SK332292A3 - Fumaric acid salts of 9,9-alkylen-3,7-diazabicyclo[3,3,1]nonane compounds, method for producing them and a medicament containing same - Google Patents

Fumaric acid salts of 9,9-alkylen-3,7-diazabicyclo[3,3,1]nonane compounds, method for producing them and a medicament containing same Download PDF

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Publication number
SK332292A3
SK332292A3 SK3322-92A SK332292A SK332292A3 SK 332292 A3 SK332292 A3 SK 332292A3 SK 332292 A SK332292 A SK 332292A SK 332292 A3 SK332292 A3 SK 332292A3
Authority
SK
Slovakia
Prior art keywords
fumaric acid
diazabicyclo
nonane
formula
acid salts
Prior art date
Application number
SK3322-92A
Other languages
English (en)
Slovak (sk)
Other versions
SK279519B6 (sk
Inventor
Uwe Schon
Walter Heitmann
Uwe Matzel
Original Assignee
Solvay Pharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharm Gmbh filed Critical Solvay Pharm Gmbh
Publication of SK279519B6 publication Critical patent/SK279519B6/sk
Publication of SK332292A3 publication Critical patent/SK332292A3/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/13—Dicarboxylic acids
    • C07C57/15—Fumaric acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SK3322-92A 1991-12-03 1992-11-05 Fumaric acid salts of 9,9-alkylen-3,7-diazabicyclo[3,3,1]nonane compounds, method for producing them and a medicament containing same SK332292A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4139763A DE4139763A1 (de) 1991-12-03 1991-12-03 Kristalline fumarsaure salze von 9,9-alkylen-3,7-diazabicyclononan-verbindungen und diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
SK279519B6 SK279519B6 (sk) 1998-12-02
SK332292A3 true SK332292A3 (en) 1998-12-02

Family

ID=6446125

Family Applications (1)

Application Number Title Priority Date Filing Date
SK3322-92A SK332292A3 (en) 1991-12-03 1992-11-05 Fumaric acid salts of 9,9-alkylen-3,7-diazabicyclo[3,3,1]nonane compounds, method for producing them and a medicament containing same

Country Status (25)

Country Link
US (1) US5324732A (no)
EP (1) EP0550383B1 (no)
JP (1) JP3180848B2 (no)
KR (1) KR100252389B1 (no)
CN (1) CN1040758C (no)
AT (1) ATE124411T1 (no)
AU (1) AU652869B2 (no)
CA (1) CA2084489C (no)
CZ (1) CZ281930B6 (no)
DE (2) DE4139763A1 (no)
DK (1) DK0550383T3 (no)
DZ (1) DZ1636A1 (no)
ES (1) ES2073900T3 (no)
FI (1) FI100053B (no)
HK (1) HK1006568A1 (no)
HU (3) HU9203698D0 (no)
IL (1) IL103819A (no)
LT (1) LTIP230A (no)
MX (1) MX9206988A (no)
NO (1) NO300687B1 (no)
NZ (1) NZ245227A (no)
PH (1) PH31114A (no)
SK (1) SK332292A3 (no)
TW (1) TW274084B (no)
ZA (1) ZA928863B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4421324A1 (de) * 1994-06-17 1995-12-21 Kali Chemie Pharma Gmbh Neue 3,7-Diazabicyclo [3,3,1] nonan-Verbindungen enthaltende Arzneimittel
JP5049450B2 (ja) * 2000-09-29 2012-10-17 アボツト・ヘルスケア・プロダクツ・ベー・ブイ イオン強度に依存しない徐放性製薬組成物
TW200418468A (en) * 2002-11-18 2004-10-01 Solvay Pharm Gmbh Liquid pharmaceutical formulations containing 3,7-diazabicyclo[3,3,1]nonane compounds and method of treatments relating to anti-arrhytmic events
US20050054667A1 (en) * 2003-07-21 2005-03-10 Solvay Pharmaceuticals Gmbh Method of treating or inhibiting anti-arrhythmic events in male human patients
EP1648456A1 (en) * 2003-07-21 2006-04-26 Solvay Pharmaceuticals GmbH Use of 3,7-diazabicyclo¬3,3,1|nonane compounds for the treatment and/or prophylaxis of arrhythmic events in male human patients
WO2005030207A1 (en) * 2003-09-26 2005-04-07 Solvay Pharmaceuticals Gmbh Use of 3, 7-diazabicyclo (3.3.1) nonane compounds for the treatment of brugada syndrome

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2551283C3 (de) * 1975-11-14 1981-02-19 Hokuriku Pharmaceutical Co., Ltd., Katsuyama, Fukui (Japan) Monofumarsäuresalz von 3-Pyridylmethylnikotinat und Verfahren zu seiner Herstellung
DE2658558A1 (de) * 1976-12-23 1978-06-29 Bayer Ag Diazabicyclo(3,3,1)nonane, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE3234697A1 (de) * 1982-09-18 1984-03-22 Kali-Chemie Pharma Gmbh, 3000 Hannover Neue diazabicyclo-(3,3,1)-nonane
PT88381B (pt) * 1987-09-09 1995-07-06 Kali Chemie Pharma Gmbh Processo para a preparacao de novos compostos 3,7-diazabiciclo{3,3,1} nonano, e de composicoes farmaceuticas que contem estes compostos
US4971992A (en) * 1989-03-27 1990-11-20 Hoechst-Roussel Pharmaceuticals Inc. Carbonate derivatives of eseroline
DE4019080A1 (de) * 1990-06-15 1991-12-19 Kali Chemie Pharma Gmbh Neue 3,7-diazabicycolo (3,3,1)nonan-verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
NO924647L (no) 1993-06-04
HK1006568A1 (en) 1999-03-05
US5324732A (en) 1994-06-28
LTIP230A (en) 1994-05-15
FI925482A0 (fi) 1992-12-02
SK279519B6 (sk) 1998-12-02
CN1040758C (zh) 1998-11-18
TW274084B (no) 1996-04-11
CN1072931A (zh) 1993-06-09
EP0550383B1 (de) 1995-06-28
CA2084489A1 (en) 1993-06-04
JP3180848B2 (ja) 2001-06-25
IL103819A (en) 1996-09-12
ES2073900T3 (es) 1995-08-16
AU652869B2 (en) 1994-09-08
AU2981592A (en) 1993-06-10
JPH05247040A (ja) 1993-09-24
IL103819A0 (en) 1993-04-04
DE4139763A1 (de) 1993-06-09
NO300687B1 (no) 1997-07-07
MX9206988A (es) 1993-06-01
NZ245227A (en) 1994-06-27
DZ1636A1 (fr) 2002-02-17
KR100252389B1 (ko) 2000-05-01
PH31114A (en) 1998-02-23
FI100053B (fi) 1997-09-15
DE59202726D1 (de) 1995-08-03
HUT63417A (en) 1993-08-30
CZ281930B6 (cs) 1997-04-16
HU210215A9 (en) 1995-02-28
HU213672B (en) 1997-09-29
CA2084489C (en) 2002-10-08
FI925482A (fi) 1993-06-04
ATE124411T1 (de) 1995-07-15
KR930012772A (ko) 1993-07-21
NO924647D0 (no) 1992-12-02
CZ332292A3 (en) 1993-08-11
ZA928863B (en) 1993-05-13
HU9203698D0 (en) 1993-03-29
DK0550383T3 (da) 1995-08-28
EP0550383A1 (de) 1993-07-07

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Legal Events

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TC4A Change of owner's name

Owner name: ABBOTT PRODUCTS GMBH, HANNOVER, DE

Effective date: 20120920

MK4A Patent expired

Expiry date: 20121105