SK283996B6 - Spôsob výroby R- alebo S-norbenzomorfánov - Google Patents

Spôsob výroby R- alebo S-norbenzomorfánov Download PDF

Info

Publication number
SK283996B6
SK283996B6 SK1731-2000A SK17312000A SK283996B6 SK 283996 B6 SK283996 B6 SK 283996B6 SK 17312000 A SK17312000 A SK 17312000A SK 283996 B6 SK283996 B6 SK 283996B6
Authority
SK
Slovakia
Prior art keywords
process according
acid
reaction
aluminum
piperidine derivative
Prior art date
Application number
SK1731-2000A
Other languages
English (en)
Slovak (sk)
Other versions
SK17312000A3 (sk
Inventor
Matthias Grauert
Hanfried Baltes
J�rgen SCHNAUBELT
Original Assignee
Boehringer Ingelheim Pharma Gmbh & Co. Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma Gmbh & Co. Kg filed Critical Boehringer Ingelheim Pharma Gmbh & Co. Kg
Publication of SK17312000A3 publication Critical patent/SK17312000A3/sk
Publication of SK283996B6 publication Critical patent/SK283996B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
SK1731-2000A 1998-05-20 1999-05-07 Spôsob výroby R- alebo S-norbenzomorfánov SK283996B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19822822A DE19822822A1 (de) 1998-05-20 1998-05-20 Verbessertes Verfahren zur Herstellung von pharmazeutisch wertvollen Norbenzomorphanderivaten
PCT/EP1999/003142 WO1999059976A1 (de) 1998-05-20 1999-05-07 Verbessertes verfahren zur herstellung von pharmazeutisch wertvollen norbenzomorphanderivaten

Publications (2)

Publication Number Publication Date
SK17312000A3 SK17312000A3 (sk) 2001-06-11
SK283996B6 true SK283996B6 (sk) 2004-07-07

Family

ID=7868527

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1731-2000A SK283996B6 (sk) 1998-05-20 1999-05-07 Spôsob výroby R- alebo S-norbenzomorfánov

Country Status (38)

Country Link
US (1) US6124459A (ru)
EP (1) EP1080076B1 (ru)
JP (1) JP4526185B2 (ru)
KR (1) KR20010043703A (ru)
CN (1) CN1113058C (ru)
AR (1) AR016040A1 (ru)
AT (1) ATE254605T1 (ru)
AU (1) AU753563B2 (ru)
BG (1) BG104964A (ru)
BR (1) BR9910603A (ru)
CA (1) CA2330669C (ru)
CO (1) CO5060460A1 (ru)
DE (2) DE19822822A1 (ru)
DK (1) DK1080076T3 (ru)
EA (1) EA003059B1 (ru)
EE (1) EE04305B1 (ru)
EG (1) EG21526A (ru)
ES (1) ES2211093T3 (ru)
HK (1) HK1035728A1 (ru)
HR (1) HRP20000793A2 (ru)
HU (1) HUP0102034A3 (ru)
ID (1) ID27014A (ru)
IL (1) IL138998A0 (ru)
MY (1) MY120806A (ru)
NO (1) NO317302B1 (ru)
NZ (1) NZ508845A (ru)
PE (1) PE20000558A1 (ru)
PL (1) PL343935A1 (ru)
PT (1) PT1080076E (ru)
SI (1) SI1080076T1 (ru)
SK (1) SK283996B6 (ru)
TR (1) TR200003360T2 (ru)
TW (1) TW455582B (ru)
UA (1) UA59448C2 (ru)
UY (1) UY25515A1 (ru)
WO (1) WO1999059976A1 (ru)
YU (1) YU71400A (ru)
ZA (1) ZA200005740B (ru)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7405149B1 (en) * 1998-12-21 2008-07-29 Megica Corporation Post passivation method for semiconductor chip or wafer
WO2016044546A1 (en) * 2014-09-17 2016-03-24 Purdue Pharma L.P. Benzomorphan analogs and the use thereof
CN107089948B (zh) * 2017-04-28 2020-07-17 云南大学 吗吩衍生物及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE34235B1 (en) * 1969-06-04 1975-03-19 Acf Chemiefarma Nv 6,7-benzomorphans and their preparation
US3932422A (en) * 1974-05-20 1976-01-13 Sterling Drug Inc. 8-Methylene-3-azabicyclo[3.3.1]non-6-en-4-ones
US4255579A (en) * 1974-05-20 1981-03-10 Sterling Drug Inc. 11-Substituted hexahydro-2,6-methano-3-benzazocines
DE19528472A1 (de) * 1995-08-03 1997-02-06 Boehringer Ingelheim Kg Neues Verfahren zur Herstellung von Norbenzomorphan einer Zwischenstufe bei Herstellung von pharmazeutisch wertvollen Benzomorphanderivaten, insbesondere von (-)-(1R,5S,S"R)-3'-Hydroxy-2-(2-methoxypropyl-)-5,9,9-trimethyl-6,7 benzomorphan

Also Published As

Publication number Publication date
DK1080076T3 (da) 2004-03-22
PT1080076E (pt) 2004-04-30
AU753563B2 (en) 2002-10-24
ES2211093T3 (es) 2004-07-01
SI1080076T1 (en) 2004-04-30
NO20005818L (no) 2000-11-17
DE59907804D1 (de) 2003-12-24
HUP0102034A3 (en) 2002-02-28
BG104964A (en) 2001-07-31
UY25515A1 (es) 1999-12-13
EE04305B1 (et) 2004-06-15
KR20010043703A (ko) 2001-05-25
BR9910603A (pt) 2001-01-16
TW455582B (en) 2001-09-21
JP4526185B2 (ja) 2010-08-18
EP1080076B1 (de) 2003-11-19
AU4139999A (en) 1999-12-06
NZ508845A (en) 2002-11-26
YU71400A (sh) 2003-04-30
DE19822822A1 (de) 1999-11-25
HUP0102034A2 (hu) 2001-12-28
CA2330669A1 (en) 1999-11-25
HRP20000793A2 (en) 2001-10-31
NO317302B1 (no) 2004-10-04
PL343935A1 (en) 2001-09-10
ID27014A (id) 2001-02-22
ZA200005740B (en) 2001-10-17
CA2330669C (en) 2008-07-15
CN1301256A (zh) 2001-06-27
US6124459A (en) 2000-09-26
TR200003360T2 (tr) 2001-06-21
EA003059B1 (ru) 2002-12-26
EP1080076A1 (de) 2001-03-07
NO20005818D0 (no) 2000-11-17
JP2002515491A (ja) 2002-05-28
ATE254605T1 (de) 2003-12-15
SK17312000A3 (sk) 2001-06-11
CN1113058C (zh) 2003-07-02
WO1999059976A1 (de) 1999-11-25
UA59448C2 (ru) 2003-09-15
IL138998A0 (en) 2001-11-25
AR016040A1 (es) 2001-05-30
EA200001212A1 (ru) 2001-04-23
PE20000558A1 (es) 2000-06-28
CO5060460A1 (es) 2001-07-30
EE200000674A (et) 2002-04-15
MY120806A (en) 2005-11-30
HK1035728A1 (en) 2001-12-07
EG21526A (en) 2001-11-28

Similar Documents

Publication Publication Date Title
WO2016079751A2 (en) A process for preparation of vortioxetine and polymorphs thereof
US20190112273A1 (en) An improved process for the preparation of butorphanol tartrate
SK283996B6 (sk) Spôsob výroby R- alebo S-norbenzomorfánov
BR112019017309A2 (pt) Protodescarboxilação catalisada por metal de transição de derivados de ácido alfa-halo-acrílico
Yamaguchi et al. The synthesis of benzofuroquinolines. IX. A benzofuroisoquinolinone and a benzofuroisocoumarin
SU513624A3 (ru) Способ получени производных 2-пиперазинил-тиазола
Sommer et al. Application of (2-cyanoaryl) arylacetonitriles in cyclization and annulation reactions. Preparation of 3-arylindans, 4-aryl-3, 4-dihydronaphthalenes, 4-arylisoquinolines, 1-aminonaphthalenes, and heterocyclic analogues
EP1259509B1 (en) Process for the preparation of 6-methyl-2-(4-methyl-phenyl)-imidazo 1,2-a]pyridine-3-(n,n-dimethyl-acetamide) and intermediates
CZ20004323A3 (cs) Způsob výroby R- a S- norbenzomorfanů
EP2070899A1 (en) Deprotection of N-BOC compounds
EP1366034B1 (en) Preparation of phthalanes
EA027080B1 (ru) Способ синтеза (2e)-3-(3,4-диметоксифенил)проп-2-еннитрила, применение в синтезе ивабрадина и его фармацевтически приемлемых кислотно-аддитивных солей
MXPA00010964A (en) Improved method for preparing pharmaceutically valuable norbenzomorphane derivatives
Kakehi et al. Preparation of new nitrogen-bridged heterocycles. 21. A facile synthesis of 2-indolizinethiols using new protecting groups.
US5578728A (en) Process for the preparation of a benzo(a)quinolizione derivative
US3125580A (en) x d diphenyl -
KR930010500B1 (ko) 코타르닌의 제조방법
US6573384B1 (en) Process for production of indole derivatives and intermediates therefor
EP2234975B1 (en) Process for producing pipecolic-2-acid-2 ',6'-xylidide useful as an intermediate for the preparation of local anesthetics
EP0131921A2 (en) Ortho-(mono-substituted amino)phenylimines and production thereof
KR900006325B1 (ko) 벤즈아제핀 유도체의 제조방법
Li et al. Synthesis of functionalized tetrahydro-β-carboline derivatives by modified pictet-spengler reaction
Hengchang et al. A Facile Synthesis of Unsymmetrical Sulfides Under Phase Transfer Conditions
RU2395488C1 (ru) Способ получения фармацевтически приемлемых солей дес-глауцина
CA2360456A1 (en) Novel process of preparing a benzothiazolone compound