SK285013B6 - Rekombinantná DNA, autonómne replikovateľná v bunkách koryneformných baktérií, koryneformná baktéria a spôsob výroby L-lyzínu - Google Patents
Rekombinantná DNA, autonómne replikovateľná v bunkách koryneformných baktérií, koryneformná baktéria a spôsob výroby L-lyzínu Download PDFInfo
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- SK285013B6 SK285013B6 SK1640-97A SK164097A SK285013B6 SK 285013 B6 SK285013 B6 SK 285013B6 SK 164097 A SK164097 A SK 164097A SK 285013 B6 SK285013 B6 SK 285013B6
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- dna
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
- C12N9/0016—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with NAD or NADP as acceptor (1.4.1)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1217—Phosphotransferases with a carboxyl group as acceptor (2.7.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP14061495 | 1995-06-07 | ||
| PCT/JP1996/001511 WO1996040934A1 (en) | 1995-06-07 | 1996-06-05 | Process for producing l-lysine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK164097A3 SK164097A3 (en) | 1998-07-08 |
| SK285013B6 true SK285013B6 (sk) | 2006-04-06 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK1640-97A SK285013B6 (sk) | 1995-06-07 | 1996-06-05 | Rekombinantná DNA, autonómne replikovateľná v bunkách koryneformných baktérií, koryneformná baktéria a spôsob výroby L-lyzínu |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US20020086370A1 (cs) |
| EP (1) | EP0841395B1 (cs) |
| JP (1) | JP3106501B2 (cs) |
| KR (1) | KR100268324B1 (cs) |
| CN (1) | CN1165619C (cs) |
| AU (1) | AU705550B2 (cs) |
| BR (1) | BR9606379A (cs) |
| CA (1) | CA2224058C (cs) |
| CZ (1) | CZ293268B6 (cs) |
| DK (1) | DK0841395T3 (cs) |
| ES (1) | ES2373863T3 (cs) |
| HU (1) | HU222503B1 (cs) |
| MX (1) | MX9709923A (cs) |
| RU (1) | RU2197528C2 (cs) |
| SK (1) | SK285013B6 (cs) |
| WO (1) | WO1996040934A1 (cs) |
| ZA (1) | ZA964665B (cs) |
Families Citing this family (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ293268B6 (cs) | 1995-06-07 | 2004-03-17 | Ajinomoto Co., Inc. | Rekombinantní DNA, bakterie a způsob výroby L-lyzinu |
| JP4035855B2 (ja) * | 1996-06-05 | 2008-01-23 | 味の素株式会社 | L−リジンの製造法 |
| SK285201B6 (sk) * | 1996-12-05 | 2006-08-03 | Ajinomoto Co., Inc. | Rekombinantná DNA, autonómne reprodukovaná v bunkách koryneformnej baktérie, koryneformná baktéria a spôsob výroby L-lyzínu, vektor pVK7 |
| JP4075087B2 (ja) * | 1996-12-05 | 2008-04-16 | 味の素株式会社 | L−リジンの製造法 |
| US6114145A (en) | 1997-12-05 | 2000-09-05 | Human Genome Sciences, Inc. | Synferon, a synthetic interferon |
| DE19931317A1 (de) * | 1999-07-07 | 2001-01-11 | Degussa | L-Lysin produzierende coryneforme Bakterien und Verfahren zur Herstellung von L-Lysin |
| JP3965821B2 (ja) * | 1999-03-09 | 2007-08-29 | 味の素株式会社 | L−リジンの製造法 |
| DE19912384A1 (de) * | 1999-03-19 | 2000-09-21 | Degussa | Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien |
| JP2003135066A (ja) * | 1999-03-19 | 2003-05-13 | Ajinomoto Co Inc | L−リジンの製造法 |
| AU3194300A (en) * | 1999-03-19 | 2000-10-09 | Ajinomoto Co., Inc. | Process for producing l-amino acid |
| JP2003144160A (ja) * | 1999-07-02 | 2003-05-20 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
| JP2003180348A (ja) * | 1999-07-02 | 2003-07-02 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
| JP2003169674A (ja) * | 1999-07-02 | 2003-06-17 | Ajinomoto Co Inc | L−リジンの製造法 |
| JP2003144161A (ja) * | 1999-07-02 | 2003-05-20 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
| JP2003180355A (ja) * | 1999-07-02 | 2003-07-02 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
| DE19931314A1 (de) * | 1999-07-07 | 2001-01-11 | Degussa | L-Lysin produzierende coryneforme Bakterien und Verfahren zur Herstellung von Lysin |
| JP2001046067A (ja) * | 1999-08-04 | 2001-02-20 | Ajinomoto Co Inc | 好熱性バチルス属細菌由来のl−リジン生合成系遺伝子 |
| PL341895A1 (en) * | 1999-08-12 | 2001-02-26 | Ajinomoto Kk | Plasmide autonomously replicable in corynebacter bacteria |
| US6927046B1 (en) * | 1999-12-30 | 2005-08-09 | Archer-Daniels-Midland Company | Increased lysine production by gene amplification using coryneform bacteria |
| MXPA03007089A (es) | 2001-02-08 | 2004-10-15 | Archer Daniels Midland Co | Construccion de polinucleotidos para produccion incrementada de lisina. |
| WO2003014330A2 (en) * | 2001-08-06 | 2003-02-20 | Degussa Ag | Coryneform bacteria which produce chemical compounds ii |
| DE60335774D1 (de) | 2002-11-26 | 2011-03-03 | Ajinomoto Kk | Methode für die Produktion von L-Glutamin und L-Glutamin-produzierendes Bakterium |
| JP4655539B2 (ja) * | 2004-08-06 | 2011-03-23 | 味の素株式会社 | アシラーゼを用いたβアミノ酸の製造方法 |
| PL2818556T3 (pl) | 2004-10-07 | 2023-07-17 | Ajinomoto Co., Inc. | Sposób wytwarzania zasadowej substancji |
| JP2009089603A (ja) * | 2006-02-02 | 2009-04-30 | Ajinomoto Co Inc | メタノール資化性細菌を用いたl−リジンの製造法 |
| EP2013353B1 (en) | 2006-03-30 | 2016-06-22 | Basf Se | Process for the production of cadaverine |
| JP2010041920A (ja) | 2006-12-19 | 2010-02-25 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
| JP2010088301A (ja) | 2007-02-01 | 2010-04-22 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
| JP2011067095A (ja) | 2008-01-10 | 2011-04-07 | Ajinomoto Co Inc | 発酵法による目的物質の製造法 |
| BRPI0906795A2 (pt) | 2008-01-23 | 2015-08-18 | Ajinomoto Kk | Método para produzir um l-aminoácido |
| CA2712427A1 (en) * | 2008-02-04 | 2009-08-13 | Basf Se | Method for the production of dipicolinate |
| WO2009109102A1 (en) | 2008-03-03 | 2009-09-11 | Global Bil-Chem Technology Group Company Limited | Recombinant microorganism and method for producing l-lysine |
| JP2012029565A (ja) | 2008-11-27 | 2012-02-16 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
| JP2010142200A (ja) | 2008-12-22 | 2010-07-01 | Ajinomoto Co Inc | L−リジンの製造法 |
| JPWO2011013707A1 (ja) | 2009-07-29 | 2013-01-10 | 味の素株式会社 | L−アミノ酸の製造法 |
| JP2012196144A (ja) | 2009-08-03 | 2012-10-18 | Ajinomoto Co Inc | ビブリオ属細菌を用いたl−リジンの製造法 |
| JP2012223091A (ja) | 2009-08-25 | 2012-11-15 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
| KR101226384B1 (ko) * | 2010-03-05 | 2013-01-25 | 씨제이제일제당 (주) | 개량된 프로모터 및 이를 이용한 l-라이신의 생산 방법 |
| EP2374873A1 (en) * | 2010-04-08 | 2011-10-12 | Technische Universität Hamburg-Harburg | Modified aspartate kinase from corynebacterium and its application for amino acid production |
| RU2011134436A (ru) | 2011-08-18 | 2013-10-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") | Способ получения l-аминокислоты с использованием бактерии семейства enterobacteriaceae, обладающей повышенной экспрессией генов каскада образования флагелл и клеточной подвижности |
| CN104334728B (zh) * | 2011-12-21 | 2018-09-25 | Cj第一制糖株式会社 | 利用具有产生l-赖氨酸能力的微生物产生l-赖氨酸的方法 |
| CN103667165B (zh) * | 2012-09-12 | 2017-05-31 | 中国科学院上海生命科学研究院 | 高产l‑赖氨酸的生产菌株及其应用 |
| JP2016192903A (ja) | 2013-09-17 | 2016-11-17 | 味の素株式会社 | 海藻由来バイオマスからのl−アミノ酸の製造方法 |
| BR112016007286B1 (pt) | 2013-10-02 | 2021-07-20 | Ajinomoto Co., Inc | Métodos de controle de amônia e para produção de uma substância alvo, e, aparelho para controle de amônia |
| KR101518860B1 (ko) * | 2013-10-11 | 2015-05-12 | 씨제이제일제당 (주) | L-아미노산의 생산 방법 |
| CN105821090B (zh) * | 2015-01-08 | 2019-12-13 | 中国科学院天津工业生物技术研究所 | 嗜热共生杆菌meso-二氨基庚二酸脱氢酶突变体应用 |
| EP3415622A1 (en) | 2017-06-14 | 2018-12-19 | Evonik Degussa GmbH | Method for production of fine chemicals using a corynebacterium secreting modified alpha-1,6-glucosidases |
| EP3456833A1 (en) | 2017-09-18 | 2019-03-20 | Evonik Degussa GmbH | Method for the fermentative production of l-amino acids |
| EP3467099A1 (en) | 2017-10-05 | 2019-04-10 | Evonik Degussa GmbH | Method for the fermentative production of l-amino acids |
| EP3498853A1 (en) | 2017-12-14 | 2019-06-19 | Evonik Degussa GmbH | Method for the fermentative production of l-lysine |
| EP3594355A1 (en) | 2018-07-12 | 2020-01-15 | Evonik Operations GmbH | Method for the fermentative production of l-lysine |
| EP3599282B1 (en) | 2018-07-24 | 2021-03-17 | Evonik Operations GmbH | Method for the fermentative production of l-lysine |
| RU2019128538A (ru) | 2018-09-26 | 2021-03-11 | Эвоник Оперейшенс ГмбХ | Способ ферментативного получения l-лизина |
| EP3660158A1 (en) | 2018-11-29 | 2020-06-03 | Evonik Operations GmbH | Method for the fermentative production of l-lysine |
| EP3670525A1 (en) | 2018-12-18 | 2020-06-24 | Evonik Operations GmbH | Method for the fermentative production of l-lysine using c. glutamicum strains with a mutated kup transporter |
| US10829746B2 (en) | 2019-01-23 | 2020-11-10 | Evonik Operations Gmbh | Method for the fermentative production of L-lysine |
| EP4405376B1 (en) | 2021-09-20 | 2025-08-27 | Evonik Operations GmbH | Method for the fermentative production of l-lysine using c. glutamicum strains expressing modified gluconate repressor proteins gntr1 and gntr2 |
| US20250313872A1 (en) | 2022-05-18 | 2025-10-09 | Evonik Operations Gmbh | Biotechnological production of bisucaberins, desferrioxamines and analogs thereof |
| WO2023222505A1 (en) | 2022-05-18 | 2023-11-23 | Evonik Operations Gmbh | Biotechnological production of monomers of bisucaberins, desferrioxamines and analogs thereof |
| CN119301244A (zh) | 2022-05-18 | 2025-01-10 | 赢创运营有限公司 | 去铁胺及其类似物的生物技术生产 |
| EP4613854A1 (en) | 2024-03-05 | 2025-09-10 | Evonik Operations GmbH | Method for the fermentative production of l-lysine using c. glutamicum strains expressing a heterologous nicotinamide nucleotide transhydrogenase pntab and having an increased activity of a myo-inositol permease |
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| JPH03147792A (ja) * | 1989-11-01 | 1991-06-24 | Mitsubishi Petrochem Co Ltd | 新規dna及び該dnaを含有するプラスミド |
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| JP4035855B2 (ja) * | 1996-06-05 | 2008-01-23 | 味の素株式会社 | L−リジンの製造法 |
| SK285201B6 (sk) * | 1996-12-05 | 2006-08-03 | Ajinomoto Co., Inc. | Rekombinantná DNA, autonómne reprodukovaná v bunkách koryneformnej baktérie, koryneformná baktéria a spôsob výroby L-lyzínu, vektor pVK7 |
| CN1170938C (zh) | 1998-09-25 | 2004-10-13 | 味之素株式会社 | 构建产生氨基酸的细菌的方法及通过发酵该经构建的产生氨基酸的细菌以制备氨基酸的方法 |
| US6893848B1 (en) * | 1999-04-19 | 2005-05-17 | Kyowa Hakko Kogyo Co., Ltd. | Desensitized aspartokinase |
| JP4254103B2 (ja) | 1999-07-02 | 2009-04-15 | 味の素株式会社 | シュークロースptsエンザイムiiをコードするdna |
| PL341895A1 (en) | 1999-08-12 | 2001-02-26 | Ajinomoto Kk | Plasmide autonomously replicable in corynebacter bacteria |
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1996
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- 1996-06-05 CA CA2224058A patent/CA2224058C/en not_active Expired - Lifetime
- 1996-06-05 SK SK1640-97A patent/SK285013B6/sk not_active IP Right Cessation
- 1996-06-05 US US08/952,976 patent/US20020086370A1/en not_active Abandoned
- 1996-06-05 ZA ZA964665A patent/ZA964665B/xx unknown
- 1996-06-05 WO PCT/JP1996/001511 patent/WO1996040934A1/ja not_active Ceased
- 1996-06-05 EP EP96916305A patent/EP0841395B1/en not_active Expired - Lifetime
- 1996-06-05 BR BR9606379A patent/BR9606379A/pt unknown
- 1996-06-05 MX MX9709923A patent/MX9709923A/es active IP Right Grant
- 1996-06-05 CN CNB961959525A patent/CN1165619C/zh not_active Expired - Lifetime
- 1996-06-05 DK DK96916305.4T patent/DK0841395T3/da active
- 1996-06-05 AU AU59107/96A patent/AU705550B2/en not_active Expired
- 1996-06-05 KR KR1019970709002A patent/KR100268324B1/ko not_active Expired - Lifetime
- 1996-06-05 JP JP09500307A patent/JP3106501B2/ja not_active Expired - Lifetime
- 1996-06-05 RU RU98100099/13A patent/RU2197528C2/ru active
- 1996-06-05 ES ES96916305T patent/ES2373863T3/es not_active Expired - Lifetime
- 1996-06-05 HU HU9802666A patent/HU222503B1/hu active IP Right Grant
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Also Published As
| Publication number | Publication date |
|---|---|
| US20110065153A1 (en) | 2011-03-17 |
| US20020086370A1 (en) | 2002-07-04 |
| CA2224058A1 (en) | 1996-12-19 |
| EP0841395A1 (en) | 1998-05-13 |
| EP0841395A4 (en) | 2005-07-27 |
| US7846698B2 (en) | 2010-12-07 |
| EP0841395B1 (en) | 2011-11-02 |
| US8183017B2 (en) | 2012-05-22 |
| DK0841395T3 (da) | 2012-01-09 |
| ZA964665B (en) | 1997-01-07 |
| BR9606379A (pt) | 1997-08-12 |
| MX9709923A (es) | 1998-03-31 |
| HUP9802666A2 (hu) | 1999-02-01 |
| RU2197528C2 (ru) | 2003-01-27 |
| CZ390397A3 (cs) | 1998-06-17 |
| CN1165619C (zh) | 2004-09-08 |
| HUP9802666A3 (en) | 2001-08-28 |
| CN1192242A (zh) | 1998-09-02 |
| CZ293268B6 (cs) | 2004-03-17 |
| KR100268324B1 (ko) | 2000-10-16 |
| SK164097A3 (en) | 1998-07-08 |
| JP3106501B2 (ja) | 2000-11-06 |
| HU222503B1 (hu) | 2003-07-28 |
| US20030054506A1 (en) | 2003-03-20 |
| AU705550B2 (en) | 1999-05-27 |
| ES2373863T3 (es) | 2012-02-09 |
| KR19990022521A (ko) | 1999-03-25 |
| WO1996040934A1 (en) | 1996-12-19 |
| CA2224058C (en) | 2011-09-13 |
| AU5910796A (en) | 1996-12-30 |
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| MK4A | Expiry of patent |
Expiry date: 20160605 |