SK283970B6 - Tricyklické zlúčeniny, spôsob výroby a farmaceutický prípravok ich obsahujúci - Google Patents

Tricyklické zlúčeniny, spôsob výroby a farmaceutický prípravok ich obsahujúci Download PDF

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Publication number
SK283970B6
SK283970B6 SK1150-98A SK115098A SK283970B6 SK 283970 B6 SK283970 B6 SK 283970B6 SK 115098 A SK115098 A SK 115098A SK 283970 B6 SK283970 B6 SK 283970B6
Authority
SK
Slovakia
Prior art keywords
group
alkyl
carbon atoms
compound
aryl
Prior art date
Application number
SK1150-98A
Other languages
English (en)
Slovak (sk)
Other versions
SK115098A3 (en
Inventor
Shigenori Ohkawa
Osamu Uchikawa
Kohji Fukatsu
Masaomi Miyamoto
Original Assignee
Takeda Chemical Industries, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27286462&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SK283970(B6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Chemical Industries, Ltd. filed Critical Takeda Chemical Industries, Ltd.
Publication of SK115098A3 publication Critical patent/SK115098A3/sk
Publication of SK283970B6 publication Critical patent/SK283970B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/70—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with ring systems containing two or more relevant rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Indole Compounds (AREA)
SK1150-98A 1996-03-08 1997-03-05 Tricyklické zlúčeniny, spôsob výroby a farmaceutický prípravok ich obsahujúci SK283970B6 (sk)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP5149196 1996-03-08
JP18366796 1996-07-12
JP2918597 1997-02-13
PCT/JP1997/000677 WO1997032871A1 (fr) 1996-03-08 1997-03-05 Composes tricycliques, leur production et leur utilisation

Publications (2)

Publication Number Publication Date
SK115098A3 SK115098A3 (en) 1999-03-12
SK283970B6 true SK283970B6 (sk) 2004-06-08

Family

ID=27286462

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1150-98A SK283970B6 (sk) 1996-03-08 1997-03-05 Tricyklické zlúčeniny, spôsob výroby a farmaceutický prípravok ich obsahujúci

Country Status (20)

Country Link
US (1) US6218429B1 (fr)
EP (2) EP1550655A1 (fr)
JP (1) JP4358917B2 (fr)
KR (1) KR100494214B1 (fr)
CN (3) CN100441574C (fr)
AT (1) ATE219071T1 (fr)
CA (1) CA2241666C (fr)
CZ (1) CZ291626B6 (fr)
DE (1) DE69713294T3 (fr)
DK (1) DK0885210T5 (fr)
ES (1) ES2175350T5 (fr)
HK (1) HK1087112A1 (fr)
HU (1) HU224220B1 (fr)
NO (1) NO322205B1 (fr)
NZ (1) NZ330656A (fr)
PL (1) PL188093B1 (fr)
PT (1) PT885210E (fr)
SK (1) SK283970B6 (fr)
TW (1) TW562803B (fr)
WO (1) WO1997032871A1 (fr)

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WO2002040053A1 (fr) * 2000-11-17 2002-05-23 Takeda Chemical Industries, Ltd. Preparation pharmaceutique contenant du talc/ du sulfate de baryum
CA2428817C (fr) * 2000-11-17 2010-06-01 Takeda Chemical Industries, Ltd. Preparation pharmaceutique contenant de la copolyvidone
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EA200971003A1 (ru) 2007-04-26 2010-04-30 Такеда Фармасьютикал Компани Лимитед Бициклическое соединение и его фармацевтическое применение
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CN102391220A (zh) * 2011-10-10 2012-03-28 四川大学 三环乙醇类化合物及其制备方法和用途
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EP2884275A4 (fr) 2012-07-10 2016-04-13 Astellas Pharma Inc Composition pharmaceutique destinée à traiter ou à prévenir l'incontinence urinaire de stress ou l'incontinence mixte, et procédé de criblage pour identifier les composés à inclure dans ladite composition pharmaceutique
AR091699A1 (es) 2012-07-10 2015-02-25 Astellas Pharma Inc Derivado de indol carboxamida
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CN102924410A (zh) * 2012-10-29 2013-02-13 华润赛科药业有限责任公司 一种雷美替胺的制备方法及其中间体
US8822719B1 (en) 2013-03-05 2014-09-02 Ecolab Usa Inc. Peroxycarboxylic acid compositions suitable for inline optical or conductivity monitoring
US20140256811A1 (en) 2013-03-05 2014-09-11 Ecolab Usa Inc. Efficient stabilizer in controlling self accelerated decomposition temperature of peroxycarboxylic acid compositions with mineral acids
US10165774B2 (en) 2013-03-05 2019-01-01 Ecolab Usa Inc. Defoamer useful in a peracid composition with anionic surfactants
CA2934825A1 (fr) 2014-01-14 2015-07-23 Shunichiro Matsumoto Compose indole
AU2017205722B2 (en) 2016-01-08 2022-02-17 Takeda Pharmaceutical Company Limited Prophylactic or therapeutic agent for autism spectrum disorder
WO2017119456A1 (fr) 2016-01-08 2017-07-13 武田薬品工業株式会社 Agent de traitement prophylactique ou thérapeutique du délire
WO2021026410A1 (fr) 2019-08-07 2021-02-11 Ecolab Usa Inc. Chélateurs à support solide et polymère pour la stabilisation de compositions contenant un peracide
CN110776485B (zh) * 2019-11-22 2022-09-30 山东邹平大展新材料有限公司 一种雷美替胺杂质的制备方法
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Also Published As

Publication number Publication date
NO322205B1 (no) 2006-08-28
CA2241666C (fr) 2007-11-06
DK0885210T3 (da) 2002-10-07
JPH11152281A (ja) 1999-06-08
CZ277598A3 (cs) 1998-12-16
PT885210E (pt) 2002-09-30
CN100443480C (zh) 2008-12-17
CN1212691A (zh) 1999-03-31
DE69713294T2 (de) 2003-02-13
CN100441574C (zh) 2008-12-10
NZ330656A (en) 1999-06-29
HU224220B1 (hu) 2005-06-28
DE69713294D1 (de) 2002-07-18
NO983970D0 (no) 1998-08-28
KR100494214B1 (ko) 2005-11-25
US6218429B1 (en) 2001-04-17
WO1997032871A1 (fr) 1997-09-12
CN1727339A (zh) 2006-02-01
AU706610B2 (en) 1999-06-17
DK0885210T4 (da) 2008-09-08
HK1087112A1 (en) 2006-10-06
HUP9900616A2 (hu) 1999-06-28
EP1550655A1 (fr) 2005-07-06
EP0885210A1 (fr) 1998-12-23
EP0885210B1 (fr) 2002-06-12
TW562803B (en) 2003-11-21
AU2231897A (en) 1997-09-22
KR19990087628A (ko) 1999-12-27
EP0885210B2 (fr) 2008-06-18
CN1900067A (zh) 2007-01-24
DE69713294T3 (de) 2009-01-15
NO983970L (no) 1998-08-28
ATE219071T1 (de) 2002-06-15
ES2175350T5 (es) 2008-12-16
SK115098A3 (en) 1999-03-12
JP4358917B2 (ja) 2009-11-04
CA2241666A1 (fr) 1997-09-12
CZ291626B6 (cs) 2003-04-16
HUP9900616A3 (en) 2002-11-28
DK0885210T5 (da) 2008-10-13
ES2175350T3 (es) 2002-11-16
PL188093B1 (pl) 2004-12-31
PL328726A1 (en) 1999-02-15

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