SK12297A3 - Benzoxazoles, pyridine derivatives, process for producing same pharmaceutical composition containing them, their use and intermediate product - Google Patents
Benzoxazoles, pyridine derivatives, process for producing same pharmaceutical composition containing them, their use and intermediate product Download PDFInfo
- Publication number
- SK12297A3 SK12297A3 SK122-97A SK12297A SK12297A3 SK 12297 A3 SK12297 A3 SK 12297A3 SK 12297 A SK12297 A SK 12297A SK 12297 A3 SK12297 A3 SK 12297A3
- Authority
- SK
- Slovakia
- Prior art keywords
- pharmaceutically acceptable
- formula
- compound
- acceptable salt
- benzoxazolyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9415330A GB9415330D0 (en) | 1994-07-29 | 1994-07-29 | Novel compounds |
GBGB9425599.9A GB9425599D0 (en) | 1994-12-19 | 1994-12-19 | Novel compounds |
GBGB9509923.0A GB9509923D0 (en) | 1995-05-17 | 1995-05-17 | Novel compounds |
PCT/EP1995/003038 WO1996004260A1 (en) | 1994-07-29 | 1995-07-28 | Benzoxazoles and pyridine derivatives useful in the treatment of the type ii diabetes |
Publications (1)
Publication Number | Publication Date |
---|---|
SK12297A3 true SK12297A3 (en) | 1997-08-06 |
Family
ID=27267309
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SK122-97A SK12297A3 (en) | 1994-07-29 | 1995-07-28 | Benzoxazoles, pyridine derivatives, process for producing same pharmaceutical composition containing them, their use and intermediate product |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0772605A1 (cs) |
AP (1) | AP776A (cs) |
BR (1) | BR9508468A (cs) |
CA (1) | CA2196079A1 (cs) |
CZ (1) | CZ25497A3 (cs) |
DZ (1) | DZ1916A1 (cs) |
FI (1) | FI970357A (cs) |
HU (1) | HUT76637A (cs) |
IL (3) | IL125525A (cs) |
MA (1) | MA23632A1 (cs) |
MX (1) | MX9700763A (cs) |
NO (1) | NO307827B1 (cs) |
OA (1) | OA10470A (cs) |
PL (1) | PL318766A1 (cs) |
SK (1) | SK12297A3 (cs) |
WO (2) | WO1996004261A1 (cs) |
Families Citing this family (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9600464D0 (en) * | 1996-01-09 | 1996-03-13 | Smithkline Beecham Plc | Novel method |
RU2169141C2 (ru) * | 1996-04-04 | 2001-06-20 | Санкио Компани Лимитед | Производные фенилалкилкарбоновой кислоты и фармацевтическая композиция на их основе |
US6090839A (en) * | 1996-12-23 | 2000-07-18 | Merck & Co., Inc. | Antidiabetic agents |
US6160000A (en) * | 1996-12-23 | 2000-12-12 | Merck & Co., Inc. | Antidiabetic agents based on aryl and heteroarylacetic acids |
TR200000896T2 (tr) | 1997-10-02 | 2000-09-21 | Sankyo Company Limited | Amidokarboksilik asit türevleri. |
US6265401B1 (en) | 1997-10-27 | 2001-07-24 | Reddy-Cheminor, Inc. | Bicyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them |
US6440961B1 (en) | 1997-10-27 | 2002-08-27 | Dr. Reddy's Research Foundation | Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them |
GB2364304B (en) * | 1997-10-27 | 2003-04-23 | Reddy Research Foundation | Novel tricyclic compounds and their use in medicine process for their preparation and pharmaceutical compositions containing them |
US6444816B1 (en) | 1997-10-27 | 2002-09-03 | Dr. Reddy's Research Foundation | Fused 7-oxo-pyrimidinyl compounds, preparation, composition and use thereof |
RU2247722C2 (ru) | 1997-10-27 | 2005-03-10 | Др. Редди`З Лабораториз Лимитед | Производные арилкарбоновых кислот, способы их получения, фармацевтическая композиция на их основе, способы лечения и предупреждения различных заболеваний, промежуточные соединения и способы их получения |
US6369067B1 (en) | 1997-10-27 | 2002-04-09 | Dr. Reddy's Research Foundation | Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them |
WO1999016758A1 (en) * | 1997-10-27 | 1999-04-08 | Dr. Reddy's Research Foundation | Novel heterocyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them |
WO1999019313A1 (en) * | 1997-10-27 | 1999-04-22 | Dr. Reddy's Research Foundation | Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them |
JP2002507543A (ja) * | 1998-05-27 | 2002-03-12 | ドクター・レディーズ・リサーチ・ファウンデーション | 二環系化合物、その製造方法およびそれらを含有する薬学的組成物 |
CN1317970A (zh) | 1998-09-17 | 2001-10-17 | 布里斯托尔-迈尔斯斯奎布公司 | 用aP2抑制剂和组合剂治疗动脉粥样硬化的方法 |
JP2002527503A (ja) * | 1998-10-21 | 2002-08-27 | ノボ ノルディスク アクティーゼルスカブ | 新規化合物類、それらの調製及び使用 |
US6365586B1 (en) | 1998-10-21 | 2002-04-02 | Novo Nordisk A/S | Compounds, their preparation and use |
AU6325799A (en) * | 1998-10-21 | 2000-05-08 | Dr. Reddy's Research Foundation | New compounds, their preparation and use |
US6300339B1 (en) | 1998-10-21 | 2001-10-09 | Novo Nordisk A/S | Compounds, their preparation and use |
US6214820B1 (en) | 1998-10-21 | 2001-04-10 | Novo Nordisk A/S | Compounds, their preparation and use |
WO2000023416A1 (en) * | 1998-10-21 | 2000-04-27 | Novo Nordisk A/S | New compounds, their preparation and use |
AU6190199A (en) | 1998-10-21 | 2000-05-08 | Dr. Reddy's Research Foundation | New compounds, their preparation and use |
JP2002527516A (ja) * | 1998-10-21 | 2002-08-27 | ノボ ノルディスク アクティーゼルスカブ | 新規化合物、それらの製造及び使用 |
US6248781B1 (en) | 1998-10-21 | 2001-06-19 | Novo Nordisk A/S | Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR) |
US6468996B1 (en) | 1998-10-21 | 2002-10-22 | Novo Nordisk A/S | Substituted hetero-polycyclic compounds as PPARα and PPARγ activators |
JP2002527507A (ja) * | 1998-10-21 | 2002-08-27 | ノボ ノルディスク アクティーゼルスカブ | 新規化合物類、それらの調製及び使用 |
NZ510904A (en) * | 1998-10-29 | 2003-08-29 | Dr | An process for the preparation of antidiabetic agents |
US6531596B1 (en) | 1998-10-29 | 2003-03-11 | Dr. Reddy's Laboratories Ltd. | Process for the preparation of new antidiabetic agents |
AU3957800A (en) * | 1999-04-16 | 2000-11-02 | Dr. Reddy's Research Foundation | Crystalline r- guanidines, arginine or (l) -arginine (2(s)) -2- ethoxy -3-(4- (2-(10(h) -phenoxazin -10-yl)ethoxy}phenyl)propanoate |
US6972294B1 (en) | 1999-04-20 | 2005-12-06 | Novo Nordisk, A/S | Compounds, their preparation and use |
JP2002542246A (ja) | 1999-04-20 | 2002-12-10 | ノボ ノルディスク アクティーゼルスカブ | 新規な化合物、それらの製造及び使用 |
US7414128B2 (en) | 1999-04-20 | 2008-08-19 | Dr. Reddy's Laboratories, Limited | Crystalline R-guanidines, Arginine or (L)-Arginine (2S)-2-Ethoxy-3-{4-[2-(10H -phenoxazin-10-yl)ethoxy]phenyl}propanoate |
IL145789A0 (en) * | 1999-04-20 | 2002-07-25 | Novo Nordisk As | Derivatives of propionic acid, their preparation and pharmaceutical compositions containing them |
AU3957900A (en) * | 1999-04-20 | 2000-11-02 | Novo Nordisk A/S | New compounds, their preparation and use |
US6369055B1 (en) | 1999-04-20 | 2002-04-09 | Novo Nordisk A/S | Compounds, their preparation and use |
US6274608B1 (en) | 1999-04-20 | 2001-08-14 | Novo Nordisk A/S | Compounds, their preparation and use |
IL146104A0 (en) * | 1999-04-28 | 2002-07-25 | Reddy Research Foundation | Substituted bicyclic heterocyclic compounds, processes for their preparation and pharmaceutical compositions containing the same |
AU7073400A (en) | 1999-08-27 | 2001-03-26 | Eli Lilly And Company | Biaryl-oxa(thia)zole derivatives and their use as ppars modulators |
DZ3279A1 (fr) * | 2000-01-19 | 2001-07-26 | Cadila Healthcare Ltd | Nouveaux composes ayant des activites hypolipidemiques et hypocholesterolemiques, procede pour leur preparation et compositions pharmaceutiques les contenant |
US6555577B1 (en) | 2000-01-28 | 2003-04-29 | Novo Nordisk A/S | Compounds, their preparation and use |
US6569901B2 (en) | 2000-01-28 | 2003-05-27 | Novo Nordisk A/S | Alkynyl-substituted propionic acid derivatives, their preparation and use |
KR20020090211A (ko) * | 2000-01-28 | 2002-11-30 | 노보 노르디스크 에이/에스 | 알키닐 치환된 프로피온산 유도체 및 당뇨병 및 비만에대한 그것의 사용 |
US6509374B2 (en) | 2000-04-17 | 2003-01-21 | Novo Nordisk A/S | Compounds, their preparation and use |
AU2001263083A1 (en) | 2000-05-12 | 2001-11-26 | Ortho-Mcneil Pharmaceutical, Inc. | Biologically active 4h-benzo(1,4)oxazin-3-ones |
WO2001087860A2 (en) * | 2000-05-12 | 2001-11-22 | Ortho-Mcneil Pharmaceutical, Inc. | Novel benzoxazinones as peroxisome proliferator activated receptor gamma modulators and method of treatment |
US6908908B2 (en) | 2000-05-12 | 2005-06-21 | Ortho-Mcneil Pharmaceutical, Inc. | Biologically active 4H-benzo [1,4] oxazin-3-ones |
WO2001087861A2 (en) * | 2000-05-12 | 2001-11-22 | Ortho-Mcneil Pharmaceutical, Inc. | Methods of treatment using benzoxazinones as peroxisome proliferator activated receptor gamma modulators |
US6987123B2 (en) * | 2001-07-26 | 2006-01-17 | Cadila Healthcare Limited | Heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine |
US6869967B2 (en) | 2001-07-30 | 2005-03-22 | Novo Nordisk A/S | Peroxisome proliferator-activated receptor (PPAR) active vinyl carboxylic acid derivatives |
US7067530B2 (en) | 2001-07-30 | 2006-06-27 | Novo Nordisk A/S | Compounds, their preparation and use |
US7220877B2 (en) | 2001-10-17 | 2007-05-22 | Novo Nordisk A/S | Compounds, their preparation and use |
WO2003059378A2 (en) | 2001-12-29 | 2003-07-24 | Novo Nordisk A/S | Combined use of a glp-1 compound and another drug for treating dyslipidemia |
US7015345B2 (en) | 2002-02-21 | 2006-03-21 | Asahi Kasei Pharma Corporation | Propionic acid derivatives |
US7816385B2 (en) | 2002-12-20 | 2010-10-19 | High Point Pharmaceuticals, Llc | Dimeric dicarboxylic acid derivatives, their preparation and use |
US6653334B1 (en) | 2002-12-27 | 2003-11-25 | Kowa Co., Ltd. | Benzoxazole compound and pharmaceutical composition containing the same |
EP2154131A4 (en) * | 2007-04-26 | 2011-09-21 | Pharmafrontier Co Ltd | INHIBITOR OF THE G-PROTEIN-COUPLED RECEPTOR AND PHARMACEUTICAL PRODUCT |
CA2825456C (en) | 2011-01-31 | 2016-01-05 | Cadila Healthcare Limited | Treatment for lipodystrophy |
WO2014174524A1 (en) | 2013-04-22 | 2014-10-30 | Cadila Healthcare Limited | A novel composition for nonalcoholic fatty liver disease (nafld) |
MX2015016403A (es) | 2013-05-30 | 2016-04-11 | Cadila Healthcare Ltd | Proceso para la preparacion de pirroles que tienen actividad hipolipidemica e hipocolesterolemica. |
TW201636015A (zh) | 2013-07-05 | 2016-10-16 | 卡地拉保健有限公司 | 協同性組成物 |
IN2013MU02470A (cs) | 2013-07-25 | 2015-06-26 | Cadila Healthcare Ltd | |
WO2015033357A2 (en) | 2013-09-06 | 2015-03-12 | Cadila Healthcare Limited | An improved process for the preparation of pyrrole derivatives |
WO2017064635A2 (en) | 2015-10-14 | 2017-04-20 | Cadila Healthcare Limited | Pyrrole compound, compositions and process for preparation thereof |
US20180243263A1 (en) | 2016-12-09 | 2018-08-30 | Cadila Healthcare Ltd. | Treatment for primary biliary cholangitis |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5089514A (en) * | 1990-06-14 | 1992-02-18 | Pfizer Inc. | 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents |
PL174610B1 (pl) * | 1992-07-03 | 1998-08-31 | Smithkline Beecham Plc | Nowe związki heterocykliczne |
-
1995
- 1995-06-07 BR BR9508468A patent/BR9508468A/pt unknown
- 1995-06-07 WO PCT/GB1995/001323 patent/WO1996004261A1/en active Search and Examination
- 1995-07-26 DZ DZ950094A patent/DZ1916A1/fr active
- 1995-07-27 IL IL12552595A patent/IL125525A/xx unknown
- 1995-07-27 MA MA23972A patent/MA23632A1/fr unknown
- 1995-07-27 IL IL11475995A patent/IL114759A/xx unknown
- 1995-07-28 EP EP95930436A patent/EP0772605A1/en not_active Withdrawn
- 1995-07-28 MX MX9700763A patent/MX9700763A/es unknown
- 1995-07-28 WO PCT/EP1995/003038 patent/WO1996004260A1/en not_active Application Discontinuation
- 1995-07-28 AP APAP/P/1997/000918A patent/AP776A/en active
- 1995-07-28 CA CA002196079A patent/CA2196079A1/en not_active Abandoned
- 1995-07-28 PL PL95318766A patent/PL318766A1/xx unknown
- 1995-07-28 HU HU9700264A patent/HUT76637A/hu unknown
- 1995-07-28 SK SK122-97A patent/SK12297A3/sk unknown
- 1995-07-28 CZ CZ97254A patent/CZ25497A3/cs unknown
-
1997
- 1997-01-28 NO NO970373A patent/NO307827B1/no not_active IP Right Cessation
- 1997-01-28 FI FI970357A patent/FI970357A/fi unknown
- 1997-01-29 OA OA60957A patent/OA10470A/en unknown
-
1998
- 1998-07-27 IL IL12552598A patent/IL125525A0/xx unknown
Also Published As
Publication number | Publication date |
---|---|
AP776A (en) | 1999-10-28 |
IL125525A0 (en) | 1999-03-12 |
WO1996004260A1 (en) | 1996-02-15 |
OA10470A (en) | 2002-04-08 |
NO970373L (no) | 1997-03-18 |
NO307827B1 (no) | 2000-06-05 |
IL114759A (en) | 1999-10-28 |
IL114759A0 (en) | 1995-12-31 |
HUT76637A (en) | 1997-10-28 |
EP0772605A1 (en) | 1997-05-14 |
NO970373D0 (no) | 1997-01-28 |
AP9700918A0 (en) | 1997-01-31 |
FI970357A (fi) | 1997-03-26 |
CZ25497A3 (en) | 1997-09-17 |
WO1996004261A1 (en) | 1996-02-15 |
MA23632A1 (fr) | 1996-04-01 |
DZ1916A1 (fr) | 2002-02-17 |
IL125525A (en) | 2000-02-29 |
PL318766A1 (en) | 1997-07-07 |
MX9700763A (es) | 1997-05-31 |
FI970357A0 (fi) | 1997-01-28 |
CA2196079A1 (en) | 1996-02-15 |
BR9508468A (pt) | 1997-11-25 |
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