EA038748B1 - Способ получения бициклических гетероциклических производных - Google Patents

Способ получения бициклических гетероциклических производных Download PDF

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Publication number
EA038748B1
EA038748B1 EA201891917A EA201891917A EA038748B1 EA 038748 B1 EA038748 B1 EA 038748B1 EA 201891917 A EA201891917 A EA 201891917A EA 201891917 A EA201891917 A EA 201891917A EA 038748 B1 EA038748 B1 EA 038748B1
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EA
Eurasian Patent Office
Prior art keywords
pyridin
oxazole
carboxamide
mmol
piperidin
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EA201891917A
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English (en)
Russian (ru)
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EA201891917A1 (ru
Inventor
Венкатешвар Рао Гуммади
Сусанта Самадждар
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Ориджин Дискавери Текнолоджиз Лимитед
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Publication of EA201891917A1 publication Critical patent/EA201891917A1/ru
Publication of EA038748B1 publication Critical patent/EA038748B1/ru

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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EA201891917A 2014-01-13 2015-01-12 Способ получения бициклических гетероциклических производных EA038748B1 (ru)

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IN158CH2014 2014-01-13
IN3000CH2014 2014-06-20

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EA201891917A1 EA201891917A1 (ru) 2019-02-28
EA038748B1 true EA038748B1 (ru) 2021-10-14

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EA201891917A EA038748B1 (ru) 2014-01-13 2015-01-12 Способ получения бициклических гетероциклических производных

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GB201311888D0 (en) 2013-07-03 2013-08-14 Glaxosmithkline Ip Dev Ltd Novel compounds
GB201311891D0 (en) 2013-07-03 2013-08-14 Glaxosmithkline Ip Dev Ltd Novel compound
SG11201605408RA (en) 2014-01-10 2016-07-28 Aurigene Discovery Tech Ltd Indazole compounds as irak4 inhibitors
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