SK404391A3 - 3-imidazolymethyl-1,2,3,9-tetrahydro-4h-carbazole-4-on derivatives, method of their preparation and pharmaceutical agents containing this agents - Google Patents

3-imidazolymethyl-1,2,3,9-tetrahydro-4h-carbazole-4-on derivatives, method of their preparation and pharmaceutical agents containing this agents Download PDF

Info

Publication number
SK404391A3
SK404391A3 SK4043-91A SK404391A SK404391A3 SK 404391 A3 SK404391 A3 SK 404391A3 SK 404391 A SK404391 A SK 404391A SK 404391 A3 SK404391 A3 SK 404391A3
Authority
SK
Slovakia
Prior art keywords
methyl
formula
tetrahydro
carbazol
compound
Prior art date
Application number
SK4043-91A
Other languages
English (en)
Slovak (sk)
Other versions
SK277923B6 (en
Inventor
Ian H Coates
David C Humber
James A Bell
George B Ewan
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848401888A external-priority patent/GB8401888D0/en
Priority claimed from GB848425959A external-priority patent/GB8425959D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of SK277923B6 publication Critical patent/SK277923B6/sk
Publication of SK404391A3 publication Critical patent/SK404391A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
SK4043-91A 1984-01-25 1991-12-23 3-imidazolymethyl-1,2,3,9-tetrahydro-4h-carbazole-4-on derivatives, method of their preparation and pharmaceutical agents containing this agents SK404391A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB848401888A GB8401888D0 (en) 1984-01-25 1984-01-25 Heterocyclic compounds
GB848425959A GB8425959D0 (en) 1984-10-15 1984-10-15 Heterocyclic compounds

Publications (2)

Publication Number Publication Date
SK277923B6 SK277923B6 (en) 1995-08-09
SK404391A3 true SK404391A3 (en) 1995-08-09

Family

ID=26287221

Family Applications (1)

Application Number Title Priority Date Filing Date
SK4043-91A SK404391A3 (en) 1984-01-25 1991-12-23 3-imidazolymethyl-1,2,3,9-tetrahydro-4h-carbazole-4-on derivatives, method of their preparation and pharmaceutical agents containing this agents

Country Status (29)

Country Link
KR (1) KR920003064B1 (de)
AT (1) AT392276B (de)
AU (1) AU579132B2 (de)
BE (1) BE901576A (de)
CA (1) CA1252793A (de)
CH (1) CH664152A5 (de)
CY (1) CY1479A (de)
CZ (1) CZ404391A3 (de)
DE (2) DE3502508A1 (de)
DK (1) DK169521B1 (de)
ES (3) ES8609309A1 (de)
FI (1) FI84349C (de)
FR (1) FR2561244B1 (de)
GB (1) GB2153821B (de)
GR (1) GR850219B (de)
HK (1) HK33189A (de)
HU (1) HU193592B (de)
IE (1) IE57809B1 (de)
IL (1) IL74165A (de)
IT (1) IT1182150B (de)
LU (2) LU88268I2 (de)
NL (2) NL190373C (de)
NO (2) NO164025C (de)
NZ (1) NZ210940A (de)
PH (1) PH22672A (de)
PT (1) PT79890B (de)
SE (1) SE460359B (de)
SG (1) SG7089G (de)
SK (1) SK404391A3 (de)

Families Citing this family (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4695578A (en) * 1984-01-25 1987-09-22 Glaxo Group Limited 1,2,3,9-tetrahydro-3-imidazol-1-ylmethyl-4H-carbazol-4-ones, composition containing them, and method of using them to treat neuronal 5HT function disturbances
EP0191562B1 (de) * 1985-01-23 1991-07-10 Glaxo Group Limited Tetrahydrocarbazolonderivate
DE201165T1 (de) * 1985-03-14 1989-04-20 Beecham Group P.L.C., Brentford, Gb Arzneimittel zur behandlung von emesis, anxietas und "irritable bowel syndrome".
US5578628A (en) * 1985-06-25 1996-11-26 Glaxo Group Limited Medicaments for the treatment of nausea and vomiting
GB8516083D0 (en) * 1985-06-25 1985-07-31 Glaxo Group Ltd Heterocyclic compounds
US5204356A (en) * 1985-07-24 1993-04-20 Glaxo Group Limited Treatment of anxiety
GB8518743D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Heterocyclic compounds
GB8518658D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Medicaments
GB8518741D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Process
GB8518742D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Process
GB8518745D0 (en) 1985-07-24 1985-08-29 Glaxo Group Ltd Heterocyclic compounds
GB8617994D0 (en) * 1986-07-23 1986-08-28 Glaxo Group Ltd Heterocyclic compounds
HU202108B (en) * 1986-07-30 1991-02-28 Sandoz Ag Process for producing pharmaceutical compositions containing serotonine antqgonistic derivatives of indol-carboxylic acid or imidazolyl-methyl-carbazol
AT396870B (de) * 1986-08-07 1993-12-27 Sandoz Ag Verfahren zur herstellung einer galenischen formulierung zur nasalen verabreichung von serotoninantagonisten
GB8623819D0 (en) * 1986-10-03 1986-11-05 Glaxo Group Ltd Heterocyclic compounds
GB8627909D0 (en) * 1986-11-21 1986-12-31 Glaxo Group Ltd Medicaments
WO1988003801A1 (en) * 1986-11-21 1988-06-02 Glaxo Group Limited Medicaments for treatment or prevention of withdrawal syndrome
US5202343A (en) * 1986-11-28 1993-04-13 Glaxo Group Limited Tricyclic ketones useful as HT3 -receptor antagonists
GB8812002D0 (en) * 1988-05-20 1988-06-22 Glaxo Group Ltd Chemical compounds
GB8628475D0 (en) * 1986-11-28 1987-01-07 Glaxo Group Ltd Medicaments
GR871809B (en) * 1986-11-28 1988-03-07 Glaxo Group Ltd Process for the preparation of tricyclic ketones
GB8630071D0 (en) * 1986-12-17 1987-01-28 Glaxo Group Ltd Medicaments
DE3788057T2 (de) * 1986-12-17 1994-03-03 Glaxo Group Ltd Verwendung von heterocyclischen Verbindungen zur Behandlung von Depressionen.
US5190954A (en) * 1986-12-17 1993-03-02 Glaxo Group Limited Methods for the treatment of cognitive disorders
PH25025A (en) * 1986-12-17 1991-01-28 Glaxo Group Ltd A method of treating dementia and other cognitive disorders using 1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1h-imidazol-1-yl)methyl)-4h-carbazol-4-one
US5200414A (en) * 1986-12-17 1993-04-06 Glaxo Group Limited Methods for the treatment of cognitive disorders
GB8630079D0 (en) * 1986-12-17 1987-01-28 Glaxo Group Ltd Medicaments
US4918080A (en) * 1987-04-14 1990-04-17 Glaxo Group Limited Imidazollyl containing ketone derivatives
EP0295836B1 (de) * 1987-06-16 1992-09-02 Btg International Limited Verwendung von Dioxopiperidin-Derivaten zur Herstellung eines topischen Präparates als Analgetika
DE3822792C2 (de) * 1987-07-11 1997-11-27 Sandoz Ag Neue Verwendung von 5HT¶3¶-Antagonisten
GB8723157D0 (en) * 1987-10-02 1987-11-04 Beecham Group Plc Compounds
JPH01258673A (ja) * 1987-10-22 1989-10-16 Glaxo Group Ltd ケトン誘導体
CA1304082C (en) * 1987-10-22 1992-06-23 Tetsuya Tahara Benzoxazine compounds and pharmaceutical use thereof
US5225431A (en) * 1987-10-23 1993-07-06 Burroughs Wellcome Co. Therapeutic substituted indole compounds and compositions thereof
GB8805269D0 (en) * 1988-03-04 1988-04-07 Glaxo Group Ltd Medicaments
JPH0249772A (ja) * 1988-04-07 1990-02-20 Glaxo Group Ltd イミダゾール誘導体
DK185489A (da) * 1988-04-22 1989-10-23 Duphar Int Res Imidazolylmethyl-cycloalkanoebaaindoloner, deres fremstilling og anvendelse
US4985422A (en) * 1988-04-27 1991-01-15 Glaxo Group Limited Lactam derivatives
GB8812636D0 (en) * 1988-05-27 1988-06-29 Glaxo Group Ltd Chemical compounds
AU627221B2 (en) * 1988-09-27 1992-08-20 Fujisawa Pharmaceutical Co., Ltd. Pyridoindole derivatives and processes for preparation thereof
US5173493A (en) * 1988-09-27 1992-12-22 Fujisawa Pharmaceutical Company, Ltd. Pyridoindole derivatives and processes for preparation thereof
US5290785A (en) * 1988-09-27 1994-03-01 Fujisawa Pharmaceutical Co., Ltd. Therapeutic agent for ischemic diseases
FR2639944B1 (fr) * 1988-12-06 1991-01-18 Adir Nouveaux derives de l'indole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US5223625A (en) * 1988-12-22 1993-06-29 Duphar International Research B.V. Annelated indolo [3,2,-C]lactams
CA2004911A1 (en) * 1988-12-22 1990-06-22 Mitsuaki Ohta 4,5,6,7-tetrahydrobenzimidazole derivatives
EP0377238A1 (de) * 1988-12-22 1990-07-11 Duphar International Research B.V Annelierte Indolo(3,2-c)-lactame
CA2012092A1 (en) * 1989-03-13 1990-09-13 Tadao Okegawa 5-ht3 receptor antagonist
CA2031214A1 (en) * 1989-04-21 1990-10-22 Alberto Azcona Therapeutic use of 5-ht receptor antagonists
GB8914804D0 (en) * 1989-06-28 1989-08-16 Glaxo Group Ltd Process
GB8917557D0 (en) * 1989-08-01 1989-09-13 Glaxo Group Ltd Medicaments
US5276050A (en) * 1989-08-01 1994-01-04 Glaxo Group Limited Medicaments
US5126343A (en) * 1989-09-11 1992-06-30 G. D. Searle & Co. N-azabicyclo [3.3.0]octane amides of aromatic acids
GB2236751B (en) 1989-10-14 1993-04-28 Wyeth John & Brother Ltd Heterocyclic compounds
GB8928837D0 (en) * 1989-12-21 1990-02-28 Beecham Group Plc Pharmaceuticals
US5187166A (en) * 1990-07-31 1993-02-16 Nisshin Flour Milling Co., Ltd. Azabicyclo derivatives and their use as antiemetics
EP1022025A3 (de) * 1991-06-26 2002-06-05 Sepracor, Inc. Verfahren und Zusammensetzungen zur Behandlung von Erbrechen, Übelkeit und anderen Störungen unter Verwendung von optisch reinem S(+)-ondansetron
JPH05310732A (ja) * 1992-03-12 1993-11-22 Mitsubishi Kasei Corp シンノリン−３−カルボン酸誘導体
ES2043535B1 (es) * 1992-03-13 1994-08-01 Vita Invest Sa Procedimiento para la obtencion de la 1,2,3,9-tetrahidro-9-metil-3-(2-metil-1h-imidazol-1-il)metil*-4h-carbazol-4-ona.
HU212934B (en) 1992-10-14 1996-12-30 Richter Gedeon Vegyeszet Process for producing novel alkoxalylated carbazolone derivatives
CA2106642C (en) * 1992-10-14 2005-08-16 Peter Bod Carbazolone derivatives and process for preparing the same
CA2157671A1 (en) * 1993-03-08 1994-09-15 Kiyotaka Katsuta Medicament for treating or preventing cerebrovascular diseases
GB9310756D0 (en) * 1993-05-25 1993-07-14 Glaxo Lab Sa Compositions
GB2325408B (en) * 1994-06-28 1999-01-27 Kenneth Francis Prendergast Chewing gum formulation comprising ondansetron
GB9423588D0 (en) * 1994-11-22 1995-01-11 Glaxo Wellcome Inc Compositions
AU702594B2 (en) * 1995-10-13 1999-02-25 Duphar International Research B.V. Process for the preparation of enantiomerically pure imidazolyl compounds
US6365743B1 (en) 1995-10-13 2002-04-02 Duphar International Research B.V. Process for the preparation of enantiomerically pure imidazolyl compounds
US5969137A (en) * 1996-09-19 1999-10-19 Virginia Commonwealth University Benzylamidine derivatives with serotonin receptor binding activity
US6548082B1 (en) 1999-03-01 2003-04-15 Sepracor Inc. Methods for treating apnea and apnea disorders using optically pure R(+) ondansetron
EP1207160A1 (de) * 2000-11-20 2002-05-22 Hanmi Pharm. Co., Ltd. Verfahren zur Herstellung von 1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)-methyl)-4H-carbazol-4-one
EP1499623B1 (de) 2002-04-29 2007-06-13 TEVA Gyógyszergyár Zártkörüen Müködö Részvénytársaság Verfahren zur herstellung von 1,2,3,9-tetrahydro-9-methyl-3-¬(2-methyl-1h-imidazol-1-yl)methyl|-4h-carbazol-4-on
FI6164U1 (fi) * 2003-01-09 2004-03-15 Synthon Bv Ondansetronmuotoja
GB2398071B (en) * 2003-01-24 2006-06-07 Synthon Bv Process for making ondansetron and intermediate thereof
ES2238001B1 (es) * 2004-01-21 2006-11-01 Vita Cientifica, S.L. Nuevas formas polimorficas de ondansetron, procedimientos para su preparacion, composiciones farmaceuticas que los contienen y su uso como aantiemeticos.
US7288660B2 (en) 2004-05-07 2007-10-30 Taro Pharmaceutical Industries Limited Process for preparing ondansetron hydrochloride dihydrate having a defined particle size
US20090170872A1 (en) * 2005-07-05 2009-07-02 Orchid Research Laboratories Limited Compounds and Their Pharmaceutical Use
WO2010133663A1 (en) 2009-05-20 2010-11-25 INSERM (Institut National de la Santé et de la Recherche Médicale) Serotonin 5-ht3 receptor antagonists for use in the treatment of lesional vestibular disorders
EP2253316B1 (de) 2009-05-20 2013-08-14 INSERM (Institut National de la Santé et de la Recherche Médicale) Serotonin-5-HT3-Rezeptorantagonisten zur Verwendung bei der Behandlung oder Prävention einer Innenohr-Pathologie mit Vestibularisdefiziten
CN115611864A (zh) * 2022-11-01 2023-01-17 常州兰陵制药有限公司 一种昂丹司琼类化合物及其制备方法与应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3740404A (en) * 1969-05-09 1973-06-19 American Cyanamid Co Piperidinomethylenedihydrocarbazolones
US3634420A (en) * 1969-05-09 1972-01-11 American Cyanamid Co 3(morpholinomethyl)-2 3-dihydro-carbazol-4(1h)-ones
EP0191562B1 (de) * 1985-01-23 1991-07-10 Glaxo Group Limited Tetrahydrocarbazolonderivate

Also Published As

Publication number Publication date
CZ404391A3 (en) 1993-04-14
NO1994022I1 (no) 1994-11-09
HU193592B (en) 1987-11-30
LU88268I2 (de) 1994-02-03
KR850005439A (ko) 1985-08-26
FI84349C (fi) 1991-11-25
FI850323A0 (fi) 1985-01-25
SK277923B6 (en) 1995-08-09
GB2153821B (en) 1988-01-20
ATA20485A (de) 1990-08-15
NL940009I1 (nl) 1994-07-18
AU579132B2 (en) 1988-11-17
BE901576A (fr) 1985-07-25
HK33189A (en) 1989-04-28
ES539852A0 (es) 1986-07-16
AU3809785A (en) 1985-08-01
NZ210940A (en) 1989-08-29
GR850219B (de) 1985-05-23
DE3502508C2 (de) 1990-05-03
CH664152A5 (fr) 1988-02-15
ES8609309A1 (es) 1986-07-16
ES8801247A1 (es) 1987-12-16
FI850323L (fi) 1985-07-26
NO850300L (no) 1985-07-26
NL940009I2 (nl) 1999-05-03
DK35785A (da) 1985-07-26
FR2561244B1 (fr) 1988-03-04
DE3502508A1 (de) 1985-08-14
SE8500368L (sv) 1985-07-26
CY1479A (en) 1989-07-21
SE460359B (sv) 1989-10-02
ES556101A0 (es) 1987-12-16
NL8500202A (nl) 1985-08-16
SE8500368D0 (sv) 1985-01-25
IT8547600A0 (it) 1985-01-25
CA1252793A (en) 1989-04-18
SG7089G (en) 1989-06-09
GB2153821A (en) 1985-08-29
PH22672A (en) 1988-11-14
DK169521B1 (da) 1994-11-21
DE19375046I2 (de) 2002-10-10
IE57809B1 (en) 1993-04-21
KR920003064B1 (ko) 1992-04-13
NL190373C (nl) 1994-02-01
LU85743A1 (fr) 1986-08-04
ES8708224A1 (es) 1987-10-01
IL74165A (en) 1988-11-15
FR2561244A1 (fr) 1985-09-20
NO164025B (no) 1990-05-14
AT392276B (de) 1991-02-25
IT1182150B (it) 1987-09-30
IE850187L (en) 1985-07-25
HUT37784A (en) 1986-02-28
ES548430A0 (es) 1987-10-01
GB8501889D0 (en) 1985-02-27
PT79890B (en) 1987-02-03
FI84349B (fi) 1991-08-15
NO164025C (no) 1990-08-22
PT79890A (en) 1985-02-01
NL190373B (nl) 1993-09-01
DK35785D0 (da) 1985-01-25

Similar Documents

Publication Publication Date Title
SK404391A3 (en) 3-imidazolymethyl-1,2,3,9-tetrahydro-4h-carbazole-4-on derivatives, method of their preparation and pharmaceutical agents containing this agents
EP0219193B1 (de) Tetrahydrocarbazolonderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
US4695578A (en) 1,2,3,9-tetrahydro-3-imidazol-1-ylmethyl-4H-carbazol-4-ones, composition containing them, and method of using them to treat neuronal 5HT function disturbances
BE1001004A4 (fr) Nouvelles cetones tricycliques utiles comme medicaments, procede et intermediaires pour leur preparation.
EP0210840B1 (de) Substituierte Imidazolylmethyltetrahydrocarbazolone
EP0191562B1 (de) Tetrahydrocarbazolonderivate
TW201125854A (en) 5-membered heterocycle-based p38 kinase inhibitors
SK404491A3 (en) Tricyclic lactam compounds, pharmaceutical compositions comprising same and their use
JPS63146874A (ja) インドール誘導体
EP0104522B1 (de) Pyrazolo(3,4-b)pyridinderivate und Verfahren zu ihrer Herstellung
EP0162695B1 (de) 6-Sauerstoffhaltige-1,3,4,5-Tetrahydrobenz(cd)indole-4-amine
PT94070A (pt) Processo para a preparacao de derivados de piperazina
DK170279B1 (da) 3-substituerede l-aminoalkyl-lH-indol-forbindelser, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indeholdende disse
JPH09501954A (ja) イミダゾ［５，１−ｃ］［１，４］ベンゾキサジン−１−オンのイミダゾリルアルキル誘導体およびそれらの製造法
HU188475B (en) Process for producing benzothiopyrano-pyridinones
US6127388A (en) Azetidine, pyrrolidine and piperidine derivatives as 5-HT1D receptor agonists
JP2941702B2 (ja) ５‐ｈｔ３レセプターにおいて５‐ｈｔの作用に拮抗するラクタム誘導体を含む医薬組成物
KR830001667B1 (ko) 페닐 퀴놀리지딘의 제조방법
JPH0378862B2 (de)
US5994374A (en) Substituted 1-indolylpropyl-4-benzyl-tetrahydropyridine derivatives
JPS5839682A (ja) ベンズアゼピン類
EP0345956B1 (de) Tricyclische Ketone
RU2067980C1 (ru) Производные лактама и фармацевтическая композиция, являющаяся антагонистом 5-окситраптамина /5-нт/ на 5- нт3 -рецепторах или их физиологически приемлемые соли и соловаты
EP0329905A1 (de) Verwendung von Chinolizin- und Chinolizinon-Derivaten zur Herstellung von Arzneimitteln zur Erhöhung der Magenbeweglichkeit
JPS61210083A (ja) 複素環式化合物