NO20062256L - Hydroksyalkylsubstituerte pyrido-7-pyrimidin-7-oner - Google Patents

Hydroksyalkylsubstituerte pyrido-7-pyrimidin-7-oner

Info

Publication number
NO20062256L
NO20062256L NO20062256A NO20062256A NO20062256L NO 20062256 L NO20062256 L NO 20062256L NO 20062256 A NO20062256 A NO 20062256A NO 20062256 A NO20062256 A NO 20062256A NO 20062256 L NO20062256 L NO 20062256L
Authority
NO
Norway
Prior art keywords
pyrimidin
hydroxyalkyl
ones
substituted pyrido
formula
Prior art date
Application number
NO20062256A
Other languages
English (en)
Norwegian (no)
Inventor
David Michael Goldstein
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO20062256L publication Critical patent/NO20062256L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO20062256A 2003-11-13 2006-05-19 Hydroksyalkylsubstituerte pyrido-7-pyrimidin-7-oner NO20062256L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51978903P 2003-11-13 2003-11-13
PCT/EP2004/012475 WO2005047284A1 (en) 2003-11-13 2004-11-04 Hydroxyalkyl substituted pyrido-7-pyrimidin-7-ones

Publications (1)

Publication Number Publication Date
NO20062256L true NO20062256L (no) 2006-06-06

Family

ID=34590444

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20062256A NO20062256L (no) 2003-11-13 2006-05-19 Hydroksyalkylsubstituerte pyrido-7-pyrimidin-7-oner

Country Status (27)

Country Link
US (2) US7348331B2 (de)
EP (1) EP1685131B1 (de)
JP (1) JP4616839B2 (de)
KR (1) KR100816321B1 (de)
CN (1) CN100455582C (de)
AR (1) AR046705A1 (de)
AT (1) ATE356124T1 (de)
AU (1) AU2004289428B2 (de)
BR (1) BRPI0416030A (de)
CA (1) CA2544247A1 (de)
CO (1) CO5690600A2 (de)
DE (1) DE602004005238T2 (de)
DK (1) DK1685131T3 (de)
ES (1) ES2281843T3 (de)
HK (1) HK1099021A1 (de)
HR (1) HRP20070132T3 (de)
IL (1) IL175284A0 (de)
MY (1) MY141011A (de)
NO (1) NO20062256L (de)
NZ (1) NZ546634A (de)
PL (1) PL1685131T3 (de)
PT (1) PT1685131E (de)
RU (1) RU2348632C2 (de)
SI (1) SI1685131T1 (de)
TW (1) TWI349670B (de)
WO (1) WO2005047284A1 (de)
ZA (1) ZA200603829B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7935709B2 (en) 2006-07-17 2011-05-03 Amgen Inc. 2-quinazolinone compounds and methods of use
EP2097370A2 (de) * 2006-12-22 2009-09-09 F. Hoffmann-Roche AG Verbindungen und verfahren zur synthese von amino-alkylendiol
CA2690327A1 (en) * 2007-06-15 2008-12-18 Thomas P. Cleary A novel process for the preparation of 3-amino-pentan-1,5-diol
US8889696B2 (en) * 2009-12-18 2014-11-18 Temple University—Of the Commonwealth System of Higher Education Substituted pyrido[2,3-d]pyrimidin-7(8H)-ones and therapeutic uses thereof
DK3102577T3 (en) * 2014-02-07 2018-11-12 Principia Biopharma Inc QUINOLONDERIVATIVES AS FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS
JP6940480B2 (ja) 2015-08-11 2021-09-29 プリンシピア バイオファーマ インコーポレイテッド Fgfr阻害剤の合成方法
CN105418609B (zh) * 2015-12-31 2017-06-23 山东大学 4‑(1,2,3‑三氮唑取代苯胺基)‑吡啶骈嘧啶酮衍生物及其制备方法与应用
US20190060286A1 (en) 2016-02-29 2019-02-28 University Of Florida Research Foundation, Incorpo Chemotherapeutic Methods
AU2017274442B2 (en) 2016-06-02 2021-08-19 Abbvie Inc. Glucocorticoid receptor agonist and immunoconjugates thereof
HUE053648T2 (hu) 2016-06-08 2021-07-28 Support Venture Gmbh Gyógyászati kombinációk rák kezelésére
EP3500258A1 (de) 2016-08-17 2019-06-26 Support-Venture GmbH Verfahren zur vorbeugung oder behandlung von gehörverlust
SG10202110804WA (en) 2017-04-04 2021-11-29 Kinarus Ag Methods of preventing or treating ophthalmic diseases
US10342786B2 (en) 2017-10-05 2019-07-09 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
PT3691620T (pt) 2017-10-05 2022-10-06 Fulcrum Therapeutics Inc Os inibidores da quinase p38 reduzem a expressão de dux4 e genes a jusante para o tratamento de fshd
EP3884962A1 (de) 2017-12-01 2021-09-29 AbbVie Inc. Glucocorticoid-rezeptor-agonist und immunkonjugate davon
EP3797107B1 (de) 2018-05-21 2022-08-10 Nerviano Medical Sciences S.r.l. Heterokondensierte pyridonverbindungen und ihre verwendung als idh-inhibitoren
MA53114A (fr) 2018-07-13 2021-05-19 Kinarus Ag Combinaisons d'agonistes de ppar et d'inhibiteurs de kinase p38 pour prévenir ou traiter des maladies fibrotiques
US20230000871A1 (en) 2019-11-08 2023-01-05 Nerviano Medical Sciences S.R.L. Gem-disubstituted heterocyclic compounds and their use as idh inhibitors
US20230263803A1 (en) 2020-08-11 2023-08-24 Kinarus Ag Methods of preventing or treating covid-19 and related viral diseases or disorders

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4215216A (en) 1979-04-18 1980-07-29 American Home Products Corporation 7,8-Dihydro-2,5,8-trisubstituted-7-oxo-pyrido[2,3-d]pyrimidine-6-carboxylic acid derivatives
US5037826A (en) 1986-10-15 1991-08-06 Schering Corporation 1-substituted naphthyridine and pyridopyrazine derivatives
AU598093B2 (en) 1987-02-07 1990-06-14 Wellcome Foundation Limited, The Pyridopyrimidines, methods for their preparation and pharmaceutical formulations thereof
WO1993017682A1 (en) 1992-03-04 1993-09-16 Abbott Laboratories Angiotensin ii receptor antagonists
IL115256A0 (en) 1994-11-14 1995-12-31 Warner Lambert Co 6-Aryl pyrido (2,3-d) pyrimidines and naphthyridines and their use
ES2146782T3 (es) 1994-11-14 2000-08-16 Warner Lambert Co 6-aril-pirido(2,3-d)pirimidinas y naftiridinas para la inhibicion de la proliferacion celular inducida por la proteina tirosina quinasa.
IL117923A (en) 1995-05-03 2000-06-01 Warner Lambert Co Anti-cancer pharmaceutical compositions containing polysubstituted pyrido¬2,3-d¾pyrimidine derivatives and certain such novel compounds
US5620981A (en) 1995-05-03 1997-04-15 Warner-Lambert Company Pyrido [2,3-D]pyrimidines for inhibiting protein tyrosine kinase mediated cellular proliferation
ATE391719T1 (de) 1997-02-05 2008-04-15 Warner Lambert Co Pyrido (2,3-d) pyrimidine und 4-amino-primidine als inhibitoren der zellulären proliferation
US5945422A (en) 1997-02-05 1999-08-31 Warner-Lambert Company N-oxides of amino containing pyrido 2,3-D! pyrimidines
AU763839B2 (en) 1998-05-26 2003-07-31 Warner-Lambert Company Bicyclic pyrimidines and bicyclic 3,4-dihydropyrimidines as inhibitors of cellular proliferation
US7053070B2 (en) 2000-01-25 2006-05-30 Warner-Lambert Company Pyrido[2,3-d]pyrimidine-2,7-diamine kinase inhibitors
BR0017075A (pt) 2000-01-27 2002-11-05 Warner Lambert Co Derivados de piridopirimidinona para tratamento de doença neurodegenerativa
WO2001070741A1 (en) 2000-03-06 2001-09-27 Warner-Lambert Company 5-alkylpyrido[2,3-d]pyrimidines tyrosine kinase inhibitors
US6518276B2 (en) 2000-08-31 2003-02-11 Syntex (U.S.A.) Llc 7-oxo-pyridopyrimidines (II)
CA2420286A1 (en) * 2000-08-31 2002-03-07 F. Hoffmann-La Roche Ag 7-oxo pyridopyrimidines as inhibitors of a cellular proliferation
IL156872A0 (en) * 2001-02-12 2004-02-08 Hoffmann La Roche 6-substituted pyrido-pyrimidines
DK1470124T3 (da) * 2002-01-22 2006-04-18 Warner Lambert Co 2-(Pyridin-2-yl amino)-pyrido[2,3]pyrimidin-7-oner
FR2897336B1 (fr) 2006-02-10 2010-07-30 Ranger France Support d'aile pour vehicule automobile

Also Published As

Publication number Publication date
HRP20070132T3 (en) 2007-05-31
CA2544247A1 (en) 2005-05-26
TW200526657A (en) 2005-08-16
CN100455582C (zh) 2009-01-28
US7348331B2 (en) 2008-03-25
DE602004005238D1 (de) 2007-04-19
AU2004289428A1 (en) 2005-05-26
EP1685131A1 (de) 2006-08-02
PT1685131E (pt) 2007-05-31
HK1099021A1 (en) 2007-08-03
IL175284A0 (en) 2006-09-05
AR046705A1 (es) 2005-12-21
EP1685131B1 (de) 2007-03-07
CN1882585A (zh) 2006-12-20
JP2007510686A (ja) 2007-04-26
RU2006120486A (ru) 2008-01-20
DE602004005238T2 (de) 2007-11-08
KR100816321B1 (ko) 2008-03-24
US20050107408A1 (en) 2005-05-19
MY141011A (en) 2010-02-25
ZA200603829B (en) 2007-10-31
AU2004289428B2 (en) 2010-06-03
KR20060086417A (ko) 2006-07-31
BRPI0416030A (pt) 2007-01-02
RU2348632C2 (ru) 2009-03-10
US20080119497A1 (en) 2008-05-22
ATE356124T1 (de) 2007-03-15
WO2005047284A1 (en) 2005-05-26
NZ546634A (en) 2010-01-29
US7750016B2 (en) 2010-07-06
PL1685131T3 (pl) 2007-08-31
SI1685131T1 (sl) 2007-06-30
ES2281843T3 (es) 2007-10-01
TWI349670B (en) 2011-10-01
JP4616839B2 (ja) 2011-01-19
CO5690600A2 (es) 2006-10-31
DK1685131T3 (da) 2007-07-09

Similar Documents

Publication Publication Date Title
NO20062256L (no) Hydroksyalkylsubstituerte pyrido-7-pyrimidin-7-oner
DE60214703D1 (de) Thiazolverbindungen, die sich als inhibitoren von proteinkinasen eignen
NO20064000L (no) Heteroarylkoblede pyrazoloderivater
NO20056192L (no) Kapaseinhibitorer og anvendelse derav
NO20063479L (no) Fosfonater, monofosfonamidater og bis-fosfonamidater for behandling av virussykdommer
NO20062561L (no) Kinoliner nyttige for behandling av kardiovaskulaere sykdommer
NO20051100L (no) Pyrazolsammensetninger anvendelige som GSK-3-inhibitorer
ATE371656T1 (de) Heteroaryl-pyrimidinderivate als jak-inhibitoren
ATE440087T1 (de) 2,4-diaminopyrimidinderivate, die sich als inhibitoren von pkc-theta eignen
ATE454378T1 (de) Verbindungen, die sich als inhibitoren vonjak und anderen proteinkinasen eignen
NO20050828L (no) lndol-3-svovelderivater
NO20062335L (no) Nye diazaspiroalkaner og deres anvendelse i behandlingen av CCR8 medierte sykdommer
NO20054905L (no) 2-acylamino-4-fenyltiazolderivater, fremgangsmate for deres fremstilling og anvendelse av de samme som i terapeutika
WO2005046603A3 (en) Pyridine compounds
NO20045677L (no) Inhibitorer av JAK- og CDK2-proteinkinaser
NO20085373L (no) P38 inhibitorer, deres fremstilling og anvendelse
NO20061080L (no) Kondenserte pyramidinforbindelser som inhibitorer av spenningsstyrte ionekanaler
NO20062021L (no) Omleirede pentanoler, fremgangsmpte for fremstilling av dette, og deres anvendelse som antiflogistika
NO20060324L (no) [1,8]Naftyridin-2-oner og relaterte forbindelser for behandling av Schizofreni
NO20053470L (no) Triazolopyridaziner som proteinkinase-inhibitorer
ATE433447T1 (de) Pyrimiidinverbindungen
NO20070557L (no) Ftalazinderivater som PARP-inhibitorer
NO20070526L (no) Kinazolindionderivater som parp-inhibitorer
NO20066055L (no) Pyridinderivater
NO20032801L (no) Tiazolderivater for behandling av PPAR-relaterte forstyrrelser

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application