SU577982A3 - Способ получени 2-тетрагидрофурфурил6,7-бензоморфанов или их солей - Google Patents

Способ получени 2-тетрагидрофурфурил6,7-бензоморфанов или их солей

Info

Publication number
SU577982A3
SU577982A3 SU7502110984A SU2110984A SU577982A3 SU 577982 A3 SU577982 A3 SU 577982A3 SU 7502110984 A SU7502110984 A SU 7502110984A SU 2110984 A SU2110984 A SU 2110984A SU 577982 A3 SU577982 A3 SU 577982A3
Authority
SU
USSR - Soviet Union
Prior art keywords
mixture
mol
water
methanol
oxy
Prior art date
Application number
SU7502110984A
Other languages
English (en)
Russian (ru)
Inventor
Мерц Герберт
Лангбейн Адольф
Вальтер Герхард
Штокхаус Клаус
Original Assignee
К.Х.Берингер Зон (Фирма)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by К.Х.Берингер Зон (Фирма) filed Critical К.Х.Берингер Зон (Фирма)
Application granted granted Critical
Publication of SU577982A3 publication Critical patent/SU577982A3/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SU7502110984A 1974-03-09 1975-03-05 Способ получени 2-тетрагидрофурфурил6,7-бензоморфанов или их солей SU577982A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2411382A DE2411382C3 (de) 1974-03-09 1974-03-09 2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung

Publications (1)

Publication Number Publication Date
SU577982A3 true SU577982A3 (ru) 1977-10-25

Family

ID=5909593

Family Applications (3)

Application Number Title Priority Date Filing Date
SU7502110984A SU577982A3 (ru) 1974-03-09 1975-03-05 Способ получени 2-тетрагидрофурфурил6,7-бензоморфанов или их солей
SU752199295A SU588916A3 (ru) 1974-03-09 1975-12-19 Способ получени 2-тетрагидрофурил-6,7-бензоморфанов или их солей
SU7502199294A SU577983A3 (ru) 1974-03-09 1975-12-19 Способ получени 2-тетрагидрофурфурил-6,7-бензоморфанов или их солей, рацематов или оптически активных антиподов

Family Applications After (2)

Application Number Title Priority Date Filing Date
SU752199295A SU588916A3 (ru) 1974-03-09 1975-12-19 Способ получени 2-тетрагидрофурил-6,7-бензоморфанов или их солей
SU7502199294A SU577983A3 (ru) 1974-03-09 1975-12-19 Способ получени 2-тетрагидрофурфурил-6,7-бензоморфанов или их солей, рацематов или оптически активных антиподов

Country Status (25)

Country Link
JP (1) JPS5827275B2 (fr)
AT (1) AT344332B (fr)
BE (1) BE826440A (fr)
BG (3) BG24814A4 (fr)
CA (1) CA1049511A (fr)
CH (8) CH612425A5 (fr)
CS (1) CS188221B2 (fr)
DD (1) DD119236A5 (fr)
DE (1) DE2411382C3 (fr)
DK (1) DK137188C (fr)
ES (6) ES440345A1 (fr)
FI (1) FI63571C (fr)
FR (1) FR2262984B1 (fr)
GB (1) GB1496418A (fr)
HU (1) HU177408B (fr)
IE (1) IE40945B1 (fr)
IL (1) IL46760A (fr)
NL (1) NL7502724A (fr)
NO (1) NO141800C (fr)
PH (1) PH14127A (fr)
PL (3) PL93699B1 (fr)
RO (2) RO70051A (fr)
SE (1) SE421919B (fr)
SU (3) SU577982A3 (fr)
ZA (1) ZA751394B (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
JP3955093B2 (ja) * 1995-03-10 2007-08-08 フォトキュア エイエスエイ 光化学治療における光増感剤としての５−アミノレブリン酸のエステル
US6492420B2 (en) 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
ATE554078T1 (de) 2007-07-26 2012-05-15 Vitae Pharmaceuticals Inc Synthese von 11-beta-hydroxysteroid-dehydrogenase-1-hemmern
CL2008003407A1 (es) 2007-11-16 2010-01-11 Boehringer Ingelheim Int Compuestos derivados de aril- y heteroarilcarbonilo de heterobiciclo sustituido; composicion farmaceutica; procedimiento de preparacion; y su uso en el tratamiento y/o prevencion de trastornos metabolicos, mediado por la inhibicion de la enzima hsd-1.
WO2009075835A1 (fr) 2007-12-11 2009-06-18 Vitae Pharmaceutical, Inc Inhibiteurs cycliques d'urée de la 11-hydroxystéroïde déhydrogénase 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
US8592409B2 (en) 2008-01-24 2013-11-26 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11β-hydroxysteroid dehydrogenase 1
JP5730021B2 (ja) 2008-02-15 2015-06-03 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の阻害剤としてのシクロアルキルラクタム誘導体
EP2291370B1 (fr) 2008-05-01 2013-11-27 Vitae Pharmaceuticals, Inc. Inhibiteurs cycliques de la 11-bêta-hydroxystéroïde déhydrogénase 1
AR071236A1 (es) 2008-05-01 2010-06-02 Vitae Pharmaceuticals Inc Inhibidores ciclicos de la 11beta-hidroxiesteroide deshidrogenasa 1
AR071609A1 (es) 2008-05-01 2010-06-30 Vitae Pharmaceuticals Inc Inhibidores ciclicos de 11(beta) -hidroxiesteroide deshidrogenasa 1
CL2009001151A1 (es) 2008-05-13 2010-08-13 Boehringer Ingelheim Int Compuestos derivados de acidos carbociclicos aliciclicos de benzomorfanos, procedimiento de preparacion, composicion farmaceutica, utiles para tratar enfermedades influenciadas por la inhibicion de la enzima 11beta-hidroxiesteroide deshidrogenasa, como trastornos metabolicos.
WO2010010157A2 (fr) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh Inhibiteurs de la 11 bêta-hydroxystéroïde déshydrogénase 1
CA2730499A1 (fr) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh Inhibiteurs cycliques de la 11 beta-hydroxysteroide deshydrogenase 1
MA33216B1 (fr) 2009-04-30 2012-04-02 Boehringer Ingelheim Int Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
EP2440537A1 (fr) 2009-06-11 2012-04-18 Vitae Pharmaceuticals, Inc. Inhibiteurs cycliques de la 11-bêta-hydroxystéroïde déshydrogénase 1 basée sur la structure 1,3-oxazinan-2-one
TWI531571B (zh) 2009-11-06 2016-05-01 維它藥物公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜芳基羰基衍生物
EP2582698B1 (fr) 2010-06-16 2016-09-14 Vitae Pharmaceuticals, Inc. Hétérocycles à 5, 6 et 7 chaînons substitués, médicaments contenant ces composés et leur utilisation
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
WO2013025664A1 (fr) 2011-08-17 2013-02-21 Boehringer Ingelheim International Gmbh Dérivés d'indénopyridine

Also Published As

Publication number Publication date
IE40945L (en) 1975-09-09
ES440346A1 (es) 1977-03-01
IE40945B1 (en) 1979-09-12
RO69617A (fr) 1980-08-15
FI63571B (fi) 1983-03-31
ES440348A1 (es) 1977-06-01
CH622016A5 (en) 1981-03-13
CH622015A5 (en) 1981-03-13
DD119236A5 (fr) 1976-04-12
AU7894275A (en) 1976-09-16
SU588916A3 (ru) 1978-01-15
IL46760A (en) 1978-12-17
ES440350A1 (es) 1977-03-16
BG24813A4 (en) 1978-05-12
NO750773L (fr) 1975-09-10
HU177408B (en) 1981-10-28
DK92975A (fr) 1975-09-10
DK137188B (da) 1978-01-30
CA1049511A (fr) 1979-02-27
PL93699B1 (fr) 1977-06-30
CS188221B2 (en) 1979-02-28
CH622014A5 (en) 1981-03-13
FR2262984A1 (fr) 1975-10-03
SU577983A3 (ru) 1977-10-25
IL46760A0 (en) 1975-05-22
CH612425A5 (en) 1979-07-31
PL93499B1 (fr) 1977-05-30
BG25087A3 (en) 1978-07-12
RO70051A (fr) 1980-12-30
DE2411382B2 (de) 1979-01-18
ES440347A1 (es) 1977-06-01
DK137188C (da) 1978-07-03
NO141800C (no) 1980-06-04
BG24814A4 (en) 1978-05-12
CH620681A5 (en) 1980-12-15
JPS5827275B2 (ja) 1983-06-08
AT344332B (de) 1978-07-10
CH620440A5 (en) 1980-11-28
NO141800B (no) 1980-02-04
FI63571C (fi) 1983-07-11
DE2411382C3 (de) 1979-09-06
ATA153875A (de) 1977-11-15
CH622017A5 (en) 1981-03-13
ZA751394B (en) 1976-11-24
BE826440A (fr) 1975-09-08
FR2262984B1 (fr) 1978-07-28
NL7502724A (nl) 1975-09-11
PL93700B1 (fr) 1977-06-30
SE7502592L (fr) 1975-09-10
ES440349A1 (es) 1977-03-01
FI750652A (fr) 1975-09-10
JPS50123675A (fr) 1975-09-29
PH14127A (en) 1981-02-26
CH620439A5 (en) 1980-11-28
ES440345A1 (es) 1977-03-01
GB1496418A (en) 1977-12-30
SE421919B (sv) 1982-02-08
DE2411382A1 (de) 1975-09-18

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