SK280578B6 - Derivát izatinoxímu, spôsob jeho prípravy, farmace - Google Patents
Derivát izatinoxímu, spôsob jeho prípravy, farmace Download PDFInfo
- Publication number
- SK280578B6 SK280578B6 SK238-94A SK23894A SK280578B6 SK 280578 B6 SK280578 B6 SK 280578B6 SK 23894 A SK23894 A SK 23894A SK 280578 B6 SK280578 B6 SK 280578B6
- Authority
- SK
- Slovakia
- Prior art keywords
- group
- isatinoxime
- branched
- formula
- derivative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Hydrogenated Pyridines (AREA)
- Medicinal Preparation (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75116591A | 1991-08-28 | 1991-08-28 | |
| US83185192A | 1992-02-05 | 1992-02-05 | |
| PCT/EP1992/001999 WO1993005043A1 (en) | 1991-08-28 | 1992-08-27 | Novel isatinoxime derivatives, their preparation and use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK23894A3 SK23894A3 (en) | 1994-12-07 |
| SK280578B6 true SK280578B6 (sk) | 2000-04-10 |
Family
ID=27115380
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK238-94A SK280578B6 (sk) | 1991-08-28 | 1992-08-27 | Derivát izatinoxímu, spôsob jeho prípravy, farmace |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0529636B1 (da) |
| JP (1) | JP3170584B2 (da) |
| KR (1) | KR100277481B1 (da) |
| AT (1) | ATE181552T1 (da) |
| AU (1) | AU655672B2 (da) |
| CA (1) | CA2076948C (da) |
| CZ (1) | CZ282759B6 (da) |
| DE (1) | DE69229461T2 (da) |
| DK (1) | DK0529636T3 (da) |
| FI (1) | FI107156B (da) |
| GE (1) | GEP20002329B (da) |
| HU (2) | HUT70753A (da) |
| MX (1) | MX9204914A (da) |
| NO (1) | NO301117B1 (da) |
| PL (1) | PL170920B1 (da) |
| RU (1) | RU2114827C1 (da) |
| SK (1) | SK280578B6 (da) |
| WO (1) | WO1993005043A1 (da) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08502483A (ja) | 1992-10-13 | 1996-03-19 | ワーナー−ランバート・コンパニー | 新規なキノキサリンジオン誘導体、それらの製造および使用 |
| JP3439215B2 (ja) * | 1993-05-13 | 2003-08-25 | ノイロサーチ アクティーゼルスカブ | Ａｍｐａ拮抗薬およびそれを用いての治療方法 |
| US5843945A (en) * | 1993-05-13 | 1998-12-01 | Neurosearch A/S | AMPA antagonists and a method of treatment |
| DK81593D0 (da) * | 1993-07-07 | 1993-07-07 | Neurosearch As | Nye isatinoximderivater, deres fremstilling og anvendelse |
| NZ293266A (en) * | 1994-09-14 | 1998-01-26 | Neurosearch As | Fused indole and quinoxaline dione and dione oxime derivatives, preparation and pharmaceutical compositions |
| JP3164371B2 (ja) * | 1994-09-14 | 2001-05-08 | ノイロサーチ アクティーゼルスカブ | インドール−２，３−ジオン−３−オキシム誘導体、その製造および使用 |
| UA54403C2 (uk) * | 1996-10-01 | 2003-03-17 | Н'Юросерч А/С | Похідні індол-2,3-діон-3-оксиму, фармацевтична композиція, спосіб лікування розладу чи захворювання ссавців, у тому числі людини та спосіб одержання похідних індол-2,3-діон-3-оксиму |
| FR2768624B1 (fr) | 1997-09-25 | 1999-11-12 | Oreal | Utilisation d'un inhibiteur d'acides amines excitateurs dans une composition cosmetique ou dermatologique pour peaux sensibles et composition obtenue |
| CA2369746A1 (en) * | 1999-05-19 | 2000-11-30 | Neurosearch A/S | Inhibitors of proton-gated cation channels and their use in the treatment of ischaemic disorders |
| ES2266214T3 (es) | 2000-01-24 | 2007-03-01 | Neurosearch A/S | Derivados de isatina con actividad neurotrofica. |
| WO2004039372A1 (en) | 2002-10-29 | 2004-05-13 | Sungkyunkwan University | Medicament component of berberine for the use of prevention and treatment of psycological dependence on and analgesic tolerance to morphine |
| CN101346375B (zh) | 2005-11-23 | 2013-04-10 | 阿罗斯药物有限责任公司 | 调节门离子通道用组合物和方法 |
| ES2739395T3 (es) | 2012-12-19 | 2020-01-30 | Bayer Cropscience Ag | Indanilcarboxamidas difluorometil-nicotínicas como fungicidas |
| JP6380524B2 (ja) * | 2014-02-28 | 2018-08-29 | 住友化学株式会社 | ２−（ハロゲノメチル）−３−メチルニトロベンゼンの製造方法 |
| US10570086B2 (en) | 2016-03-17 | 2020-02-25 | Fmc Corporation | Process for converting S-enantiomer to its racemic form |
| CN112266368B (zh) * | 2017-11-15 | 2024-03-19 | 中山光禾医疗科技有限公司 | 光交联水凝胶材料的制备、原料、产品及应用 |
| CN108912127B (zh) * | 2018-08-27 | 2019-12-10 | 青岛农业大学 | 一种基于靛红骨架的苯并[b,e]氮杂卓化合物及其制备方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE69677B1 (en) * | 1989-12-11 | 1996-10-02 | Neurosearch As | Isatine derivatives their preparation and use |
-
1992
- 1992-08-26 MX MX9204914A patent/MX9204914A/es not_active IP Right Cessation
- 1992-08-26 CA CA002076948A patent/CA2076948C/en not_active Expired - Fee Related
- 1992-08-27 AU AU24820/92A patent/AU655672B2/en not_active Ceased
- 1992-08-27 AT AT92114654T patent/ATE181552T1/de not_active IP Right Cessation
- 1992-08-27 WO PCT/EP1992/001999 patent/WO1993005043A1/en active IP Right Grant
- 1992-08-27 SK SK238-94A patent/SK280578B6/sk unknown
- 1992-08-27 JP JP50493393A patent/JP3170584B2/ja not_active Expired - Fee Related
- 1992-08-27 RU RU94019425/04A patent/RU2114827C1/ru not_active IP Right Cessation
- 1992-08-27 CZ CZ94395A patent/CZ282759B6/cs not_active IP Right Cessation
- 1992-08-27 PL PL92302584A patent/PL170920B1/pl unknown
- 1992-08-27 DK DK92114654T patent/DK0529636T3/da active
- 1992-08-27 GE GEAP19922683A patent/GEP20002329B/en unknown
- 1992-08-27 EP EP92114654A patent/EP0529636B1/en not_active Expired - Lifetime
- 1992-08-27 DE DE69229461T patent/DE69229461T2/de not_active Expired - Lifetime
- 1992-08-27 HU HU9400595A patent/HUT70753A/hu unknown
- 1992-08-27 KR KR1019940700676A patent/KR100277481B1/ko not_active IP Right Cessation
-
1994
- 1994-02-25 FI FI940889A patent/FI107156B/fi active
- 1994-02-25 NO NO940676A patent/NO301117B1/no unknown
-
1995
- 1995-06-21 HU HU95P/P00323P patent/HU211632A9/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO1993005043A1 (en) | 1993-03-18 |
| PL170920B1 (pl) | 1997-02-28 |
| RU2114827C1 (ru) | 1998-07-10 |
| DE69229461T2 (de) | 1999-10-21 |
| HU9400595D0 (en) | 1994-05-30 |
| AU655672B2 (en) | 1995-01-05 |
| FI107156B (fi) | 2001-06-15 |
| EP0529636B1 (en) | 1999-06-23 |
| CA2076948C (en) | 2002-04-16 |
| EP0529636A1 (en) | 1993-03-03 |
| CA2076948A1 (en) | 1993-03-01 |
| JP3170584B2 (ja) | 2001-05-28 |
| CZ282759B6 (cs) | 1997-09-17 |
| MX9204914A (es) | 1993-07-01 |
| NO940676L (da) | 1994-04-27 |
| HUT70753A (en) | 1995-10-30 |
| DK0529636T3 (da) | 1999-12-13 |
| ATE181552T1 (de) | 1999-07-15 |
| KR100277481B1 (ko) | 2001-02-01 |
| FI940889A (fi) | 1994-02-25 |
| AU2482092A (en) | 1993-04-05 |
| HU211632A9 (en) | 1995-12-28 |
| DE69229461D1 (de) | 1999-07-29 |
| JPH06510056A (ja) | 1994-11-10 |
| SK23894A3 (en) | 1994-12-07 |
| NO301117B1 (no) | 1997-09-15 |
| GEP20002329B (en) | 2000-12-25 |
| NO940676D0 (no) | 1994-02-25 |
| CZ39594A3 (en) | 1994-11-16 |
| FI940889A0 (fi) | 1994-02-25 |
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