LV12618B - USE OF SULPHAMAT DERIVATIVES FOR STEROIDE SULPHATE INHIBITORS - Google Patents

USE OF SULPHAMAT DERIVATIVES FOR STEROIDE SULPHATE INHIBITORS Download PDF

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Publication number
LV12618B
LV12618B LVP-00-131A LV000131A LV12618B LV 12618 B LV12618 B LV 12618B LV 000131 A LV000131 A LV 000131A LV 12618 B LV12618 B LV 12618B
Authority
LV
Latvia
Prior art keywords
oestrone
compound
sulphamate
group
use according
Prior art date
Application number
LVP-00-131A
Other languages
English (en)
Latvian (lv)
Other versions
LV12618A (en
Inventor
Michael John Reed
Barry Victor Lloyd Potter
Original Assignee
Sterix Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterix Limited filed Critical Sterix Limited
Publication of LV12618A publication Critical patent/LV12618A/xx
Publication of LV12618B publication Critical patent/LV12618B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/36—Antigestagens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Surgical Instruments (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
LVP-00-131A 1991-08-29 2000-10-03 USE OF SULPHAMAT DERIVATIVES FOR STEROIDE SULPHATE INHIBITORS LV12618B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919118478A GB9118478D0 (en) 1991-08-29 1991-08-29 Steroid sulphatase inhibitors

Publications (2)

Publication Number Publication Date
LV12618A LV12618A (en) 2001-02-20
LV12618B true LV12618B (en) 2001-07-20

Family

ID=10700604

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-00-131A LV12618B (en) 1991-08-29 2000-10-03 USE OF SULPHAMAT DERIVATIVES FOR STEROIDE SULPHATE INHIBITORS

Country Status (26)

Country Link
US (3) US5616574A (uk)
EP (6) EP0921130B1 (uk)
JP (6) JP3219408B2 (uk)
KR (4) KR100258396B1 (uk)
AT (5) ATE278704T1 (uk)
AU (2) AU689043B2 (uk)
BR (1) BR9206434A (uk)
CA (4) CA2305758A1 (uk)
CY (4) CY2253B1 (uk)
CZ (1) CZ295939B6 (uk)
DE (5) DE69233020T2 (uk)
DK (4) DK0921130T3 (uk)
ES (4) ES2193475T3 (uk)
FI (5) FI940903A (uk)
GB (1) GB9118478D0 (uk)
GE (6) GEP20063773B (uk)
GR (1) GR3034579T3 (uk)
HK (3) HK1019753A1 (uk)
HU (1) HUT66097A (uk)
LV (1) LV12618B (uk)
NO (6) NO307301B1 (uk)
RU (4) RU2210574C2 (uk)
SG (7) SG115508A1 (uk)
SK (4) SK282189B6 (uk)
UA (4) UA41875C2 (uk)
WO (1) WO1993005064A1 (uk)

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US5763432A (en) * 1997-01-29 1998-06-09 Sri International Steriod inhibitors of estrone sulfatase and associated pharmaceutical compositions and methods of use
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US6248780B1 (en) * 1998-10-01 2001-06-19 Duquesne University Of The Holy Ghost Compounds for the treatment of estrogen-dependent illnesses and methods for making and using the same
US6667299B1 (en) 2000-03-16 2003-12-23 Hollis-Eden Pharmaceuticals, Inc. Pharmaceutical compositions and treatment methods
WO2000053620A1 (fr) * 1999-03-10 2000-09-14 Nippon Organon K. K. Nouveaux derives d'oestradiol
JP2000309599A (ja) 1999-04-13 2000-11-07 Kyowa Hakko Kogyo Co Ltd エストラ−１，３，５（１０），１６−テトラエン誘導体
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US7078395B1 (en) 1999-06-16 2006-07-18 Sterix Limited Methods for treating or preventing cancer by preventing, inhibiting or arresting cell cycling
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DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
US8026229B2 (en) 2001-08-13 2011-09-27 Sterix Limited Antitumor-active 2-alkoxyestradiol sulfamates
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ES2258174T3 (es) 2001-10-18 2006-08-16 Sterix Limited Compuestos esteroideos para la inhibicion de la sulfatasa esteroidea.
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US20040254241A1 (en) * 2002-08-28 2004-12-16 Yoji Ino Aryl sulfamate derivatives
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GB0624105D0 (en) * 2006-12-01 2007-01-10 Sterix Ltd Use
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PT2398500T (pt) 2009-02-20 2019-06-14 2 Bbb Medicines B V Sistema de entrega de medicamentos à base de glutationas
TWI556839B (zh) 2009-05-06 2016-11-11 研究室護膚股份有限公司 包含活性劑－磷酸鈣粒子複合物之皮膚遞送組成物及其使用方法
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Also Published As

Publication number Publication date
EP1522543A1 (en) 2005-04-13
EP1099706B1 (en) 2004-10-06
NO20044458L (no) 1994-04-29
CY2397B1 (en) 2004-09-10
UA41875C2 (uk) 2001-10-15
CZ44094A3 (en) 1995-01-18
BR9206434A (pt) 1994-09-27
DE69233431T2 (de) 2006-02-23
ES2193475T3 (es) 2003-11-01
HK1025051A1 (en) 2000-11-03
FI940903A0 (fi) 1994-02-25
FI940903A (fi) 1994-04-20
SG106116A1 (en) 2004-09-30
GEP20033094B (en) 2003-10-27
GB9118478D0 (en) 1991-10-16
RU2207134C2 (ru) 2003-06-27
JPH07501515A (ja) 1995-02-16
EP0921130A2 (en) 1999-06-09
DE69233149D1 (de) 2003-09-11
EP0928609B1 (en) 2003-04-16
JP3219408B2 (ja) 2001-10-15
JP2000355598A (ja) 2000-12-26
NO995075D0 (no) 1999-10-18
EP0982032A2 (en) 2000-03-01
GEP20022766B (en) 2002-08-26
GR3034579T3 (en) 2001-01-31
GEP20022802B (en) 2002-09-25
NO314287B1 (no) 2003-03-03
LV12618A (en) 2001-02-20
DK0982032T3 (da) 2003-11-03
EP0928609A2 (en) 1999-07-14
SG103374A1 (en) 2004-04-29
DE69233020T2 (de) 2003-11-06
EP0928609A3 (en) 2001-11-07
SG88783A1 (en) 2002-05-21
HUT66097A (en) 1994-09-28
ATE237333T1 (de) 2003-05-15
KR100321019B1 (ko) 2002-03-20
NO2595A (no) 1994-04-29
SG115508A1 (en) 2005-10-28
NO995076D0 (no) 1999-10-18
GEP20063773B (en) 2006-03-27
JP3581821B2 (ja) 2004-10-27
FI20002260A (fi) 2000-10-13
NO20002595D0 (no) 2000-05-19
NO308774B1 (no) 2000-10-30
SG88782A1 (en) 2002-05-21
RU2210574C2 (ru) 2003-08-20
KR100322650B1 (ko) 2002-03-20
UA70956C2 (uk) 2004-11-15
NO940635D0 (no) 1994-02-24
AU5837396A (en) 1996-09-05
GEP20022803B (en) 2002-09-25
KR100321018B1 (ko) 2002-03-20
DE69231280D1 (de) 2000-08-24
CY2394B1 (en) 2004-09-10
EP0641355A1 (en) 1995-03-08
NO308903B1 (no) 2000-11-13
AU717116B2 (en) 2000-03-16
WO1993005064A1 (en) 1993-03-18
CY2253B1 (en) 2003-07-04
HK1020672A1 (en) 2000-05-19
JP2003176297A (ja) 2003-06-24
EP0982032A3 (en) 2002-03-20
JP2002255993A (ja) 2002-09-11
SK282189B6 (sk) 2001-12-03
ATE278704T1 (de) 2004-10-15
NO995075L (no) 1994-04-29
SK282187B6 (sk) 2001-12-03
EP0921130A3 (en) 2001-09-05
SG73391A1 (en) 2006-08-30
NO940635L (uk) 1994-04-29
ES2204059T3 (es) 2004-04-16
DE69233431D1 (de) 2004-11-11
DK0641355T3 (da) 2000-10-09
US5830886A (en) 1998-11-03
CA2305758A1 (en) 1993-03-18
EP0641355B1 (en) 2000-07-19
ES2148178T3 (es) 2000-10-16
GEP20022637B (en) 2002-02-25
NO307301B1 (no) 2000-03-13
SK24694A3 (en) 1994-11-09
CA2305749A1 (en) 1993-03-18
NO20025725D0 (no) 2002-11-28
DE69233149T2 (de) 2004-06-24
US6159960A (en) 2000-12-12
ATE246706T1 (de) 2003-08-15
FI20050991A (fi) 2005-10-03
JP2000355542A (ja) 2000-12-26
FI20002259A (fi) 2000-10-13
ATE239753T1 (de) 2003-05-15
RU94019334A (ru) 1996-10-20
UA70958C2 (uk) 2004-11-15
CY2398B1 (en) 2004-09-10
HK1019753A1 (en) 2000-02-25
NO20025725L (no) 1994-04-29
SG103820A1 (en) 2004-05-26
ES2196483T3 (es) 2003-12-16
DK0928609T3 (da) 2003-07-21
HU9400583D0 (en) 1994-05-30
ATE194843T1 (de) 2000-08-15
AU2490592A (en) 1993-04-05
SK282188B6 (sk) 2001-12-03
US5616574A (en) 1997-04-01
JP2000038341A (ja) 2000-02-08
JP3581802B2 (ja) 2004-10-27
RU2182152C2 (ru) 2002-05-10
DE69231280T2 (de) 2000-11-30
NO318009B1 (no) 2005-01-17
CA2114630C (en) 2003-09-30
EP1099706A3 (en) 2002-09-04
DE69233020D1 (de) 2003-05-22
NO995076L (no) 1994-04-29
UA70957C2 (uk) 2004-11-15
AU668882B2 (en) 1996-05-23
EP1099706A2 (en) 2001-05-16
CZ295939B6 (cs) 2005-12-14
DE69233053T2 (de) 2003-11-20
DK0921130T3 (da) 2003-07-21
FI20002261A (fi) 2000-10-13
DE69233053D1 (de) 2003-06-12
EP0921130B1 (en) 2003-05-07
CA2114630A1 (en) 1993-03-18
KR100258396B1 (ko) 2000-08-01
EP0982032B1 (en) 2003-08-06
JP3581820B2 (ja) 2004-10-27
CA2305767A1 (en) 1993-03-18
AU689043B2 (en) 1998-03-19
AU1007799A (en) 1999-03-04
SK282186B6 (sk) 2001-12-03
RU2001125673A (ru) 2003-06-27

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