SK284493B6 - Sferoidy, spôsob ich prípravy a farmaceutické prostriedky s ich obsahom - Google Patents

Sferoidy, spôsob ich prípravy a farmaceutické prostriedky s ich obsahom Download PDF

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Publication number
SK284493B6
SK284493B6 SK756-2000A SK7562000A SK284493B6 SK 284493 B6 SK284493 B6 SK 284493B6 SK 7562000 A SK7562000 A SK 7562000A SK 284493 B6 SK284493 B6 SK 284493B6
Authority
SK
Slovakia
Prior art keywords
spheroids
core
thermoplastic
substance
tablets
Prior art date
Application number
SK756-2000A
Other languages
English (en)
Slovak (sk)
Other versions
SK7562000A3 (en
Inventor
Patrice Debregeas
G�Rard Leduc
Pascal Oury
Pascal Suplie
Original Assignee
Laboratoires Des Produits Ethiques Ethypharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Des Produits Ethiques Ethypharm filed Critical Laboratoires Des Produits Ethiques Ethypharm
Publication of SK7562000A3 publication Critical patent/SK7562000A3/sk
Publication of SK284493B6 publication Critical patent/SK284493B6/sk

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SK756-2000A 1997-11-21 1998-11-19 Sferoidy, spôsob ich prípravy a farmaceutické prostriedky s ich obsahom SK284493B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9714631A FR2771291B1 (fr) 1997-11-21 1997-11-21 Spheroides, procede de preparation et compositions pharmaceutiques
PCT/IB1998/001911 WO1999026608A1 (fr) 1997-11-21 1998-11-19 Spheroides, procede de preparation et compositions pharmaceutiques

Publications (2)

Publication Number Publication Date
SK7562000A3 SK7562000A3 (en) 2001-06-11
SK284493B6 true SK284493B6 (sk) 2005-05-05

Family

ID=9513635

Family Applications (1)

Application Number Title Priority Date Filing Date
SK756-2000A SK284493B6 (sk) 1997-11-21 1998-11-19 Sferoidy, spôsob ich prípravy a farmaceutické prostriedky s ich obsahom

Country Status (29)

Country Link
US (1) US6077544A (de)
EP (1) EP1032374B1 (de)
JP (1) JP2001523706A (de)
KR (1) KR100502938B1 (de)
CN (1) CN1223341C (de)
AT (1) ATE246496T1 (de)
AU (1) AU744580B2 (de)
BG (1) BG65117B1 (de)
BR (1) BR9814672A (de)
CA (1) CA2310147C (de)
CZ (1) CZ299110B6 (de)
DE (1) DE69817010T2 (de)
DK (1) DK1032374T3 (de)
EA (1) EA003324B1 (de)
ES (1) ES2203989T3 (de)
FR (1) FR2771291B1 (de)
HR (1) HRP20000323B1 (de)
HU (1) HU230053B1 (de)
IL (2) IL136215A0 (de)
MX (1) MXPA00004959A (de)
NO (1) NO329728B1 (de)
NZ (1) NZ504662A (de)
PL (1) PL193878B1 (de)
PT (1) PT1032374E (de)
SK (1) SK284493B6 (de)
TR (1) TR200002130T2 (de)
WO (1) WO1999026608A1 (de)
YU (1) YU31000A (de)
ZA (1) ZA9810631B (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2790668B1 (fr) * 1999-03-12 2002-07-26 D B F Granules contenant une substance vegetale et leur procede de preparation
BR0009557A (pt) 1999-04-06 2002-05-28 Ethypharm Lab Prod Ethiques Suspensão farmacêutica para beber de ibuprofeno
FR2794646B1 (fr) 1999-06-09 2001-09-21 Ethypharm Lab Prod Ethiques Microgranules de sulfate de morphine, procede de preparation et composition les contenant
DK1414956T3 (da) 2001-06-22 2008-03-03 Genencor Int Höjt påvirkningsresistente granula
AR034813A1 (es) 2001-07-20 2004-03-17 Novartis Ag Composiciones farmaceuticas y uso de las mismas
FR2830447B1 (fr) * 2001-10-09 2004-04-16 Flamel Tech Sa Forme galenique orale microparticulaire pour la liberation retardee et controlee de principes actifs pharmaceutiques
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
FR2837100B1 (fr) * 2002-03-18 2004-07-23 Flamel Tech Sa Comprimes a bases de microcapsules a liberation modifiee
CA2480826C (fr) 2002-04-09 2012-02-07 Flamel Technologies Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee de principe(s) actif(s)
IL164221A0 (en) * 2002-04-09 2005-12-18 Flamel Tech Sa Oral pharmaceutical formulation in the form of aqueous suspension of microcapsules for modified release of amoxicillim
FR2838647B1 (fr) * 2002-04-23 2006-02-17 Particules enrobees a liberation prolongee, leur procede de preparation et comprimes les contenant
US20040013737A1 (en) * 2002-07-19 2004-01-22 Philippe Becourt Taste masked oral composition of telithromycin
FR2845289B1 (fr) 2002-10-04 2004-12-03 Ethypharm Sa Spheroides, procede de preparation et compositions pharmaceutiques.
US9107804B2 (en) * 2002-12-10 2015-08-18 Nortec Development Associates, Inc. Method of preparing biologically active formulations
NZ523946A (en) * 2003-01-31 2004-06-25 Carl Ernest Alexander Portable hygiene compositions comprising a semi-solid gel and active ingredients in bead form for use in personal oral, dental or skin care
ES2221804B1 (es) * 2003-06-18 2006-04-01 Lipofoods, S.L. Microcapsulas para la administracion de ingredientes activos.
BRPI0415242B8 (pt) * 2003-10-10 2021-05-25 Ethypharm Sa microgrânulos de liberação gradual contendo extrato de gingko biloba e o processo para fabricar estes
FR2861990B1 (fr) 2003-11-10 2006-02-10 Nouveaux Produits Pharma Comprimes faiblement doses a reseau de polymeres
DE602005003343T2 (de) * 2004-04-12 2008-09-11 Pfizer Products Inc., Groton Arzneiimittel mit verdecktem geschmack in aufbrechenden multipartikeln
WO2005123042A1 (en) * 2004-06-10 2005-12-29 Glatt Air Techniques, Inc. Controlled release pharmaceutical formulation
FR2883179B1 (fr) * 2005-03-18 2009-04-17 Ethypharm Sa Comprime enrobe
US20100233257A1 (en) * 2006-06-09 2010-09-16 Ethypharm Low dose sublingual tablets of opioid analgesics and preparation process
US20070286900A1 (en) * 2006-06-09 2007-12-13 Catherine Herry Low dose tablets of opioid analgesics and preparation process
US11116728B2 (en) 2006-11-30 2021-09-14 Bend Research, Inc. Multiparticulates of spray-coated drug and polymer on a meltable core
EP2091519B1 (de) * 2006-11-30 2015-06-24 Bend Research, Inc Multiteilchen eines spray-überzogenen arzneimittels und polymer auf einem schmelzbaren kern
EP2468263A1 (de) * 2010-12-23 2012-06-27 Laboratorios Del. Dr. Esteve, S.A. Komprimierte feste Darreichungsformen
US11117180B2 (en) 2018-05-11 2021-09-14 Stolle Machinery Company, Llc Quick change tooling assembly
CN112118921B (zh) 2018-05-11 2023-04-18 斯多里机械有限责任公司 旋转歧管
EP3790822A4 (de) 2018-05-11 2022-01-26 Stolle Machinery Company, LLC Prozessschaftwerkzeuganordnung
JP7331017B2 (ja) 2018-05-11 2023-08-22 ストール マシーナリ カンパニー,エルエルシー 駆動アセンブリ
WO2019217686A1 (en) 2018-05-11 2019-11-14 Stolle Machinery Company, Llc Infeed assembly full inspection assembly
WO2019217607A2 (en) 2018-05-11 2019-11-14 Stolle Machinery Company, Llc Infeed assembly quick change features
WO2019217614A1 (en) 2018-05-11 2019-11-14 Stolle Machinery Company, Llc Quick change transfer assembly
US11420242B2 (en) 2019-08-16 2022-08-23 Stolle Machinery Company, Llc Reformer assembly

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4684516A (en) * 1983-08-01 1987-08-04 Alra Laboratories, Inc. Sustained release tablets and method of making same
NZ230763A (en) * 1988-09-27 1991-10-25 Takeda Chemical Industries Ltd Production of granules having a core by spraying the cores with a dispersion of hydroxypropylcellulose, optionally incorporating an active ingredient
EP0418596A3 (en) * 1989-09-21 1991-10-23 American Cyanamid Company Controlled release pharmaceutical compositions from spherical granules in tabletted oral dosage unit form
JP2572673B2 (ja) * 1990-07-25 1997-01-16 エスエス製薬株式会社 徐放性錠剤
FR2679451B1 (fr) * 1991-07-22 1994-09-09 Prographarm Laboratoires Comprime multiparticulaire a delitement rapide.
GB9117361D0 (en) * 1991-08-12 1991-09-25 Euro Celtique Sa Oral dosage form
FR2692146B1 (fr) * 1992-06-16 1995-06-02 Ethypharm Sa Compositions stables de microgranules d'omeprazole gastro-protégés et leur procédé d'obtention.
CN1071570C (zh) * 1993-06-14 2001-09-26 詹森药业有限公司 阿司咪唑和假麻黄碱的缓释薄膜包衣片
SE9402422D0 (sv) * 1994-07-08 1994-07-08 Astra Ab New beads for controlled release and a pharmaceutical preparation containing the same
SE9600070D0 (sv) * 1996-01-08 1996-01-08 Astra Ab New oral pharmaceutical dosage forms
FR2771292B1 (fr) * 1997-11-21 2000-02-18 Ethypharm Lab Prod Ethiques Spheroides contenant de la tiagabine, procede de preparation et compositions pharmaceutiques

Also Published As

Publication number Publication date
IL136215A0 (en) 2001-05-20
EP1032374B1 (de) 2003-08-06
CA2310147C (fr) 2010-05-25
AU744580B2 (en) 2002-02-28
AU1170499A (en) 1999-06-15
EA003324B1 (ru) 2003-04-24
CZ299110B6 (cs) 2008-04-23
TR200002130T2 (tr) 2000-12-21
FR2771291A1 (fr) 1999-05-28
HRP20000323A2 (en) 2001-06-30
FR2771291B1 (fr) 2000-02-25
HUP0100562A2 (hu) 2002-05-29
HUP0100562A3 (en) 2002-08-28
JP2001523706A (ja) 2001-11-27
EP1032374A1 (de) 2000-09-06
US6077544A (en) 2000-06-20
HU230053B1 (hu) 2015-06-29
ZA9810631B (en) 1999-05-24
KR20010032329A (ko) 2001-04-16
PL340659A1 (en) 2001-02-12
BG65117B1 (bg) 2007-03-30
KR100502938B1 (ko) 2005-07-25
NZ504662A (en) 2002-09-27
BR9814672A (pt) 2000-10-03
CZ20001849A3 (cs) 2000-10-11
IL136215A (en) 2006-12-31
NO20002605D0 (no) 2000-05-19
PL193878B1 (pl) 2007-03-30
ATE246496T1 (de) 2003-08-15
WO1999026608A1 (fr) 1999-06-03
NO329728B1 (no) 2010-12-06
MXPA00004959A (es) 2002-10-17
NO20002605L (no) 2000-07-05
PT1032374E (pt) 2003-12-31
ES2203989T3 (es) 2004-04-16
SK7562000A3 (en) 2001-06-11
CN1282239A (zh) 2001-01-31
BG104511A (en) 2001-04-30
EA200000548A1 (ru) 2000-12-25
DE69817010D1 (de) 2003-09-11
DE69817010T2 (de) 2004-05-27
HRP20000323B1 (en) 2006-07-31
CA2310147A1 (fr) 1999-06-03
DK1032374T3 (da) 2003-11-24
CN1223341C (zh) 2005-10-19
YU31000A (sh) 2002-11-15

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