FI850323L - Heterocykliska kompositioner. - Google Patents

Heterocykliska kompositioner.

Info

Publication number
FI850323L
FI850323L FI850323A FI850323A FI850323L FI 850323 L FI850323 L FI 850323L FI 850323 A FI850323 A FI 850323A FI 850323 A FI850323 A FI 850323A FI 850323 L FI850323 L FI 850323L
Authority
FI
Finland
Prior art keywords
heterocyclis
composition
heterocyclis composition
Prior art date
Application number
FI850323A
Other languages
English (en)
Other versions
FI850323A0 (fi
FI84349C (fi
FI84349B (fi
Inventor
Ian Harold Coates
James Angus Bell
David Cedric Humber
George Blanch Ewan
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848401888A external-priority patent/GB8401888D0/en
Priority claimed from GB848425959A external-priority patent/GB8425959D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of FI850323A0 publication Critical patent/FI850323A0/fi
Publication of FI850323L publication Critical patent/FI850323L/fi
Application granted granted Critical
Publication of FI84349B publication Critical patent/FI84349B/fi
Publication of FI84349C publication Critical patent/FI84349C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
FI850323A 1984-01-25 1985-01-25 Foerfarande foer framstaellning av en farmakologiskt vaerdefull foerening. FI84349C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB848401888A GB8401888D0 (en) 1984-01-25 1984-01-25 Heterocyclic compounds
GB8401888 1984-01-25
GB848425959A GB8425959D0 (en) 1984-10-15 1984-10-15 Heterocyclic compounds
GB8425959 1984-10-15

Publications (4)

Publication Number Publication Date
FI850323A0 FI850323A0 (fi) 1985-01-25
FI850323L true FI850323L (fi) 1985-07-26
FI84349B FI84349B (fi) 1991-08-15
FI84349C FI84349C (fi) 1991-11-25

Family

ID=26287221

Family Applications (1)

Application Number Title Priority Date Filing Date
FI850323A FI84349C (fi) 1984-01-25 1985-01-25 Foerfarande foer framstaellning av en farmakologiskt vaerdefull foerening.

Country Status (29)

Country Link
KR (1) KR920003064B1 (fi)
AT (1) AT392276B (fi)
AU (1) AU579132B2 (fi)
BE (1) BE901576A (fi)
CA (1) CA1252793A (fi)
CH (1) CH664152A5 (fi)
CY (1) CY1479A (fi)
CZ (1) CZ404391A3 (fi)
DE (2) DE3502508A1 (fi)
DK (1) DK169521B1 (fi)
ES (3) ES8609309A1 (fi)
FI (1) FI84349C (fi)
FR (1) FR2561244B1 (fi)
GB (1) GB2153821B (fi)
GR (1) GR850219B (fi)
HK (1) HK33189A (fi)
HU (1) HU193592B (fi)
IE (1) IE57809B1 (fi)
IL (1) IL74165A (fi)
IT (1) IT1182150B (fi)
LU (2) LU88268I2 (fi)
NL (2) NL190373C (fi)
NO (2) NO164025C (fi)
NZ (1) NZ210940A (fi)
PH (1) PH22672A (fi)
PT (1) PT79890B (fi)
SE (1) SE460359B (fi)
SG (1) SG7089G (fi)
SK (1) SK404391A3 (fi)

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GB8623819D0 (en) * 1986-10-03 1986-11-05 Glaxo Group Ltd Heterocyclic compounds
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EP0317088A1 (en) * 1987-10-22 1989-05-24 Glaxo Group Limited Ketone derivatives
US5225431A (en) * 1987-10-23 1993-07-06 Burroughs Wellcome Co. Therapeutic substituted indole compounds and compositions thereof
GB8805269D0 (en) * 1988-03-04 1988-04-07 Glaxo Group Ltd Medicaments
US5116984A (en) * 1988-04-07 1992-05-26 Glaxo Group Limited Imidazole derivatives
DK185489A (da) * 1988-04-22 1989-10-23 Duphar Int Res Imidazolylmethyl-cycloalkanoebaaindoloner, deres fremstilling og anvendelse
EP0339959A3 (en) * 1988-04-27 1991-03-20 Glaxo Group Limited Lactam derivatives
GB8812636D0 (en) * 1988-05-27 1988-06-29 Glaxo Group Ltd Chemical compounds
AU627221B2 (en) * 1988-09-27 1992-08-20 Fujisawa Pharmaceutical Co., Ltd. Pyridoindole derivatives and processes for preparation thereof
US5290785A (en) * 1988-09-27 1994-03-01 Fujisawa Pharmaceutical Co., Ltd. Therapeutic agent for ischemic diseases
US5173493A (en) * 1988-09-27 1992-12-22 Fujisawa Pharmaceutical Company, Ltd. Pyridoindole derivatives and processes for preparation thereof
FR2639944B1 (fr) * 1988-12-06 1991-01-18 Adir Nouveaux derives de l'indole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CA2004911A1 (en) * 1988-12-22 1990-06-22 Mitsuaki Ohta 4,5,6,7-tetrahydrobenzimidazole derivatives
US5223625A (en) * 1988-12-22 1993-06-29 Duphar International Research B.V. Annelated indolo [3,2,-C]lactams
EP0377238A1 (en) * 1988-12-22 1990-07-11 Duphar International Research B.V New annelated indolo (3,2-c)-lactams
EP0392663A1 (en) * 1989-03-13 1990-10-17 Ono Pharmaceutical Co., Ltd. Carboline derivative as a 5-HT3 receptor antagonist
AU631632B2 (en) * 1989-04-21 1992-12-03 Novartis Ag Therapeutic use of 5-ht3 receptor antagonists
GB8914804D0 (en) * 1989-06-28 1989-08-16 Glaxo Group Ltd Process
GB8917557D0 (en) * 1989-08-01 1989-09-13 Glaxo Group Ltd Medicaments
US5276050A (en) * 1989-08-01 1994-01-04 Glaxo Group Limited Medicaments
US5126343A (en) * 1989-09-11 1992-06-30 G. D. Searle & Co. N-azabicyclo [3.3.0]octane amides of aromatic acids
GB2236751B (en) 1989-10-14 1993-04-28 Wyeth John & Brother Ltd Heterocyclic compounds
GB8928837D0 (en) * 1989-12-21 1990-02-28 Beecham Group Plc Pharmaceuticals
US5187166A (en) * 1990-07-31 1993-02-16 Nisshin Flour Milling Co., Ltd. Azabicyclo derivatives and their use as antiemetics
EP0591434A4 (en) * 1991-06-26 1994-09-14 Sepracor Inc Method and compositions for treating emesis, nausea and other disorders using optically pure r(+) ondansetron
JPH05310732A (ja) * 1992-03-12 1993-11-22 Mitsubishi Kasei Corp シンノリン−３−カルボン酸誘導体
ES2043535B1 (es) * 1992-03-13 1994-08-01 Vita Invest Sa Procedimiento para la obtencion de la 1,2,3,9-tetrahidro-9-metil-3-(2-metil-1h-imidazol-1-il)metil*-4h-carbazol-4-ona.
HU212934B (en) 1992-10-14 1996-12-30 Richter Gedeon Vegyeszet Process for producing novel alkoxalylated carbazolone derivatives
CA2106642C (en) * 1992-10-14 2005-08-16 Peter Bod Carbazolone derivatives and process for preparing the same
WO1994020102A2 (en) * 1993-03-08 1994-09-15 Fujisawa Pharmaceutical Co., Ltd. Medicament for treating or preventing cerebrovascular diseases
GB9310756D0 (en) * 1993-05-25 1993-07-14 Glaxo Lab Sa Compositions
GB2325408B (en) * 1994-06-28 1999-01-27 Kenneth Francis Prendergast Chewing gum formulation comprising ondansetron
GB9423588D0 (en) * 1994-11-22 1995-01-11 Glaxo Wellcome Inc Compositions
AU702594B2 (en) * 1995-10-13 1999-02-25 Duphar International Research B.V. Process for the preparation of enantiomerically pure imidazolyl compounds
US6365743B1 (en) 1995-10-13 2002-04-02 Duphar International Research B.V. Process for the preparation of enantiomerically pure imidazolyl compounds
US5969137A (en) * 1996-09-19 1999-10-19 Virginia Commonwealth University Benzylamidine derivatives with serotonin receptor binding activity
JP2002538102A (ja) 1999-03-01 2002-11-12 セプラコア インコーポレーテッド 光学的に純粋なｒ（＋）オンダンセトロンを使用する無呼吸および無呼吸障害の治療方法
EP1207160A1 (en) * 2000-11-20 2002-05-22 Hanmi Pharm. Co., Ltd. Process for the preparation of 1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)-methyl)-4H-carbazol-4-one
JP2005529142A (ja) 2002-04-29 2005-09-29 テバ ジョジセルジャール レースベニュタールシャシャーグ １，２，３，９−テトラヒドロ−９−メチル−３−［（２−メチル−１ｈ−イミダゾル−１−イル）メチル］−４ｈ−カルバゾル−４−オンの製造方法
FI6164U1 (fi) * 2003-01-09 2004-03-15 Synthon Bv Ondansetronmuotoja
GB2398071B (en) * 2003-01-24 2006-06-07 Synthon Bv Process for making ondansetron and intermediate thereof
ES2238001B1 (es) * 2004-01-21 2006-11-01 Vita Cientifica, S.L. Nuevas formas polimorficas de ondansetron, procedimientos para su preparacion, composiciones farmaceuticas que los contienen y su uso como aantiemeticos.
CA2565854A1 (en) 2004-05-07 2005-11-17 Taro Pharmaceutical Industries Ltd. Process for preparing ondansetron hydrochloride dihydrate having a defined particle size
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US3634420A (en) * 1969-05-09 1972-01-11 American Cyanamid Co 3(morpholinomethyl)-2 3-dihydro-carbazol-4(1h)-ones
AU583343B2 (en) * 1985-01-23 1989-04-27 Glaxo Group Limited Heterocyclic compounds

Also Published As

Publication number Publication date
CZ404391A3 (en) 1993-04-14
CY1479A (en) 1989-07-21
DE3502508C2 (fi) 1990-05-03
HUT37784A (en) 1986-02-28
BE901576A (fr) 1985-07-25
ATA20485A (de) 1990-08-15
SE8500368L (sv) 1985-07-26
NO850300L (no) 1985-07-26
PT79890A (en) 1985-02-01
DE3502508A1 (de) 1985-08-14
FI850323A0 (fi) 1985-01-25
IE850187L (en) 1985-07-25
FR2561244B1 (fr) 1988-03-04
GB8501889D0 (en) 1985-02-27
GR850219B (fi) 1985-05-23
ES8801247A1 (es) 1987-12-16
LU85743A1 (fr) 1986-08-04
SG7089G (en) 1989-06-09
DE19375046I2 (de) 2002-10-10
NZ210940A (en) 1989-08-29
SE460359B (sv) 1989-10-02
IL74165A (en) 1988-11-15
AU579132B2 (en) 1988-11-17
KR850005439A (ko) 1985-08-26
FR2561244A1 (fr) 1985-09-20
FI84349C (fi) 1991-11-25
NL940009I1 (nl) 1994-07-18
DK35785D0 (da) 1985-01-25
NO164025B (no) 1990-05-14
HU193592B (en) 1987-11-30
AU3809785A (en) 1985-08-01
PH22672A (en) 1988-11-14
NL190373C (nl) 1994-02-01
NL8500202A (nl) 1985-08-16
SK277923B6 (en) 1995-08-09
NL940009I2 (nl) 1999-05-03
ES539852A0 (es) 1986-07-16
CA1252793A (en) 1989-04-18
NO164025C (no) 1990-08-22
DK35785A (da) 1985-07-26
HK33189A (en) 1989-04-28
KR920003064B1 (ko) 1992-04-13
SK404391A3 (en) 1995-08-09
CH664152A5 (fr) 1988-02-15
IE57809B1 (en) 1993-04-21
ES8609309A1 (es) 1986-07-16
GB2153821A (en) 1985-08-29
ES8708224A1 (es) 1987-10-01
NL190373B (nl) 1993-09-01
IT1182150B (it) 1987-09-30
LU88268I2 (fi) 1994-02-03
SE8500368D0 (sv) 1985-01-25
PT79890B (en) 1987-02-03
FI84349B (fi) 1991-08-15
ES556101A0 (es) 1987-12-16
NO1994022I1 (no) 1994-11-09
AT392276B (de) 1991-02-25
DK169521B1 (da) 1994-11-21
GB2153821B (en) 1988-01-20
IT8547600A0 (it) 1985-01-25
ES548430A0 (es) 1987-10-01

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Legal Events

Date Code Title Description
ND Supplementary protection certificate (spc) granted
SPCG Supplementary protection certificate granted

Spc suppl protection certif: L59

Extension date: 20050223

FG Patent granted

Owner name: GLAXO GROUP LIMITED

MA Patent expired