SV2002000287A - Uso de inhibidor de la quinasa dependiente de la ciclina para preparar una composicion farmaceutica util para tratar enfermedades neurodegenerativas - Google Patents
Uso de inhibidor de la quinasa dependiente de la ciclina para preparar una composicion farmaceutica util para tratar enfermedades neurodegenerativasInfo
- Publication number
- SV2002000287A SV2002000287A SV2001000287A SV2001000287A SV2002000287A SV 2002000287 A SV2002000287 A SV 2002000287A SV 2001000287 A SV2001000287 A SV 2001000287A SV 2001000287 A SV2001000287 A SV 2001000287A SV 2002000287 A SV2002000287 A SV 2002000287A
- Authority
- SV
- El Salvador
- Prior art keywords
- neurodegenerative diseases
- dependent kinase
- prepare
- pharmaceutical composition
- kinase inhibitor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
ESTA INVENCION PROPORCIONA UN METODO PARA TRATAR ENFERMEDADES NEURODEGENERATIVAS EN MAMIFEROS, QUE COMPRENDE ADMINISTRAR UNA CANTIDAD EFECTIVA DE UN INHIBIDOR DE LA QUINASA DEPENDIENTE DE CICLINA. UN METODO PREFERIDO USA INHIBIDORES DE LA CDK DE FORMULA I:VER FORMULA; Y DE LA FORMULA II: VER FORMULA; EN DONDE:W ES NH; S; SO O SO2,R1 INCLUYE FENILO Y FENILO SUSTITUIDO,R2 INCLUYE ALQUILO Y CICLOALQUILO,R3 INCLUYE ALQUILO E HIDROGENO,R8 Y R9 INCLUYEN HIDROGENO Y ALQUILO, YZ ES CARBOXI.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17840000P | 2000-01-27 | 2000-01-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
SV2002000287A true SV2002000287A (es) | 2002-01-08 |
Family
ID=22652409
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SV2001000287A SV2002000287A (es) | 2000-01-27 | 2001-01-22 | Uso de inhibidor de la quinasa dependiente de la ciclina para preparar una composicion farmaceutica util para tratar enfermedades neurodegenerativas |
Country Status (22)
Country | Link |
---|---|
US (1) | US20040224958A1 (es) |
EP (1) | EP1255755A1 (es) |
JP (1) | JP2003523358A (es) |
KR (1) | KR20020070520A (es) |
CN (1) | CN1433417A (es) |
AR (1) | AR029437A1 (es) |
AU (1) | AU1808601A (es) |
BR (1) | BR0017075A (es) |
CA (1) | CA2394525A1 (es) |
CO (1) | CO5280216A1 (es) |
CZ (1) | CZ20022521A3 (es) |
GT (1) | GT200100005A (es) |
HN (1) | HN2001000012A (es) |
HU (1) | HUP0203803A3 (es) |
IL (1) | IL150742A0 (es) |
PA (1) | PA8510801A1 (es) |
PE (1) | PE20011228A1 (es) |
PL (1) | PL357634A1 (es) |
SK (1) | SK10772002A3 (es) |
SV (1) | SV2002000287A (es) |
TN (1) | TNSN01018A1 (es) |
WO (1) | WO2001055148A1 (es) |
Families Citing this family (80)
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US7053070B2 (en) * | 2000-01-25 | 2006-05-30 | Warner-Lambert Company | Pyrido[2,3-d]pyrimidine-2,7-diamine kinase inhibitors |
US7235551B2 (en) | 2000-03-02 | 2007-06-26 | Smithkline Beecham Corporation | 1,5-disubstituted-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one compounds and their use in treating csbp/p38 kinase mediated diseases |
NZ524806A (en) | 2000-10-23 | 2006-03-31 | Smithkline Beecham Corp | Tri-substituted 8H-pyrido[2,3-d]pyrimidin-7-one compounds |
WO2002068419A1 (fr) * | 2001-02-26 | 2002-09-06 | Tanabe Seiyaku Co., Ltd. | Derive de pyridopyrimidine ou naphthyridine |
DE60216747T2 (de) | 2001-04-09 | 2007-10-04 | Novartis Vaccines and Diagnostics, Inc., Emeryville | Guanidinoverbindungen als melanocortin-4-rezeptor (mc4-r) agonisten |
US7105667B2 (en) | 2001-05-01 | 2006-09-12 | Bristol-Myers Squibb Co. | Fused heterocyclic compounds and use thereof |
PE20030008A1 (es) | 2001-06-19 | 2003-01-22 | Bristol Myers Squibb Co | Inhibidores duales de pde 7 y pde 4 |
JP2005500294A (ja) | 2001-06-19 | 2005-01-06 | ブリストル−マイヤーズ スクイブ カンパニー | ホスホジエステラーゼ7に対するピリミジン阻害剤 |
EP1453516A2 (de) | 2001-10-17 | 2004-09-08 | Boehringer Ingelheim Pharma GmbH & Co.KG | 5-substituierte 4-amino-2-phenylamino-pyrimdinderivate und ihre verwendung als beta-amyloid modulatoren |
JP4460292B2 (ja) | 2001-10-17 | 2010-05-12 | ベーリンガー インゲルハイム ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト | ピリミジン誘導体、これらの化合物を含む医薬組成物、その使用及びその調製方法 |
KR20060111716A (ko) | 2002-01-22 | 2006-10-27 | 워너-램버트 캄파니 엘엘씨 | 2-(피리딘-2-일아미노)-피리도[2,3-d]피리미딘-7-온 |
RU2004133811A (ru) * | 2002-04-19 | 2005-04-20 | Смитклайн Бичам Корпорейшн (US) | Новые соединения |
WO2004043367A2 (en) | 2002-11-06 | 2004-05-27 | Bristol-Myers Squibb Company | Fused heterocyclic compounds and use thereof |
CA2502970A1 (en) * | 2002-11-28 | 2004-06-10 | Schering Aktiengesellschaft | Chk-, pdk- and akt-inhibitory pyrimidines, their production and use as pharmaceutical agents |
US7157455B2 (en) * | 2003-02-10 | 2007-01-02 | Hoffmann-La Roche Inc. | 4-Aminopyrimidine-5-one derivatives |
CA2523261C (en) | 2003-05-05 | 2009-07-07 | F. Hoffmann-La Roche Ag | Fused pyrimidine derivatives with crf activity |
DK1685131T3 (da) | 2003-11-13 | 2007-07-09 | Hoffmann La Roche | Hydroxyalkylsubstituerede pyrido-7-pyrimidin-7-oner |
PT1713806E (pt) * | 2004-02-14 | 2013-08-27 | Irm Llc | Compostos e composições como inibidores da proteína quinase |
CA2555724A1 (en) * | 2004-02-18 | 2005-09-09 | Warner-Lambert Company Llc | 2-(pyridin-3-ylamino)-pyrido[2,3-d]pyrimidin-7-ones |
WO2006021547A1 (de) * | 2004-08-26 | 2006-03-02 | Boehringer Ingelheim International Gmbh | Pteridinone als plk (polo like kinase) inhibitoren |
CA2590294A1 (en) * | 2004-12-13 | 2006-06-22 | Sunesis Pharmaceuticals, Inc. | Pyrido pyrimidinones, dihydro pyrimido pyrimidinones and pteridinones useful as raf kinase inhibitors |
PE20061193A1 (es) * | 2005-03-25 | 2006-12-02 | Glaxo Group Ltd | DERIVADOS DE 3,4-DIHIDROPIRIMIDO[4,5-d]PIRIMIDIN-2-[1H]-0NA COMO INHIBIDORES DE QUINASA p38 |
JP2008535822A (ja) * | 2005-03-25 | 2008-09-04 | グラクソ グループ リミテッド | 新規化合物 |
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CN102746298A (zh) | 2005-10-07 | 2012-10-24 | 埃克塞里艾克西斯公司 | PI3Kα的吡啶并嘧啶酮抑制剂 |
KR101099926B1 (ko) | 2006-09-15 | 2011-12-28 | 화이자 프로덕츠 인코포레이티드 | 피리도 (2,3-d) 피리미디논 화합물 및 이의 pi3 억제제로서의 용도 |
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US11628162B2 (en) | 2019-03-08 | 2023-04-18 | Incyte Corporation | Methods of treating cancer with an FGFR inhibitor |
WO2020205560A1 (en) | 2019-03-29 | 2020-10-08 | Incyte Corporation | Sulfonylamide compounds as cdk2 inhibitors |
JP2022533182A (ja) * | 2019-05-16 | 2022-07-21 | ユニバーシティー オブ ヒューストン システム | タンパク質キナーゼ阻害剤ならびに疾患および状態の治療のためのその使用 |
WO2021007269A1 (en) | 2019-07-09 | 2021-01-14 | Incyte Corporation | Bicyclic heterocycles as fgfr inhibitors |
WO2021072232A1 (en) | 2019-10-11 | 2021-04-15 | Incyte Corporation | Bicyclic amines as cdk2 inhibitors |
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-
2000
- 2000-11-30 JP JP2001561007A patent/JP2003523358A/ja active Pending
- 2000-11-30 IL IL15074200A patent/IL150742A0/xx unknown
- 2000-11-30 CN CN00818672A patent/CN1433417A/zh active Pending
- 2000-11-30 US US10/181,866 patent/US20040224958A1/en not_active Abandoned
- 2000-11-30 HU HU0203803A patent/HUP0203803A3/hu unknown
- 2000-11-30 EP EP00980883A patent/EP1255755A1/en not_active Withdrawn
- 2000-11-30 KR KR1020027009631A patent/KR20020070520A/ko not_active Application Discontinuation
- 2000-11-30 SK SK1077-2002A patent/SK10772002A3/sk not_active Application Discontinuation
- 2000-11-30 CA CA002394525A patent/CA2394525A1/en not_active Abandoned
- 2000-11-30 CZ CZ20022521A patent/CZ20022521A3/cs unknown
- 2000-11-30 BR BR0017075-5A patent/BR0017075A/pt not_active IP Right Cessation
- 2000-11-30 WO PCT/US2000/032572 patent/WO2001055148A1/en not_active Application Discontinuation
- 2000-11-30 PL PL00357634A patent/PL357634A1/xx not_active Application Discontinuation
- 2000-11-30 AU AU18086/01A patent/AU1808601A/en not_active Abandoned
-
2001
- 2001-01-08 GT GT200100005A patent/GT200100005A/es unknown
- 2001-01-22 SV SV2001000287A patent/SV2002000287A/es not_active Application Discontinuation
- 2001-01-24 HN HN2001000012A patent/HN2001000012A/es unknown
- 2001-01-24 PA PA20018510801A patent/PA8510801A1/es unknown
- 2001-01-25 CO CO01005602A patent/CO5280216A1/es not_active Application Discontinuation
- 2001-01-25 AR ARP010100308A patent/AR029437A1/es unknown
- 2001-01-25 PE PE2001000082A patent/PE20011228A1/es not_active Application Discontinuation
- 2001-01-26 TN TNTNSN01018A patent/TNSN01018A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
CO5280216A1 (es) | 2003-05-30 |
EP1255755A1 (en) | 2002-11-13 |
HUP0203803A2 (hu) | 2003-02-28 |
PL357634A1 (en) | 2004-07-26 |
HUP0203803A3 (en) | 2004-09-28 |
CA2394525A1 (en) | 2001-08-02 |
AU1808601A (en) | 2001-08-07 |
JP2003523358A (ja) | 2003-08-05 |
CZ20022521A3 (cs) | 2003-02-12 |
CN1433417A (zh) | 2003-07-30 |
PE20011228A1 (es) | 2002-01-18 |
SK10772002A3 (sk) | 2004-01-08 |
TNSN01018A1 (en) | 2005-11-10 |
IL150742A0 (en) | 2003-02-12 |
US20040224958A1 (en) | 2004-11-11 |
AR029437A1 (es) | 2003-06-25 |
KR20020070520A (ko) | 2002-09-09 |
GT200100005A (es) | 2002-02-05 |
PA8510801A1 (es) | 2002-12-11 |
HN2001000012A (es) | 2001-07-09 |
BR0017075A (pt) | 2002-11-05 |
WO2001055148A1 (en) | 2001-08-02 |
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