IL114759A - Benzoxazole derivatives and pharmaceutical compositions containing them - Google Patents
Benzoxazole derivatives and pharmaceutical compositions containing themInfo
- Publication number
- IL114759A IL114759A IL11475995A IL11475995A IL114759A IL 114759 A IL114759 A IL 114759A IL 11475995 A IL11475995 A IL 11475995A IL 11475995 A IL11475995 A IL 11475995A IL 114759 A IL114759 A IL 114759A
- Authority
- IL
- Israel
- Prior art keywords
- pharmaceutical compositions
- compositions containing
- benzoxazole derivatives
- benzoxazole
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL12552595A IL125525A (en) | 1994-07-29 | 1995-07-27 | Hydroxyalkylamine derivatives |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9415330A GB9415330D0 (en) | 1994-07-29 | 1994-07-29 | Novel compounds |
GBGB9425599.9A GB9425599D0 (en) | 1994-12-19 | 1994-12-19 | Novel compounds |
GBGB9509923.0A GB9509923D0 (en) | 1995-05-17 | 1995-05-17 | Novel compounds |
PCT/GB1995/001323 WO1996004261A1 (en) | 1994-07-29 | 1995-06-07 | Benzoxazoles and pryridine derivatives useful in the treatment of the type ii diabetes |
Publications (2)
Publication Number | Publication Date |
---|---|
IL114759A0 IL114759A0 (en) | 1995-12-31 |
IL114759A true IL114759A (en) | 1999-10-28 |
Family
ID=27267309
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL11475995A IL114759A (en) | 1994-07-29 | 1995-07-27 | Benzoxazole derivatives and pharmaceutical compositions containing them |
IL12552595A IL125525A (en) | 1994-07-29 | 1995-07-27 | Hydroxyalkylamine derivatives |
IL12552598A IL125525A0 (en) | 1994-07-29 | 1998-07-27 | Hydroxyalkylamine derivatives |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL12552595A IL125525A (en) | 1994-07-29 | 1995-07-27 | Hydroxyalkylamine derivatives |
IL12552598A IL125525A0 (en) | 1994-07-29 | 1998-07-27 | Hydroxyalkylamine derivatives |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0772605A1 (en) |
AP (1) | AP776A (en) |
BR (1) | BR9508468A (en) |
CA (1) | CA2196079A1 (en) |
CZ (1) | CZ25497A3 (en) |
DZ (1) | DZ1916A1 (en) |
FI (1) | FI970357A (en) |
HU (1) | HUT76637A (en) |
IL (3) | IL114759A (en) |
MA (1) | MA23632A1 (en) |
MX (1) | MX9700763A (en) |
NO (1) | NO307827B1 (en) |
OA (1) | OA10470A (en) |
PL (1) | PL318766A1 (en) |
SK (1) | SK12297A3 (en) |
WO (2) | WO1996004261A1 (en) |
Families Citing this family (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9600464D0 (en) * | 1996-01-09 | 1996-03-13 | Smithkline Beecham Plc | Novel method |
NZ332136A (en) * | 1996-04-04 | 1999-08-30 | Sankyo Co | Phenylalkylcarboxylic acid derivatives useful for treating hyperglycemia |
US6160000A (en) * | 1996-12-23 | 2000-12-12 | Merck & Co., Inc. | Antidiabetic agents based on aryl and heteroarylacetic acids |
US6090839A (en) * | 1996-12-23 | 2000-07-18 | Merck & Co., Inc. | Antidiabetic agents |
HUP0003881A3 (en) | 1997-10-02 | 2001-04-28 | Sankyo Co | Amidocarboxylic acid derivatives |
US6440961B1 (en) | 1997-10-27 | 2002-08-27 | Dr. Reddy's Research Foundation | Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them |
US6265401B1 (en) | 1997-10-27 | 2001-07-24 | Reddy-Cheminor, Inc. | Bicyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them |
CN100376560C (en) | 1997-10-27 | 2008-03-26 | 雷迪实验室有限公司 | New tricyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them |
RU2247722C2 (en) | 1997-10-27 | 2005-03-10 | Др. Редди`З Лабораториз Лимитед | Derivatives of aryl carboxylic acids, methods for their preparing, pharmaceutical composition based on thereof, methods for treatment and prophylaxis of different diseases, intermediate compounds and methods for their preparing |
WO1999019313A1 (en) * | 1997-10-27 | 1999-04-22 | Dr. Reddy's Research Foundation | Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them |
WO1999020614A1 (en) * | 1998-05-27 | 1999-04-29 | Dr. Reddy's Research Foundation | Bicyclic compounds, process for their preparation and pharmaceutical compositions containing them |
CN1280574A (en) | 1997-10-27 | 2001-01-17 | 雷迪研究基金会 | New heterocyclic compounds and their use in medicine, process for their prepartion and pharmaceutical compositions containing them |
US6369067B1 (en) | 1997-10-27 | 2002-04-09 | Dr. Reddy's Research Foundation | Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them |
US6444816B1 (en) | 1997-10-27 | 2002-09-03 | Dr. Reddy's Research Foundation | Fused 7-oxo-pyrimidinyl compounds, preparation, composition and use thereof |
PL346660A1 (en) | 1998-09-17 | 2002-02-25 | Bristol Myers Squibb Co | Method for treating atherosclerosis employing an ap2 inhibitor and combination |
US6300339B1 (en) | 1998-10-21 | 2001-10-09 | Novo Nordisk A/S | Compounds, their preparation and use |
US6365586B1 (en) | 1998-10-21 | 2002-04-02 | Novo Nordisk A/S | Compounds, their preparation and use |
JP2002527502A (en) * | 1998-10-21 | 2002-08-27 | ノボ ノルディスク アクティーゼルスカブ | New compounds, their preparation and use |
US6248781B1 (en) | 1998-10-21 | 2001-06-19 | Novo Nordisk A/S | Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR) |
US6468996B1 (en) | 1998-10-21 | 2002-10-22 | Novo Nordisk A/S | Substituted hetero-polycyclic compounds as PPARα and PPARγ activators |
EP1123297A1 (en) * | 1998-10-21 | 2001-08-16 | Novo Nordisk A/S | New compounds, their preparation and use |
AU6190199A (en) * | 1998-10-21 | 2000-05-08 | Dr. Reddy's Research Foundation | New compounds, their preparation and use |
WO2000023445A1 (en) * | 1998-10-21 | 2000-04-27 | Novo Nordisk A/S | New compounds, their preparation and use |
EP1123269A1 (en) * | 1998-10-21 | 2001-08-16 | Novo Nordisk A/S | New compounds, their preparation and use |
US6214820B1 (en) | 1998-10-21 | 2001-04-10 | Novo Nordisk A/S | Compounds, their preparation and use |
WO2000023425A1 (en) * | 1998-10-21 | 2000-04-27 | Novo Nordisk A/S | New compounds, their preparation and use |
US6531596B1 (en) | 1998-10-29 | 2003-03-11 | Dr. Reddy's Laboratories Ltd. | Process for the preparation of new antidiabetic agents |
BR9914438A (en) | 1998-10-29 | 2001-06-26 | Reddy Research Foundation | Improved process for preparing new anti-diabetic agents |
WO2000063189A1 (en) * | 1999-04-16 | 2000-10-26 | Novo Nordisk A/S | Crystalline r- guanidines, arginine or (l) -arginine (2s) -2- ethoxy -3-{4- [2-(10h -phenoxazin -10-yl)ethoxy]phenyl}propanoate |
US6369055B1 (en) | 1999-04-20 | 2002-04-09 | Novo Nordisk A/S | Compounds, their preparation and use |
US6274608B1 (en) | 1999-04-20 | 2001-08-14 | Novo Nordisk A/S | Compounds, their preparation and use |
CN1348439A (en) * | 1999-04-20 | 2002-05-08 | 诺沃挪第克公司 | New compounds, their preparation and use |
US6972294B1 (en) | 1999-04-20 | 2005-12-06 | Novo Nordisk, A/S | Compounds, their preparation and use |
WO2000063209A1 (en) * | 1999-04-20 | 2000-10-26 | Novo Nordisk A/S | New compounds, their preparation and use |
WO2000063190A1 (en) * | 1999-04-20 | 2000-10-26 | Novo Nordisk A/S | New compounds, their preparation and use |
US7414128B2 (en) | 1999-04-20 | 2008-08-19 | Dr. Reddy's Laboratories, Limited | Crystalline R-guanidines, Arginine or (L)-Arginine (2S)-2-Ethoxy-3-{4-[2-(10H -phenoxazin-10-yl)ethoxy]phenyl}propanoate |
JP2002543194A (en) * | 1999-04-28 | 2002-12-17 | ドクター・レディーズ・ラボラトリーズ・リミテッド | Substituted bicyclic heterocyclic compounds, processes for their preparation and their use as antiobesity and antihypercholesterolemia agents |
CA2382966A1 (en) | 1999-08-27 | 2001-03-08 | Eli Lilly And Company | Biaryl-oxa(thia)zole derivatives and their use as ppars modulators |
MEP32408A (en) * | 2000-01-19 | 2010-10-10 | Cadila Healthcare Ltd | Compounds having hypolipedemic and hypocholesteremic activities, process for their preparation and pharmaceutical compositions containing them |
US6555577B1 (en) | 2000-01-28 | 2003-04-29 | Novo Nordisk A/S | Compounds, their preparation and use |
US6569901B2 (en) | 2000-01-28 | 2003-05-27 | Novo Nordisk A/S | Alkynyl-substituted propionic acid derivatives, their preparation and use |
WO2001055086A1 (en) * | 2000-01-28 | 2001-08-02 | Novo Nordisk A/S | Alkynylsubstituted propionic acid derivatives and their use against diabetes and obesity |
US6509374B2 (en) | 2000-04-17 | 2003-01-21 | Novo Nordisk A/S | Compounds, their preparation and use |
WO2001087860A2 (en) * | 2000-05-12 | 2001-11-22 | Ortho-Mcneil Pharmaceutical, Inc. | Novel benzoxazinones as peroxisome proliferator activated receptor gamma modulators and method of treatment |
AU2001261503A1 (en) * | 2000-05-12 | 2001-11-26 | Ortho-Mcneil Pharmaceutical, Inc. | Methods of treatment using benzoxazinones as peroxisome proliferator activated receptor gamma modulators |
US6908908B2 (en) | 2000-05-12 | 2005-06-21 | Ortho-Mcneil Pharmaceutical, Inc. | Biologically active 4H-benzo [1,4] oxazin-3-ones |
ES2288957T3 (en) * | 2000-05-12 | 2008-02-01 | Ortho-Mcneil Pharmaceutical, Inc. | 4H-BENZO (1.4) OXAZIN-3-INA BIOLOGICALLY ACTIVE. |
US6987123B2 (en) | 2001-07-26 | 2006-01-17 | Cadila Healthcare Limited | Heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine |
US6869967B2 (en) | 2001-07-30 | 2005-03-22 | Novo Nordisk A/S | Peroxisome proliferator-activated receptor (PPAR) active vinyl carboxylic acid derivatives |
US7067530B2 (en) | 2001-07-30 | 2006-06-27 | Novo Nordisk A/S | Compounds, their preparation and use |
US7220877B2 (en) | 2001-10-17 | 2007-05-22 | Novo Nordisk A/S | Compounds, their preparation and use |
JP2005518408A (en) | 2001-12-29 | 2005-06-23 | ノボ ノルディスク アクティーゼルスカブ | Combination use of GLP-1 compounds and other drugs to treat dyslipidemia |
US7015345B2 (en) | 2002-02-21 | 2006-03-21 | Asahi Kasei Pharma Corporation | Propionic acid derivatives |
US7816385B2 (en) | 2002-12-20 | 2010-10-19 | High Point Pharmaceuticals, Llc | Dimeric dicarboxylic acid derivatives, their preparation and use |
US6653334B1 (en) | 2002-12-27 | 2003-11-25 | Kowa Co., Ltd. | Benzoxazole compound and pharmaceutical composition containing the same |
US20100274022A1 (en) * | 2007-04-26 | 2010-10-28 | Pharmafrontier Co., Ltd. | G protein-coupled receptor inhibitor and pharmaceutical product |
MX350611B (en) | 2011-01-31 | 2017-09-11 | Cadila Healthcare Ltd | Treatment for lipodystrophy. |
AU2013387996B2 (en) | 2013-04-22 | 2015-12-10 | Cadila Healthcare Limited | A novel composition for nonalcoholic fatty liver disease (NAFLD) |
MX2015016403A (en) | 2013-05-30 | 2016-04-11 | Cadila Healthcare Ltd | A process for preparation of pyrroles having hypolipidemic hypocholesteremic activities. |
TW201636015A (en) | 2013-07-05 | 2016-10-16 | 卡地拉保健有限公司 | Synergistic compositions |
IN2013MU02470A (en) | 2013-07-25 | 2015-06-26 | Cadila Healthcare Ltd | |
US10112898B2 (en) | 2013-09-06 | 2018-10-30 | Cadila Healthcare Limited | Process for the preparation of saroglitazar pharmaceutical salts |
WO2017064635A2 (en) | 2015-10-14 | 2017-04-20 | Cadila Healthcare Limited | Pyrrole compound, compositions and process for preparation thereof |
ES2894261T3 (en) | 2016-12-09 | 2022-02-14 | Cadila Healthcare Ltd | Treatment of primary biliary cholangitis |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5089514A (en) * | 1990-06-14 | 1992-02-18 | Pfizer Inc. | 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents |
PL174610B1 (en) * | 1992-07-03 | 1998-08-31 | Smithkline Beecham Plc | Novel heterocyclic compounds for use as pharmaceuticals |
-
1995
- 1995-06-07 BR BR9508468A patent/BR9508468A/en unknown
- 1995-06-07 WO PCT/GB1995/001323 patent/WO1996004261A1/en active Search and Examination
- 1995-07-26 DZ DZ950094A patent/DZ1916A1/en active
- 1995-07-27 MA MA23972A patent/MA23632A1/en unknown
- 1995-07-27 IL IL11475995A patent/IL114759A/en unknown
- 1995-07-27 IL IL12552595A patent/IL125525A/en unknown
- 1995-07-28 CZ CZ97254A patent/CZ25497A3/en unknown
- 1995-07-28 WO PCT/EP1995/003038 patent/WO1996004260A1/en not_active Application Discontinuation
- 1995-07-28 HU HU9700264A patent/HUT76637A/en unknown
- 1995-07-28 MX MX9700763A patent/MX9700763A/en unknown
- 1995-07-28 EP EP95930436A patent/EP0772605A1/en not_active Withdrawn
- 1995-07-28 PL PL95318766A patent/PL318766A1/en unknown
- 1995-07-28 AP APAP/P/1997/000918A patent/AP776A/en active
- 1995-07-28 CA CA002196079A patent/CA2196079A1/en not_active Abandoned
- 1995-07-28 SK SK122-97A patent/SK12297A3/en unknown
-
1997
- 1997-01-28 FI FI970357A patent/FI970357A/en unknown
- 1997-01-28 NO NO970373A patent/NO307827B1/en not_active IP Right Cessation
- 1997-01-29 OA OA60957A patent/OA10470A/en unknown
-
1998
- 1998-07-27 IL IL12552598A patent/IL125525A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
CA2196079A1 (en) | 1996-02-15 |
IL114759A0 (en) | 1995-12-31 |
AP776A (en) | 1999-10-28 |
CZ25497A3 (en) | 1997-09-17 |
MX9700763A (en) | 1997-05-31 |
SK12297A3 (en) | 1997-08-06 |
NO970373L (en) | 1997-03-18 |
WO1996004260A1 (en) | 1996-02-15 |
DZ1916A1 (en) | 2002-02-17 |
NO970373D0 (en) | 1997-01-28 |
EP0772605A1 (en) | 1997-05-14 |
IL125525A0 (en) | 1999-03-12 |
OA10470A (en) | 2002-04-08 |
BR9508468A (en) | 1997-11-25 |
FI970357A (en) | 1997-03-26 |
HUT76637A (en) | 1997-10-28 |
AP9700918A0 (en) | 1997-01-31 |
WO1996004261A1 (en) | 1996-02-15 |
PL318766A1 (en) | 1997-07-07 |
NO307827B1 (en) | 2000-06-05 |
IL125525A (en) | 2000-02-29 |
FI970357A0 (en) | 1997-01-28 |
MA23632A1 (en) | 1996-04-01 |
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