SK282186B6 - Použitie purifikovanej zlúčeniny na výrobu liečiva na inhibíciu aktivity steroidnej sulfatázy - Google Patents

Použitie purifikovanej zlúčeniny na výrobu liečiva na inhibíciu aktivity steroidnej sulfatázy Download PDF

Info

Publication number
SK282186B6
SK282186B6 SK246-94A SK24694A SK282186B6 SK 282186 B6 SK282186 B6 SK 282186B6 SK 24694 A SK24694 A SK 24694A SK 282186 B6 SK282186 B6 SK 282186B6
Authority
SK
Slovakia
Prior art keywords
estrone
activity
compound
group
sulfamate
Prior art date
Application number
SK246-94A
Other languages
English (en)
Slovak (sk)
Other versions
SK24694A3 (en
Inventor
Michael John Reed
Barry Victor Lloyd Potter
Original Assignee
Sterix Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterix Limited filed Critical Sterix Limited
Publication of SK24694A3 publication Critical patent/SK24694A3/sk
Publication of SK282186B6 publication Critical patent/SK282186B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/36—Antigestagens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Surgical Instruments (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SK246-94A 1991-08-29 1992-08-28 Použitie purifikovanej zlúčeniny na výrobu liečiva na inhibíciu aktivity steroidnej sulfatázy SK282186B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919118478A GB9118478D0 (en) 1991-08-29 1991-08-29 Steroid sulphatase inhibitors
PCT/GB1992/001587 WO1993005064A1 (en) 1991-08-29 1992-08-28 Steroid sulphatase inhibitors

Publications (2)

Publication Number Publication Date
SK24694A3 SK24694A3 (en) 1994-11-09
SK282186B6 true SK282186B6 (sk) 2001-12-03

Family

ID=10700604

Family Applications (4)

Application Number Title Priority Date Filing Date
SK246-94A SK282186B6 (sk) 1991-08-29 1992-08-28 Použitie purifikovanej zlúčeniny na výrobu liečiva na inhibíciu aktivity steroidnej sulfatázy
SK1254-2000A SK282189B6 (sk) 1991-08-29 1992-08-28 Farmaceutický prostriedok s obsahom purifikovanej zlúčeniny
SK1253-2000A SK282188B6 (sk) 1991-08-29 1992-08-28 Purifikovaná zlúčenina
SK1252-2000A SK282187B6 (sk) 1991-08-29 1992-08-28 Použitie zlúčeniny s cyklickým systémom

Family Applications After (3)

Application Number Title Priority Date Filing Date
SK1254-2000A SK282189B6 (sk) 1991-08-29 1992-08-28 Farmaceutický prostriedok s obsahom purifikovanej zlúčeniny
SK1253-2000A SK282188B6 (sk) 1991-08-29 1992-08-28 Purifikovaná zlúčenina
SK1252-2000A SK282187B6 (sk) 1991-08-29 1992-08-28 Použitie zlúčeniny s cyklickým systémom

Country Status (26)

Country Link
US (3) US5616574A (uk)
EP (6) EP0982032B1 (uk)
JP (6) JP3219408B2 (uk)
KR (4) KR100258396B1 (uk)
AT (5) ATE237333T1 (uk)
AU (2) AU689043B2 (uk)
BR (1) BR9206434A (uk)
CA (4) CA2305767A1 (uk)
CY (4) CY2253B1 (uk)
CZ (1) CZ295939B6 (uk)
DE (5) DE69233053T2 (uk)
DK (4) DK0921130T3 (uk)
ES (4) ES2148178T3 (uk)
FI (5) FI940903A (uk)
GB (1) GB9118478D0 (uk)
GE (6) GEP20022802B (uk)
GR (1) GR3034579T3 (uk)
HK (3) HK1019753A1 (uk)
HU (1) HUT66097A (uk)
LV (1) LV12618B (uk)
NO (6) NO307301B1 (uk)
RU (4) RU2210574C2 (uk)
SG (7) SG88783A1 (uk)
SK (4) SK282186B6 (uk)
UA (4) UA41875C2 (uk)
WO (1) WO1993005064A1 (uk)

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CN110974840A (zh) * 2019-12-27 2020-04-10 天津市肿瘤医院 一种类固醇硫酸酯酶抑制剂及其药物用途

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Also Published As

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HK1025051A1 (en) 2000-11-03
EP0928609A2 (en) 1999-07-14
AU689043B2 (en) 1998-03-19
NO308903B1 (no) 2000-11-13
NO20002595D0 (no) 2000-05-19
NO995075L (no) 1994-04-29
NO940635L (uk) 1994-04-29
BR9206434A (pt) 1994-09-27
SK282188B6 (sk) 2001-12-03
DE69233020T2 (de) 2003-11-06
GEP20022802B (en) 2002-09-25
HUT66097A (en) 1994-09-28
ES2148178T3 (es) 2000-10-16
GEP20022766B (en) 2002-08-26
EP0641355A1 (en) 1995-03-08
EP0982032A3 (en) 2002-03-20
SK24694A3 (en) 1994-11-09
ATE239753T1 (de) 2003-05-15
CZ295939B6 (cs) 2005-12-14
ATE278704T1 (de) 2004-10-15
NO20044458L (no) 1994-04-29
EP0641355B1 (en) 2000-07-19
DK0928609T3 (da) 2003-07-21
CY2397B1 (en) 2004-09-10
SG103374A1 (en) 2004-04-29
AU5837396A (en) 1996-09-05
AU1007799A (en) 1999-03-04
DE69231280T2 (de) 2000-11-30
EP0928609A3 (en) 2001-11-07
RU2207134C2 (ru) 2003-06-27
JP3581820B2 (ja) 2004-10-27
CZ44094A3 (en) 1995-01-18
NO308774B1 (no) 2000-10-30
HU9400583D0 (en) 1994-05-30
CY2253B1 (en) 2003-07-04
DK0921130T3 (da) 2003-07-21
FI20002259A (fi) 2000-10-13
US5616574A (en) 1997-04-01
RU2210574C2 (ru) 2003-08-20
EP1099706A2 (en) 2001-05-16
KR100322650B1 (ko) 2002-03-20
JP2003176297A (ja) 2003-06-24
AU668882B2 (en) 1996-05-23
GEP20022637B (en) 2002-02-25
EP1522543A1 (en) 2005-04-13
NO995076L (no) 1994-04-29
NO307301B1 (no) 2000-03-13
AU717116B2 (en) 2000-03-16
CA2114630A1 (en) 1993-03-18
SG88783A1 (en) 2002-05-21
CA2305749A1 (en) 1993-03-18
JP3219408B2 (ja) 2001-10-15
KR100321019B1 (ko) 2002-03-20
KR100258396B1 (ko) 2000-08-01
EP0921130A2 (en) 1999-06-09
ATE194843T1 (de) 2000-08-15
JP2000355542A (ja) 2000-12-26
FI20050991A (fi) 2005-10-03
WO1993005064A1 (en) 1993-03-18
ES2204059T3 (es) 2004-04-16
EP0921130B1 (en) 2003-05-07
JPH07501515A (ja) 1995-02-16
NO995075D0 (no) 1999-10-18
SG73391A1 (en) 2006-08-30
GR3034579T3 (en) 2001-01-31
ES2196483T3 (es) 2003-12-16
DE69233020D1 (de) 2003-05-22
CA2305758A1 (en) 1993-03-18
ATE246706T1 (de) 2003-08-15
CA2114630C (en) 2003-09-30
EP0982032B1 (en) 2003-08-06
DE69233053D1 (de) 2003-06-12
RU2001125673A (ru) 2003-06-27
CY2398B1 (en) 2004-09-10
EP0982032A2 (en) 2000-03-01
RU2182152C2 (ru) 2002-05-10
SK282189B6 (sk) 2001-12-03
JP3581821B2 (ja) 2004-10-27
DK0982032T3 (da) 2003-11-03
JP2000038341A (ja) 2000-02-08
SG106116A1 (en) 2004-09-30
FI940903A (fi) 1994-04-20
FI20002260A (fi) 2000-10-13
EP0921130A3 (en) 2001-09-05
GEP20033094B (en) 2003-10-27
GEP20022803B (en) 2002-09-25
SG115508A1 (en) 2005-10-28
US5830886A (en) 1998-11-03
HK1019753A1 (en) 2000-02-25
NO940635D0 (no) 1994-02-24
EP1099706B1 (en) 2004-10-06
NO20025725L (no) 1994-04-29
GEP20063773B (en) 2006-03-27
UA41875C2 (uk) 2001-10-15
JP3581802B2 (ja) 2004-10-27
ES2193475T3 (es) 2003-11-01
RU94019334A (ru) 1996-10-20
UA70958C2 (uk) 2004-11-15
FI940903A0 (fi) 1994-02-25
NO995076D0 (no) 1999-10-18
UA70956C2 (uk) 2004-11-15
DE69233431D1 (de) 2004-11-11
DK0641355T3 (da) 2000-10-09
GB9118478D0 (en) 1991-10-16
SG88782A1 (en) 2002-05-21
NO2595A (no) 1994-04-29
LV12618A (en) 2001-02-20
SG103820A1 (en) 2004-05-26
SK282187B6 (sk) 2001-12-03
ATE237333T1 (de) 2003-05-15
JP2000355598A (ja) 2000-12-26
CA2305767A1 (en) 1993-03-18
DE69233053T2 (de) 2003-11-20
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US6159960A (en) 2000-12-12

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