ATE356124T1 - Hydroxyalkylsubstituierte pyrido-7-pyrimidin-7- one - Google Patents
Hydroxyalkylsubstituierte pyrido-7-pyrimidin-7- oneInfo
- Publication number
- ATE356124T1 ATE356124T1 AT04797601T AT04797601T ATE356124T1 AT E356124 T1 ATE356124 T1 AT E356124T1 AT 04797601 T AT04797601 T AT 04797601T AT 04797601 T AT04797601 T AT 04797601T AT E356124 T1 ATE356124 T1 AT E356124T1
- Authority
- AT
- Austria
- Prior art keywords
- pyrimidine
- hydroxyalkyl substituted
- substituted pyrido
- pyrido
- hydroxyalkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51978903P | 2003-11-13 | 2003-11-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE356124T1 true ATE356124T1 (de) | 2007-03-15 |
Family
ID=34590444
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04797601T ATE356124T1 (de) | 2003-11-13 | 2004-11-04 | Hydroxyalkylsubstituierte pyrido-7-pyrimidin-7- one |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US7348331B2 (de) |
| EP (1) | EP1685131B1 (de) |
| JP (1) | JP4616839B2 (de) |
| KR (1) | KR100816321B1 (de) |
| CN (1) | CN100455582C (de) |
| AR (1) | AR046705A1 (de) |
| AT (1) | ATE356124T1 (de) |
| AU (1) | AU2004289428B2 (de) |
| BR (1) | BRPI0416030A (de) |
| CA (1) | CA2544247A1 (de) |
| CO (1) | CO5690600A2 (de) |
| DE (1) | DE602004005238T2 (de) |
| DK (1) | DK1685131T3 (de) |
| ES (1) | ES2281843T3 (de) |
| HR (1) | HRP20070132T3 (de) |
| IL (1) | IL175284A0 (de) |
| MY (1) | MY141011A (de) |
| NO (1) | NO20062256L (de) |
| NZ (1) | NZ546634A (de) |
| PL (1) | PL1685131T3 (de) |
| PT (1) | PT1685131E (de) |
| RU (1) | RU2348632C2 (de) |
| SI (1) | SI1685131T1 (de) |
| TW (1) | TWI349670B (de) |
| WO (1) | WO2005047284A1 (de) |
| ZA (1) | ZA200603829B (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2656507C (en) | 2006-07-17 | 2012-03-20 | Amgen Inc. | Quinazoline and pyridopyrimidine derivatives as p38 kinase inhibitors |
| JP2010513382A (ja) * | 2006-12-22 | 2010-04-30 | エフ．ホフマン−ラ ロシュ アーゲー | アミノ−アルキレンジオール合成のための化合物及び方法 |
| CN101679211A (zh) * | 2007-06-15 | 2010-03-24 | 霍夫曼-拉罗奇有限公司 | 用于制备3-氨基-戊-1,5-二醇的新方法 |
| KR101754664B1 (ko) * | 2009-12-18 | 2017-07-06 | 템플 유니버시티-오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 | 치환된 피리도〔2,3-ｄ〕피리미딘-7(8ｈ)-온스 및 이의 치료 용도 |
| KR102046448B1 (ko) | 2014-02-07 | 2019-11-19 | 프린시피아 바이오파마, 인코퍼레이티드 | 섬유모세포 성장 인자 수용체 저해제로서 퀴놀론 유도체들 |
| WO2017027567A1 (en) | 2015-08-11 | 2017-02-16 | Principia Biopharma, Inc. | Processes for preparing an fgfr inhibitor |
| CN105418609B (zh) * | 2015-12-31 | 2017-06-23 | 山东大学 | 4‑(1,2,3‑三氮唑取代苯胺基)‑吡啶骈嘧啶酮衍生物及其制备方法与应用 |
| WO2017151409A1 (en) | 2016-02-29 | 2017-09-08 | University Of Florida Research Foundation, Incorporated | Chemotherapeutic methods |
| MY194619A (en) | 2016-06-02 | 2022-12-07 | Abbvie Inc | Glucocorticoid receptor agonist and immunoconjugates thereof |
| SG11201809882XA (en) | 2016-06-08 | 2018-12-28 | Support Venture Gmbh | Pharmaceutical combinations for treating cancer |
| CN109562105A (zh) | 2016-08-17 | 2019-04-02 | 企业支持有限责任公司 | 预防或治疗听力损失的方法 |
| SG10202110804WA (en) * | 2017-04-04 | 2021-11-29 | Kinarus Ag | Methods of preventing or treating ophthalmic diseases |
| EP3692144A1 (de) | 2017-10-05 | 2020-08-12 | Fulcrum Therapeutics, Inc. | Verwendung von p38-inhibitoren zur verringerung der expression von dux4 |
| US10342786B2 (en) | 2017-10-05 | 2019-07-09 | Fulcrum Therapeutics, Inc. | P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD |
| BR112020010694A2 (pt) | 2017-12-01 | 2020-11-10 | Abbvie Inc. | agonista de receptor de glicocorticoides e imunoconjugados do mesmo |
| JP7304896B2 (ja) | 2018-05-21 | 2023-07-07 | ネルビアーノ・メデイカル・サイエンシーズ・エツセ・エルレ・エルレ | 複素縮合ピリドン化合物及びｉｄｈ阻害剤としてのこれらの使用 |
| CN112512586A (zh) | 2018-07-13 | 2021-03-16 | 基纳鲁斯股份公司 | 用于预防或治疗纤维化疾病的ppar激动剂和p38激酶抑制剂的组合 |
| WO2021089395A1 (en) | 2019-11-08 | 2021-05-14 | Nerviano Medical Sciences S.R.L. | Gem-disubstituted heterocyclic compounds and their use as idh inhibitors |
| WO2022034031A1 (en) | 2020-08-11 | 2022-02-17 | Kinarus Ag | Methods of preventing or treating covid-19 and related viral diseases or disorders |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4215216A (en) * | 1979-04-18 | 1980-07-29 | American Home Products Corporation | 7,8-Dihydro-2,5,8-trisubstituted-7-oxo-pyrido[2,3-d]pyrimidine-6-carboxylic acid derivatives |
| US5037826A (en) * | 1986-10-15 | 1991-08-06 | Schering Corporation | 1-substituted naphthyridine and pyridopyrazine derivatives |
| EP0278686A1 (de) | 1987-02-07 | 1988-08-17 | The Wellcome Foundation Limited | Pyridopyrimidine, Verfahren zu ihrer Herstellung und pharmazeutische Zubereitungen davon |
| US5149699A (en) * | 1991-10-24 | 1992-09-22 | American Home Products Corporation | Substituted pyridopyrimidines useful as antgiotensin II antagonists |
| WO1993017682A1 (en) | 1992-03-04 | 1993-09-16 | Abbott Laboratories | Angiotensin ii receptor antagonists |
| IL115256A0 (en) * | 1994-11-14 | 1995-12-31 | Warner Lambert Co | 6-Aryl pyrido (2,3-d) pyrimidines and naphthyridines and their use |
| ES2146782T3 (es) | 1994-11-14 | 2000-08-16 | Warner Lambert Co | 6-aril-pirido(2,3-d)pirimidinas y naftiridinas para la inhibicion de la proliferacion celular inducida por la proteina tirosina quinasa. |
| US5620981A (en) * | 1995-05-03 | 1997-04-15 | Warner-Lambert Company | Pyrido [2,3-D]pyrimidines for inhibiting protein tyrosine kinase mediated cellular proliferation |
| IL117923A (en) | 1995-05-03 | 2000-06-01 | Warner Lambert Co | Anti-cancer pharmaceutical compositions containing polysubstituted pyrido¬2,3-d¾pyrimidine derivatives and certain such novel compounds |
| ES2301194T3 (es) | 1997-02-05 | 2008-06-16 | Warner-Lambert Company Llc | Pirido 2,3-d pirimidinas y 4-aminopirimidinas como inhibidores de la proliferacion celular. |
| US5945422A (en) * | 1997-02-05 | 1999-08-31 | Warner-Lambert Company | N-oxides of amino containing pyrido 2,3-D! pyrimidines |
| CN1138778C (zh) | 1998-05-26 | 2004-02-18 | 沃尼尔·朗伯公司 | 用作细胞增殖抑制剂的二环嘧啶及二环3,4-二氢嘧啶化合物及用途 |
| US7053070B2 (en) * | 2000-01-25 | 2006-05-30 | Warner-Lambert Company | Pyrido[2,3-d]pyrimidine-2,7-diamine kinase inhibitors |
| EP1255755A1 (de) | 2000-01-27 | 2002-11-13 | Warner-Lambert Company | Pyridopyrimidinon derivate zur behandlung von neurodegenerativen erkrankungen |
| DZ3308A1 (de) | 2000-03-06 | 2001-09-27 | Warner Lambert Co | 5-alkylpyrido [2,3-d] pyrimidin tyrosine kinase inhibitoren |
| US6518276B2 (en) * | 2000-08-31 | 2003-02-11 | Syntex (U.S.A.) Llc | 7-oxo-pyridopyrimidines (II) |
| JP4141830B2 (ja) * | 2000-08-31 | 2008-08-27 | エフ．ホフマン−ラ ロシュ アーゲー | 細胞増殖の阻害剤としての７−オキソ−ピリドピリミジン類 |
| ATE305303T1 (de) * | 2001-02-12 | 2005-10-15 | Hoffmann La Roche | 6-substituierte pyridopyrimidine |
| GEP20063909B (en) * | 2002-01-22 | 2006-08-25 | Warner Lambert Co | 2-(PYRIDIN-2-YLAMINO)-PYRIDO[2,3d] PYRIMIDIN-7-ONES |
| FR2897336B1 (fr) | 2006-02-10 | 2010-07-30 | Ranger France | Support d'aile pour vehicule automobile |
-
2004
- 2004-11-04 SI SI200430261T patent/SI1685131T1/sl unknown
- 2004-11-04 EP EP04797601A patent/EP1685131B1/de not_active Expired - Lifetime
- 2004-11-04 DK DK04797601T patent/DK1685131T3/da active
- 2004-11-04 JP JP2006538744A patent/JP4616839B2/ja not_active Expired - Fee Related
- 2004-11-04 DE DE602004005238T patent/DE602004005238T2/de not_active Expired - Lifetime
- 2004-11-04 ES ES04797601T patent/ES2281843T3/es not_active Expired - Lifetime
- 2004-11-04 PL PL04797601T patent/PL1685131T3/pl unknown
- 2004-11-04 HR HR20070132T patent/HRP20070132T3/xx unknown
- 2004-11-04 AU AU2004289428A patent/AU2004289428B2/en not_active Ceased
- 2004-11-04 PT PT04797601T patent/PT1685131E/pt unknown
- 2004-11-04 AT AT04797601T patent/ATE356124T1/de active
- 2004-11-04 RU RU2006120486/04A patent/RU2348632C2/ru not_active IP Right Cessation
- 2004-11-04 BR BRPI0416030-4A patent/BRPI0416030A/pt not_active IP Right Cessation
- 2004-11-04 WO PCT/EP2004/012475 patent/WO2005047284A1/en not_active Ceased
- 2004-11-04 KR KR1020067009146A patent/KR100816321B1/ko not_active Expired - Fee Related
- 2004-11-04 CA CA002544247A patent/CA2544247A1/en not_active Abandoned
- 2004-11-04 NZ NZ546634A patent/NZ546634A/en not_active IP Right Cessation
- 2004-11-04 CN CNB2004800337221A patent/CN100455582C/zh not_active Expired - Fee Related
- 2004-11-09 MY MYPI20044668A patent/MY141011A/en unknown
- 2004-11-10 AR ARP040104138A patent/AR046705A1/es not_active Application Discontinuation
- 2004-11-10 TW TW093134375A patent/TWI349670B/zh not_active IP Right Cessation
- 2004-11-12 US US10/987,656 patent/US7348331B2/en not_active Expired - Fee Related
-
2006
- 2006-04-27 IL IL175284A patent/IL175284A0/en unknown
- 2006-05-12 ZA ZA200603829A patent/ZA200603829B/en unknown
- 2006-05-12 CO CO06045585A patent/CO5690600A2/es not_active Application Discontinuation
- 2006-05-19 NO NO20062256A patent/NO20062256L/no not_active Application Discontinuation
-
2007
- 2007-11-19 US US11/985,821 patent/US7750016B2/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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