SK281826B6 - Deriváty fosfolipidov nukleozidov, ich použitie a farmaceutický prostriedok na ich báze - Google Patents

Deriváty fosfolipidov nukleozidov, ich použitie a farmaceutický prostriedok na ich báze Download PDF

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Publication number
SK281826B6
SK281826B6 SK92-93A SK9293A SK281826B6 SK 281826 B6 SK281826 B6 SK 281826B6 SK 9293 A SK9293 A SK 9293A SK 281826 B6 SK281826 B6 SK 281826B6
Authority
SK
Slovakia
Prior art keywords
phosphoric acid
dodecylmercapto
decyloxy
desoxy
propyl ester
Prior art date
Application number
SK92-93A
Other languages
English (en)
Slovak (sk)
Other versions
SK9293A3 (en
Inventor
Harald Zilch
Herbert Leinert
Alfred Mertens
Dieter Hermann
Original Assignee
Roche Diagnostics Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25896049&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SK281826(B6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Roche Diagnostics Gmbh filed Critical Roche Diagnostics Gmbh
Publication of SK9293A3 publication Critical patent/SK9293A3/sk
Publication of SK281826B6 publication Critical patent/SK281826B6/sk

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • C07H19/10Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • C07H19/20Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • C12P19/28N-glycosides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
SK92-93A 1990-08-20 1991-08-14 Deriváty fosfolipidov nukleozidov, ich použitie a farmaceutický prostriedok na ich báze SK281826B6 (sk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4026265A DE4026265A1 (de) 1990-08-20 1990-08-20 Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel
PCT/EP1991/001541 WO1992003462A1 (de) 1990-08-20 1991-08-14 Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel
US08/661,038 US5756711A (en) 1990-08-20 1996-06-10 Phospholipid derivatives of nucleosides and their use as anti-viral medicaments

Publications (2)

Publication Number Publication Date
SK9293A3 SK9293A3 (en) 1993-07-07
SK281826B6 true SK281826B6 (sk) 2001-08-06

Family

ID=25896049

Family Applications (1)

Application Number Title Priority Date Filing Date
SK92-93A SK281826B6 (sk) 1990-08-20 1991-08-14 Deriváty fosfolipidov nukleozidov, ich použitie a farmaceutický prostriedok na ich báze

Country Status (15)

Country Link
US (1) US5756711A (es)
EP (1) EP0545966B1 (es)
CN (1) CN1032258C (es)
AT (1) ATE114316T1 (es)
CA (1) CA2090024C (es)
DE (2) DE4026265A1 (es)
DK (1) DK0545966T3 (es)
ES (1) ES2066461T3 (es)
FI (1) FI104176B (es)
HK (1) HK35597A (es)
IE (1) IE64374B1 (es)
NO (1) NO179710C (es)
PT (1) PT98720B (es)
SK (1) SK281826B6 (es)
WO (1) WO1992003462A1 (es)

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DE4226279A1 (de) * 1992-08-08 1994-02-10 Boehringer Mannheim Gmbh Liponucleotide von Seco-Nucleosiden, deren Herstellung sowie deren Verwendung als antivirale Arzneimittel
US6080734A (en) * 1992-08-08 2000-06-27 Roche Diagnostic Gmbh Liponucleotides of seco-nucleosides, their production as well as their use as antiviral pharmaceutical agents
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US7135584B2 (en) 1995-08-07 2006-11-14 Wake Forest University Lipid analogs for treating viral infections
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DE19547022A1 (de) * 1995-12-15 1997-06-19 Boehringer Mannheim Gmbh Kovalente Lipid-Phosphonocarbonsäure-Konjugate, deren Herstellung sowie deren Verwendung als antivirale Arzneimittel
DE19602757A1 (de) 1996-01-26 1997-07-31 Boehringer Mannheim Gmbh Feste Instant-Release-Darreichungsformen und Verfahren zu ihrer Herstellung
US7026469B2 (en) * 2000-10-19 2006-04-11 Wake Forest University School Of Medicine Compositions and methods of double-targeting virus infections and cancer cells
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US9512125B2 (en) * 2004-11-19 2016-12-06 The Regents Of The University Of California Substituted pyrazolo[3.4-D] pyrimidines as anti-inflammatory agents
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Also Published As

Publication number Publication date
CN1032258C (zh) 1996-07-10
US5756711A (en) 1998-05-26
IE64374B1 (en) 1995-07-26
DK0545966T3 (da) 1995-05-08
CN1059149A (zh) 1992-03-04
NO179710C (no) 1996-12-04
FI930753A0 (fi) 1993-02-19
WO1992003462A1 (de) 1992-03-05
NO179710B (no) 1996-08-26
FI930753A (fi) 1993-02-19
ES2066461T3 (es) 1995-03-01
CA2090024A1 (en) 1992-02-21
IE912930A1 (en) 1992-02-26
AU654670B2 (en) 1994-11-17
AU8325191A (en) 1992-03-17
ATE114316T1 (de) 1994-12-15
PT98720A (pt) 1992-07-31
FI104176B1 (fi) 1999-11-30
HK35597A (en) 1997-03-27
NO930587D0 (no) 1993-02-19
DE59103595D1 (de) 1995-01-05
SK9293A3 (en) 1993-07-07
DE4026265A1 (de) 1992-02-27
NO930587L (no) 1993-02-19
EP0545966B1 (de) 1994-11-23
EP0545966A1 (de) 1993-06-16
PT98720B (pt) 1999-02-26
FI104176B (fi) 1999-11-30
CA2090024C (en) 2000-05-02

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MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20090814