FI970357A0 - Tyypin II diabeteksen hoitoon käyttökelpoisia bensoksatsoli- ja pyridiinijohdannaisia - Google Patents
Tyypin II diabeteksen hoitoon käyttökelpoisia bensoksatsoli- ja pyridiinijohdannaisiaInfo
- Publication number
- FI970357A0 FI970357A0 FI970357A FI970357A FI970357A0 FI 970357 A0 FI970357 A0 FI 970357A0 FI 970357 A FI970357 A FI 970357A FI 970357 A FI970357 A FI 970357A FI 970357 A0 FI970357 A0 FI 970357A0
- Authority
- FI
- Finland
- Prior art keywords
- benzoxazole
- diabetes
- treatment
- type
- pyridine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9415330A GB9415330D0 (en) | 1994-07-29 | 1994-07-29 | Novel compounds |
GBGB9425599.9A GB9425599D0 (en) | 1994-12-19 | 1994-12-19 | Novel compounds |
GBGB9509923.0A GB9509923D0 (en) | 1995-05-17 | 1995-05-17 | Novel compounds |
PCT/GB1995/001323 WO1996004261A1 (en) | 1994-07-29 | 1995-06-07 | Benzoxazoles and pryridine derivatives useful in the treatment of the type ii diabetes |
PCT/EP1995/003038 WO1996004260A1 (en) | 1994-07-29 | 1995-07-28 | Benzoxazoles and pyridine derivatives useful in the treatment of the type ii diabetes |
Publications (2)
Publication Number | Publication Date |
---|---|
FI970357A0 true FI970357A0 (fi) | 1997-01-28 |
FI970357A FI970357A (fi) | 1997-03-26 |
Family
ID=27267309
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI970357A FI970357A (fi) | 1994-07-29 | 1997-01-28 | Tyypin II diabeteksen hoitoon käyttökelpoisia bensoksatsoli- ja pyridiinijohdannaisia |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0772605A1 (fi) |
AP (1) | AP776A (fi) |
BR (1) | BR9508468A (fi) |
CA (1) | CA2196079A1 (fi) |
CZ (1) | CZ25497A3 (fi) |
DZ (1) | DZ1916A1 (fi) |
FI (1) | FI970357A (fi) |
HU (1) | HUT76637A (fi) |
IL (3) | IL114759A (fi) |
MA (1) | MA23632A1 (fi) |
MX (1) | MX9700763A (fi) |
NO (1) | NO307827B1 (fi) |
OA (1) | OA10470A (fi) |
PL (1) | PL318766A1 (fi) |
SK (1) | SK12297A3 (fi) |
WO (2) | WO1996004261A1 (fi) |
Families Citing this family (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9600464D0 (en) * | 1996-01-09 | 1996-03-13 | Smithkline Beecham Plc | Novel method |
DE69725585T2 (de) * | 1996-04-04 | 2004-07-01 | Sankyo Co., Ltd. | Phenylalkylcarbonsäure-derivate |
US6090839A (en) * | 1996-12-23 | 2000-07-18 | Merck & Co., Inc. | Antidiabetic agents |
US6160000A (en) * | 1996-12-23 | 2000-12-12 | Merck & Co., Inc. | Antidiabetic agents based on aryl and heteroarylacetic acids |
PL339660A1 (en) | 1997-10-02 | 2001-01-02 | Sankyo Co | Derivatives of amidocarboxylic acids |
US6440961B1 (en) | 1997-10-27 | 2002-08-27 | Dr. Reddy's Research Foundation | Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them |
US6265401B1 (en) | 1997-10-27 | 2001-07-24 | Reddy-Cheminor, Inc. | Bicyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them |
US6369067B1 (en) | 1997-10-27 | 2002-04-09 | Dr. Reddy's Research Foundation | Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them |
BR9812770A (pt) | 1997-10-27 | 2000-12-12 | Reddy Research Foundation | Compostos bicìclicos, processo para seu preparo e composições farmacêuticas contendo os mesmos |
CN1280574A (zh) | 1997-10-27 | 2001-01-17 | 雷迪研究基金会 | 新的杂环化合物及其在医药中的应用、它们的制备方法和含有它们的药物组合物 |
MXPA00004036A (es) * | 1997-10-27 | 2006-05-24 | Reddys Lab Ltd Dr | Compuestos triciclicos novedosos y su uso en medicina; proceso para su preparacion y composiciones farmaceuticas que los contienen.. |
WO1999019313A1 (en) * | 1997-10-27 | 1999-04-22 | Dr. Reddy's Research Foundation | Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them |
US6444816B1 (en) | 1997-10-27 | 2002-09-03 | Dr. Reddy's Research Foundation | Fused 7-oxo-pyrimidinyl compounds, preparation, composition and use thereof |
NZ504106A (en) * | 1998-05-27 | 2003-02-28 | Dr | Fused Oxazine, Thiazine and pipyridine compounds, process for their preparation and pharmaceutical compositions containing them |
TR200100773T2 (tr) | 1998-09-17 | 2001-07-23 | Bristol-Myers Squibb Company | Bir aP2 önleyicisinin ve kombinasyonunun kullanıldığı diyabet tedavi yöntemi |
US6214820B1 (en) | 1998-10-21 | 2001-04-10 | Novo Nordisk A/S | Compounds, their preparation and use |
JP2002527516A (ja) * | 1998-10-21 | 2002-08-27 | ノボ ノルディスク アクティーゼルスカブ | 新規化合物、それらの製造及び使用 |
WO2000023415A1 (en) * | 1998-10-21 | 2000-04-27 | Novo Nordisk A/S | New compounds, their preparation and use |
JP2002527503A (ja) * | 1998-10-21 | 2002-08-27 | ノボ ノルディスク アクティーゼルスカブ | 新規化合物類、それらの調製及び使用 |
US6365586B1 (en) | 1998-10-21 | 2002-04-02 | Novo Nordisk A/S | Compounds, their preparation and use |
US6300339B1 (en) | 1998-10-21 | 2001-10-09 | Novo Nordisk A/S | Compounds, their preparation and use |
EP1123279A1 (en) * | 1998-10-21 | 2001-08-16 | Novo Nordisk A/S | New compounds, their preparation and use |
WO2000023416A1 (en) * | 1998-10-21 | 2000-04-27 | Novo Nordisk A/S | New compounds, their preparation and use |
US6468996B1 (en) | 1998-10-21 | 2002-10-22 | Novo Nordisk A/S | Substituted hetero-polycyclic compounds as PPARα and PPARγ activators |
US6248781B1 (en) | 1998-10-21 | 2001-06-19 | Novo Nordisk A/S | Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR) |
JP2002527520A (ja) * | 1998-10-21 | 2002-08-27 | ノボ ノルディスク アクティーゼルスカブ | 新規化合物、その製造及び使用 |
UA60386C2 (uk) | 1998-10-29 | 2003-10-15 | Reddys Laboratories Ltd | Спосіб одержання похідних 3-[4-[2-(феноксазин-10-іл)метокси]феніл]пропіонової кислоти (варіанти) та проміжні сполуки для їх отримання |
US6531596B1 (en) | 1998-10-29 | 2003-03-11 | Dr. Reddy's Laboratories Ltd. | Process for the preparation of new antidiabetic agents |
AU4465200A (en) * | 1999-04-16 | 2000-11-02 | Dr. Reddy's Research Foundation | Novel polymorphic forms of an antidiabetic agent: process for their preparation and a pharmaceutical composition containing them |
US6369055B1 (en) | 1999-04-20 | 2002-04-09 | Novo Nordisk A/S | Compounds, their preparation and use |
JP2002542218A (ja) * | 1999-04-20 | 2002-12-10 | ノボ ノルディスク アクティーゼルスカブ | 新規な化合物、それらの製造および使用 |
US6972294B1 (en) | 1999-04-20 | 2005-12-06 | Novo Nordisk, A/S | Compounds, their preparation and use |
EP1171438A1 (en) | 1999-04-20 | 2002-01-16 | Novo Nordisk A/S | Compounds, their preparation and use |
US7414128B2 (en) | 1999-04-20 | 2008-08-19 | Dr. Reddy's Laboratories, Limited | Crystalline R-guanidines, Arginine or (L)-Arginine (2S)-2-Ethoxy-3-{4-[2-(10H -phenoxazin-10-yl)ethoxy]phenyl}propanoate |
US6274608B1 (en) | 1999-04-20 | 2001-08-14 | Novo Nordisk A/S | Compounds, their preparation and use |
WO2000063190A1 (en) * | 1999-04-20 | 2000-10-26 | Novo Nordisk A/S | New compounds, their preparation and use |
SK15092001A3 (sk) * | 1999-04-28 | 2002-05-09 | Dr. Reddy's Research Foundation | Substituované bicyklické heterocyklické zlúčeniny, spôsob ich prípravy a ich použitie ako antiobezitných a hypocholesterolemických činidiel |
PT1206457E (pt) | 1999-08-27 | 2004-03-31 | Lilly Co Eli | Derivados de diaril-oxa(tia)zol e seu uso como moduladores dos ppars |
BRPI0108024B8 (pt) * | 2000-01-19 | 2021-05-25 | Cadila Healthcare Ltd | composto, processo para a preparação de um composto, composição farmacêutica, uso do composto, novo intermediário e processo para a preparação de um novo intermediário |
US6555577B1 (en) | 2000-01-28 | 2003-04-29 | Novo Nordisk A/S | Compounds, their preparation and use |
US6569901B2 (en) | 2000-01-28 | 2003-05-27 | Novo Nordisk A/S | Alkynyl-substituted propionic acid derivatives, their preparation and use |
CN1396904A (zh) * | 2000-01-28 | 2003-02-12 | 诺沃挪第克公司 | 新颖的化合物、它们的制备和用途 |
US6509374B2 (en) | 2000-04-17 | 2003-01-21 | Novo Nordisk A/S | Compounds, their preparation and use |
AU2001261503A1 (en) * | 2000-05-12 | 2001-11-26 | Ortho-Mcneil Pharmaceutical, Inc. | Methods of treatment using benzoxazinones as peroxisome proliferator activated receptor gamma modulators |
US6908908B2 (en) | 2000-05-12 | 2005-06-21 | Ortho-Mcneil Pharmaceutical, Inc. | Biologically active 4H-benzo [1,4] oxazin-3-ones |
US6599899B2 (en) | 2000-05-12 | 2003-07-29 | Ortho-Mcneil Pharmaceutical, Inc. | Benzoxazinones as peroxisome proliferator activated receptor gamma modulators and method of treatment |
ES2288957T3 (es) * | 2000-05-12 | 2008-02-01 | Ortho-Mcneil Pharmaceutical, Inc. | 4h-benzo(1.4)oxazin-3-ina biologicamente activas. |
US6987123B2 (en) | 2001-07-26 | 2006-01-17 | Cadila Healthcare Limited | Heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine |
US7067530B2 (en) | 2001-07-30 | 2006-06-27 | Novo Nordisk A/S | Compounds, their preparation and use |
US6869967B2 (en) | 2001-07-30 | 2005-03-22 | Novo Nordisk A/S | Peroxisome proliferator-activated receptor (PPAR) active vinyl carboxylic acid derivatives |
US7220877B2 (en) | 2001-10-17 | 2007-05-22 | Novo Nordisk A/S | Compounds, their preparation and use |
JP2005518408A (ja) | 2001-12-29 | 2005-06-23 | ノボ ノルディスク アクティーゼルスカブ | 異常脂肪血症を治療するための、glp−1化合物と他の薬物との組み合わせ使用 |
US7015345B2 (en) | 2002-02-21 | 2006-03-21 | Asahi Kasei Pharma Corporation | Propionic acid derivatives |
US7816385B2 (en) | 2002-12-20 | 2010-10-19 | High Point Pharmaceuticals, Llc | Dimeric dicarboxylic acid derivatives, their preparation and use |
US6653334B1 (en) | 2002-12-27 | 2003-11-25 | Kowa Co., Ltd. | Benzoxazole compound and pharmaceutical composition containing the same |
JPWO2008139879A1 (ja) * | 2007-04-26 | 2010-07-29 | ファルマフロンティア株式会社 | G蛋白質共役型レセプター抑制剤および医薬 |
BR112013019352A2 (pt) | 2011-01-31 | 2020-07-14 | Cadila Healthcare Limited | método para o tratamento de lipodistrofia, uso de um composto, dosagem diária, método de tratamento, composição farmacêutica, uso da composição farmacêutica e composto |
WO2014174524A1 (en) | 2013-04-22 | 2014-10-30 | Cadila Healthcare Limited | A novel composition for nonalcoholic fatty liver disease (nafld) |
ES2889916T3 (es) | 2013-05-30 | 2022-01-14 | Cadila Healthcare Ltd | Un procedimiento para la preparación de pirroles con actividades hipolipidémicas e hipocolesterémicas |
TW201513857A (zh) | 2013-07-05 | 2015-04-16 | Cadila Healthcare Ltd | 協同性組成物 |
IN2013MU02470A (fi) | 2013-07-25 | 2015-06-26 | Cadila Healthcare Ltd | |
IN2013MU02905A (fi) | 2013-09-06 | 2015-07-03 | Cadila Healthcare Ltd | |
WO2017064635A2 (en) | 2015-10-14 | 2017-04-20 | Cadila Healthcare Limited | Pyrrole compound, compositions and process for preparation thereof |
WO2018104916A1 (en) | 2016-12-09 | 2018-06-14 | Cadila Healthcare Limited | Treatment for primary biliary cholangitis |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5089514A (en) * | 1990-06-14 | 1992-02-18 | Pfizer Inc. | 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents |
WO1994001420A1 (en) * | 1992-07-03 | 1994-01-20 | Smithkline Beecham Plc | Heterocyclic compounds as pharmaceutical |
-
1995
- 1995-06-07 BR BR9508468A patent/BR9508468A/pt unknown
- 1995-06-07 WO PCT/GB1995/001323 patent/WO1996004261A1/en active Search and Examination
- 1995-07-26 DZ DZ950094A patent/DZ1916A1/fr active
- 1995-07-27 MA MA23972A patent/MA23632A1/fr unknown
- 1995-07-27 IL IL11475995A patent/IL114759A/xx unknown
- 1995-07-27 IL IL12552595A patent/IL125525A/xx unknown
- 1995-07-28 EP EP95930436A patent/EP0772605A1/en not_active Withdrawn
- 1995-07-28 CA CA002196079A patent/CA2196079A1/en not_active Abandoned
- 1995-07-28 PL PL95318766A patent/PL318766A1/xx unknown
- 1995-07-28 AP APAP/P/1997/000918A patent/AP776A/en active
- 1995-07-28 SK SK122-97A patent/SK12297A3/sk unknown
- 1995-07-28 CZ CZ97254A patent/CZ25497A3/cs unknown
- 1995-07-28 HU HU9700264A patent/HUT76637A/hu unknown
- 1995-07-28 MX MX9700763A patent/MX9700763A/es unknown
- 1995-07-28 WO PCT/EP1995/003038 patent/WO1996004260A1/en not_active Application Discontinuation
-
1997
- 1997-01-28 NO NO970373A patent/NO307827B1/no not_active IP Right Cessation
- 1997-01-28 FI FI970357A patent/FI970357A/fi unknown
- 1997-01-29 OA OA60957A patent/OA10470A/en unknown
-
1998
- 1998-07-27 IL IL12552598A patent/IL125525A0/xx unknown
Also Published As
Publication number | Publication date |
---|---|
IL114759A0 (en) | 1995-12-31 |
CZ25497A3 (en) | 1997-09-17 |
HUT76637A (en) | 1997-10-28 |
MX9700763A (es) | 1997-05-31 |
FI970357A (fi) | 1997-03-26 |
AP9700918A0 (en) | 1997-01-31 |
SK12297A3 (en) | 1997-08-06 |
NO970373L (no) | 1997-03-18 |
CA2196079A1 (en) | 1996-02-15 |
OA10470A (en) | 2002-04-08 |
WO1996004260A1 (en) | 1996-02-15 |
EP0772605A1 (en) | 1997-05-14 |
IL114759A (en) | 1999-10-28 |
NO307827B1 (no) | 2000-06-05 |
MA23632A1 (fr) | 1996-04-01 |
IL125525A (en) | 2000-02-29 |
WO1996004261A1 (en) | 1996-02-15 |
IL125525A0 (en) | 1999-03-12 |
NO970373D0 (no) | 1997-01-28 |
BR9508468A (pt) | 1997-11-25 |
AP776A (en) | 1999-10-28 |
PL318766A1 (en) | 1997-07-07 |
DZ1916A1 (fr) | 2002-02-17 |
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