MX9204914A - Nuevos derivados de isatinoxima, metodo para su preparacion y composicion farmaceutica que los comprende. - Google Patents

Nuevos derivados de isatinoxima, metodo para su preparacion y composicion farmaceutica que los comprende.

Info

Publication number
MX9204914A
MX9204914A MX9204914A MX9204914A MX9204914A MX 9204914 A MX9204914 A MX 9204914A MX 9204914 A MX9204914 A MX 9204914A MX 9204914 A MX9204914 A MX 9204914A MX 9204914 A MX9204914 A MX 9204914A
Authority
MX
Mexico
Prior art keywords
cyclic
branched
alkyl
hydrogen
isatinoxima
Prior art date
Application number
MX9204914A
Other languages
English (en)
Inventor
Frank Watjen
Bjarne H Dahl
Jorgen Drejer
Leif H Jensen
Original Assignee
Frank Watjen
Bjarne H Dahl
Jorgen Drejer
Leif H Jensen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Frank Watjen, Bjarne H Dahl, Jorgen Drejer, Leif H Jensen filed Critical Frank Watjen
Publication of MX9204914A publication Critical patent/MX9204914A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

La presente invención se refiere a derivados de indol-2,3-dion oxima, de anillo fusionado a un método de tratamiento que utiliza los mismos, a composiciones farmacéuticas que comprenden los compuestos y a un método para preparar los nuevos compuestos de la invención.
MX9204914A 1991-08-28 1992-08-26 Nuevos derivados de isatinoxima, metodo para su preparacion y composicion farmaceutica que los comprende. MX9204914A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75116591A 1991-08-28 1991-08-28
US83185192A 1992-02-05 1992-02-05

Publications (1)

Publication Number Publication Date
MX9204914A true MX9204914A (es) 1993-07-01

Family

ID=27115380

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9204914A MX9204914A (es) 1991-08-28 1992-08-26 Nuevos derivados de isatinoxima, metodo para su preparacion y composicion farmaceutica que los comprende.

Country Status (18)

Country Link
EP (1) EP0529636B1 (es)
JP (1) JP3170584B2 (es)
KR (1) KR100277481B1 (es)
AT (1) ATE181552T1 (es)
AU (1) AU655672B2 (es)
CA (1) CA2076948C (es)
CZ (1) CZ282759B6 (es)
DE (1) DE69229461T2 (es)
DK (1) DK0529636T3 (es)
FI (1) FI107156B (es)
GE (1) GEP20002329B (es)
HU (2) HUT70753A (es)
MX (1) MX9204914A (es)
NO (1) NO301117B1 (es)
PL (1) PL170920B1 (es)
RU (1) RU2114827C1 (es)
SK (1) SK280578B6 (es)
WO (1) WO1993005043A1 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0664807B1 (en) 1992-10-13 1997-09-10 Warner-Lambert Company Quinoxalinedione derivatives as eaa antagonists
US5843945A (en) * 1993-05-13 1998-12-01 Neurosearch A/S AMPA antagonists and a method of treatment
ATE161259T1 (de) * 1993-05-13 1998-01-15 Neurosearch As Ampa antagonisten und behandlungsmethode
DK81593D0 (da) * 1993-07-07 1993-07-07 Neurosearch As Nye isatinoximderivater, deres fremstilling og anvendelse
DE69514533T2 (de) * 1994-09-14 2000-07-06 Neurosearch A/S, Ballerup Kondensierte indole und chinoxalinderivate, ihre herstellung und verwendung als glutamatantagonisten
US5917053A (en) * 1994-09-14 1999-06-29 Neurosearch A/S Indole-2,3-dione-3-oxime derivatives, their preparation and use
UA54403C2 (uk) * 1996-10-01 2003-03-17 Н'Юросерч А/С Похідні індол-2,3-діон-3-оксиму, фармацевтична композиція, спосіб лікування розладу чи захворювання ссавців, у тому числі людини та спосіб одержання похідних індол-2,3-діон-3-оксиму
FR2768624B1 (fr) * 1997-09-25 1999-11-12 Oreal Utilisation d'un inhibiteur d'acides amines excitateurs dans une composition cosmetique ou dermatologique pour peaux sensibles et composition obtenue
ATE420636T1 (de) 1999-05-19 2009-01-15 Painceptor Pharma Corp Hemmer der protonenabhängigen kationenkanäle und deren verwendung in der behandlung von ischemiebedingten erkrankungen
CN1298704C (zh) 2000-01-24 2007-02-07 神经研究公司 具有神经营养活性的靛红衍生物
JP4505410B2 (ja) 2002-10-29 2010-07-21 サングキュンクワン ユニヴァースィティ モルヒネへの心理的依存又は耐性を防止及び処置するのに有効成分としてベルベリンを含有する医薬組成物
CA2630617C (en) 2005-11-23 2014-03-25 Painceptor Pharma Corporation Compositions and methods for modulating gated ion channels
CN104995171B (zh) * 2012-12-19 2018-02-06 拜耳作物科学股份公司 作为杀真菌剂的二氟甲基‑烟碱‑茚满基甲酰胺
US9815768B2 (en) * 2014-02-28 2017-11-14 Sumitomo Chemical Company, Limited Method for producing 2-(halogenomethyl)-3-methylnitrobenzene
WO2017160933A1 (en) 2016-03-17 2017-09-21 Fmc Corporation Process for converting s-enantiomer to its racemic form
CN112266368B (zh) * 2017-11-15 2024-03-19 中山光禾医疗科技有限公司 光交联水凝胶材料的制备、原料、产品及应用
CN108912127B (zh) * 2018-08-27 2019-12-10 青岛农业大学 一种基于靛红骨架的苯并[b,e]氮杂卓化合物及其制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE69677B1 (en) * 1989-12-11 1996-10-02 Neurosearch As Isatine derivatives their preparation and use

Also Published As

Publication number Publication date
AU655672B2 (en) 1995-01-05
GEP20002329B (en) 2000-12-25
CA2076948C (en) 2002-04-16
HU9400595D0 (en) 1994-05-30
DK0529636T3 (da) 1999-12-13
HUT70753A (en) 1995-10-30
EP0529636B1 (en) 1999-06-23
SK23894A3 (en) 1994-12-07
RU2114827C1 (ru) 1998-07-10
FI940889A0 (fi) 1994-02-25
ATE181552T1 (de) 1999-07-15
FI107156B (fi) 2001-06-15
KR100277481B1 (ko) 2001-02-01
JP3170584B2 (ja) 2001-05-28
NO940676D0 (no) 1994-02-25
EP0529636A1 (en) 1993-03-03
CZ39594A3 (en) 1994-11-16
DE69229461T2 (de) 1999-10-21
WO1993005043A1 (en) 1993-03-18
PL170920B1 (pl) 1997-02-28
DE69229461D1 (de) 1999-07-29
CA2076948A1 (en) 1993-03-01
NO940676L (es) 1994-04-27
FI940889A (fi) 1994-02-25
AU2482092A (en) 1993-04-05
CZ282759B6 (cs) 1997-09-17
SK280578B6 (sk) 2000-04-10
JPH06510056A (ja) 1994-11-10
NO301117B1 (no) 1997-09-15
HU211632A9 (en) 1995-12-28

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