SE421919B - Forfarande for framstellning av 2-tetrahydrofurfuryl-6,7-bensomorfaner - Google Patents

Forfarande for framstellning av 2-tetrahydrofurfuryl-6,7-bensomorfaner

Info

Publication number
SE421919B
SE421919B SE7502592A SE7502592A SE421919B SE 421919 B SE421919 B SE 421919B SE 7502592 A SE7502592 A SE 7502592A SE 7502592 A SE7502592 A SE 7502592A SE 421919 B SE421919 B SE 421919B
Authority
SE
Sweden
Prior art keywords
benzomorphanes
tetrahydrofurfuryl
preparing
procedure
Prior art date
Application number
SE7502592A
Other languages
English (en)
Swedish (sv)
Other versions
SE7502592L (fr
Inventor
H Merz
A Langbein
G Walther
K Stockhaus
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of SE7502592L publication Critical patent/SE7502592L/xx
Publication of SE421919B publication Critical patent/SE421919B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
SE7502592A 1974-03-09 1975-03-07 Forfarande for framstellning av 2-tetrahydrofurfuryl-6,7-bensomorfaner SE421919B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2411382A DE2411382C3 (de) 1974-03-09 1974-03-09 2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung

Publications (2)

Publication Number Publication Date
SE7502592L SE7502592L (fr) 1975-09-10
SE421919B true SE421919B (sv) 1982-02-08

Family

ID=5909593

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7502592A SE421919B (sv) 1974-03-09 1975-03-07 Forfarande for framstellning av 2-tetrahydrofurfuryl-6,7-bensomorfaner

Country Status (25)

Country Link
JP (1) JPS5827275B2 (fr)
AT (1) AT344332B (fr)
BE (1) BE826440A (fr)
BG (3) BG24814A4 (fr)
CA (1) CA1049511A (fr)
CH (8) CH612425A5 (fr)
CS (1) CS188221B2 (fr)
DD (1) DD119236A5 (fr)
DE (1) DE2411382C3 (fr)
DK (1) DK137188C (fr)
ES (6) ES440350A1 (fr)
FI (1) FI63571C (fr)
FR (1) FR2262984B1 (fr)
GB (1) GB1496418A (fr)
HU (1) HU177408B (fr)
IE (1) IE40945B1 (fr)
IL (1) IL46760A (fr)
NL (1) NL7502724A (fr)
NO (1) NO141800C (fr)
PH (1) PH14127A (fr)
PL (3) PL93499B1 (fr)
RO (2) RO69617A (fr)
SE (1) SE421919B (fr)
SU (3) SU577982A3 (fr)
ZA (1) ZA751394B (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
AU708076B2 (en) * 1995-03-10 1999-07-29 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6492420B2 (en) 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
JP5451611B2 (ja) 2007-07-26 2014-03-26 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１のサイクリックインヒビター
CA2704628C (fr) 2007-11-16 2016-11-29 Boehringer Ingelheim International Gmbh Derives aryl- et heteroarylcarbonyles de benzomorphanes et structures liees a ceux-ci, medicaments contenant de tels composes et leur utilisation
WO2009075835A1 (fr) 2007-12-11 2009-06-18 Vitae Pharmaceutical, Inc Inhibiteurs cycliques d'urée de la 11-hydroxystéroïde déhydrogénase 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
JP5490020B2 (ja) 2008-01-24 2014-05-14 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状カルバゼート及びセミカルバジドインヒビター
US8598160B2 (en) 2008-02-15 2013-12-03 Vitae Pharmaceuticals, Inc. Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
CL2009001058A1 (es) 2008-05-01 2010-09-10 Vitae Pharmaceuticals Inc Compuestos derivados de oxazinas sustituidas, inhibidores de la 11b-hidroxiesteroide deshidrogenasa de tipo-1; composicion farmaceutica; y uso del compuesto para inhibir la actividad de 11b-hsd1, como en el tratamiento de la diabetes, dislipidemia, hipertension, obesidad, cancer, glaucoma, entre otras.
JP5538365B2 (ja) 2008-05-01 2014-07-02 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状阻害剤
PL2300461T3 (pl) 2008-05-01 2013-09-30 Vitae Pharmaceuticals Inc Cykliczne inhibitory dehydrogenazy 11beta-hydroksysteroidów 1
US8765780B2 (en) 2008-05-13 2014-07-01 Boehringer Ingelheim International Gmbh Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
CA2729998A1 (fr) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh Inhibiteurs de la 11 beta-hydroxysteroide deshydrogenase 1
EP2687525B1 (fr) 2008-07-25 2015-09-23 Boehringer Ingelheim International GmbH Inhibiteurs cycliques de la 11-bêta-hydroxystéroïde déshydrogénase 1
UA109255C2 (ru) 2009-04-30 2015-08-10 Берінгер Інгельхайм Інтернешнл Гмбх Циклические ингибиторы 11бета-гидроксистероиддегидрогеназы 1
US8927539B2 (en) 2009-06-11 2015-01-06 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 based on the 1,3-oxazinan-2-one structure
AR078887A1 (es) 2009-11-06 2011-12-07 Boehringer Ingelheim Int Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina y composiciones farmaceuticas que los contienen.
JP5860042B2 (ja) 2010-06-16 2016-02-16 ヴァイティー ファーマシューティカルズ，インコーポレイテッド 置換５、６及び７員複素環、そのような化合物を含有する医薬及びそれらの使用
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
JP2014524438A (ja) 2011-08-17 2014-09-22 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング インデノピリジン誘導体

Also Published As

Publication number Publication date
FR2262984A1 (fr) 1975-10-03
ZA751394B (en) 1976-11-24
CA1049511A (fr) 1979-02-27
PL93700B1 (fr) 1977-06-30
ATA153875A (de) 1977-11-15
CH620439A5 (en) 1980-11-28
FI750652A (fr) 1975-09-10
IE40945B1 (en) 1979-09-12
HU177408B (en) 1981-10-28
SU588916A3 (ru) 1978-01-15
IE40945L (en) 1975-09-09
CH622014A5 (en) 1981-03-13
CH622017A5 (en) 1981-03-13
FR2262984B1 (fr) 1978-07-28
CH622015A5 (en) 1981-03-13
BE826440A (fr) 1975-09-08
JPS50123675A (fr) 1975-09-29
NO750773L (fr) 1975-09-10
SU577982A3 (ru) 1977-10-25
ES440348A1 (es) 1977-06-01
BG24814A4 (en) 1978-05-12
SU577983A3 (ru) 1977-10-25
CH612425A5 (en) 1979-07-31
CH620681A5 (en) 1980-12-15
DE2411382B2 (de) 1979-01-18
AU7894275A (en) 1976-09-16
ES440349A1 (es) 1977-03-01
CH620440A5 (en) 1980-11-28
DE2411382A1 (de) 1975-09-18
DK137188B (da) 1978-01-30
FI63571C (fi) 1983-07-11
GB1496418A (en) 1977-12-30
RO70051A (fr) 1980-12-30
ES440350A1 (es) 1977-03-16
RO69617A (fr) 1980-08-15
FI63571B (fi) 1983-03-31
NL7502724A (nl) 1975-09-11
DK92975A (fr) 1975-09-10
JPS5827275B2 (ja) 1983-06-08
IL46760A (en) 1978-12-17
CS188221B2 (en) 1979-02-28
DD119236A5 (fr) 1976-04-12
ES440346A1 (es) 1977-03-01
SE7502592L (fr) 1975-09-10
PH14127A (en) 1981-02-26
ES440347A1 (es) 1977-06-01
NO141800B (no) 1980-02-04
NO141800C (no) 1980-06-04
BG24813A4 (en) 1978-05-12
AT344332B (de) 1978-07-10
PL93699B1 (fr) 1977-06-30
ES440345A1 (es) 1977-03-01
IL46760A0 (en) 1975-05-22
PL93499B1 (fr) 1977-05-30
BG25087A3 (en) 1978-07-12
DK137188C (da) 1978-07-03
CH622016A5 (en) 1981-03-13
DE2411382C3 (de) 1979-09-06

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