SK281761B6 - Fenylindolová zlúčenina, farmaceutický prostriedok s jej obsahom a jej použitie - Google Patents

Fenylindolová zlúčenina, farmaceutický prostriedok s jej obsahom a jej použitie Download PDF

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Publication number
SK281761B6
SK281761B6 SK534-96A SK53496A SK281761B6 SK 281761 B6 SK281761 B6 SK 281761B6 SK 53496 A SK53496 A SK 53496A SK 281761 B6 SK281761 B6 SK 281761B6
Authority
SK
Slovakia
Prior art keywords
fluorophenyl
chloro
ethyl
piperidin
indol
Prior art date
Application number
SK534-96A
Other languages
English (en)
Slovak (sk)
Other versions
SK53496A3 (en
Inventor
Jens Perregaard
Ejner Knud Moltzen
Kim Andersen
Henrik Pedersen
Klaus Peter Bogeso
Andre Pernet
Barbara Bopp
Darcy Mulford
Kiyoshi Sakamoto
Original Assignee
H. Lundbeck A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H. Lundbeck A/S filed Critical H. Lundbeck A/S
Publication of SK53496A3 publication Critical patent/SK53496A3/sk
Publication of SK281761B6 publication Critical patent/SK281761B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Sewing Machines And Sewing (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
SK534-96A 1993-11-01 1994-10-28 Fenylindolová zlúčenina, farmaceutický prostriedok s jej obsahom a jej použitie SK281761B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK931234A DK123493D0 (da) 1993-11-01 1993-11-01 Compounds
PCT/DK1994/000407 WO1995012591A1 (fr) 1993-11-01 1994-10-28 Composes de phenylindole

Publications (2)

Publication Number Publication Date
SK53496A3 SK53496A3 (en) 1996-11-06
SK281761B6 true SK281761B6 (sk) 2001-07-10

Family

ID=8102507

Family Applications (1)

Application Number Title Priority Date Filing Date
SK534-96A SK281761B6 (sk) 1993-11-01 1994-10-28 Fenylindolová zlúčenina, farmaceutický prostriedok s jej obsahom a jej použitie

Country Status (27)

Country Link
US (1) US5703087A (fr)
EP (1) EP0726898B1 (fr)
JP (1) JP3898219B2 (fr)
KR (1) KR100350550B1 (fr)
CN (1) CN1134149A (fr)
AT (1) ATE198199T1 (fr)
AU (1) AU683700B2 (fr)
CA (1) CA2175498C (fr)
CZ (1) CZ291403B6 (fr)
DE (1) DE69426462T2 (fr)
DK (2) DK123493D0 (fr)
ES (1) ES2154303T3 (fr)
FI (1) FI116623B (fr)
GR (1) GR3035462T3 (fr)
HK (1) HK1013817A1 (fr)
HU (1) HUT76063A (fr)
IL (2) IL111395A (fr)
LV (1) LV12805B (fr)
NO (1) NO309038B1 (fr)
NZ (1) NZ275086A (fr)
PL (1) PL176391B1 (fr)
PT (1) PT726898E (fr)
RU (1) RU2156249C2 (fr)
SI (1) SI0726898T1 (fr)
SK (1) SK281761B6 (fr)
WO (1) WO1995012591A1 (fr)
ZA (1) ZA948589B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6489341B1 (en) 1999-06-02 2002-12-03 Sepracor Inc. Methods for the treatment of neuroleptic and related disorders using sertindole derivatives
AU6984600A (en) * 1999-09-09 2001-04-24 H. Lundbeck A/S 5-aminoalkyl and 5-aminocarbonyl substituted indoles
US20070212412A1 (en) * 2005-09-08 2007-09-13 H. Lundbeck A/S Stable solid formulation of sertindole
TW200821296A (en) * 2006-06-01 2008-05-16 Lundbeck & Co As H Use of sertindole for the preventive treatment of suicidal behaviour
ES2575215T3 (es) * 2009-12-11 2016-06-27 Autifony Therapeutics Limited Derivados de imidazolidindiona
EP2582698B1 (fr) * 2010-06-16 2016-09-14 Vitae Pharmaceuticals, Inc. Hétérocycles à 5, 6 et 7 chaînons substitués, médicaments contenant ces composés et leur utilisation
DK2649066T3 (en) 2010-12-06 2016-01-11 Autifony Therapeutics Ltd Hydantoin derivatives using as KV3 inhibitors.
US9193704B2 (en) 2011-06-07 2015-11-24 Autifony Therapeutics Limited Hydantoin derivatives as KV3 inhibitors
DK2788339T3 (en) * 2011-12-06 2016-05-23 Autifony Therapeutics Ltd HYDANTOIN DERIVATIVES, USEFUL AS QU3 INHIBITORS
EP2852588B8 (fr) 2012-05-22 2018-01-10 Autifony Therapeutics Limited Dérivés d'hydantoïne en tant qu'inhibiteurs de kv3
CN104334547B (zh) 2012-05-22 2017-06-06 奥蒂福尼疗法有限公司 作为kv3抑制剂的三唑类

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE58370B1 (en) * 1985-04-10 1993-09-08 Lundbeck & Co As H Indole derivatives
GB8908085D0 (en) * 1989-04-11 1989-05-24 Lundbeck & Co As H New therapeutic use
DK152090D0 (da) * 1990-06-22 1990-06-22 Lundbaek A S H Piperidylsubstituerede indolderivater

Also Published As

Publication number Publication date
NO961746L (no) 1996-06-28
NO961746D0 (no) 1996-04-30
KR960705814A (ko) 1996-11-08
PL314181A1 (en) 1996-08-19
ES2154303T3 (es) 2001-04-01
DE69426462D1 (de) 2001-01-25
CZ291403B6 (cs) 2003-03-12
DK0726898T3 (da) 2001-04-30
JPH09506083A (ja) 1997-06-17
JP3898219B2 (ja) 2007-03-28
RU2156249C2 (ru) 2000-09-20
CN1134149A (zh) 1996-10-23
CA2175498C (fr) 2005-07-26
AU8057794A (en) 1995-05-23
US5703087A (en) 1997-12-30
IL111394A0 (en) 1994-12-29
PL176391B1 (pl) 1999-05-31
FI116623B (fi) 2006-01-13
IL111395A (en) 1999-06-20
DE69426462T2 (de) 2001-04-26
EP0726898A1 (fr) 1996-08-21
WO1995012591A1 (fr) 1995-05-11
FI961844A (fi) 1996-04-30
HU9601144D0 (en) 1996-07-29
PT726898E (pt) 2001-05-31
IL111394A (en) 1998-08-16
GR3035462T3 (en) 2001-05-31
LV12805B (lv) 2002-05-20
NO309038B1 (no) 2000-12-04
SK53496A3 (en) 1996-11-06
DK123493D0 (da) 1993-11-01
SI0726898T1 (en) 2001-04-30
EP0726898B1 (fr) 2000-12-20
FI961844A0 (fi) 1996-04-30
HUT76063A (en) 1997-06-30
HK1013817A1 (en) 1999-09-10
IL111395A0 (en) 1994-12-29
ATE198199T1 (de) 2001-01-15
CA2175498A1 (fr) 1995-05-11
NZ275086A (en) 1997-10-24
AU683700B2 (en) 1997-11-20
LV12805A (en) 2002-03-20
ZA948589B (en) 1995-06-26
KR100350550B1 (ko) 2002-12-12
CZ124896A3 (en) 1996-09-11

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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20091028