MX9700763A - Procedimiento para la preparacion de benzoxazoles y derivados de piridinas utiles en el tratamiento de la diabetes del tipo ii, los benzoxazoles y derivados de piridina obtenidos, composiciones de los mismos y su uso. - Google Patents
Procedimiento para la preparacion de benzoxazoles y derivados de piridinas utiles en el tratamiento de la diabetes del tipo ii, los benzoxazoles y derivados de piridina obtenidos, composiciones de los mismos y su uso.Info
- Publication number
- MX9700763A MX9700763A MX9700763A MX9700763A MX9700763A MX 9700763 A MX9700763 A MX 9700763A MX 9700763 A MX9700763 A MX 9700763A MX 9700763 A MX9700763 A MX 9700763A MX 9700763 A MX9700763 A MX 9700763A
- Authority
- MX
- Mexico
- Prior art keywords
- pryridine
- benzoxazoles
- diabetes
- treatment
- type
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
Un compuesto de la formula (I) o una sal farmacéuticamente aceptable del mismo, y/o un solvato farmacéuticamente aceptable del mismo, en donde R?? representa 2-benzoxazolilo o 2-piridilo y R1 representa CH2OCH3 o CF3; un procedimiento para la preparacion de dichos compuestos, una composicion farmacéutica que contiene dichos compuestos y el uso de dichos compuestos y composiciones en medicina.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9415330A GB9415330D0 (en) | 1994-07-29 | 1994-07-29 | Novel compounds |
GBGB9425599.9A GB9425599D0 (en) | 1994-12-19 | 1994-12-19 | Novel compounds |
GBGB9509923.0A GB9509923D0 (en) | 1995-05-17 | 1995-05-17 | Novel compounds |
PCT/GB1995/001323 WO1996004261A1 (en) | 1994-07-29 | 1995-06-07 | Benzoxazoles and pryridine derivatives useful in the treatment of the type ii diabetes |
PCT/EP1995/003038 WO1996004260A1 (en) | 1994-07-29 | 1995-07-28 | Benzoxazoles and pyridine derivatives useful in the treatment of the type ii diabetes |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9700763A true MX9700763A (es) | 1997-05-31 |
Family
ID=27267309
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9700763A MX9700763A (es) | 1994-07-29 | 1995-07-28 | Procedimiento para la preparacion de benzoxazoles y derivados de piridinas utiles en el tratamiento de la diabetes del tipo ii, los benzoxazoles y derivados de piridina obtenidos, composiciones de los mismos y su uso. |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0772605A1 (es) |
AP (1) | AP776A (es) |
BR (1) | BR9508468A (es) |
CA (1) | CA2196079A1 (es) |
CZ (1) | CZ25497A3 (es) |
DZ (1) | DZ1916A1 (es) |
FI (1) | FI970357A (es) |
HU (1) | HUT76637A (es) |
IL (3) | IL114759A (es) |
MA (1) | MA23632A1 (es) |
MX (1) | MX9700763A (es) |
NO (1) | NO307827B1 (es) |
OA (1) | OA10470A (es) |
PL (1) | PL318766A1 (es) |
SK (1) | SK12297A3 (es) |
WO (2) | WO1996004261A1 (es) |
Families Citing this family (64)
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GB9600464D0 (en) * | 1996-01-09 | 1996-03-13 | Smithkline Beecham Plc | Novel method |
CZ318098A3 (cs) * | 1996-04-04 | 1999-01-13 | Sankyo Company, Limited | Deriváty fenylalkylkarboxylové kyseliny, způsob jejich přípravy a farmaceutický prostředek, který je obsahuje |
US6090839A (en) * | 1996-12-23 | 2000-07-18 | Merck & Co., Inc. | Antidiabetic agents |
US6160000A (en) * | 1996-12-23 | 2000-12-12 | Merck & Co., Inc. | Antidiabetic agents based on aryl and heteroarylacetic acids |
CA2305808A1 (en) | 1997-10-02 | 1999-04-15 | Sankyo Company Limited | Amidocarboxylic acid derivatives |
WO1999019313A1 (en) * | 1997-10-27 | 1999-04-22 | Dr. Reddy's Research Foundation | Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them |
KR100517644B1 (ko) | 1997-10-27 | 2005-09-28 | 닥터 레디스 레보러터리즈 리미티드 | 신규의 삼원 화합물 및 그 약학적 용도, 그 제조방법 및이들을 포함하는 약제학적 조성물 |
US6440961B1 (en) | 1997-10-27 | 2002-08-27 | Dr. Reddy's Research Foundation | Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them |
US6369067B1 (en) | 1997-10-27 | 2002-04-09 | Dr. Reddy's Research Foundation | Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them |
US6265401B1 (en) * | 1997-10-27 | 2001-07-24 | Reddy-Cheminor, Inc. | Bicyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them |
EP1124807A1 (en) | 1997-10-27 | 2001-08-22 | Dr. Reddy's Research Foundation | Novel heterocyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them |
CA2307068C (en) | 1997-10-27 | 2007-04-10 | Dr. Reddy's Research Foundation | Bicyclic compounds, process for their preparation and pharmaceutical compositions containing them |
US6444816B1 (en) | 1997-10-27 | 2002-09-03 | Dr. Reddy's Research Foundation | Fused 7-oxo-pyrimidinyl compounds, preparation, composition and use thereof |
PL341795A1 (en) * | 1998-05-27 | 2001-05-07 | Reddy Research Foundation | Bicycle compounds, process for obtaining them and pharmacological compositions containing such compounds |
CN1319012A (zh) | 1998-09-17 | 2001-10-24 | 布里斯托尔-迈尔斯斯奎布公司 | 用aP2抑制剂及其联合形式治疗糖尿病的方法 |
WO2000023416A1 (en) * | 1998-10-21 | 2000-04-27 | Novo Nordisk A/S | New compounds, their preparation and use |
US6365586B1 (en) | 1998-10-21 | 2002-04-02 | Novo Nordisk A/S | Compounds, their preparation and use |
EP1123267A1 (en) | 1998-10-21 | 2001-08-16 | Novo Nordisk A/S | New compounds, their preparation and use |
EP1123269A1 (en) * | 1998-10-21 | 2001-08-16 | Novo Nordisk A/S | New compounds, their preparation and use |
JP2002527507A (ja) * | 1998-10-21 | 2002-08-27 | ノボ ノルディスク アクティーゼルスカブ | 新規化合物類、それらの調製及び使用 |
US6248781B1 (en) | 1998-10-21 | 2001-06-19 | Novo Nordisk A/S | Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR) |
EP1123292A1 (en) * | 1998-10-21 | 2001-08-16 | Novo Nordisk A/S | New compounds, their preparation and use |
US6468996B1 (en) | 1998-10-21 | 2002-10-22 | Novo Nordisk A/S | Substituted hetero-polycyclic compounds as PPARα and PPARγ activators |
US6214820B1 (en) | 1998-10-21 | 2001-04-10 | Novo Nordisk A/S | Compounds, their preparation and use |
WO2000023451A1 (en) * | 1998-10-21 | 2000-04-27 | Novo Nordisk A/S | New compounds, their preparation and use |
US6300339B1 (en) | 1998-10-21 | 2001-10-09 | Novo Nordisk A/S | Compounds, their preparation and use |
JP2002528535A (ja) | 1998-10-29 | 2002-09-03 | ドクター・レディーズ・リサーチ・ファウンデーション | 新規抗糖尿病剤製造の改良方法 |
US6531596B1 (en) | 1998-10-29 | 2003-03-11 | Dr. Reddy's Laboratories Ltd. | Process for the preparation of new antidiabetic agents |
WO2000063189A1 (en) * | 1999-04-16 | 2000-10-26 | Novo Nordisk A/S | Crystalline r- guanidines, arginine or (l) -arginine (2s) -2- ethoxy -3-{4- [2-(10h -phenoxazin -10-yl)ethoxy]phenyl}propanoate |
US6369055B1 (en) | 1999-04-20 | 2002-04-09 | Novo Nordisk A/S | Compounds, their preparation and use |
AU3958100A (en) | 1999-04-20 | 2000-11-02 | Novo Nordisk A/S | New compounds, their preparation and use |
US6972294B1 (en) | 1999-04-20 | 2005-12-06 | Novo Nordisk, A/S | Compounds, their preparation and use |
US6274608B1 (en) | 1999-04-20 | 2001-08-14 | Novo Nordisk A/S | Compounds, their preparation and use |
EP1171431A1 (en) * | 1999-04-20 | 2002-01-16 | Novo Nordisk A/S | Compounds, their preparation and use |
US7414128B2 (en) | 1999-04-20 | 2008-08-19 | Dr. Reddy's Laboratories, Limited | Crystalline R-guanidines, Arginine or (L)-Arginine (2S)-2-Ethoxy-3-{4-[2-(10H -phenoxazin-10-yl)ethoxy]phenyl}propanoate |
CN1348439A (zh) * | 1999-04-20 | 2002-05-08 | 诺沃挪第克公司 | 新化合物及其制备和用途 |
KR100610578B1 (ko) | 1999-04-28 | 2006-08-09 | 닥터 레디스 레보러터리즈 리미티드 | 치환된 이원 헤테로고리, 비만증 및 고콜레스테롤증치료제로서의 그 용도 |
DK1206457T3 (da) | 1999-08-27 | 2004-02-16 | Lilly Co Eli | Biaryl-oxa(thia)zolderivater og deres anvendelse som modulatorer PPAP'ER |
DK1250323T3 (da) * | 2000-01-19 | 2014-02-03 | Cadila Healthcare Ltd | Forbindelser med hypolipidemiske og hypokolesterolemiske virkninger, fremgangsmåde til deres fremstilling og farmaceutiske sammensætninger indeholdende dem |
US6555577B1 (en) | 2000-01-28 | 2003-04-29 | Novo Nordisk A/S | Compounds, their preparation and use |
KR20020090211A (ko) * | 2000-01-28 | 2002-11-30 | 노보 노르디스크 에이/에스 | 알키닐 치환된 프로피온산 유도체 및 당뇨병 및 비만에대한 그것의 사용 |
US6569901B2 (en) | 2000-01-28 | 2003-05-27 | Novo Nordisk A/S | Alkynyl-substituted propionic acid derivatives, their preparation and use |
US6509374B2 (en) | 2000-04-17 | 2003-01-21 | Novo Nordisk A/S | Compounds, their preparation and use |
US6908908B2 (en) | 2000-05-12 | 2005-06-21 | Ortho-Mcneil Pharmaceutical, Inc. | Biologically active 4H-benzo [1,4] oxazin-3-ones |
EP1280783A2 (en) * | 2000-05-12 | 2003-02-05 | Ortho-McNeil Pharmaceutical, Inc. | Methods of treatment using benzoxazinones as peroxisome proliferator activated receptor gamma modulators |
MY141659A (en) | 2000-05-12 | 2010-05-31 | Ortho Mcneil Pharm Inc | Biologically active 4h-benzo[1,4]oxazin-3-ones. |
EP1280782A2 (en) * | 2000-05-12 | 2003-02-05 | Ortho-McNeil Pharmaceutical, Inc. | Novel benzoxazinones as peroxisome proliferator activated receptor gamma modulators and method of treatment |
US6987123B2 (en) | 2001-07-26 | 2006-01-17 | Cadila Healthcare Limited | Heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine |
US6869967B2 (en) | 2001-07-30 | 2005-03-22 | Novo Nordisk A/S | Peroxisome proliferator-activated receptor (PPAR) active vinyl carboxylic acid derivatives |
US7067530B2 (en) | 2001-07-30 | 2006-06-27 | Novo Nordisk A/S | Compounds, their preparation and use |
US7220877B2 (en) | 2001-10-17 | 2007-05-22 | Novo Nordisk A/S | Compounds, their preparation and use |
EP1461069A2 (en) | 2001-12-29 | 2004-09-29 | Novo Nordisk A/S | Combined use of a glp-1 compound and another drug for treating dyslipidemia |
US7015345B2 (en) | 2002-02-21 | 2006-03-21 | Asahi Kasei Pharma Corporation | Propionic acid derivatives |
US7816385B2 (en) | 2002-12-20 | 2010-10-19 | High Point Pharmaceuticals, Llc | Dimeric dicarboxylic acid derivatives, their preparation and use |
US6653334B1 (en) | 2002-12-27 | 2003-11-25 | Kowa Co., Ltd. | Benzoxazole compound and pharmaceutical composition containing the same |
EP2154131A4 (en) * | 2007-04-26 | 2011-09-21 | Pharmafrontier Co Ltd | INHIBITOR OF THE G-PROTEIN-COUPLED RECEPTOR AND PHARMACEUTICAL PRODUCT |
ES2569248T3 (es) | 2011-01-31 | 2016-05-09 | Cadila Healthcare Limited | Tratamiento para la lipodistrofia |
MX346943B (es) | 2013-04-22 | 2017-04-06 | Cadila Healthcare Ltd | Una nueva composición para esteatosis hepática no alcohólica (nafld). |
ES2889916T3 (es) | 2013-05-30 | 2022-01-14 | Cadila Healthcare Ltd | Un procedimiento para la preparación de pirroles con actividades hipolipidémicas e hipocolesterémicas |
TW201636015A (zh) | 2013-07-05 | 2016-10-16 | 卡地拉保健有限公司 | 協同性組成物 |
IN2013MU02470A (es) | 2013-07-25 | 2015-06-26 | Cadila Healthcare Ltd | |
IN2013MU02905A (es) | 2013-09-06 | 2015-07-03 | Cadila Healthcare Ltd | |
WO2017064635A2 (en) | 2015-10-14 | 2017-04-20 | Cadila Healthcare Limited | Pyrrole compound, compositions and process for preparation thereof |
JP6840853B2 (ja) | 2016-12-09 | 2021-03-10 | カディラ・ヘルスケア・リミテッド | 原発性胆汁性胆管炎の治療 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5089514A (en) * | 1990-06-14 | 1992-02-18 | Pfizer Inc. | 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents |
DE69331010D1 (de) * | 1992-07-03 | 2001-11-29 | Smithkline Beecham Plc | Benzoxazol- und benzothiazol-derivate als arzneimittel |
-
1995
- 1995-06-07 BR BR9508468A patent/BR9508468A/pt unknown
- 1995-06-07 WO PCT/GB1995/001323 patent/WO1996004261A1/en active Search and Examination
- 1995-07-26 DZ DZ950094A patent/DZ1916A1/fr active
- 1995-07-27 IL IL11475995A patent/IL114759A/xx unknown
- 1995-07-27 MA MA23972A patent/MA23632A1/fr unknown
- 1995-07-27 IL IL12552595A patent/IL125525A/xx unknown
- 1995-07-28 WO PCT/EP1995/003038 patent/WO1996004260A1/en not_active Application Discontinuation
- 1995-07-28 AP APAP/P/1997/000918A patent/AP776A/en active
- 1995-07-28 HU HU9700264A patent/HUT76637A/hu unknown
- 1995-07-28 MX MX9700763A patent/MX9700763A/es unknown
- 1995-07-28 EP EP95930436A patent/EP0772605A1/en not_active Withdrawn
- 1995-07-28 SK SK122-97A patent/SK12297A3/sk unknown
- 1995-07-28 CA CA002196079A patent/CA2196079A1/en not_active Abandoned
- 1995-07-28 PL PL95318766A patent/PL318766A1/xx unknown
- 1995-07-28 CZ CZ97254A patent/CZ25497A3/cs unknown
-
1997
- 1997-01-28 NO NO970373A patent/NO307827B1/no not_active IP Right Cessation
- 1997-01-28 FI FI970357A patent/FI970357A/fi unknown
- 1997-01-29 OA OA60957A patent/OA10470A/en unknown
-
1998
- 1998-07-27 IL IL12552598A patent/IL125525A0/xx unknown
Also Published As
Publication number | Publication date |
---|---|
CA2196079A1 (en) | 1996-02-15 |
NO970373L (no) | 1997-03-18 |
WO1996004260A1 (en) | 1996-02-15 |
IL114759A0 (en) | 1995-12-31 |
MA23632A1 (fr) | 1996-04-01 |
WO1996004261A1 (en) | 1996-02-15 |
IL125525A0 (en) | 1999-03-12 |
PL318766A1 (en) | 1997-07-07 |
EP0772605A1 (en) | 1997-05-14 |
IL125525A (en) | 2000-02-29 |
NO307827B1 (no) | 2000-06-05 |
FI970357A0 (fi) | 1997-01-28 |
HUT76637A (en) | 1997-10-28 |
DZ1916A1 (fr) | 2002-02-17 |
IL114759A (en) | 1999-10-28 |
BR9508468A (pt) | 1997-11-25 |
AP776A (en) | 1999-10-28 |
NO970373D0 (no) | 1997-01-28 |
SK12297A3 (en) | 1997-08-06 |
FI970357A (fi) | 1997-03-26 |
OA10470A (en) | 2002-04-08 |
AP9700918A0 (en) | 1997-01-31 |
CZ25497A3 (en) | 1997-09-17 |
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