SK287372B6 - Spôsob zvýšenia výťažku prostriedku obsahujúceho interferón-alfa - Google Patents

Spôsob zvýšenia výťažku prostriedku obsahujúceho interferón-alfa Download PDF

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Publication number
SK287372B6
SK287372B6 SK617-2001A SK6172001A SK287372B6 SK 287372 B6 SK287372 B6 SK 287372B6 SK 6172001 A SK6172001 A SK 6172001A SK 287372 B6 SK287372 B6 SK 287372B6
Authority
SK
Slovakia
Prior art keywords
protein
pyruvate
isoform
attached
isoforms
Prior art date
Application number
SK617-2001A
Other languages
English (en)
Slovak (sk)
Other versions
SK6172001A3 (en
Inventor
Susan Cannon-Carlson
Andreas Frei
Seoju Lee
Roland Mengisen
Marcio Voloch
David C. Wylie
Original Assignee
Schering Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corporation filed Critical Schering Corporation
Publication of SK6172001A3 publication Critical patent/SK6172001A3/sk
Publication of SK287372B6 publication Critical patent/SK287372B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SK617-2001A 1998-11-12 1999-10-05 Spôsob zvýšenia výťažku prostriedku obsahujúceho interferón-alfa SK287372B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19054298A 1998-11-12 1998-11-12
PCT/US1999/020900 WO2000029440A1 (en) 1998-11-12 1999-10-05 Methods of conversion of interferon isoforms and products thereof

Publications (2)

Publication Number Publication Date
SK6172001A3 SK6172001A3 (en) 2001-10-08
SK287372B6 true SK287372B6 (sk) 2010-08-09

Family

ID=22701766

Family Applications (2)

Application Number Title Priority Date Filing Date
SK5003-2010A SK287564B6 (sk) 1998-11-12 1999-10-05 Spôsob zvýšenia výťažku prostriedku obsahujúceho interferón-alfa
SK617-2001A SK287372B6 (sk) 1998-11-12 1999-10-05 Spôsob zvýšenia výťažku prostriedku obsahujúceho interferón-alfa

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SK5003-2010A SK287564B6 (sk) 1998-11-12 1999-10-05 Spôsob zvýšenia výťažku prostriedku obsahujúceho interferón-alfa

Country Status (27)

Country Link
EP (2) EP1894944B1 (zh)
JP (3) JP4468585B2 (zh)
KR (1) KR100922454B1 (zh)
CN (2) CN100390197C (zh)
AR (1) AR023906A1 (zh)
AT (2) ATE409706T1 (zh)
AU (1) AU766309B2 (zh)
BR (1) BR9915257A (zh)
CA (1) CA2348739C (zh)
CY (2) CY1110444T1 (zh)
CZ (2) CZ303110B6 (zh)
DE (2) DE69939657D1 (zh)
DK (2) DK1894944T3 (zh)
ES (2) ES2315019T3 (zh)
HK (2) HK1112746A1 (zh)
HU (1) HU228265B1 (zh)
ID (1) ID28552A (zh)
IL (2) IL142546A0 (zh)
NO (2) NO329483B1 (zh)
NZ (1) NZ511074A (zh)
PL (2) PL200274B1 (zh)
PT (2) PT1129111E (zh)
SI (2) SI1894944T1 (zh)
SK (2) SK287564B6 (zh)
TW (1) TW577894B (zh)
WO (1) WO2000029440A1 (zh)
ZA (1) ZA200103010B (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4468585B2 (ja) * 1998-11-12 2010-05-26 シェーリング コーポレイション インターフェロンアイソフォームおよびその産物の変換の方法
JP2012513200A (ja) * 2008-12-23 2012-06-14 シェーリング コーポレイション 組換え製造インターフェロンの精製

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4530901A (en) 1980-01-08 1985-07-23 Biogen N.V. Recombinant DNA molecules and their use in producing human interferon-like polypeptides
IE54096B1 (en) 1980-01-08 1989-06-21 Biogen Nv Dn sequences, recombinant dna molecules and processes for producing human interferon - like polypeptides
US4315852A (en) 1980-11-26 1982-02-16 Schering Corporation Extraction of interferon from bacteria
US4364863A (en) * 1980-12-29 1982-12-21 Schering Corporation Extraction of interferon from bacteria
EP0082481B2 (en) 1981-12-23 1990-09-12 Schering Corporation Stabilised alpha-interferon formulations and their preparation
DE3515336C2 (de) * 1985-04-27 1994-01-20 Boehringer Ingelheim Int Verfahren zur Herstellung und Reinigung von â-Interferon
US4847079A (en) 1985-07-29 1989-07-11 Schering Corporation Biologically stable interferon compositions comprising thimerosal
US4732683A (en) 1986-12-02 1988-03-22 Biospectrum, Inc. Purification method for alpha interferon
US4765903A (en) 1987-10-06 1988-08-23 Interferon Sciences, Inc. Purification of monomeric interferon
US5272135A (en) 1991-03-01 1993-12-21 Chiron Ophthalmics, Inc. Method for the stabilization of methionine-containing polypeptides
AU648214B2 (en) * 1991-12-31 1994-04-14 Lucky Limited Recombinant gene coding for human alpha interferon and expression vector thereof, etc.
ES2161793T3 (es) * 1994-04-09 2001-12-16 Hoffmann La Roche Proceso para la produccion de alfa-interferona.
US5766582A (en) 1994-10-11 1998-06-16 Schering Corporation Stable, aqueous alfa interferon solution formulations
JP4468585B2 (ja) * 1998-11-12 2010-05-26 シェーリング コーポレイション インターフェロンアイソフォームおよびその産物の変換の方法

Also Published As

Publication number Publication date
HU228265B1 (en) 2013-02-28
JP2002530291A (ja) 2002-09-17
NO20012327L (no) 2001-05-11
DK1129111T3 (da) 2009-01-05
KR100922454B1 (ko) 2009-10-21
HK1112746A1 (en) 2008-09-12
ES2348104T3 (es) 2010-11-30
EP1894944B1 (en) 2010-08-04
ATE476445T1 (de) 2010-08-15
HUP0104113A3 (en) 2004-04-28
BR9915257A (pt) 2001-08-07
CY1110444T1 (el) 2015-04-29
CA2348739A1 (en) 2000-05-25
DE69942655D1 (de) 2010-09-16
NO20100775L (no) 2001-05-11
NO329483B1 (no) 2010-10-25
CN1326465A (zh) 2001-12-12
CN101255188A (zh) 2008-09-03
IL142546A (en) 2013-07-31
AU6387099A (en) 2000-06-05
EP1894944A1 (en) 2008-03-05
JP2010209117A (ja) 2010-09-24
AR023906A1 (es) 2002-09-04
AU766309B2 (en) 2003-10-16
CZ20011303A3 (cs) 2001-08-15
ID28552A (id) 2001-05-31
PL201341B1 (pl) 2009-04-30
PT1894944E (pt) 2010-10-28
WO2000029440A1 (en) 2000-05-25
NZ511074A (en) 2003-10-31
CN100390197C (zh) 2008-05-28
CZ302402B6 (cs) 2011-05-04
CY1110794T1 (el) 2015-06-10
SI1894944T1 (sl) 2010-11-30
JP4468585B2 (ja) 2010-05-26
EP1129111B1 (en) 2008-10-01
HUP0104113A2 (hu) 2002-03-28
SI1129111T1 (sl) 2009-06-30
SK6172001A3 (en) 2001-10-08
PL200274B1 (pl) 2008-12-31
PL348162A1 (en) 2002-05-06
ATE409706T1 (de) 2008-10-15
DE69939657D1 (de) 2008-11-13
PT1129111E (pt) 2008-12-22
ZA200103010B (en) 2002-07-11
TW577894B (en) 2004-03-01
EP1129111A1 (en) 2001-09-05
SK287564B6 (sk) 2011-02-04
KR20010080336A (ko) 2001-08-22
IL142546A0 (en) 2002-03-10
CA2348739C (en) 2010-05-11
CZ303110B6 (cs) 2012-04-04
HK1035544A1 (en) 2001-11-30
JP2006348056A (ja) 2006-12-28
NO331699B1 (no) 2012-02-27
ES2315019T3 (es) 2009-03-16
DK1894944T3 (da) 2010-10-18
NO20012327D0 (no) 2001-05-11

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Legal Events

Date Code Title Description
TC4A Change of owner's name

Owner name: MERCK SHARP & DOHME CORP., RAHWAY, NJ, US

Effective date: 20121108

MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20141005