh) * | 2012-05-14 | 2013-11-21 | 华东理工大学 | 蝶啶酮衍生物及其作为egfr、blk、flt3抑制剂的应用 |
CA2876689C (en) | 2012-06-13 | 2022-04-26 | Incyte Corporation | Substituted tricyclic compounds as fgfr inhibitors |
WO2014026125A1 (en) | 2012-08-10 | 2014-02-13 | Incyte Corporation | Pyrazine derivatives as fgfr inhibitors |
US9266892B2 (en) | 2012-12-19 | 2016-02-23 | Incyte Holdings Corporation | Fused pyrazoles as FGFR inhibitors |
ES2817448T3 (es) | 2013-03-14 | 2021-04-07 | Icahn School Med Mount Sinai | Compuestos de pirimidina como inhibidores de quinasas |
RS56924B9 (sr) | 2013-04-19 | 2019-09-30 | Incyte Holdings Corp | Biciklični heterocikli kao fgfr inhibitori |
KR20160035411A (ko) * | 2014-09-23 | 2016-03-31 | 주식회사 오스코텍 | LRRK2 (Leucine Rich Repeat Kinase 2) 키나제 억제제로서의 피리도피리미딘 유도체 화합물 |
US10851105B2 (en) | 2014-10-22 | 2020-12-01 | Incyte Corporation | Bicyclic heterocycles as FGFR4 inhibitors |
MX2017010673A (es) | 2015-02-20 | 2018-03-21 | Incyte Corp | Heterociclos biciclicos como inhibidores de receptores del factor de crecimiento fibroblastico (fgfr). |
MA41551A (fr) | 2015-02-20 | 2017-12-26 | Incyte Corp | Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4 |
US9580423B2 (en) | 2015-02-20 | 2017-02-28 | Incyte Corporation | Bicyclic heterocycles as FGFR4 inhibitors |
US11225492B2 (en) | 2015-12-13 | 2022-01-18 | Hangzhou Innogate Pharma Co., Ltd. | Heterocycles useful as anti-cancer agents |
US10449195B2 (en) | 2016-03-29 | 2019-10-22 | Shenzhen Pharmacin Co., Ltd. | Pharmaceutical formulation of palbociclib and a preparation method thereof |
KR102236605B1 (ko) * | 2016-08-15 | 2021-04-05 | 화이자 인코포레이티드 | 피리도피리미딘온 cdk2/4/6 억제제 |
JP6545747B2 (ja) * | 2017-05-09 | 2019-07-17 | 山田化学工業株式会社 | 色素化合物 |
AR111960A1 (es) | 2017-05-26 | 2019-09-04 | Incyte Corp | Formas cristalinas de un inhibidor de fgfr y procesos para su preparación |
EA036060B1 (ru) * | 2017-07-17 | 2020-09-21 | Пфайзер Инк. | Пиридопиримидиноновые ингибиторы cdk2/4/6 |
SG11202010882XA (en) | 2018-05-04 | 2020-11-27 | Incyte Corp | Salts of an fgfr inhibitor |
EP3788047A2 (en) | 2018-05-04 | 2021-03-10 | Incyte Corporation | Solid forms of an fgfr inhibitor and processes for preparing the same |
ES2929406T3 (es) * | 2018-05-21 | 2022-11-29 | Nerviano Medical Sciences Srl | Compuestos de piridonas heterocondensadas y su uso como inhibidores de IDH |
US20210261547A1 (en) * | 2018-06-27 | 2021-08-26 | Tufts Medical Center, Inc. | Pyridopyrimidine compounds and methods of their use |
US11066404B2 (en) | 2018-10-11 | 2021-07-20 | Incyte Corporation | Dihydropyrido[2,3-d]pyrimidinone compounds as CDK2 inhibitors |
US11628162B2 (en) | 2019-03-08 | 2023-04-18 | Incyte Corporation | Methods of treating cancer with an FGFR inhibitor |
US11919904B2 (en) | 2019-03-29 | 2024-03-05 | Incyte Corporation | Sulfonylamide compounds as CDK2 inhibitors |
CA3137869A1 (en) * | 2019-05-16 | 2020-11-19 | Gregory Cuny | Protein kinase inhibitors and uses thereof for the treatment of diseases and conditions |
US11591329B2 (en) | 2019-07-09 | 2023-02-28 | Incyte Corporation | Bicyclic heterocycles as FGFR inhibitors |
WO2021072232A1 (en) | 2019-10-11 | 2021-04-15 | Incyte Corporation | Bicyclic amines as cdk2 inhibitors |
MX2022004513A (es) | 2019-10-14 | 2022-07-19 | Incyte Corp | Heterociclos biciclicos como inhibidores de los receptores del factor de crecimiento de fibroblastos (fgfr). |
WO2021076728A1 (en) | 2019-10-16 | 2021-04-22 | Incyte Corporation | Bicyclic heterocycles as fgfr inhibitors |
US11697648B2 (en) | 2019-11-26 | 2023-07-11 | Theravance Biopharma R&D Ip, Llc | Fused pyrimidine pyridinone compounds as JAK inhibitors |
US11897891B2 (en) | 2019-12-04 | 2024-02-13 | Incyte Corporation | Tricyclic heterocycles as FGFR inhibitors |
CR20220285A (es) | 2019-12-04 | 2022-10-27 | Incyte Corp | Derivados de un inhibidor de fgfr |
WO2021183994A1 (en) * | 2020-03-13 | 2021-09-16 | Prosenestar Llc | Pyrido[2,3-d]pyrimidin-7(8h)-ones as cdk inhibitors |
CN114306245A (zh) | 2020-09-29 | 2022-04-12 | 深圳市药欣生物科技有限公司 | 无定形固体分散体的药物组合物及其制备方法 |
WO2022261160A1 (en) | 2021-06-09 | 2022-12-15 | Incyte Corporation | Tricyclic heterocycles as fgfr inhibitors |
US11981671B2 (en) | 2021-06-21 | 2024-05-14 | Incyte Corporation | Bicyclic pyrazolyl amines as CDK2 inhibitors |
US11976073B2 (en) | 2021-12-10 | 2024-05-07 | Incyte Corporation | Bicyclic amines as CDK2 inhibitors |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5733920A (en) * | 1995-10-31 | 1998-03-31 | Mitotix, Inc. | Inhibitors of cyclin dependent kinases |
FR2741881B1 (fr) * | 1995-12-01 | 1999-07-30 | Centre Nat Rech Scient | Nouveaux derives de purine possedant notamment des prorietes anti-proliferatives et leurs applications biologiques |
US6498163B1 (en) * | 1997-02-05 | 2002-12-24 | Warner-Lambert Company | Pyrido[2,3-D]pyrimidines and 4-aminopyrimidines as inhibitors of cellular proliferation |
KR20000070751A (ko) * | 1997-02-05 | 2000-11-25 | 로즈 암스트롱, 크리스틴 에이. 트러트웨인 | 세포 증식 억제제로서의 피리도[2,3-d]피리미딘 및 4-아미노피리미딘 |
-
2000
- 2000-11-30 BR BR0017075-5A patent/BR0017075A/pt not_active IP Right Cessation
- 2000-11-30 CA CA002394525A patent/CA2394525A1/en not_active Abandoned
- 2000-11-30 KR KR1020027009631A patent/KR20020070520A/ko not_active Application Discontinuation
- 2000-11-30 HU HU0203803A patent/HUP0203803A3/hu unknown
- 2000-11-30 WO PCT/US2000/032572 patent/WO2001055148A1/en not_active Application Discontinuation
- 2000-11-30 CN CN00818672A patent/CN1433417A/zh active Pending
- 2000-11-30 IL IL15074200A patent/IL150742A0/xx unknown
- 2000-11-30 EP EP00980883A patent/EP1255755A1/en not_active Withdrawn
- 2000-11-30 AU AU18086/01A patent/AU1808601A/en not_active Abandoned
- 2000-11-30 CZ CZ20022521A patent/CZ20022521A3/cs unknown
- 2000-11-30 JP JP2001561007A patent/JP2003523358A/ja active Pending
- 2000-11-30 PL PL00357634A patent/PL357634A1/xx not_active Application Discontinuation
- 2000-11-30 US US10/181,866 patent/US20040224958A1/en not_active Abandoned
- 2000-11-30 SK SK1077-2002A patent/SK10772002A3/sk not_active Application Discontinuation
-
2001
- 2001-01-08 GT GT200100005A patent/GT200100005A/es unknown
- 2001-01-22 SV SV2001000287A patent/SV2002000287A/es not_active Application Discontinuation
- 2001-01-24 PA PA20018510801A patent/PA8510801A1/es unknown
- 2001-01-24 HN HN2001000012A patent/HN2001000012A/es unknown
- 2001-01-25 AR ARP010100308A patent/AR029437A1/es unknown
- 2001-01-25 PE PE2001000082A patent/PE20011228A1/es not_active Application Discontinuation
- 2001-01-25 CO CO01005602A patent/CO5280216A1/es not_active Application Discontinuation
- 2001-01-26 TN TNTNSN01018A patent/TNSN01018A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
US20040224958A1 (en) | 2004-11-11 |
CA2394525A1 (en) | 2001-08-02 |
CN1433417A (zh) | 2003-07-30 |
AU1808601A (en) | 2001-08-07 |
PL357634A1 (en) | 2004-07-26 |
AR029437A1 (es) | 2003-06-25 |
JP2003523358A (ja) | 2003-08-05 |
KR20020070520A (ko) | 2002-09-09 |
WO2001055148A1 (en) | 2001-08-02 |
HN2001000012A (es) | 2001-07-09 |
CZ20022521A3 (cs) | 2003-02-12 |
CO5280216A1 (es) | 2003-05-30 |
SK10772002A3 (sk) | 2004-01-08 |
GT200100005A (es) | 2002-02-05 |
BR0017075A (pt) | 2002-11-05 |
HUP0203803A3 (en) | 2004-09-28 |
PE20011228A1 (es) | 2002-01-18 |
EP1255755A1 (en) | 2002-11-13 |
TNSN01018A1 (en) | 2005-11-10 |
HUP0203803A2 (hu) | 2003-02-28 |
PA8510801A1 (es) | 2002-12-11 |
IL150742A0 (en) | 2003-02-12 |
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