SMT201800680T1 - Derivati eterociclici e biciclici come inibitori di irak4 - Google Patents

Derivati eterociclici e biciclici come inibitori di irak4

Info

Publication number
SMT201800680T1
SMT201800680T1 SM20180680T SMT201800680T SMT201800680T1 SM T201800680 T1 SMT201800680 T1 SM T201800680T1 SM 20180680 T SM20180680 T SM 20180680T SM T201800680 T SMT201800680 T SM T201800680T SM T201800680 T1 SMT201800680 T1 SM T201800680T1
Authority
SM
San Marino
Prior art keywords
bicyclic heterocyclyl
irak4 inhibitors
heterocyclyl derivatives
derivatives
irak4
Prior art date
Application number
SM20180680T
Other languages
English (en)
Italian (it)
Inventor
Venkateshwar Rao Gummadi
Susanta Samajdar
Original Assignee
Aurigene Discovery Tech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aurigene Discovery Tech Ltd filed Critical Aurigene Discovery Tech Ltd
Publication of SMT201800680T1 publication Critical patent/SMT201800680T1/it

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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    • C07D513/04—Ortho-condensed systems
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  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
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  • Hematology (AREA)
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  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
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  • Urology & Nephrology (AREA)
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  • Oncology (AREA)
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  • Pregnancy & Childbirth (AREA)
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SM20180680T 2014-01-13 2015-01-12 Derivati eterociclici e biciclici come inibitori di irak4 SMT201800680T1 (it)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IN158CH2014 2014-01-13
IN3000CH2014 2014-06-20
PCT/IB2015/050217 WO2015104688A1 (en) 2014-01-13 2015-01-12 Bicyclic heterocyclyl derivatives as irak4 inhibitors
EP15735499.4A EP3094329B1 (en) 2014-01-13 2015-01-12 Bicyclic heterocyclyl derivatives as irak4 inhibitors

Publications (1)

Publication Number Publication Date
SMT201800680T1 true SMT201800680T1 (it) 2019-01-11

Family

ID=53523587

Family Applications (3)

Application Number Title Priority Date Filing Date
SM20180680T SMT201800680T1 (it) 2014-01-13 2015-01-12 Derivati eterociclici e biciclici come inibitori di irak4
SM20240142T SMT202400142T1 (it) 2014-01-13 2015-01-12 Enantiomeri (r) e (s) di n-(5-(3-idrossipirrolidin-1-il)-2-morfolinoossazolo[4,5-b]piridin-6-il)-2-(2-metilpiridin-4-il)ossazolo-carbossammide in qualità di inibitori di irak4 per il trattamento di un cancro
SM20210063T SMT202100063T1 (it) 2014-01-13 2015-01-12 Metodo di preparazione di derivati di ossazolo [4, 5-b] piridina e tiazolo [4, 5-b] piridina come inibitori di irak4 per il trattamento del cancro

Family Applications After (2)

Application Number Title Priority Date Filing Date
SM20240142T SMT202400142T1 (it) 2014-01-13 2015-01-12 Enantiomeri (r) e (s) di n-(5-(3-idrossipirrolidin-1-il)-2-morfolinoossazolo[4,5-b]piridin-6-il)-2-(2-metilpiridin-4-il)ossazolo-carbossammide in qualità di inibitori di irak4 per il trattamento di un cancro
SM20210063T SMT202100063T1 (it) 2014-01-13 2015-01-12 Metodo di preparazione di derivati di ossazolo [4, 5-b] piridina e tiazolo [4, 5-b] piridina come inibitori di irak4 per il trattamento del cancro

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JP (7) JP6479850B2 (enExample)
KR (4) KR20250049413A (enExample)
CN (2) CN111362966B (enExample)
AU (6) AU2015205374B2 (enExample)
BR (1) BR112016016158B1 (enExample)
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DK (3) DK3805233T3 (enExample)
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ES (3) ES2975436T3 (enExample)
FI (1) FI3805233T3 (enExample)
HR (3) HRP20181795T1 (enExample)
HU (3) HUE041926T2 (enExample)
IL (7) IL311677B2 (enExample)
LT (3) LT3094329T (enExample)
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MY (1) MY197116A (enExample)
NZ (2) NZ760657A (enExample)
PH (2) PH12016501344A1 (enExample)
PL (3) PL3094329T3 (enExample)
PT (3) PT3805233T (enExample)
RS (3) RS65437B1 (enExample)
SG (2) SG11201605486WA (enExample)
SI (3) SI3466955T1 (enExample)
SM (3) SMT201800680T1 (enExample)
TR (1) TR201815683T4 (enExample)
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